메뉴 건너뛰기




Volumn 49, Issue 4, 2010, Pages 617-624

Role of CaMKII in RyR leak, EC coupling and action potential duration: A computational model

Author keywords

CaMKII; Computational model; EC coupling; L type Ca channel; RyR

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL L TYPE; CALCIUM ION; RYANODINE RECEPTOR;

EID: 77956191808     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2010.07.011     Document Type: Article
Times cited : (49)

References (50)
  • 1
    • 0028101383 scopus 로고
    • Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium
    • Hasenfuss G., Reinecke H., Studer R., Meyer M., Pieske B., Holtz J., et al. Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium. Circ Res 1994, 75(3):434-442.
    • (1994) Circ Res , vol.75 , Issue.3 , pp. 434-442
    • Hasenfuss, G.1    Reinecke, H.2    Studer, R.3    Meyer, M.4    Pieske, B.5    Holtz, J.6
  • 2
    • 0033583244 scopus 로고    scopus 로고
    • Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure: I. Experimental studies
    • O'Rourke B., Kass D.A., Tomaselli G.F., Kaab S., Tunin R., Marban E. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure: I. Experimental studies. Circ Res 1999, 84(5):562-570.
    • (1999) Circ Res , vol.84 , Issue.5 , pp. 562-570
    • O'Rourke, B.1    Kass, D.A.2    Tomaselli, G.F.3    Kaab, S.4    Tunin, R.5    Marban, E.6
  • 4
    • 0034640113 scopus 로고    scopus 로고
    • PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
    • Marx S.O., Reiken S., Hisamatsu Y., Jayaraman T., Burkhoff D., Rosemblit N., et al. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 2000, 101(4):365-376.
    • (2000) Cell , vol.101 , Issue.4 , pp. 365-376
    • Marx, S.O.1    Reiken, S.2    Hisamatsu, Y.3    Jayaraman, T.4    Burkhoff, D.5    Rosemblit, N.6
  • 5
    • 0141752833 scopus 로고    scopus 로고
    • 2+ leak in intact ventricular myocytes from rabbits in heart failure
    • 2+ leak in intact ventricular myocytes from rabbits in heart failure. Circ Res 2003, 93(7):592-594.
    • (2003) Circ Res , vol.93 , Issue.7 , pp. 592-594
    • Shannon, T.R.1    Pogwizd, S.M.2    Bers, D.M.3
  • 6
    • 33644865926 scopus 로고    scopus 로고
    • Increased sarcoplasmic reticulum calcium leak but unaltered contractility by acute CaMKII overexpression in isolated rabbit cardiac myocytes
    • Kohlhaas M., Zhang T., Seidler T., Zibrova D., Dybkova N., Steen A., et al. Increased sarcoplasmic reticulum calcium leak but unaltered contractility by acute CaMKII overexpression in isolated rabbit cardiac myocytes. Circ Res 2006, 98(2):235-244.
    • (2006) Circ Res , vol.98 , Issue.2 , pp. 235-244
    • Kohlhaas, M.1    Zhang, T.2    Seidler, T.3    Zibrova, D.4    Dybkova, N.5    Steen, A.6
  • 7
    • 36849057068 scopus 로고    scopus 로고
    • Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials
    • Grandi E., Puglisi J.L., Wagner S., Maier L.S., Severi S., Bers D.M. Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials. Biophys J 2007, 93(11):3835-3847.
    • (2007) Biophys J , vol.93 , Issue.11 , pp. 3835-3847
    • Grandi, E.1    Puglisi, J.L.2    Wagner, S.3    Maier, L.S.4    Severi, S.5    Bers, D.M.6
  • 9
    • 8744246332 scopus 로고    scopus 로고
    • Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model
    • Hund T.J., Rudy Y. Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model. Circulation 2004, 110(20):3168-3174.
    • (2004) Circulation , vol.110 , Issue.20 , pp. 3168-3174
    • Hund, T.J.1    Rudy, Y.2
  • 10
    • 58149280497 scopus 로고    scopus 로고
    • Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes. Biophys J 2008;95(10):4597-612
    • Saucerman JJ, Bers DM. Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes. Biophys J 2008;95(10):4597-612.
    • Saucerman, J.J.1    Bers, D.M.2
  • 11
    • 0025772161 scopus 로고
    • Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity
    • Witcher D.R., Kovacs R.J., Schulman H., Cefali D.C., Jones L.R. Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity. J Biol Chem 1991, 266(17):11144-11152.
    • (1991) J Biol Chem , vol.266 , Issue.17 , pp. 11144-11152
    • Witcher, D.R.1    Kovacs, R.J.2    Schulman, H.3    Cefali, D.C.4    Jones, L.R.5
  • 12
    • 33747431210 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II phosphorylation of ryanodine receptor does affect calcium sparks in mouse ventricular myocytes
    • 2+/calmodulin-dependent protein kinase II phosphorylation of ryanodine receptor does affect calcium sparks in mouse ventricular myocytes. Circ Res 2006, 99(4):398-406.
    • (2006) Circ Res , vol.99 , Issue.4 , pp. 398-406
    • Guo, T.1    Zhang, T.2    Mestril, R.3    Bers, D.M.4
  • 13
    • 0028918056 scopus 로고
    • Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle
    • Hain J., Onoue H., Mayrleitner M., Fleischer S., Schindler H. Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle. J Biol Chem 1995, 270(5):2074-2081.
    • (1995) J Biol Chem , vol.270 , Issue.5 , pp. 2074-2081
    • Hain, J.1    Onoue, H.2    Mayrleitner, M.3    Fleischer, S.4    Schindler, H.5
  • 14
    • 0029080486 scopus 로고
    • Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism
    • Lokuta A.J., Rogers T.B., Lederer W.J., Valdivia H.H. Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism. J Physiol 1995, 487(Pt_3):609-622.
    • (1995) J Physiol , vol.487 , Issue.PART 3 , pp. 609-622
    • Lokuta, A.J.1    Rogers, T.B.2    Lederer, W.J.3    Valdivia, H.H.4
  • 17
    • 0033781028 scopus 로고    scopus 로고
    • Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels
    • Dzhura I., Wu Y., Colbran R.J., Balser J.R., Anderson M.E. Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat Cell Biol 2000, 2(3):173-177.
    • (2000) Nat Cell Biol , vol.2 , Issue.3 , pp. 173-177
    • Dzhura, I.1    Wu, Y.2    Colbran, R.J.3    Balser, J.R.4    Anderson, M.E.5
  • 18
    • 33644870558 scopus 로고    scopus 로고
    • Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helices
    • Erxleben C., Liao Y., Gentile S., Chin D., Gomez-Alegria C., Mori Y., et al. Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helices. Proc Natl Acad Sci 2006, 103(10):3932-3937.
    • (2006) Proc Natl Acad Sci , vol.103 , Issue.10 , pp. 3932-3937
    • Erxleben, C.1    Liao, Y.2    Gentile, S.3    Chin, D.4    Gomez-Alegria, C.5    Mori, Y.6
  • 19
    • 16344373083 scopus 로고    scopus 로고
    • A mathematical treatment of integrated Ca dynamics within the ventricular myocyte
    • Shannon T.R., Wang F., Puglisi J., Weber C., Bers D.M. A mathematical treatment of integrated Ca dynamics within the ventricular myocyte. Biophys J 2004, 87(5):3351-3371.
    • (2004) Biophys J , vol.87 , Issue.5 , pp. 3351-3371
    • Shannon, T.R.1    Wang, F.2    Puglisi, J.3    Weber, C.4    Bers, D.M.5
  • 20
    • 52349122729 scopus 로고    scopus 로고
    • Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes
    • Huke S., Bers D.M. Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes. Biochem Biophys Res Commun 2008, 376(1):80-85.
    • (2008) Biochem Biophys Res Commun , vol.376 , Issue.1 , pp. 80-85
    • Huke, S.1    Bers, D.M.2
  • 21
    • 3042763171 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor
    • 2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor. Circ Res 2004, 94(6):e61-e70.
    • (2004) Circ Res , vol.94 , Issue.6
    • Wehrens, X.H.T.1    Lehnart, S.E.2    Reiken, S.R.3    Marks, A.R.4
  • 22
    • 33847363658 scopus 로고    scopus 로고
    • Temporal dissociation of frequency-dependent acceleration of relaxation and protein phosphorylation by CaMKII
    • Huke S., Bers D.M. Temporal dissociation of frequency-dependent acceleration of relaxation and protein phosphorylation by CaMKII. J Mol Cell Cardiol 2007, 42(3):590-599.
    • (2007) J Mol Cell Cardiol , vol.42 , Issue.3 , pp. 590-599
    • Huke, S.1    Bers, D.M.2
  • 23
    • 0018758359 scopus 로고
    • Mechanism by which cyclic adenosine 3':5'-monophosphate-dependent protein kinase stimulates calcium transport in cardiac sarcoplasmic reticulum
    • Hicks M.J., Shigekawa M., Katz A.M. Mechanism by which cyclic adenosine 3':5'-monophosphate-dependent protein kinase stimulates calcium transport in cardiac sarcoplasmic reticulum. Circ Res 1979, 44(3):384-391.
    • (1979) Circ Res , vol.44 , Issue.3 , pp. 384-391
    • Hicks, M.J.1    Shigekawa, M.2    Katz, A.M.3
  • 24
    • 0034031592 scopus 로고    scopus 로고
    • Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes
    • Shannon T.R., Ginsburg K.S., Bers D.M. Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes. Biophys J 2000, 78(1):322-333.
    • (2000) Biophys J , vol.78 , Issue.1 , pp. 322-333
    • Shannon, T.R.1    Ginsburg, K.S.2    Bers, D.M.3
  • 25
    • 0024309857 scopus 로고
    • Purification and characterization of a calcium-calmodulin-dependent phospholamban kinase from canine myocardium
    • Gupta R.C., Kranias E.G. Purification and characterization of a calcium-calmodulin-dependent phospholamban kinase from canine myocardium. Biochemistry 1989, 28(14):5909-5916.
    • (1989) Biochemistry , vol.28 , Issue.14 , pp. 5909-5916
    • Gupta, R.C.1    Kranias, E.G.2
  • 26
    • 0026016543 scopus 로고
    • Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban
    • Macdougall L.K., Jones L.R., Cohen P. Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban. Eur J Biochem 1991, 196(3):725-734.
    • (1991) Eur J Biochem , vol.196 , Issue.3 , pp. 725-734
    • Macdougall, L.K.1    Jones, L.R.2    Cohen, P.3
  • 30
    • 0027979619 scopus 로고
    • Local control of excitation-contraction coupling in rat heart cells
    • Wier W.G., Egan T.M., López-López J.R., Balke C.W. Local control of excitation-contraction coupling in rat heart cells. J Physiol 1994, 474(3):463-471.
    • (1994) J Physiol , vol.474 , Issue.3 , pp. 463-471
    • Wier, W.G.1    Egan, T.M.2    López-López, J.R.3    Balke, C.W.4
  • 31
    • 0033515617 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium
    • 2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium. Circ Res 1999, 84(6):713-721.
    • (1999) Circ Res , vol.84 , Issue.6 , pp. 713-721
    • Hoch, B.1    Meyer, R.2    Hetzer, R.3    Krause, E.-G.4    Karczewski, P.5
  • 32
    • 0032897465 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase in failing and nonfailing human hearts
    • 2+/calmodulin-dependent protein kinase in failing and nonfailing human hearts. Cardiovasc Res 1999, 42(1):254-261.
    • (1999) Cardiovasc Res , vol.42 , Issue.1 , pp. 254-261
    • Kirchhefer, U.1    Schmitz, W.2    Scholz, H.3    Neumann, J.4
  • 34
    • 0032029144 scopus 로고    scopus 로고
    • Stimulation of Ca-induced Ca release only transiently increases the systolic Ca transient: measurements of Ca fluxes and sarcoplasmic reticulum Ca
    • Trafford A.W., Dieaz M.E., Eisner D.A. Stimulation of Ca-induced Ca release only transiently increases the systolic Ca transient: measurements of Ca fluxes and sarcoplasmic reticulum Ca. Cardiovasc Res 1998, 37(3):710-717.
    • (1998) Cardiovasc Res , vol.37 , Issue.3 , pp. 710-717
    • Trafford, A.W.1    Dieaz, M.E.2    Eisner, D.A.3
  • 35
    • 33847058737 scopus 로고    scopus 로고
    • {beta}-Adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase
    • Curran J., Hinton M.J., Rios E., Bers D.M., Shannon T.R. {beta}-Adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase. Circ Res 2007, 100(3):391-398.
    • (2007) Circ Res , vol.100 , Issue.3 , pp. 391-398
    • Curran, J.1    Hinton, M.J.2    Rios, E.3    Bers, D.M.4    Shannon, T.R.5
  • 37
    • 74249087588 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure
    • Sag C.M., Wadsack D.P., Khabbazzadeh S., Abesser M., Grefe C., Neumann K., et al. Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure. Circ Heart Fail 2009, 2(6):664-675.
    • (2009) Circ Heart Fail , vol.2 , Issue.6 , pp. 664-675
    • Sag, C.M.1    Wadsack, D.P.2    Khabbazzadeh, S.3    Abesser, M.4    Grefe, C.5    Neumann, K.6
  • 38
    • 33846117456 scopus 로고    scopus 로고
    • Increasing ryanodine receptor open probability alone does not produce arrhythmogenic calcium waves: threshold sarcoplasmic reticulum calcium content is required
    • Venetucci L.A., Trafford A.W., Eisner D.A. Increasing ryanodine receptor open probability alone does not produce arrhythmogenic calcium waves: threshold sarcoplasmic reticulum calcium content is required. Circ Res 2007, 100(1):105-111.
    • (2007) Circ Res , vol.100 , Issue.1 , pp. 105-111
    • Venetucci, L.A.1    Trafford, A.W.2    Eisner, D.A.3
  • 39
    • 0030016356 scopus 로고    scopus 로고
    • Dynamic modulation of excitation-contraction coupling by protein phosphatases in rat ventricular myocytes
    • duBell W.H., Lederer W.J., Rogers T.B. Dynamic modulation of excitation-contraction coupling by protein phosphatases in rat ventricular myocytes. J Physiol 1996, 493(Pt 3):793-800.
    • (1996) J Physiol , vol.493 , Issue.PART 3 , pp. 793-800
    • duBell, W.H.1    Lederer, W.J.2    Rogers, T.B.3
  • 40
    • 0032839459 scopus 로고    scopus 로고
    • 2+ release units and couplons in skeletal and cardiac muscles
    • 2+ release units and couplons in skeletal and cardiac muscles. Biophys J 1999, 77(3):1528-1539.
    • (1999) Biophys J , vol.77 , Issue.3 , pp. 1528-1539
    • Franzini-Armstrong, C.1    Protasi, F.2    Ramesh, V.3
  • 42
    • 33646128234 scopus 로고    scopus 로고
    • Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte
    • Greenstein J.L., Hinch R., Winslow R.L. Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte. Biophys J 2006, 90(1):77-91.
    • (2006) Biophys J , vol.90 , Issue.1 , pp. 77-91
    • Greenstein, J.L.1    Hinch, R.2    Winslow, R.L.3
  • 44
    • 0021243501 scopus 로고
    • Calcium-induced calcium release from purified cardiac sarcoplasmic reticulum vesicles. General characteristics
    • Chamberlain B.K., Volpe P., Fleischer S. Calcium-induced calcium release from purified cardiac sarcoplasmic reticulum vesicles. General characteristics. J Biol Chem 1984, 259(12):7540-7546.
    • (1984) J Biol Chem , vol.259 , Issue.12 , pp. 7540-7546
    • Chamberlain, B.K.1    Volpe, P.2    Fleischer, S.3
  • 45
    • 0021914538 scopus 로고
    • Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell
    • Fabiato A. Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell. J Gen Physiol 1985, 85(2):247-289.
    • (1985) J Gen Physiol , vol.85 , Issue.2 , pp. 247-289
    • Fabiato, A.1
  • 46
    • 0025921997 scopus 로고
    • ++ release from rat cardiac and rabbit skeletal muscle sarcoplasmic reticulum
    • ++ release from rat cardiac and rabbit skeletal muscle sarcoplasmic reticulum. J Pharmacol Exp Ther 1991, 256(3):938-946.
    • (1991) J Pharmacol Exp Ther , vol.256 , Issue.3 , pp. 938-946
    • Zimãnyi, I.1    Pessah, I.N.2
  • 47
    • 0141448292 scopus 로고    scopus 로고
    • 2+ sensing sites
    • 2+ sensing sites. Biophys J 1998, 75(6):2801-2810.
    • (1998) Biophys J , vol.75 , Issue.6 , pp. 2801-2810
    • Gyorke, I.1    Gyorke, S.2
  • 50
    • 41449091381 scopus 로고    scopus 로고
    • Partial inhibition of sarcoplasmic reticulum Ca release evokes long-lasting Ca release events in ventricular myocytes: role of luminal Ca in termination of Ca release
    • Zima A.V., Picht E., Bers D.M., Blatter L.A. Partial inhibition of sarcoplasmic reticulum Ca release evokes long-lasting Ca release events in ventricular myocytes: role of luminal Ca in termination of Ca release. Biophys J 2008, 94(5):1867-1879.
    • (2008) Biophys J , vol.94 , Issue.5 , pp. 1867-1879
    • Zima, A.V.1    Picht, E.2    Bers, D.M.3    Blatter, L.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.