Reduced effects of BAY K 8644 on L-type Ca2+ current in failing human cardiac myocytes are related to abnormal adrenergic regulation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 294, Issue 5, 2008, Pages

  Chen, Xiongwen ^a   Zhang, Xiaoying ^a   Harris, David M ^a   Piacentino III, Valentino ^b   Berretta, Remus M ^a   Margulies, Kenneth B ^c   Houser, Steven R ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Heart failure; L type calcium channel; Left ventricular assist device

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ACETYLCHOLINE; BUCLADESINE; CALCIUM CHANNEL L TYPE; CATECHOLAMINE; ISOPRENALINE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CACNA1C PROTEIN, HUMAN; CALCIUM CHANNEL STIMULATING AGENT; CARDIOTONIC AGENT; L TYPE CALCIUM CHANNEL ALPHA(1C); L-TYPE CALCIUM CHANNEL ALPHA(1C);

ADRENERGIC SYSTEM; ADULT; AGED; ARTICLE; CALCIUM CURRENT; CATECHOLAMINE RELEASE; CLINICAL ARTICLE; CONTROLLED STUDY; HEART ASSIST DEVICE; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN CELL; INOTROPISM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; CELL MEMBRANE POTENTIAL; DRUG EFFECT; DRUG RESISTANCE; HEART CONTRACTION; HEART VENTRICLE; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ACETYLCHOLINE; ADRENERGIC BETA-AGONISTS; BUCLADESINE; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNELS, L-TYPE; CARDIOTONIC AGENTS; CATECHOLAMINES; DRUG RESISTANCE; HEART FAILURE; HEART VENTRICLES; HEART-ASSIST DEVICES; HUMANS; ISOPROTERENOL; MEMBRANE POTENTIALS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHOSPHORYLATION;

EID: 44949173147     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01335.2007     Document Type: Article

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