Identification and characterization of a novel Aspergillus fumigatus rhomboid family putative protease, RbdA, involved in hypoxia sensing and virulence

Infection and Immunity

Volumn 84, Issue 6, 2016, Pages 1866-1878

  Vaknin, Yakir ^a   Hillmann, Falk ^b,c   Iannitti, Rossana ^d   Baruch, Netali Ben ^a   Sandovsky Losica, Hana ^a   Shadkchan, Yona ^a   Romani, Luigina ^d   Brakhage, Axel ^b,c   Kniemeyer, Olaf ^b,c   Osherova, Nir ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b HANS KNÖLL INSTITUTE   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COBALT CHLORIDE; FERROZINE; FLUCONAZOLE; FUNGAL PROTEIN; GAMMA INTERFERON; HELIX LOOP HELIX PROTEIN; NIKKOMYCIN Z; PROTEIN RBDA; PROTEIN SRBA; PROTEINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VORICONAZOLE; ANTIFUNGAL AGENT; COBALT; PEPTIDE HYDROLASE; STEROL REGULATORY ELEMENT BINDING PROTEIN; UBIQUITIN PROTEIN LIGASE;

ADAPTATION; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CELL KILLING; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RESPONSE; ENZYME ANALYSIS; FUNGAL STRUCTURES; FUNGAL VIRULENCE; FUNGUS GROWTH; FUNGUS MUTANT; GALLERIA MELLONELLA; GENE DELETION; HYPOXIA; IN VIVO STUDY; INFECTION SENSITIVITY; INFLAMMATION; LARVA; MOUSE; NEUROSPORA CRASSA; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; SCREENING; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; TRANSCRIPTION REGULATION; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; FEMALE; FUNGUS SPORE; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; LUNG; MALE; MICROBIOLOGY; MOTH; MUTATION; PATHOGENICITY; PATHOLOGY; VIRULENCE;

ANIMALS; ANTIFUNGAL AGENTS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; COBALT; DISEASE MODELS, ANIMAL; FEMALE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HOST-PATHOGEN INTERACTIONS; HYPOXIA; IMMUNOCOMPROMISED HOST; LARVA; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; MOTHS; MUTATION; NEUROSPORA CRASSA; PEPTIDE HYDROLASES; SIGNAL TRANSDUCTION; SPORES, FUNGAL; STEROL REGULATORY ELEMENT BINDING PROTEINS; UBIQUITIN-PROTEIN LIGASES; VIRULENCE;

EID: 84971576952     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00011-16     Document Type: Article

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