A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

Neurobiology of Aging

Volumn 48, Issue , 2016, Pages 34-47

  Lauritzen, Knut H ^a   Hasan Olive, Md Mahdi ^a   Regnell, Christine E ^a,b   Kleppa, Liv ^a   Scheibye Knudsen, Morten ^c   Gjedde, Albert ^b   Klungland, Arne ^a,d   Bohr, Vilhelm A ^c   Storm Mathisen, Jon ^a   Bergersen, Linda H ^a,b  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Biogenesis; Ketogenic diet; MtDNA damage; Neurodegeneration

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; DNA LIGASE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; SIRTUIN 1; UNCLASSIFIED DRUG; UNG1 PROTEIN; PERYLENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; DNA DAMAGE; DOWN REGULATION; ELECTRON MICROSCOPY; FOREBRAIN; KETOGENIC DIET; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL VOLUME; MOUSE; NERVE DEGENERATION; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; UPREGULATION; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CYTOLOGY; GENETICS; METABOLISM; MITOCHONDRIAL DISEASES; MITOCHONDRION; NERVE CELL; NEURODEGENERATIVE DISEASES; ORGANELLE BIOGENESIS; PATHOLOGY; TRANSGENIC MOUSE; ULTRASTRUCTURE;

ANIMALS; DNA DAMAGE; DNA, MITOCHONDRIAL; KETOGENIC DIET; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MITOCHONDRIA; MITOCHONDRIAL DISEASES; NEURODEGENERATIVE DISEASES; NEURONS; ORGANELLE BIOGENESIS; PERYLENE; PROSENCEPHALON;

EID: 84987943301     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2016.08.005     Document Type: Article

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