-
1
-
-
84937738036
-
Homozygous MAPT R406W mutation causing FTDP phenotype: a unique instance of a unique mutation
-
Behnam M., Ghorbani F., Shin J., Kim D., Jang H., Nouri N., Sedghi M., Salehi M., Ansari B. and Basiri K. (2015) Homozygous MAPT R406W mutation causing FTDP phenotype: a unique instance of a unique mutation. Gene 570, 150–152.
-
(2015)
Gene
, vol.570
, pp. 150-152
-
-
Behnam, M.1
Ghorbani, F.2
Shin, J.3
Kim, D.4
Jang, H.5
Nouri, N.6
Sedghi, M.7
Salehi, M.8
Ansari, B.9
Basiri, K.10
-
2
-
-
17844386379
-
Acetogenins from Annonaceae: recent progress in isolation, synthesis and mechanisms of action
-
Bermejo A., Figadère B., Zafra-Polo M., Barrachina I., Estornell E. and Cortes D. (2005) Acetogenins from Annonaceae: recent progress in isolation, synthesis and mechanisms of action. Nat. Prod. Rep. 22, 269–303.
-
(2005)
Nat. Prod. Rep.
, vol.22
, pp. 269-303
-
-
Bermejo, A.1
Figadère, B.2
Zafra-Polo, M.3
Barrachina, I.4
Estornell, E.5
Cortes, D.6
-
3
-
-
84881427415
-
Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet
-
Bhat N. R. and Thirumangalakudi L. (2013) Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet. J. Alzheimers Dis. 36, 781–789.
-
(2013)
J. Alzheimers Dis.
, vol.36
, pp. 781-789
-
-
Bhat, N.R.1
Thirumangalakudi, L.2
-
4
-
-
0032897924
-
A clinical pathological comparison of three families with frontotemporal dementia and identical mutations in the tau gene (P301L)
-
Bird T. D., Nochlin D., Poorkaj P. et al. (1999) A clinical pathological comparison of three families with frontotemporal dementia and identical mutations in the tau gene (P301L). Brain 122(Pt 4), 741–756.
-
(1999)
Brain
, vol.122
, pp. 741-756
-
-
Bird, T.D.1
Nochlin, D.2
Poorkaj, P.3
-
5
-
-
84944903063
-
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy
-
Blair L. J., Frauen H. D., Zhang B. et al. (2015) Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy. Acta Neuropathol. Commun. 3, 8.
-
(2015)
Acta Neuropathol. Commun.
, vol.3
, pp. 8
-
-
Blair, L.J.1
Frauen, H.D.2
Zhang, B.3
-
6
-
-
84892474007
-
Annonaceous acetogenins as environmental neurotoxins: Human exposure from edible Annona fruits
-
Bonneau N., Le Ven J., Schmitz-Afonso I., Guérineau V., Bajin ba Ndob I., Baloul L., Lewin G., Laprévote O., Brunelle A., Touboul D. and Champy P. (2012) Annonaceous acetogenins as environmental neurotoxins: Human exposure from edible Annona fruits. Planta Med. 78, DOI: 10.1055/s-0034-1394993.
-
(2012)
Planta Med.
, vol.78
-
-
Bonneau, N.1
Le Ven, J.2
Schmitz-Afonso, I.3
Guérineau, V.4
Bajin ba Ndob, I.5
Baloul, L.6
Lewin, G.7
Laprévote, O.8
Brunelle, A.9
Touboul, D.10
Champy, P.11
-
7
-
-
84943428482
-
Method development for quantification of the environmental neurotoxin annonacin in Rat plasma by UPLC-MS/MS and application to a pharmacokinetic study
-
Bonneau N., Schmitz-Afonso I., Brunelle A., Touboul D. and Champy P. (2015) Method development for quantification of the environmental neurotoxin annonacin in Rat plasma by UPLC-MS/MS and application to a pharmacokinetic study. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 1004, 46–52.
-
(2015)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.1004
, pp. 46-52
-
-
Bonneau, N.1
Schmitz-Afonso, I.2
Brunelle, A.3
Touboul, D.4
Champy, P.5
-
8
-
-
0033600443
-
Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study
-
Caparros-Lefebvre D. and Elbaz A. (1999) Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Lancet 354, 281–286.
-
(1999)
Lancet
, vol.354
, pp. 281-286
-
-
Caparros-Lefebvre, D.1
Elbaz, A.2
-
9
-
-
0036206405
-
Guadeloupean parkinsonism: a cluster of progressive supranuclear palsy-like tauopathy
-
Caparros-Lefebvre D., Sergeant N., Lees A., Camuzat A., Daniel S., Lannuzel A., Brice A., Tolosa E., Delacourte A. and Duyckaerts C. (2002) Guadeloupean parkinsonism: a cluster of progressive supranuclear palsy-like tauopathy. Brain 125, 801–811.
-
(2002)
Brain
, vol.125
, pp. 801-811
-
-
Caparros-Lefebvre, D.1
Sergeant, N.2
Lees, A.3
Camuzat, A.4
Daniel, S.5
Lannuzel, A.6
Brice, A.7
Tolosa, E.8
Delacourte, A.9
Duyckaerts, C.10
-
10
-
-
9144275011
-
Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe
-
Champy P., Höglinger G. U., Féger J. et al. (2004) Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe. J. Neurochem. 88, 63–69.
-
(2004)
J. Neurochem.
, vol.88
, pp. 63-69
-
-
Champy, P.1
Höglinger, G.U.2
Féger, J.3
-
11
-
-
33644936575
-
Quantification of acetogenins in Annona muricata linked to atypical parkinsonism in guadeloupe
-
Champy P., Melot A., Guérineau V. et al. (2005) Quantification of acetogenins in Annona muricata linked to atypical parkinsonism in guadeloupe. Mov. Disord. 20, 1629–1633.
-
(2005)
Mov. Disord.
, vol.20
, pp. 1629-1633
-
-
Champy, P.1
Melot, A.2
Guérineau, V.3
-
12
-
-
73849125962
-
MALDI-TOF MS profiling of annonaceous acetogenins in Annona muricata products for human consumption
-
Champy P., Guérineau V. and Laprévote O. (2009) MALDI-TOF MS profiling of annonaceous acetogenins in Annona muricata products for human consumption. Molecules 14, 5235–5246.
-
(2009)
Molecules
, vol.14
, pp. 5235-5246
-
-
Champy, P.1
Guérineau, V.2
Laprévote, O.3
-
13
-
-
0037414833
-
Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding
-
Cho J. and Johnson G. V. W. (2003) Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding. J. Biol. Chem. 278, 187–193.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 187-193
-
-
Cho, J.1
Johnson, G.V.W.2
-
15
-
-
21244486781
-
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice
-
David D. C., Hauptmann S., Scherping I. et al. (2005) Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. J. Biol. Chem. 280, 23802–23814.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23802-23814
-
-
David, D.C.1
Hauptmann, S.2
Scherping, I.3
-
16
-
-
20444448544
-
Annonaceous acetogenins: the hydroxyl groups and THF rings are crucial structural elements for targeting the mitochondria, demonstration with the synthesis of fluorescent squamocin analogues
-
Derbré S., Roué G., Poupon E., Susin S. A. and Hocquemiller R. (2005) Annonaceous acetogenins: the hydroxyl groups and THF rings are crucial structural elements for targeting the mitochondria, demonstration with the synthesis of fluorescent squamocin analogues. ChemBioChem 6, 979–982.
-
(2005)
ChemBioChem
, vol.6
, pp. 979-982
-
-
Derbré, S.1
Roué, G.2
Poupon, E.3
Susin, S.A.4
Hocquemiller, R.5
-
17
-
-
3042818863
-
Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation
-
Dougherty C. J., Kubasiak L. A., Frazier D. P., Li H., Xiong W., Bishopric N. H. and Webster K. A. (2004) Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation. FASEB J. 18, 1060–1070.
-
(2004)
FASEB J.
, vol.18
, pp. 1060-1070
-
-
Dougherty, C.J.1
Kubasiak, L.A.2
Frazier, D.P.3
Li, H.4
Xiong, W.5
Bishopric, N.H.6
Webster, K.A.7
-
18
-
-
34447619518
-
Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons
-
Escobar-Khondiker M., Höllerhage M., Muriel M. et al. (2007) Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons. J. Neurosci. 27, 7827–7837.
-
(2007)
J. Neurosci.
, vol.27
, pp. 7827-7837
-
-
Escobar-Khondiker, M.1
Höllerhage, M.2
Muriel, M.3
-
19
-
-
39849106952
-
Differential long-term neurotoxicity of HIV-1 proteins in the rat hippocampal formation: a design-based stereological study
-
Fitting S., Booze R. M., Hasselrot U. and Mactutus C. F. (2008) Differential long-term neurotoxicity of HIV-1 proteins in the rat hippocampal formation: a design-based stereological study. Hippocampus 18, 135–147.
-
(2008)
Hippocampus
, vol.18
, pp. 135-147
-
-
Fitting, S.1
Booze, R.M.2
Hasselrot, U.3
Mactutus, C.F.4
-
20
-
-
0030977392
-
Frontotemporal dementia and parkinsonism linked to chromosome 17: a consensus conference
-
Foster N. L., Wilhelmsen K., Sima A. A., Jones M. Z., D'Amato C. J. and Gilman S. (1997) Frontotemporal dementia and parkinsonism linked to chromosome 17: a consensus conference. Conference Participants. Ann. Neurol. 41, 706–715.
-
(1997)
Conference Participants. Ann. Neurol.
, vol.41
, pp. 706-715
-
-
Foster, N.L.1
Wilhelmsen, K.2
Sima, A.A.3
Jones, M.Z.4
D'Amato, C.J.5
Gilman, S.6
-
21
-
-
79951873381
-
The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner
-
Gauthier-Kemper A., Weissmann C., Golovyashkina N., Sebö-Lemke Z., Drewes G., Gerke V., Heinisch J. J. and Brandt R. (2011) The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner. J. Cell Biol. 192, 647–661.
-
(2011)
J. Cell Biol.
, vol.192
, pp. 647-661
-
-
Gauthier-Kemper, A.1
Weissmann, C.2
Golovyashkina, N.3
Sebö-Lemke, Z.4
Drewes, G.5
Gerke, V.6
Heinisch, J.J.7
Brandt, R.8
-
22
-
-
0030963035
-
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases
-
Goedert M., Hasegawa M., Jakes R., Lawler S., Cuenda A. and Cohen P. (1997) Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases. FEBS Lett. 409, 57–62.
-
(1997)
FEBS Lett.
, vol.409
, pp. 57-62
-
-
Goedert, M.1
Hasegawa, M.2
Jakes, R.3
Lawler, S.4
Cuenda, A.5
Cohen, P.6
-
23
-
-
0033788787
-
Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations
-
Goedert M., Satumtira S., Jakes R., Smith M.J., Kamibayashi C., White 3.C. and Sontag E. (2000) Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations. J. Neurochem. 75, 2155–2162.
-
(2000)
J. Neurochem.
, vol.75
, pp. 2155-2162
-
-
Goedert, M.1
Satumtira, S.2
Jakes, R.3
Smith, M.J.4
Kamibayashi, C.5
White, C.6
Sontag, E.7
-
24
-
-
0032561415
-
Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly
-
Hasegawa M., Smith M. J. and Goedert M. (1998) Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly. FEBS Lett. 437, 207–210.
-
(1998)
FEBS Lett.
, vol.437
, pp. 207-210
-
-
Hasegawa, M.1
Smith, M.J.2
Goedert, M.3
-
25
-
-
0000191231
-
Screening of medicinal plants from Suriname for 5-HT(1A) ligands: bioactive isoquinoline alkaloids from the fruit of Annona muricata
-
Hasrat J. A., Pieters L., De Backer J. P., Vauquelin G. and Vlietinck A. J. (1997) Screening of medicinal plants from Suriname for 5-HT(1A) ligands: bioactive isoquinoline alkaloids from the fruit of Annona muricata. Phytomedicine 4, 133–140.
-
(1997)
Phytomedicine
, vol.4
, pp. 133-140
-
-
Hasrat, J.A.1
Pieters, L.2
De Backer, J.P.3
Vauquelin, G.4
Vlietinck, A.J.5
-
26
-
-
37549037404
-
Layer V neurons in mouse cortex projecting to different targets have distinct physiological properties
-
Hattox A. M. and Nelson S. B. (2007) Layer V neurons in mouse cortex projecting to different targets have distinct physiological properties. J. Neurophysiol. 98, 3330–3340.
-
(2007)
J. Neurophysiol.
, vol.98
, pp. 3330-3340
-
-
Hattox, A.M.1
Nelson, S.B.2
-
27
-
-
28244445138
-
The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy
-
Höglinger G. U., Lannuzel A., Khondiker M. E. et al. (2005) The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy. J. Neurochem. 95, 930–939.
-
(2005)
J. Neurochem.
, vol.95
, pp. 930-939
-
-
Höglinger, G.U.1
Lannuzel, A.2
Khondiker, M.E.3
-
28
-
-
70349798628
-
Natural lipophilic inhibitors of mitochondrial complex I are candidate toxins for sporadic neurodegenerative tau pathologies
-
Höllerhage M., Matusch A., Champy P., Lombès A., Ruberg M., Oertel W. H. and Höglinger G. U. (2009) Natural lipophilic inhibitors of mitochondrial complex I are candidate toxins for sporadic neurodegenerative tau pathologies. Exp. Neurol. 220, 133–142.
-
(2009)
Exp. Neurol.
, vol.220
, pp. 133-142
-
-
Höllerhage, M.1
Matusch, A.2
Champy, P.3
Lombès, A.4
Ruberg, M.5
Oertel, W.H.6
Höglinger, G.U.7
-
29
-
-
84914690114
-
Piericidin A aggravates tau pathology in P301S transgenic mice
-
Höllerhage M., Deck R., De Andrade A. et al. (2014) Piericidin A aggravates tau pathology in P301S transgenic mice. PLoS ONE 9, e113557.
-
(2014)
PLoS ONE
, vol.9
-
-
Höllerhage, M.1
Deck, R.2
De Andrade, A.3
-
30
-
-
78650251838
-
Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration
-
Hoover B. R., Reed M. N., Su J. et al. (2010) Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron 68, 1067–1081.
-
(2010)
Neuron
, vol.68
, pp. 1067-1081
-
-
Hoover, B.R.1
Reed, M.N.2
Su, J.3
-
31
-
-
0032543684
-
Association of missense and 5’-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton M., Lendon C. L., Rizzu P. et al. (1998) Association of missense and 5’-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393, 702–705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
-
32
-
-
19944432508
-
Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice
-
Ikeda M., Shoji M., Kawarai T. et al. (2005) Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice. Am. J. Pathol. 166, 521–531.
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 521-531
-
-
Ikeda, M.1
Shoji, M.2
Kawarai, T.3
-
33
-
-
47949125010
-
Mutational analysis in early-onset familial dementia in the Japanese population. The role of PSEN1 and MAPT R406W mutations
-
Ikeuchi T., Kaneko H., Miyashita A. et al. (2008) Mutational analysis in early-onset familial dementia in the Japanese population. The role of PSEN1 and MAPT R406W mutations. Dement. Geriatr. Cogn. Disord. 26, 43–49.
-
(2008)
Dement. Geriatr. Cogn. Disord.
, vol.26
, pp. 43-49
-
-
Ikeuchi, T.1
Kaneko, H.2
Miyashita, A.3
-
34
-
-
84896733978
-
The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons
-
Iovino M., Pfisterer U., Holton J. L. et al. (2014) The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons. Acta Neuropathol. 127, 283–295.
-
(2014)
Acta Neuropathol.
, vol.127
, pp. 283-295
-
-
Iovino, M.1
Pfisterer, U.2
Holton, J.L.3
-
35
-
-
2442488779
-
Detection and determination of reticuline and N-methylcoclaurine in the Annonaceae family using liquid chromatography-tandem mass spectrometry. J
-
Kotake Y., Okuda K., Kamizono M., Matsumoto N., Tanahashi T., Hara H., Caparros-Lefebvre D. and Ohta S. (2004) Detection and determination of reticuline and N-methylcoclaurine in the Annonaceae family using liquid chromatography-tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci 806, 75–78.
-
(2004)
Chromatogr. B Analyt. Technol. Biomed. Life Sci
, vol.806
, pp. 75-78
-
-
Kotake, Y.1
Okuda, K.2
Kamizono, M.3
Matsumoto, N.4
Tanahashi, T.5
Hara, H.6
Caparros-Lefebvre, D.7
Ohta, S.8
-
36
-
-
0036460998
-
Toxicity of Annonaceae for dopaminergic neurons: potential role in atypical parkinsonism in Guadeloupe
-
Lannuzel A., Michel P. P., Caparros-Lefebvre D., Abaul J., Hocquemiller R. and Ruberg M. (2002) Toxicity of Annonaceae for dopaminergic neurons: potential role in atypical parkinsonism in Guadeloupe. Mov. Disord. 17, 84–90.
-
(2002)
Mov. Disord.
, vol.17
, pp. 84-90
-
-
Lannuzel, A.1
Michel, P.P.2
Caparros-Lefebvre, D.3
Abaul, J.4
Hocquemiller, R.5
Ruberg, M.6
-
37
-
-
0141533187
-
The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism
-
Lannuzel A., Michel P. P., Höglinger G. U. et al. (2003) The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism. Neuroscience 121, 287–296.
-
(2003)
Neuroscience
, vol.121
, pp. 287-296
-
-
Lannuzel, A.1
Michel, P.P.2
Höglinger, G.U.3
-
38
-
-
33947101605
-
Atypical parkinsonism in Guadeloupe: a common risk factor for two closely related phenotypes?
-
Lannuzel A., Höglinger G. U., Verhaeghe S. et al. (2007) Atypical parkinsonism in Guadeloupe: a common risk factor for two closely related phenotypes? Brain 130, 816–827.
-
(2007)
Brain
, vol.130
, pp. 816-827
-
-
Lannuzel, A.1
Höglinger, G.U.2
Verhaeghe, S.3
-
39
-
-
84869065648
-
® using post-column lithium infusion
-
® using post-column lithium infusion. J. Mass Spectrom. 47, 1500–1509.
-
(2012)
J. Mass Spectrom.
, vol.47
, pp. 1500-1509
-
-
Le Ven, J.1
Schmitz-Afonso, I.2
Lewin, G.3
Laprévote, O.4
Brunelle, A.5
Touboul, D.6
Champy, P.7
-
40
-
-
84995355975
-
In vitro phase I metabolism and approach to the distribution of annonacin, a neurotoxic annonaceous acetogenin
-
Le Ven J., Schmitz-Afonso I., Bonneau N., Cresteil T., Akagah B., Lewin G., Brunelle A., Touboul D. and Champy P. (2012a) In vitro phase I metabolism and approach to the distribution of annonacin, a neurotoxic annonaceous acetogenin. Planta Med. 78, doi: 10.1055/s-0032-1321229.
-
(2012)
Planta Med.
, vol.78
-
-
Le Ven, J.1
Schmitz-Afonso, I.2
Bonneau, N.3
Cresteil, T.4
Akagah, B.5
Lewin, G.6
Brunelle, A.7
Touboul, D.8
Champy, P.9
-
41
-
-
49149144140
-
The phytochemistry of the Annonaceae
-
Lebœuf M., Cavé A., Bhaumik P., Mukherjee B. and Mukherjee R. (1980) The phytochemistry of the Annonaceae. Phytochemistry 21, 2783–2813.
-
(1980)
Phytochemistry
, vol.21
, pp. 2783-2813
-
-
Lebœuf, M.1
Cavé, A.2
Bhaumik, P.3
Mukherjee, B.4
Mukherjee, R.5
-
42
-
-
0012235595
-
Alkaloids of Annonaceae. XXIX. Alkaloids of Annona muricata
-
Lebœuf M., Legueut C., Cavé A., Desconclois J. F., Forgacs P. and Jacquemin H. (1981) Alkaloids of Annonaceae. XXIX. Alkaloids of Annona muricata. Planta Med. 42, 37–44.
-
(1981)
Planta Med.
, vol.42
, pp. 37-44
-
-
Lebœuf, M.1
Legueut, C.2
Cavé, A.3
Desconclois, J.F.4
Forgacs, P.5
Jacquemin, H.6
-
44
-
-
0037424245
-
Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production
-
Li N., Ragheb K., Lawler G., Sturgis J., Rajwa B., Melendez J. A. and Robinson J. P. (2003) Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J. Biol. Chem. 278, 8516–8525.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8516-8525
-
-
Li, N.1
Ragheb, K.2
Lawler, G.3
Sturgis, J.4
Rajwa, B.5
Melendez, J.A.6
Robinson, J.P.7
-
45
-
-
41049106547
-
Alzheimer disease-like clinical phenotype in a family with FTDP-17 caused by a MAPT R406W mutation
-
Lindquist S. G., Holm I. E., Schwartz M., Law I., Stokholm J., Batbayli M., Waldemar G. and Nielsen J. E. (2008) Alzheimer disease-like clinical phenotype in a family with FTDP-17 caused by a MAPT R406W mutation. Eur. J. Neurol. 15, 377–385.
-
(2008)
Eur. J. Neurol.
, vol.15
, pp. 377-385
-
-
Lindquist, S.G.1
Holm, I.E.2
Schwartz, M.3
Law, I.4
Stokholm, J.5
Batbayli, M.6
Waldemar, G.7
Nielsen, J.E.8
-
46
-
-
70349983827
-
Genetic testing in familial AD and FTD: mutation and phenotype spectrum in a Danish cohort
-
Lindquist S. G., Schwartz M., Batbayli M., Waldemar G. and Nielsen J. E. (2009) Genetic testing in familial AD and FTD: mutation and phenotype spectrum in a Danish cohort. Clin. Genet. 76, 205–209.
-
(2009)
Clin. Genet.
, vol.76
, pp. 205-209
-
-
Lindquist, S.G.1
Schwartz, M.2
Batbayli, M.3
Waldemar, G.4
Nielsen, J.E.5
-
47
-
-
33646594715
-
Pyrithiamine as a substrate for thiamine pyrophosphokinase
-
Liu J., Timm D. E. and Hurley T. D. (2006) Pyrithiamine as a substrate for thiamine pyrophosphokinase. J. Biol. Chem. 281, 6601–6607.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 6601-6607
-
-
Liu, J.1
Timm, D.E.2
Hurley, T.D.3
-
48
-
-
84856563359
-
Annonamine, a new aporphine alkaloid from the leaves of Annona muricata
-
Matsushige A., Kotake Y., Matsunami K., Otsuka H., Ohta S. and Takeda Y. (2012) Annonamine, a new aporphine alkaloid from the leaves of Annona muricata. Chem. Pharm. Bull. (Tokyo) 60, 257–259.
-
(2012)
Chem. Pharm. Bull. (Tokyo)
, vol.60
, pp. 257-259
-
-
Matsushige, A.1
Kotake, Y.2
Matsunami, K.3
Otsuka, H.4
Ohta, S.5
Takeda, Y.6
-
49
-
-
84958225506
-
Cypermethrin stimulates GSK3β-dependent Aβ and p-tau proteins and cognitive loss in young rats: reduced HB-EGF signaling and downstream neuroinflammation as critical regulators
-
Maurya S. K., Mishra J., Abbas S. and Bandyopadhyay S. (2016) Cypermethrin stimulates GSK3β-dependent Aβ and p-tau proteins and cognitive loss in young rats: reduced HB-EGF signaling and downstream neuroinflammation as critical regulators. Mol. Neurobiol. 53, 968–982.
-
(2016)
Mol. Neurobiol.
, vol.53
, pp. 968-982
-
-
Maurya, S.K.1
Mishra, J.2
Abbas, S.3
Bandyopadhyay, S.4
-
50
-
-
0035131614
-
Molecular analysis of mutant and wild-type tau deposited in the brain affected by the FTDP-17 R406W mutation
-
Miyasaka T., Morishima-Kawashima M., Ravid R., Heutink P., van Swieten J. C., Nagashima K. and Ihara Y. (2001) Molecular analysis of mutant and wild-type tau deposited in the brain affected by the FTDP-17 R406W mutation. Am. J. Pathol. 158, 373–379.
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 373-379
-
-
Miyasaka, T.1
Morishima-Kawashima, M.2
Ravid, R.3
Heutink, P.4
van Swieten, J.C.5
Nagashima, K.6
Ihara, Y.7
-
51
-
-
0030840624
-
Isoquinoline neurotoxins in the brain and Parkinson's disease
-
Nagatsu T. (1997) Isoquinoline neurotoxins in the brain and Parkinson's disease. Neurosci. Res. 29, 99–111.
-
(1997)
Neurosci. Res.
, vol.29
, pp. 99-111
-
-
Nagatsu, T.1
-
52
-
-
0036719858
-
Amine-related neurotoxins in Parkinson's disease: past, present, and future
-
Nagatsu T. (2002) Amine-related neurotoxins in Parkinson's disease: past, present, and future. Neurotoxicol. Teratol. 24, 565–569.
-
(2002)
Neurotoxicol. Teratol.
, vol.24
, pp. 565-569
-
-
Nagatsu, T.1
-
53
-
-
0031149817
-
The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells
-
Oberlies N. H., Croy V. L., Harrison M. L. and McLaughlin J. L. (1997) The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells. Cancer Lett. 115, 73–79.
-
(1997)
Cancer Lett.
, vol.115
, pp. 73-79
-
-
Oberlies, N.H.1
Croy, V.L.2
Harrison, M.L.3
McLaughlin, J.L.4
-
54
-
-
2642517835
-
The tau R406W mutation causes progressive presenile dementia with bitemporal atrophy
-
Ostojic J., Elfgren C., Passant U., Nilsson K., Gustafson L., Lannfelt L. and Froelich Fabre S. (2004) The tau R406W mutation causes progressive presenile dementia with bitemporal atrophy. Dement. Geriatr. Cogn. Disord. 17, 298–301.
-
(2004)
Dement. Geriatr. Cogn. Disord.
, vol.17
, pp. 298-301
-
-
Ostojic, J.1
Elfgren, C.2
Passant, U.3
Nilsson, K.4
Gustafson, L.5
Lannfelt, L.6
Froelich Fabre, S.7
-
55
-
-
2642579845
-
Familial presenile dementia with bitemporal atrophy
-
Passant U., Ostojic J., Froelich Fabre S., Gustafson L., Lannfelt L., Larsson E., Nilsson K., Rosén I. and Elfgren C. (2004) Familial presenile dementia with bitemporal atrophy. Dement. Geriatr. Cogn. Disord. 17, 287–292.
-
(2004)
Dement. Geriatr. Cogn. Disord.
, vol.17
, pp. 287-292
-
-
Passant, U.1
Ostojic, J.2
Froelich Fabre, S.3
Gustafson, L.4
Lannfelt, L.5
Larsson, E.6
Nilsson, K.7
Rosén, I.8
Elfgren, C.9
-
56
-
-
0342368837
-
The FTDP-17-linked mutation R406W abolishes the interaction of phosphorylated tau with microtubules
-
Pérez M., Lim F., Arrasate M. and Avila J. (2000) The FTDP-17-linked mutation R406W abolishes the interaction of phosphorylated tau with microtubules. J. Neurochem. 74, 2583–2589.
-
(2000)
J. Neurochem.
, vol.74
, pp. 2583-2589
-
-
Pérez, M.1
Lim, F.2
Arrasate, M.3
Avila, J.4
-
57
-
-
84930679125
-
High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents
-
Petrov D., Pedrós I., Artiach G. et al. (2015) High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents. Biochim. Biophys. Acta 1852, 1687–1699.
-
(2015)
Biochim. Biophys. Acta
, vol.1852
, pp. 1687-1699
-
-
Petrov, D.1
Pedrós, I.2
Artiach, G.3
-
58
-
-
83155191150
-
Annonacin in Asimina triloba fruit: implication for neurotoxicity
-
Potts L. F., Luzzio F. A., Smith S. C., Hetman M., Champy P. and Litvan I. (2012) Annonacin in Asimina triloba fruit: implication for neurotoxicity. Neurotoxicology 33, 53–58.
-
(2012)
Neurotoxicology
, vol.33
, pp. 53-58
-
-
Potts, L.F.1
Luzzio, F.A.2
Smith, S.C.3
Hetman, M.4
Champy, P.5
Litvan, I.6
-
59
-
-
0242353016
-
Tau (MAPT) mutation Arg406Trp presenting clinically with Alzheimer disease does not share a common founder in Western Europe
-
Rademakers R., Dermaut B., Peeters K., Cruts M., Heutink P., Goate A. and Van Broeckhoven C. (2003) Tau (MAPT) mutation Arg406Trp presenting clinically with Alzheimer disease does not share a common founder in Western Europe. Hum. Mutat. 22, 409–411.
-
(2003)
Hum. Mutat.
, vol.22
, pp. 409-411
-
-
Rademakers, R.1
Dermaut, B.2
Peeters, K.3
Cruts, M.4
Heutink, P.5
Goate, A.6
Van Broeckhoven, C.7
-
60
-
-
62149118687
-
Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease
-
Ramaswamy S., McBride J. L., Han I., Berry-Kravis E. M., Zhou L., Herzog C. D., Gasmi M., Bartus R. T. and Kordower J. H. (2009) Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease. Neurobiol. Dis. 34, 40–50.
-
(2009)
Neurobiol. Dis.
, vol.34
, pp. 40-50
-
-
Ramaswamy, S.1
McBride, J.L.2
Han, I.3
Berry-Kravis, E.M.4
Zhou, L.5
Herzog, C.D.6
Gasmi, M.7
Bartus, R.T.8
Kordower, J.H.9
-
61
-
-
0030826625
-
Autosomal dominant dementia with widespread neurofibrillary tangles
-
Reed L. A., Grabowski T. J., Schmidt M. L. et al. (1997) Autosomal dominant dementia with widespread neurofibrillary tangles. Ann. Neurol. 42, 564–572.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 564-572
-
-
Reed, L.A.1
Grabowski, T.J.2
Schmidt, M.L.3
-
62
-
-
84857034716
-
Selective tau tyrosine nitration in non-AD tauopathies
-
Reyes J. F., Geula C., Vana L. and Binder L. I. (2012) Selective tau tyrosine nitration in non-AD tauopathies. Acta Neuropathol. 123, 119–132.
-
(2012)
Acta Neuropathol.
, vol.123
, pp. 119-132
-
-
Reyes, J.F.1
Geula, C.2
Vana, L.3
Binder, L.I.4
-
63
-
-
0033070197
-
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands
-
Rizzu P., Van Swieten J. C., Joosse M. et al. (1999) High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. Am. J. Hum. Genet. 64, 414–421.
-
(1999)
Am. J. Hum. Genet.
, vol.64
, pp. 414-421
-
-
Rizzu, P.1
Van Swieten, J.C.2
Joosse, M.3
-
64
-
-
22344438508
-
Tau suppression in a neurodegenerative mouse model improves memory function
-
Santacruz K., Lewis J., Spires T. et al. (2005) Tau suppression in a neurodegenerative mouse model improves memory function. Science 309, 476–481.
-
(2005)
Science
, vol.309
, pp. 476-481
-
-
Santacruz, K.1
Lewis, J.2
Spires, T.3
-
65
-
-
24344445346
-
Analysis of benzylisoquinoline-type alkaloids by electrospray tandem mass spectrometry and atmospheric pressure photoionization
-
Schmidt J., Raith K., Boettcher C. and Zenk M. (2005) Analysis of benzylisoquinoline-type alkaloids by electrospray tandem mass spectrometry and atmospheric pressure photoionization. Eur. J. Mass Spectrom. 11, 325–333.
-
(2005)
Eur. J. Mass Spectrom.
, vol.11
, pp. 325-333
-
-
Schmidt, J.1
Raith, K.2
Boettcher, C.3
Zenk, M.4
-
66
-
-
0033789892
-
Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach
-
Schmitz C. and Hof P. R. (2000) Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach. J. Chem. Neuroanat. 20, 93–114.
-
(2000)
J. Chem. Neuroanat.
, vol.20
, pp. 93-114
-
-
Schmitz, C.1
Hof, P.R.2
-
67
-
-
84863393279
-
A current review of cypermethrin-induced neurotoxicity and nigrostriatal dopaminergic neurodegeneration
-
Singh A. K., Tiwari M. N., Prakash O. and Singh M. P. (2012) A current review of cypermethrin-induced neurotoxicity and nigrostriatal dopaminergic neurodegeneration. Curr. Neuropharmacol. 10, 64–71.
-
(2012)
Curr. Neuropharmacol.
, vol.10
, pp. 64-71
-
-
Singh, A.K.1
Tiwari, M.N.2
Prakash, O.3
Singh, M.P.4
-
68
-
-
84927510413
-
Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology
-
Song L., Lu S. X., Ouyang X. et al. (2015) Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology. Mol. Neurodegener. 10, 14.
-
(2015)
Mol. Neurodegener.
, vol.10
, pp. 14
-
-
Song, L.1
Lu, S.X.2
Ouyang, X.3
-
69
-
-
84877906835
-
Tau pathology and neurodegeneration
-
Spillantini M. G. and Goedert M. (2013) Tau pathology and neurodegeneration. Lancet Neurol. 12, 609–622.
-
(2013)
Lancet Neurol.
, vol.12
, pp. 609-622
-
-
Spillantini, M.G.1
Goedert, M.2
-
70
-
-
1542378880
-
Key fragmentation patterns of aporphine alkaloids by electrospray ionization with multistage mass spectrometry
-
Stévigny C., Jiwan J. H., Rozenberg R., de Hoffmann E. and Quetin-Leclercq J. (2004) Key fragmentation patterns of aporphine alkaloids by electrospray ionization with multistage mass spectrometry. Rapid Commun. Mass Spectrom. 18, 523–528.
-
(2004)
Rapid Commun. Mass Spectrom.
, vol.18
, pp. 523-528
-
-
Stévigny, C.1
Jiwan, J.H.2
Rozenberg, R.3
de Hoffmann, E.4
Quetin-Leclercq, J.5
-
71
-
-
0032880430
-
Phenotypic variation in hereditary frontotemporal dementia with tau mutations
-
van Swieten J. C., Stevens M., Rosso S. M. et al. (1999) Phenotypic variation in hereditary frontotemporal dementia with tau mutations. Ann. Neurol. 46, 617–626.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 617-626
-
-
van Swieten, J.C.1
Stevens, M.2
Rosso, S.M.3
-
72
-
-
84923233767
-
Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3β: autoregulation of GSK-3β in vivo
-
Tapia-Rojas C., Schüller A., Lindsay C. B., Ureta R. C., Mejías-Reyes C., Hancke J., Melo F. and Inestrosa N. C. (2015) Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3β: autoregulation of GSK-3β in vivo. Biochem. J 466, 415–430.
-
(2015)
Biochem. J
, vol.466
, pp. 415-430
-
-
Tapia-Rojas, C.1
Schüller, A.2
Lindsay, C.B.3
Ureta, R.C.4
Mejías-Reyes, C.5
Hancke, J.6
Melo, F.7
Inestrosa, N.C.8
-
73
-
-
0037108953
-
Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau
-
Tatebayashi Y., Miyasaka T., Chui D. et al. (2002) Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. Proc. Natl Acad. Sci. USA 99, 13896–13901.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 13896-13901
-
-
Tatebayashi, Y.1
Miyasaka, T.2
Chui, D.3
-
74
-
-
0035958642
-
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles
-
Wittmann C. W., Wszolek M. F., Shulman J. M., Salvaterra P. M., Lewis J., Hutton M. and Feany M. B. (2001) Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science 293, 711–714.
-
(2001)
Science
, vol.293
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
75
-
-
84892467123
-
Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice
-
Yamada E. S., Respondek G., Müssner S. et al. (2014) Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice. Exp. Neurol. 253, 113–125.
-
(2014)
Exp. Neurol.
, vol.253
, pp. 113-125
-
-
Yamada, E.S.1
Respondek, G.2
Müssner, S.3
-
76
-
-
58249135450
-
2 extraction and simultaneous determination of eight annonaceous acetogenins in Annona genus plant seeds by HPLC-DAD method
-
2 extraction and simultaneous determination of eight annonaceous acetogenins in Annona genus plant seeds by HPLC-DAD method. J. Pharm. Biomed. Anal. 49, 140–144.
-
(2009)
J. Pharm. Biomed. Anal.
, vol.49
, pp. 140-144
-
-
Yang, H.1
Li, X.2
Tang, Y.3
Zhang, N.4
Chen, J.5
Cai, B.6
-
77
-
-
33846538660
-
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
-
Yoshiyama Y., Higuchi M., Zhang B., Huang S., Iwata N., Saido T. C., Maeda J., Suhara T., Trojanowski J. Q. and Lee V. M. (2007) Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 53, 337–351.
-
(2007)
Neuron
, vol.53
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.4
Iwata, N.5
Saido, T.C.6
Maeda, J.7
Suhara, T.8
Trojanowski, J.Q.9
Lee, V.M.10
-
78
-
-
2442642836
-
Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy
-
Zhang B., Higuchi M., Yoshiyama Y., Ishihara T., Forman M. S., Martinez D., Joyce S., Trojanowski J. Q. and Lee V. M. (2004) Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy. J. Neurosci. 24, 4657–4667.
-
(2004)
J. Neurosci.
, vol.24
, pp. 4657-4667
-
-
Zhang, B.1
Higuchi, M.2
Yoshiyama, Y.3
Ishihara, T.4
Forman, M.S.5
Martinez, D.6
Joyce, S.7
Trojanowski, J.Q.8
Lee, V.M.9
-
79
-
-
33746883179
-
Characterization of isoquinoline alkaloids, diterpenoids and steroids in the Chinese herb Jin-Guo-Lan (Tinospora sagittata and Tinospora capillipes) by high-performance liquid chromatography/electrospray ionization with multistage mass spectrometry
-
Zhang Y., Shi Q., Shi P., Zhang W. and Cheng Y. (2006) Characterization of isoquinoline alkaloids, diterpenoids and steroids in the Chinese herb Jin-Guo-Lan (Tinospora sagittata and Tinospora capillipes) by high-performance liquid chromatography/electrospray ionization with multistage mass spectrometry. Rapid Commun. Mass Spectrom. 20, 2328–2342.
-
(2006)
Rapid Commun. Mass Spectrom.
, vol.20
, pp. 2328-2342
-
-
Zhang, Y.1
Shi, Q.2
Shi, P.3
Zhang, W.4
Cheng, Y.5
-
80
-
-
79958148893
-
Exposure to pyrithiamine increases β-amyloid accumulation, Tau hyperphosphorylation, and glycogen synthase kinase-3 activity in the brain
-
Zhao J., Sun X., Yu Z., Pan X., Gu F., Chen J., Dong W., Zhao L. and Zhong C. (2011) Exposure to pyrithiamine increases β-amyloid accumulation, Tau hyperphosphorylation, and glycogen synthase kinase-3 activity in the brain. Neurotox. Res. 19, 575–583.
-
(2011)
Neurotox. Res.
, vol.19
, pp. 575-583
-
-
Zhao, J.1
Sun, X.2
Yu, Z.3
Pan, X.4
Gu, F.5
Chen, J.6
Dong, W.7
Zhao, L.8
Zhong, C.9
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