Increased expression of the auxiliary β2-subunit of ventricular L-type Ca2+ channels leads to single-channel activity characteristic of the heart failure

PLoS ONE

Volumn 2, Issue 3, 2007, Pages

  Hullin, Roger ^a   Matthes, Jan ^b   von Vietinghoff, Sibylle ^c,d   Bodi, Ilona ^e   Rubio, Marta ^e   D'Souza, Karen ^e   Khan, Ismail Friedrich ^b   Rottländer, Dennis ^b   Hoppe, Uta C ^b   Mohacsi, Paul ^a   Schmitteckert, Eva ^c   Gilsbach, Ralf ^f   Bünemann, Moritz ^c   Hein, Lutz ^c,f   Schwartz, Arnold ^e   Herzig, Stefan ^b  

^a BERN UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL CAV1.2; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL L TYPE BETA; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; ELECTROPHYSIOLOGY; GENE FUNCTION; GENE OVEREXPRESSION; HEART FAILURE; HEART LEFT VENTRICLE MUSCLE; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN EXPRESSION; TRANSGENIC MOUSE; UPREGULATION; AGING; ANIMAL; CHRONIC DISEASE; GENE EXPRESSION REGULATION; GENETICS; HEART VENTRICLE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALIA; MURINAE; MUS; MUS MUSCULUS;

AGING; ANIMALS; CALCIUM CHANNELS, L-TYPE; CHRONIC DISEASE; GENE EXPRESSION REGULATION; HEART FAILURE; HEART VENTRICLES; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; PHENOTYPE;

EID: 39449101787     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000292     Document Type: Article

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