Alzheimer disease-like clinical phenotype in a family with FTDP-17 caused by a MAPT R406W mutation

European Journal of Neurology

Volumn 15, Issue 4, 2008, Pages 377-385

  Lindquist, S G ^a   Holm, I E ^b   Schwartz, M ^c   Law, I ^c   Stokholm, J ^a   Batbayli, M ^c   Waldemar, G ^a   Nielsen, J E ^a  

^a Mental Health Services CPH   (Denmark)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

^c Rigshospitalet   (Denmark)

Author keywords

Autosomal dominant inherited dementia; Clinical phenotype; Frontotemporal dementia; MAPT mutation; Memantine; R406W

Indexed keywords

FLUORODEOXYGLUCOSE F 18; MEMANTINE; TAU PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BRAIN ATROPHY; BRAIN CORTEX; BRAIN DEGENERATION; BRAIN NERVE CELL; BRAIN NUCLEUS; BRAIN SCINTISCANNING; BRAIN STEM; CASE REPORT; CLINICAL FEATURE; DEMENTIA; DISEASE COURSE; FEMALE; FRONTAL CORTEX; FRONTOTEMPORAL DEMENTIA WITH PARKINSONISM LINKED TO CHROMOSOME 17 GENE; GENE; GENE MUTATION; GENETIC COUNSELING; GENETIC HETEROGENEITY; GLUCOSE METABOLISM; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MOLECULAR IMAGING; NEUROFIBRILLARY TANGLE; NEUROIMAGING; NEUROPATHOLOGY; PHENOTYPE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TEMPORAL LOBE;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ARGININE; CHROMOSOMES, HUMAN, PAIR 17; DEMENTIA; DENMARK; DEOXYGLUCOSE; FAMILY HEALTH; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MUTATION; NEUROFIBRILLARY TANGLES; NEUROPSYCHOLOGICAL TESTS; PEPTIDE FRAGMENTS; PHENOTYPE; POSITRON-EMISSION TOMOGRAPHY; TAU PROTEINS; TRYPTOPHAN;

EID: 41049106547     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2008.02069.x     Document Type: Article

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