Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet

Journal of Alzheimer's Disease

Volumn 36, Issue 4, 2013, Pages 781-789

  Bhat, Narayan R ^a   Thirumangalakudi, Lakshmi ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

Author keywords

Brain insulin resistance; dietary fat; hippocampus; insulin IGF signaling; synaptic plasticity; tau phosphorylation

Indexed keywords

DREBRIN; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN KINASE B; SOMATOMEDIN C; TAU PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL DIET; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPUS; HYPERLIPIDEMIA; IMMUNOBLOTTING; INSULIN RESISTANCE; LIPID DIET; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; BRAIN; CHOLESTEROL, DIETARY; DIET, HIGH-FAT; HIPPOCAMPUS; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TAU PROTEINS;

EID: 84881427415     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-121030     Document Type: Article

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