A caveolae-targeted L-type Ca 2+ channel antagonist inhibits hypertrophic signaling without reducing cardiac contractility

Circulation Research

Volumn 110, Issue 5, 2012, Pages 669-674

  Makarewich, Catherine A ^a   Correll, Robert N ^b   Gao, Hui ^a   Zhang, Hongyu ^a   Yang, Baohua ^a   Berretta, Remus M ^a   Rizzo, Victor ^a   Molkentin, Jeffery D ^b   Houser, Steven R ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

caveolae; contractility; hypertrophy; L type calcium channel; nuclear factor of activated T cells

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CAVEOLIN 3; PROTEIN; REM PROTEIN; REM PROTEIN[1-265]; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CAVEOLA; FEMALE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; INTRACELLULAR SIGNALING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CARDIOMYOPATHY, HYPERTROPHIC; CATS; CAVEOLAE; CAVEOLIN 3; CELL NUCLEUS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; NFATC TRANSCRIPTION FACTORS; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION;

EID: 84862825070     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.264028     Document Type: Article

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