-
1
-
-
12644260466
-
Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase
-
Ryazanov, A. G., Ward, M. D., Mendola, C. E., Pavur, K. S., Dorovkov, M. V., Wiedmann, M., Erdjument-Bromage, H., Tempst, P., Parmer, T. G., Prostko, C. R., Germino, F. J., and Hait, W. N. (1997) Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase. Proc. Natl. Acad. Sci. U.S.A. 94, 4884-4889
-
(1997)
Proc. Natl. Acad. Sci. U. S. A
, vol.94
, pp. 4884-4889
-
-
Ryazanov, A.G.1
Ward, M.D.2
Mendola, C.E.3
Pavur, K.S.4
Dorovkov, M.V.5
Wiedmann, M.6
Erdjument-Bromage, H.7
Tempst, P.8
Parmer, T.G.9
Prostko, C.R.10
Germino, F.J.11
Hait, W.N.12
-
2
-
-
0023884601
-
Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation
-
Ryazanov, A. G., Shestakova, E. A., and Natapov, P. G. (1988) Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation. Nature 334, 170-173
-
(1988)
Nature
, vol.334
, pp. 170-173
-
-
Ryazanov, A.G.1
Shestakova, E.A.2
Natapov, P.G.3
-
3
-
-
0037069352
-
Regulation of elongation factor-2 kinase by pH
-
Dorovkov, M. V., Pavur, K. S., Petrov, A. N., and Ryazanov, A. G. (2002) Regulation of elongation factor-2 kinase by pH. Biochemistry 41, 13444-13450
-
(2002)
Biochemistry
, vol.41
, pp. 13444-13450
-
-
Dorovkov, M.V.1
Pavur, K.S.2
Petrov, A.N.3
Ryazanov, A.G.4
-
4
-
-
1642328617
-
Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398
-
Browne, G. J., Finn, S. G., and Proud, C. G. (2004) Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398. J. Biol. Chem. 279, 12220-12231
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12220-12231
-
-
Browne, G.J.1
Finn, S.G.2
Proud, C.G.3
-
5
-
-
0036314780
-
Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors
-
Patel, J., McLeod, L. E., Vries, R. G. J., Flynn, A., Wang, X., and Proud, C. G. (2002) Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors. Eur. J. Biochem. 269, 3076-3085
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 3076-3085
-
-
Patel, J.1
McLeod, L.E.2
Vries, R.G.J.3
Flynn, A.4
Wang, X.5
Proud, C.G.6
-
6
-
-
39449091637
-
A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death
-
Boyce, M., Py, B. F., Ryazanov, A. G., Minden, J. S., Long, K., Ma, D., and Yuan, J. (2008) A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death. Cell Death Differ. 15, 589-599
-
(2008)
Cell Death Differ.
, vol.15
, pp. 589-599
-
-
Boyce, M.1
Py, B.F.2
Ryazanov, A.G.3
Minden, J.S.4
Long, K.5
Ma, D.6
Yuan, J.7
-
7
-
-
84896720508
-
Germline quality control: EEF2K stands guard to eliminate defective oocytes
-
Chu, H. P., Liao, Y., Novak, J. S., Hu, Z., Merkin, J. J., Shymkiv, Y., Braeckman, B. P., Dorovkov, M. V., Nguyen, A., Clifford, P. M., Nagele, R. G., Harrison, D. E., Ellis, R. E., and Ryazanov, A. G. (2014) Germline quality control: eEF2K stands guard to eliminate defective oocytes. Dev. Cell 28, 561-572
-
(2014)
Dev. Cell.
, vol.28
, pp. 561-572
-
-
Chu, H.P.1
Liao, Y.2
Novak, J.S.3
Hu, Z.4
Merkin, J.J.5
Shymkiv, Y.6
Braeckman, B.P.7
Dorovkov, M.V.8
Nguyen, A.9
Clifford, P.M.10
Nagele, R.G.11
Harrison, D.E.12
Ellis, R.E.13
Ryazanov, A.G.14
-
8
-
-
84878271546
-
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation
-
Leprivier, G., Remke, M., Rotblat, B., Dubuc, A., Mateo, A. R., Kool, M., Agnihotri, S., El-Naggar, A., Yu, B., Somasekharan, S. P., Faubert, B., Bridon, G., Tognon, C. E., Mathers, J., Thomas, R., et al. (2013) The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation. Cell 153, 1064-1079
-
(2013)
Cell
, vol.153
, pp. 1064-1079
-
-
Leprivier, G.1
Remke, M.2
Rotblat, B.3
Dubuc, A.4
Mateo, A.R.5
Kool, M.6
Agnihotri, S.7
El-Naggar, A.8
Yu, B.9
Somasekharan, S.P.10
Faubert, B.11
Bridon, G.12
Tognon, C.E.13
Mathers, J.14
Thomas, R.15
-
9
-
-
84862116855
-
Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress
-
ra
-
Kruiswijk, F., Yuniati, L., Magliozzi, R., Low, T. Y., Lim, R., Bolder, R., Mohammed, S., Proud, C. G., Heck, A. J. R., Pagano, M., and Guardavaccaro, D. (2012) Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress. Sci. Signal. 5, ra40
-
(2012)
Sci. Signal.
, vol.5
, pp. 40
-
-
Kruiswijk, F.1
Yuniati, L.2
Magliozzi, R.3
Low, T.Y.4
Lim, R.5
Bolder, R.6
Mohammed, S.7
Proud, C.G.8
Heck, A.J.R.9
Pagano, M.10
Guardavaccaro, D.11
-
10
-
-
84925491509
-
MTORC1-mediated translational elongation limits intestinal tumour initiation and growth
-
Faller, W. J., Jackson, T. J., Knight, J. R., Ridgway, R. A., Jamieson, T., Karim, S. A., Jones, C., Radulescu, S., Huels, D. J., Myant, K. B., Dudek, K. M., Casey, H. A., Scopelliti, A., Cordero, J. B., Vidal, M., Pende, M., Ryazanov, A. G., Sonenberg, N., Meyuhas, O., Hall, M. N., Bushell, M., Willis, A. E., and Sansom, O. J. (2015) mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature 517, 497-500
-
(2015)
Nature
, vol.517
, pp. 497-500
-
-
Faller, W.J.1
Jackson, T.J.2
Knight, J.R.3
Ridgway, R.A.4
Jamieson, T.5
Karim, S.A.6
Jones, C.7
Radulescu, S.8
Huels, D.J.9
Myant, K.B.10
Dudek, K.M.11
Casey, H.A.12
Scopelliti, A.13
Cordero, J.B.14
Vidal, M.15
Pende, M.16
Ryazanov, A.G.17
Sonenberg, N.18
Meyuhas, O.19
Hall, M.N.20
Bushell, M.21
Willis, A.E.22
Sansom, O.J.23
more..
-
11
-
-
0027285380
-
P53 mutations increase resistance to ionizing radiation
-
Lee, J. M., and Bernstein, A. (1993) P53 mutations increase resistance to ionizing radiation. Proc. Natl. Acad. Sci. U.S.A. 90, 5742-5746
-
(1993)
Proc. Natl. Acad. Sci. U. S. A
, vol.90
, pp. 5742-5746
-
-
Lee, J.M.1
Bernstein, A.2
-
12
-
-
10744228800
-
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
-
Jeffers, J. R., Parganas, E., Lee, Y., Yang, C., Wang, J., Brennan, J., MacLean, K. H., Han, J., Chittenden, T., Ihle, J. N., McKinnon, P. J., Cleveland, J. L., and Zambetti, G. P. (2003) Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell 4, 321-328
-
(2003)
Cancer Cell
, vol.4
, pp. 321-328
-
-
Jeffers, J.R.1
Parganas, E.2
Lee, Y.3
Yang, C.4
Wang, J.5
Brennan, J.6
MacLean, K.H.7
Han, J.8
Chittenden, T.9
Ihle, J.N.10
McKinnon, P.J.11
Cleveland, J.L.12
Zambetti, G.P.13
-
13
-
-
0031663614
-
The relationship between ionizing radiation-induced apoptosis and stem cells in the small and large intestine
-
Potten, C. S., and Grant, H. K. (1998) The relationship between ionizing radiation-induced apoptosis and stem cells in the small and large intestine. Br. J. Cancer 78, 993-1003
-
(1998)
Br. J. Cancer
, vol.78
, pp. 993-1003
-
-
Potten, C.S.1
Grant, H.K.2
-
14
-
-
70350444697
-
The stem cells of small intestinal crypts: Where are they?
-
Potten, C. S., Gandara, R., Mahida, Y. R., Loeffler, M., and Wright, N. A. (2009) The stem cells of small intestinal crypts: where are they? Cell Prolif. 42, 731-750
-
(2009)
Cell Prolif
, vol.42
, pp. 731-750
-
-
Potten, C.S.1
Gandara, R.2
Mahida, Y.R.3
Loeffler, M.4
Wright, N.A.5
-
15
-
-
84880548336
-
The intestinal crypt, a prototype stem cell compartment
-
Clevers, H. (2013) The intestinal crypt, a prototype stem cell compartment. Cell 154, 274-284
-
(2013)
Cell
, vol.154
, pp. 274-284
-
-
Clevers, H.1
-
16
-
-
0030812174
-
Apoptosis in small intestinal epithelial from p53-null mice: Evidence for a delayed, p53-independent G2 /M-associated cell death after γ-irradiation
-
Merritt, A. J., Allen, T. D., Potten, C. S., and Hickman, J. A. (1997) Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2 /M-associated cell death after γ-irradiation. Oncogene 14, 2759-2766
-
(1997)
Oncogene
, vol.14
, pp. 2759-2766
-
-
Merritt, A.J.1
Allen, T.D.2
Potten, C.S.3
Hickman, J.A.4
-
17
-
-
2442681614
-
Dual effect of p53 on radiation sensitivity in vivo: P53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice
-
Komarova, E. A., Kondratov, R. V., Wang, K., Christov, K., Golovkina, T. V., Goldblum, J. R., and Gudkov, A. V. (2004) Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice. Oncogene 23, 3265-3271
-
(2004)
Oncogene
, vol.23
, pp. 3265-3271
-
-
Komarova, E.A.1
Kondratov, R.V.2
Wang, K.3
Christov, K.4
Golovkina, T.V.5
Goldblum, J.R.6
Gudkov, A.V.7
-
18
-
-
0033984235
-
The Ki-67 protein: From the known and the unknown
-
Scholzen, T., and Gerdes, J. (2000) The Ki-67 protein: from the known and the unknown. J. Cell. Physiol. 182, 311-322
-
(2000)
J. Cell. Physiol.
, vol.182
, pp. 311-322
-
-
Scholzen, T.1
Gerdes, J.2
-
19
-
-
75749114436
-
P53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis
-
Kirsch, D. G., Santiago, P. M., di Tomaso, E., Sullivan, J. M., Hou, W. S., Dayton, T., Jeffords, L. B., Sodha, P., Mercer, K. L., Cohen, R., Takeuchi, O., Korsmeyer, S. J., Bronson, R. T., Kim, C. F., Haigis, K. M., Jain, R. K., and Jacks, T. (2010) p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis. Science 327, 593-596
-
(2010)
Science
, vol.327
, pp. 593-596
-
-
Kirsch, D.G.1
Santiago, P.M.2
Di Tomaso, E.3
Sullivan, J.M.4
Hou, W.S.5
Dayton, T.6
Jeffords, L.B.7
Sodha, P.8
Mercer, K.L.9
Cohen, R.10
Takeuchi, O.11
Korsmeyer, S.J.12
Bronson, R.T.13
Kim, C.F.14
Haigis, K.M.15
Jain, R.K.16
Jacks, T.17
-
20
-
-
0037134488
-
Bax and Bak independently promote cytochrome C release from mitochondria
-
Degenhardt, K., Sundararajan, R., Lindsten, T., Thompson, C., and White, E. (2002) Bax and Bak independently promote cytochrome C release from mitochondria. J. Biol. Chem. 277, 14127-14134
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14127-14134
-
-
Degenhardt, K.1
Sundararajan, R.2
Lindsten, T.3
Thompson, C.4
White, E.5
-
21
-
-
34547208851
-
ERK implication in cell cycle regulation
-
Chambard, J. C., Lefloch, R., Pouysségur, J., and Lenormand, P. (2007) ERK implication in cell cycle regulation. Biochim. Biophys. Acta 1773, 1299-1310
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 1299-1310
-
-
Chambard, J.C.1
Lefloch, R.2
Pouysségur, J.3
Lenormand, P.4
-
22
-
-
2342618936
-
Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
-
Liang, J., and Slingerland, J. M. (2003) Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2, 339-345
-
(2003)
Cell Cycle
, vol.2
, pp. 339-345
-
-
Liang, J.1
Slingerland, J.M.2
-
23
-
-
0035736138
-
If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells
-
Roninson, I. B., Broude, E. V., and Chang, B. D. (2001) If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist. Updat. 4, 303-313
-
(2001)
Drug Resist. Updat
, vol.4
, pp. 303-313
-
-
Roninson, I.B.1
Broude, E.V.2
Chang, B.D.3
-
24
-
-
77949450557
-
Mechanisms of druginduced mitotic catastrophe in cancer cells
-
Portugal, J., Mansilla, S., and Bataller, M. (2010) Mechanisms of druginduced mitotic catastrophe in cancer cells. Curr. Pharm. Des. 16, 69-78
-
(2010)
Curr. Pharm. Des.
, vol.16
, pp. 69-78
-
-
Portugal, J.1
Mansilla, S.2
Bataller, M.3
-
25
-
-
0032983271
-
How does radiation kill cells?
-
Jonathan, E. C., Bernhard, E. J., and McKenna, W. G. (1999) How does radiation kill cells? Curr. Opin Chem. Biol. 3, 77-83
-
(1999)
Curr.Opin Chem. Biol.
, vol.3
, pp. 77-83
-
-
Jonathan, E.C.1
Bernhard, E.J.2
McKenna, W.G.3
-
26
-
-
23044467656
-
Two distinct modes of cell death induced by doxorubicin: Apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype
-
Eom, Y. W., Kim, M. A., Park, S. S., Goo, M. J., Kwon, H. J., Sohn, S., Kim, W. H., Yoon, G., and Choi, K. S. (2005) Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype. Oncogene 24, 4765-4777
-
(2005)
Oncogene
, vol.24
, pp. 4765-4777
-
-
Eom, Y.W.1
Kim, M.A.2
Park, S.S.3
Goo, M.J.4
Kwon, H.J.5
Sohn, S.6
Kim, W.H.7
Yoon, G.8
Choi, K.S.9
-
27
-
-
34548101379
-
The mitotic checkpoint in cancer therapy
-
Tao, W. (2005) The mitotic checkpoint in cancer therapy. Cell Cycle 4, 1495-1499
-
(2005)
Cell Cycle
, vol.4
, pp. 1495-1499
-
-
Tao, W.1
-
28
-
-
77953570936
-
Cell cycle re-entry mechanisms after DNA damage checkpoints: Giving it some gas to shut off the breaks!
-
van Vugt, M. A., and Yaffe, M. B. (2010) Cell cycle re-entry mechanisms after DNA damage checkpoints: giving it some gas to shut off the breaks! Cell Cycle 9, 2097-2101
-
(2010)
Cell Cycle
, vol.9
, pp. 2097-2101
-
-
Van Vugt, M.A.1
Yaffe, M.B.2
-
29
-
-
3943107573
-
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
-
Sancar, A., Lindsey-Boltz, L. A., Unsal-Kaçmaz, K., and Linn, S. (2004) Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem. 73, 39-85
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 39-85
-
-
Sancar, A.1
Lindsey-Boltz, L.A.2
Unsal-Kaçmaz, K.3
Linn, S.4
-
30
-
-
70350574128
-
The role of protein synthesis in cell cycling and cancer
-
White-Gilbertson, S., Kurtz, D. T., and Voelkel-Johnson, C. (2009) The role of protein synthesis in cell cycling and cancer. Mol. Oncol. 3, 402-408
-
(2009)
Mol. Oncol.
, vol.3
, pp. 402-408
-
-
White-Gilbertson, S.1
Kurtz, D.T.2
Voelkel-Johnson, C.3
-
31
-
-
41949107421
-
Cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner
-
Smith, E. M., and Proud, C. G. (2008) cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner. EMBO J. 27, 1005-1016
-
(2008)
EMBO J.
, vol.27
, pp. 1005-1016
-
-
Smith, E.M.1
Proud, C.G.2
-
32
-
-
84873050996
-
Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase
-
Hizli, A. A., Chi, Y., Swanger, J., Carter, J. H., Liao, Y., Welcker, M., Ryazanov, A. G., and Clurman, B. E. (2013) Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase. Mol. Cell. Biol. 33, 596-604
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 596-604
-
-
Hizli, A.A.1
Chi, Y.2
Swanger, J.3
Carter, J.H.4
Liao, Y.5
Welcker, M.6
Ryazanov, A.G.7
Clurman, B.E.8
-
33
-
-
1642355123
-
A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin
-
Browne, G. J., and Proud, C. G. (2004) A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin. Mol. Cell. Biol. 24, 2986-2997
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2986-2997
-
-
Browne, G.J.1
Proud, C.G.2
-
34
-
-
0035881470
-
Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase
-
Wang, X., Li, W., Williams, M., Terada, N., Alessi, D. R., and Proud, C. G. (2001) Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. EMBO J. 20, 4370-4379
-
(2001)
EMBO J.
, vol.20
, pp. 4370-4379
-
-
Wang, X.1
Li, W.2
Williams, M.3
Terada, N.4
Alessi, D.R.5
Proud, C.G.6
-
35
-
-
67649438661
-
Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2 /M progression in the cell cycle
-
Nakamura, J., Aoyagi, S., Nanchi, I., Nakatsuka, S., Hirata, E., Shibata, S., Fukuda, M., Yamamoto, Y., Fukuda, I., Tatsumi, N., Ueda, T., Fujiki, F., Nomura, M., Nishida, S., Shirakata, T., et al. (2009) Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2 /M progression in the cell cycle. Int. J. Oncol. 34, 1181-1189
-
(2009)
Int. J. Oncol.
, vol.34
, pp. 1181-1189
-
-
Nakamura, J.1
Aoyagi, S.2
Nanchi, I.3
Nakatsuka, S.4
Hirata, E.5
Shibata, S.6
Fukuda, M.7
Yamamoto, Y.8
Fukuda, I.9
Tatsumi, N.10
Ueda, T.11
Fujiki, F.12
Nomura, M.13
Nishida, S.14
Shirakata, T.15
-
36
-
-
84894531752
-
AMP-activated protein kinase (AMPK) beyond metabolism: A novel genomic stress sensor participating in the DNA damage response pathway
-
Sanli, T., Steinberg, G. R., Singh, G., and Tsakiridis, T. (2014) AMP-activated protein kinase (AMPK) beyond metabolism: a novel genomic stress sensor participating in the DNA damage response pathway. Cancer Biol. Ther. 15, 156-169
-
(2014)
Cancer Biol. Ther.
, vol.15
, pp. 156-169
-
-
Sanli, T.1
Steinberg, G.R.2
Singh, G.3
Tsakiridis, T.4
-
37
-
-
0242410719
-
P53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger, A., Michalak, E. M., Coultas, L., Müllauer, F., Böck, G., Ausserlechner, M. J., Adams, J. M., and Strasser, A. (2003) p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302, 1036-1038
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Müllauer, F.4
Böck, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
38
-
-
0029145730
-
Lethally irradiated mice interleukin-12 protects bone marrow but sensitizes intestinal tract to damage from ionizing radiation
-
discussion 280-271
-
Neta, R., Stiefel, S. M., and Ali, N. (1995) In lethally irradiated mice interleukin-12 protects bone marrow but sensitizes intestinal tract to damage from ionizing radiation. Ann. N.Y. Acad. Sci. 762, 274-280; discussion 280-271
-
(1995)
Ann. N.Y. Acad. Sci.
, vol.762
, pp. 274-280
-
-
Neta, R.1
Stiefel, S.M.2
Ali, N.3
-
39
-
-
0035854479
-
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
-
Paris, F., Fuks, Z., Kang, A., Capodieci, P., Juan, G., Ehleiter, D., Haimovitz-Friedman, A., Cordon-Cardo, C., and Kolesnick, R. (2001) Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 293, 293-297
-
(2001)
Science
, vol.293
, pp. 293-297
-
-
Paris, F.1
Fuks, Z.2
Kang, A.3
Capodieci, P.4
Juan, G.5
Ehleiter, D.6
Haimovitz-Friedman, A.7
Cordon-Cardo, C.8
Kolesnick, R.9
-
40
-
-
79956006207
-
Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21
-
Leibowitz, B. J., Qiu, W., Liu, H., Cheng, T., Zhang, L., and Yu, J. (2011) Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21. Mol. Cancer Res. 9, 616-625
-
(2011)
Mol. Cancer Res
, vol.9
, pp. 616-625
-
-
Leibowitz, B.J.1
Qiu, W.2
Liu, H.3
Cheng, T.4
Zhang, L.5
Yu, J.6
-
41
-
-
84859931417
-
P21 protects Super p53 mice from the radiation-induced gastrointestinal syndrome
-
Sullivan, J. M., Jeffords, L. B., Lee, C. L., Rodrigues, R., Ma, Y., and Kirsch, D. G. (2012) p21 protects "Super p53" mice from the radiation-induced gastrointestinal syndrome. Radiat. Res. 177, 307-310
-
(2012)
Radiat. Res.
, vol.177
, pp. 307-310
-
-
Sullivan, J.M.1
Jeffords, L.B.2
Lee, C.L.3
Rodrigues, R.4
Ma, Y.5
Kirsch, D.G.6
-
42
-
-
44349122954
-
PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome
-
Qiu, W., Carson-Walter, E. B., Liu, H., Epperly, M., Greenberger, J. S., Zambetti, G. P., Zhang, L., and Yu, J. (2008) PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome. Cell Stem Cell 2, 576-583
-
(2008)
Cell Stem Cell
, vol.2
, pp. 576-583
-
-
Qiu, W.1
Carson-Walter, E.B.2
Liu, H.3
Epperly, M.4
Greenberger, J.S.5
Zambetti, G.P.6
Zhang, L.7
Yu, J.8
-
43
-
-
84875533995
-
Cell death signaling and anticancer therapy
-
Galluzzi, L., Vitale, I., Vacchelli, E., and Kroemer, G. (2011) Cell death signaling and anticancer therapy. Front. Oncol. 1, 5
-
(2011)
Front. Oncol
, vol.1
, pp. 5
-
-
Galluzzi, L.1
Vitale, I.2
Vacchelli, E.3
Kroemer, G.4
-
44
-
-
77955001669
-
Radioprotection: Smart games with death
-
Gudkov, A. V., and Komarova, E. A. (2010) Radioprotection: smart games with death. J. Clin. Invest. 120, 2270-2273
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2270-2273
-
-
Gudkov, A.V.1
Komarova, E.A.2
-
45
-
-
50349086198
-
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer
-
Mathew, R., Degenhardt, K., Haramaty, L., Karp, C. M., and White, E. (2008) Immortalized mouse epithelial cell models to study the role of apoptosis in cancer. Methods Enzymol. 446, 77-106
-
(2008)
Methods Enzymol.
, vol.446
, pp. 77-106
-
-
Mathew, R.1
Degenhardt, K.2
Haramaty, L.3
Karp, C.M.4
White, E.5
-
46
-
-
33745960644
-
A mouse model system to genetically dissect the molecular mechanisms regulating tumorigenesis
-
Degenhardt, K., and White, E. (2006) A mouse model system to genetically dissect the molecular mechanisms regulating tumorigenesis. Clin. Cancer Res. 12, 5298-5304
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5298-5304
-
-
Degenhardt, K.1
White, E.2
|