Direct evidence for microdomain-specific localization and remodeling of functional L-type calcium channels in rat and human atrial myocytes

Circulation

Volumn 132, Issue 25, 2015, Pages 2372-2384

  Glukhov, Alexey V ^a   Balycheva, Marina ^a,b   Sanchez Alonso, Jose L ^a   Ilkan, Zeki ^a   Alvarez Laviada, Anita ^a   Bhogal, Navneet ^a   Diakonov, Ivan ^a   Schobesberger, Sophie ^a   Sikkel, Markus B ^a   Bhargava, Anamika ^a   Faggian, Giuseppe ^b   Punjabi, Prakash P ^a   Houser, Steven R ^c   Gorelik, Julia ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY OF VERONA   (Italy)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium channels; Cardiac; Heart atria; Heart failure; Myocytes; Scanning ion conductance microscopy; T tubules

Indexed keywords

CALCIUM; CALCIUM CHANNEL L TYPE; METHYL BETA CYCLODEXTRIN;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; ATRIAL MYOCYTE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CAVEOLA; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTRON MICROSCOPY; EXPERIMENTAL HEART FAILURE; HEART ATRIUM; HEART ATRIUM REMODELING; HEART LEFT ATRIUM; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE; HEART RIGHT ATRIUM; HEART VENTRICLE; HUMAN; HUMAN CELL; MEMBRANE DAMAGE; NONHUMAN; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SCANNING ELECTRON MICROSCOPY; SCANNING ION CONDUCTANCE MICROSCOPY; TRANSVERSE TUBULAR SYSTEM; VENTRICULAR MYOCYTE; WHOLE CELL PATCH CLAMP; ANIMAL; CARDIAC MUSCLE CELL; CELL MEMBRANE; CHEMISTRY; PHYSIOLOGY; SPECIES DIFFERENCE;

ANIMALS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; HEART ATRIA; HUMANS; MEMBRANE MICRODOMAINS; MYOCYTES, CARDIAC; RATS; SPECIES SPECIFICITY;

EID: 84953368603     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.115.018131     Document Type: Article

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