Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure

Circulation Research

Volumn 119, Issue 8, 2016, Pages 944-945

  Sanchez Alonso, Jose L ^a   Bhargava, Anamika ^h   O'Hara, Thomas ^e   Glukhov, Alexey V ^a   Schobesberger, Sophie ^d   Bhogal, Navneet ^a   Sikkel, Markus B ^a   Mansfield, Catherine ^a   Korchev, Yuri E ^b   Lyon, Alexander R ^f   Punjabi, Prakash P ^c   Nikolaev, Viacheslav O ^g   Trayanova, Natalia A ^e   Gorelik, Julia ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b Department of Medicine ^*  (United States)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e Johns Hopkins University   (United States)

^f ROYAL BROMPTON HOSPITAL   (United Kingdom)

^g UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^h INDIAN INSTITUTE OF TECHNOLOGY HYDERABAD   (India)

Author keywords

electrophysiology; heart failure; L Type calcium channel; membrane microdomains; myocardial infarction

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL L TYPE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIAC MUSCLE CELL; CELL MEMBRANE; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; HEART DEPOLARIZATION; HEART FAILURE; HEART REPOLARIZATION; HEART VENTRICLE ARRHYTHMIA; HUMAN; HUMAN CELL; MEMBRANE STRUCTURE; MICROSCOPY; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SARCOLEMMA; SCANNING ION CONDUCTANCE MICROSCOPY; TRANSVERSE TUBULAR SYSTEM; WESTERN BLOTTING; WHOLE CELL PATCH CLAMP; ADULT; AGED; ANIMAL; ARRHYTHMIAS, CARDIAC; CELL CULTURE; FEMALE; MALE; MEMBRANE MICRODOMAIN; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADULT; AGED; ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; FEMALE; HEART FAILURE; HUMANS; MALE; MEMBRANE MICRODOMAINS; MIDDLE AGED; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84987630515     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.308698     Document Type: Article

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