-
1
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe, D. J. Alzheimer's disease is a synaptic failure. Science 298, 789-791, doi: 10.1126/science.1074069 (2002).
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
2
-
-
84859755505
-
Alzheimer's disease and the amyloid cascade hypo thesis: A critical review
-
Reitz, C. Alzheimer's disease and the amyloid cascade hypothesis: a critical review. Int J Alzheimers Dis 2012, 369808, doi: 10.1155/2012/369808 (2012).
-
(2012)
Int J Alzheimers Dis
, vol.2012
, pp. 369808
-
-
Reitz, C.1
-
3
-
-
84929890412
-
The case for rejecting the amyloid cascade hypothesis
-
Herrup, K. The case for rejecting the amyloid cascade hypothesis. Nat Neurosci 18, 794-799, doi: 10.1038/nn.4017 (2015).
-
(2015)
Nat Neurosci
, vol.18
, pp. 794-799
-
-
Herrup, K.1
-
4
-
-
84921692098
-
Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer's disease
-
Castello, M. A., Jeppson, J. D. & Soriano, S. Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer's disease. BMC Neurol 14, 169, doi: 10.1186/s12883-014-0169-0 (2014).
-
(2014)
BMC Neurol
, vol.14
, pp. 169
-
-
Castello, M.A.1
Jeppson, J.D.2
Soriano, S.3
-
5
-
-
84940933988
-
The keystone of Alzheimer pathogenesis might be sought in A physiology
-
Puzzo, D., Gulisano, W., Arancio, O. & Palmeri, A. The keystone of Alzheimer pathogenesis might be sought in A physiology. Neuroscience 307, 26-36 (2015).
-
(2015)
Neuroscience
, vol.307
, pp. 26-36
-
-
Puzzo, D.1
Gulisano, W.2
Arancio, O.3
Palmeri, A.4
-
6
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
-
Terry, R. D. et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30, 572-580, doi: 10.1002/ana.410300410 (1991).
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
-
7
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada, P. V., Growdon, J. H., Hedley-Whyte, E. T. & Hyman, B. T. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 42, 631-639 (1992).
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-Whyte, E.T.3
Hyman, B.T.4
-
8
-
-
0029078972
-
Correlations of synaptic and pathological markers with cognition of the elderly
-
discussion 298-304
-
Dickson, D. W. et al. Correlations of synaptic and pathological markers with cognition of the elderly. Neurobiol Aging 16, 285-298; discussion 298-304 (1995).
-
(1995)
Neurobiol Aging
, vol.16
, pp. 285-298
-
-
Dickson, D.W.1
-
9
-
-
0030815429
-
Lack of correlation between plaque burden and cognition in the aged monkey
-
Sloane, J. A. et al. Lack of correlation between plaque burden and cognition in the aged monkey. Acta Neuropathol 94, 471-478 (1997).
-
(1997)
Acta Neuropathol
, vol.94
, pp. 471-478
-
-
Sloane, J.A.1
-
10
-
-
0023905906
-
Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques
-
Katzman, R. et al. Clinical, pathological, and neurochemical changes in dementia: a subgroup with preserved mental status and numerous neocortical plaques. Ann Neurol 23, 138-144, doi: 10.1002/ana.410230206 (1988).
-
(1988)
Ann Neurol
, vol.23
, pp. 138-144
-
-
Katzman, R.1
-
11
-
-
0025289562
-
Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person
-
Delaere, P. et al. Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person. Neurosci Lett 116, 87-93 (1990).
-
(1990)
Neurosci Lett
, vol.116
, pp. 87-93
-
-
Delaere, P.1
-
12
-
-
0026070557
-
Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert
-
Wallace, W. C. et al. Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert. Brain Res Mol Brain Res 10, 173-178 (1991).
-
(1991)
Brain Res Mol Brain Res
, vol.10
, pp. 173-178
-
-
Wallace, W.C.1
-
13
-
-
0027482350
-
Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury
-
Gentleman, S. M., Nash, M. J., Sweeting, C. J., Graham, D. I. & Roberts, G. W. Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury. Neurosci Lett 160, 139-144 (1993).
-
(1993)
Neurosci Lett
, vol.160
, pp. 139-144
-
-
Gentleman, S.M.1
Nash, M.J.2
Sweeting, C.J.3
Graham, D.I.4
Roberts, G.W.5
-
14
-
-
0028670780
-
Increased numbers of beta APP-immunoreactive neurones in the entorhinal cortex after head injury
-
McKenzie, J. E., Gentleman, S. M., Roberts, G. W., Graham, D. I. & Royston, M. C. Increased numbers of beta APP-immunoreactive neurones in the entorhinal cortex after head injury. Neuroreport 6, 161-164 (1994).
-
(1994)
Neuroreport
, vol.6
, pp. 161-164
-
-
McKenzie, J.E.1
Gentleman, S.M.2
Roberts, G.W.3
Graham, D.I.4
Royston, M.C.5
-
15
-
-
0028174629
-
Beta amyloid protein deposition in the brain after severe head injury: Implications for the pathogenesis of Alzheimer's disease
-
Roberts, G. W. et al. Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease. J Neurol Neurosurg Psychiatry 57, 419-425 (1994).
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 419-425
-
-
Roberts, G.W.1
-
16
-
-
0028270318
-
Immunoreactive changes resulting from dopaminergic denervation of the dentate gyrus of the rat hippocampal formation
-
Torack, R. M. & Miller, J. W. Immunoreactive changes resulting from dopaminergic denervation of the dentate gyrus of the rat hippocampal formation. Neurosci Lett 169, 9-12 (1994).
-
(1994)
Neurosci Lett
, vol.169
, pp. 9-12
-
-
Torack, R.M.1
Miller, J.W.2
-
17
-
-
84924262484
-
Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease
-
Xia, D. et al. Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease. Neuron 85, 967-981, doi: 10.1016/j.neuron.2015.02.010 (2015).
-
(2015)
Neuron
, vol.85
, pp. 967-981
-
-
Xia, D.1
-
18
-
-
0026781306
-
The role of amyloid beta-protein in Alzheimer's disease
-
Regland, B. & Gottfries, C. G. The role of amyloid beta-protein in Alzheimer's disease. Lancet 340, 467-469 (1992).
-
(1992)
Lancet
, vol.340
, pp. 467-469
-
-
Regland, B.1
Gottfries, C.G.2
-
19
-
-
48749089723
-
Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease
-
Trinchese, F. et al. Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease. J Clin Invest 118, 2796-2807, doi: 10.1172/JCI34254 (2008).
-
(2008)
J Clin Invest
, vol.118
, pp. 2796-2807
-
-
Trinchese, F.1
-
20
-
-
84949983800
-
Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease
-
Fa, M. et al. Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease. J Alzheimers Dis 49, 707-721, doi: 10.3233/JAD-150618 (2015).
-
(2015)
J Alzheimers Dis
, vol.49
, Issue.707-721
-
-
Fa, M.1
-
21
-
-
84926312823
-
Amyloid beta oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis
-
Viola, K. L. & Klein, W. L. Amyloid beta oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis. Acta Neuropathol 129, 183-206, doi: 10.1007/s00401-015-1386-3 (2015).
-
(2015)
Acta Neuropathol
, vol.129
, pp. 183-206
-
-
Viola, K.L.1
Klein, W.L.2
-
22
-
-
0344672942
-
APP processing and synaptic function
-
Kamenetz, F. et al. APP processing and synaptic function. Neuron 37, 925-937 (2003).
-
(2003)
Neuron
, vol.37
, pp. 925-937
-
-
Kamenetz, F.1
-
23
-
-
29144487182
-
Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo
-
Cirrito, J. R. et al. Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. Neuron 48, 913-922, doi: 10.1016/j. neuron.2005.10.028 (2005).
-
(2005)
Neuron
, vol.48
, pp. 913-922
-
-
Cirrito, J.R.1
-
24
-
-
58149385218
-
Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus
-
Puzzo, D. et al. Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus. J Neurosci 28, 14537-14545, doi: 10.1523/JNEUROSCI.2692-08.2008 (2008).
-
(2008)
J Neurosci
, vol.28
, pp. 14537-14545
-
-
Puzzo, D.1
-
25
-
-
77049107345
-
A physiological role for amyloid-beta protein:enhancement of learning and memory
-
Morley, J. E. et al. A physiological role for amyloid-beta protein:enhancement of learning and memory. J Alzheimers Dis 19, 441-449, doi: 10.3233/JAD-2009-1230 (2010).
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 441-449
-
-
Morley, J.E.1
-
26
-
-
84908081507
-
Regulation of presynaptic Ca2+, synaptic plasticity and contextual fear conditioning by a N-terminal betaamyloid fragment
-
Lawrence, J. L. et al. Regulation of presynaptic Ca2+, synaptic plasticity and contextual fear conditioning by a N-terminal betaamyloid fragment. J Neurosci 34, 14210-14218, doi: 10.1523/JNEUROSCI.0326-14.2014 (2014).
-
(2014)
J Neurosci
, vol.34
, pp. 14210-14218
-
-
Lawrence, J.L.1
-
27
-
-
21144447065
-
Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases
-
Mastrangelo, P. et al. Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases. Proc Natl Acad Sci USA 102, 8972-8977, doi: 10.1073/pnas.0500940102 (2005).
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8972-8977
-
-
Mastrangelo, P.1
-
28
-
-
35448942648
-
The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease
-
Giedraitis, V. et al. The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease. Neurosci Lett 427, 127-131, doi: 10.1016/j.neulet.2007.09.023 (2007).
-
(2007)
Neurosci Lett
, vol.427
, pp. 127-131
-
-
Giedraitis, V.1
-
29
-
-
79955474315
-
Endogenous amyloid-beta is necessary for hippocampal synaptic plasticity and memory
-
Puzzo, D. et al. Endogenous amyloid-beta is necessary for hippocampal synaptic plasticity and memory. Ann Neurol 69, 819-830, doi: 10.1002/ana.22313 (2011).
-
(2011)
Ann Neurol
, vol.69
, pp. 819-830
-
-
Puzzo, D.1
-
30
-
-
63449094785
-
Amyloid beta mediates memory formation
-
Garcia-Osta, A. & Alberini, C. M. Amyloid beta mediates memory formation. Learn Mem 16, 267-272, doi: 10.1101/lm.1310209 (2009).
-
(2009)
Learn Mem
, vol.16
, pp. 267-272
-
-
Garcia-Osta, A.1
Alberini, C.M.2
-
31
-
-
13644266898
-
Age-and region-dependent alterations in Abeta-degrading enzymes: Implications for Abeta-induced disorders
-
Caccamo, A., Oddo, S., Sugarman, M. C., Akbari, Y. & LaFerla, F. M. Age-and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders. Neurobiol Aging 26, 645-654, doi: 10.1016/j.neurobiolaging.2004.06.013 (2005).
-
(2005)
Neurobiol Aging
, vol.26
, pp. 645-654
-
-
Caccamo, A.1
Oddo, S.2
Sugarman, M.C.3
Akbari, Y.4
Laferla, F.M.5
-
32
-
-
0037010286
-
Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging
-
Iwata, N., Takaki, Y., Fukami, S., Tsubuki, S. & Saido, T. C. Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging. J Neurosci Res 70, 493-500, doi: 10.1002/jnr.10390 (2002).
-
(2002)
J Neurosci Res
, vol.70
, pp. 493-500
-
-
Iwata, N.1
Takaki, Y.2
Fukami, S.3
Tsubuki, S.4
Saido, T.C.5
-
33
-
-
0035846826
-
Reduced neprilysin in high plaque areas of Alzheimer brain: A possible relationship to deficient degradation of beta-amyloid peptide
-
Yasojima, K., Akiyama, H., McGeer, E. G. & McGeer, P. L. Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide. Neurosci Lett 297, 97-100 (2001).
-
(2001)
Neurosci Lett
, vol.297
, pp. 97-100
-
-
Yasojima, K.1
Akiyama, H.2
McGeer, E.G.3
McGeer, P.L.4
-
34
-
-
0035900189
-
Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain
-
Yasojima, K., McGeer, E. G. & McGeer, P. L. Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain. Brain Res 919, 115-121 (2001).
-
(2001)
Brain Res
, vol.919
, pp. 115-121
-
-
Yasojima, K.1
McGeer, E.G.2
McGeer, P.L.3
-
35
-
-
1842610004
-
Presynaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons
-
Ninan, I. & Arancio, O. Presynaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons. Neuron 42, 129-141 (2004).
-
(2004)
Neuron
, vol.42
, pp. 129-141
-
-
Ninan, I.1
Arancio, O.2
-
36
-
-
0026605658
-
Glutamate-induced long-term potentiation of the frequency of miniature synaptic currents in cultured hippocampal neurons
-
Malgaroli, A. & Tsien, R. W. Glutamate-induced long-term potentiation of the frequency of miniature synaptic currents in cultured hippocampal neurons. Nature 357, 134-139, doi: 10.1038/357134a0 (1992).
-
(1992)
Nature
, vol.357
, pp. 134-139
-
-
Malgaroli, A.1
Tsien, R.W.2
-
37
-
-
0029003966
-
Activity-dependent long-term enhancement of transmitter release by presynaptic 3,5-cyclic GMP in cultured hippocampal neurons
-
Arancio, O., Kandel, E. R. & Hawkins, R. D. Activity-dependent long-term enhancement of transmitter release by presynaptic 3,5-cyclic GMP in cultured hippocampal neurons. Nature 376, 74-80, doi: 10.1038/376074a0 (1995).
-
(1995)
Nature
, vol.376
, pp. 74-80
-
-
Arancio, O.1
Kandel, E.R.2
Hawkins, R.D.3
-
38
-
-
0035900399
-
Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation
-
Antonova, I. et al. Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation. Science 294, 1547-1550, doi: 10.1126/science.1066273 (2001).
-
(2001)
Science
, vol.294
, pp. 1547-1550
-
-
Antonova, I.1
-
39
-
-
0038285449
-
Synaptic plasticity and dynamic modulation of the postsynaptic membrane
-
Luscher, C., Nicoll, R. A., Malenka, R. C. & Muller, D. Synaptic plasticity and dynamic modulation of the postsynaptic membrane. Nat Neurosci 3, 545-550, doi: 10.1038/75714 (2000).
-
(2000)
Nat Neurosci
, vol.3
, pp. 545-550
-
-
Luscher, C.1
Nicoll, R.A.2
Malenka, R.C.3
Muller, D.4
-
40
-
-
0033359994
-
Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures
-
Carroll, R. C., Lissin, D. V., von Zastrow, M., Nicoll, R. A. & Malenka, R. C. Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures. Nat Neurosci 2, 454-460, doi: 10.1038/8123 (1999).
-
(1999)
Nat Neurosci
, vol.2
, pp. 454-460
-
-
Carroll, R.C.1
Lissin, D.V.2
Von Zastrow, M.3
Nicoll, R.A.4
Malenka, R.C.5
-
41
-
-
0033557634
-
Rapid activation-induced redistribution of ionotropic glutamate receptors in cultured hippocampal neurons
-
Lissin, D. V., Carroll, R. C., Nicoll, R. A., Malenka, R. C. & von Zastrow, M. Rapid, activation-induced redistribution of ionotropic glutamate receptors in cultured hippocampal neurons. J Neurosci 19, 1263-1272 (1999).
-
(1999)
J Neurosci
, vol.19
, pp. 1263-1272
-
-
Lissin, D.V.1
Carroll, R.C.2
Nicoll, R.A.3
Malenka, R.C.4
Von Zastrow, M.5
-
42
-
-
0033546052
-
Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation
-
Shi, S. H. et al. Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science 284, 1811-1816 (1999).
-
(1999)
Science
, vol.284
, pp. 1811-1816
-
-
Shi, S.H.1
-
43
-
-
0034788303
-
Transient synaptic activation of NMDA receptors leads to the insertion of native AMPA receptors at hippocampal neuronal plasma membranes
-
Pickard, L. et al. Transient synaptic activation of NMDA receptors leads to the insertion of native AMPA receptors at hippocampal neuronal plasma membranes. Neuropharmacology 41, 700-713 (2001).
-
(2001)
Neuropharmacology
, vol.41
, pp. 700-713
-
-
Pickard, L.1
-
44
-
-
0035132869
-
Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons
-
Lu, W. et al. Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons. Neuron 29, 243-254 (2001).
-
(2001)
Neuron
, vol.29
, pp. 243-254
-
-
Lu, W.1
-
45
-
-
0038387873
-
Conserved microtubule-actin interactions in cell movement and morphogenesis
-
Rodriguez, O. C. et al. Conserved microtubule-actin interactions in cell movement and morphogenesis. Nat Cell Biol 5, 599-609, doi: 10.1038/ncb0703-599 (2003).
-
(2003)
Nat Cell Biol
, vol.5
, pp. 599-609
-
-
Rodriguez, O.C.1
-
46
-
-
0029165076
-
Cytochalasins protect hippocampal neurons against amyloid peptide toxicity: Evidence that actin depolymerization suppresses Ca2+ influx
-
Furukawa, K. & Mattson, M. P. Cytochalasins Protect Hippocampal Neurons Against Amyloid Peptide Toxicity: Evidence that Actin Depolymerization Suppresses Ca2+ Influx. Journal of neurochemistry 65, 1061-1068 (1995).
-
(1995)
Journal of Neurochemistry
, vol.65
, pp. 1061-1068
-
-
Furukawa, K.1
Mattson, M.P.2
-
47
-
-
0031057892
-
Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells
-
Huot, J., Houle, F., Marceau, F. & Landry, J. Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells. Circ Res 80, 383-392 (1997).
-
(1997)
Circ Res
, vol.80
, pp. 383-392
-
-
Huot, J.1
Houle, F.2
Marceau, F.3
Landry, J.4
-
48
-
-
84927920792
-
Targeting human central nervous system protein kinases: An isoform selective p38alphaMAPK inhibitor that attenuates disease progression in Alzheimer's disease mouse models
-
Roy, S. M. et al. Targeting human central nervous system protein kinases: An isoform selective p38alphaMAPK inhibitor that attenuates disease progression in Alzheimer's disease mouse models. ACS Chem Neurosci 6, 666-680, doi: 10.1021/acschemneuro.5b00002 (2015).
-
(2015)
ACS Chem Neurosci
, vol.6
, pp. 666-680
-
-
Roy, S.M.1
-
49
-
-
84879526339
-
Development of novel in vivo chemical probes to address CNS protein kinase involvement in synaptic dysfunction
-
Watterson, D. M. et al. Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction. PLoS One 8, e66226, doi: 10.1371/journal.pone.0066226 (2013).
-
(2013)
PLoS One
, vol.8
, pp. 66226
-
-
Watterson, D.M.1
-
50
-
-
1842610852
-
Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5
-
Wang, Q., Walsh, D. M., Rowan, M. J., Selkoe, D. J. & Anwyl, R. Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5. J Neurosci 24, 3370-3378, doi: 10.1523/JNEUROSCI.1633-03.2004 (2004).
-
(2004)
J Neurosci
, vol.24
, pp. 3370-3378
-
-
Wang, Q.1
Walsh, D.M.2
Rowan, M.J.3
Selkoe, D.J.4
Anwyl, R.5
-
51
-
-
41549089757
-
Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction
-
Origlia, N. et al. Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction. J Neurosci 28, 3521-3530, doi: 10.1523/JNEUROSCI.0204-08.2008 (2008).
-
(2008)
J Neurosci
, vol.28
, pp. 3521-3530
-
-
Origlia, N.1
-
52
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee, J. C. et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372, 739-746, doi: 10.1038/372739a0 (1994).
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
-
53
-
-
0037263847
-
A role for ERK MAP kinase in physiologic temporal integration in hippocampal area CA1
-
Selcher, J. C. et al. A role for ERK MAP kinase in physiologic temporal integration in hippocampal area CA1. Learn Mem 10, 26-39, doi: 10.1101/lm.51103 (2003).
-
(2003)
Learn Mem
, vol.10
, pp. 26-39
-
-
Selcher, J.C.1
-
54
-
-
0033152333
-
The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus
-
Roberson, E. D. et al. The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus. J Neurosci 19, 4337-4348 (1999).
-
(1999)
J Neurosci
, vol.19
, pp. 4337-4348
-
-
Roberson, E.D.1
-
55
-
-
0034612215
-
Dynamic actin filaments are required for stable long-term potentiation (LTP) in area CA1 of the hippocampus
-
Krucker, T., Siggins, G. R. & Halpain, S. Dynamic actin filaments are required for stable long-term potentiation (LTP) in area CA1 of the hippocampus. Proc Natl Acad Sci USA 97, 6856-6861, doi: 10.1073/pnas.100139797 (2000).
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6856-6861
-
-
Krucker, T.1
Siggins, G.R.2
Halpain, S.3
-
56
-
-
0027476024
-
A synaptic model of memory: Long-term potentiation in the hippocampus
-
Bliss, T. V. & Collingridge, G. L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39, doi: 10.1038/361031a0 (1993).
-
(1993)
Nature
, vol.361
, pp. 31-39
-
-
Bliss, T.V.1
Collingridge, G.L.2
-
57
-
-
0026635574
-
Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning
-
Phillips, R. G. & LeDoux, J. E. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci 106, 274-285 (1992).
-
(1992)
Behav Neurosci
, vol.106
, pp. 274-285
-
-
Phillips, R.G.1
Ledoux, J.E.2
-
58
-
-
70549106846
-
Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses
-
Abramov, E. et al. Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses. Nat Neurosci 12, 1567-1576, doi: 10.1038/nn.2433 (2009).
-
(2009)
Nat Neurosci
, vol.12
, pp. 1567-1576
-
-
Abramov, E.1
-
59
-
-
78650816017
-
MicroRNA132 modulates short-term synaptic plasticity but not basal release probability in hippocampal neurons
-
Lambert, T. J., Storm, D. R. & Sullivan, J. M. MicroRNA132 modulates short-term synaptic plasticity but not basal release probability in hippocampal neurons. PLoS One 5, e15182, doi: 10.1371/journal.pone.0015182 (2010).
-
(2010)
PLoS One
, vol.5
, pp. 15182
-
-
Lambert, T.J.1
Storm, D.R.2
Sullivan, J.M.3
-
60
-
-
0036201201
-
Short-term synaptic plasticity
-
Zucker, R. S. & Regehr, W. G. Short-term synaptic plasticity. Annu Rev Physiol 64, 355-405, doi: 10.1146/annurev. physiol.64.092501.114547 (2002).
-
(2002)
Annu Rev Physiol
, vol.64
, pp. 355-405
-
-
Zucker, R.S.1
Regehr, W.G.2
-
61
-
-
0034282106
-
Neurodegenerative stimuli induce persistent ADF/cofilinactin rods that disrupt distal neurite function
-
Minamide, L. S., Striegl, A. M., Boyle, J. A., Meberg, P. J. & Bamburg, J. R. Neurodegenerative stimuli induce persistent ADF/cofilinactin rods that disrupt distal neurite function. Nature Cell Biology 2, 628-636 (2000).
-
(2000)
Nature Cell Biology
, vol.2
, pp. 628-636
-
-
Minamide, L.S.1
Striegl, A.M.2
Boyle, J.A.3
Meberg, P.J.4
Bamburg, J.R.5
-
62
-
-
0036847145
-
Amyloid peptide induces formation of actin stress fibers through p38 mitogenactivated protein kinase
-
Song, C., Perides, G., Wang, D. & Liu, Y. F.-Amyloid peptide induces formation of actin stress fibers through p38 mitogenactivated protein kinase. J Neurochem 83, 828-836, doi: 10.1046/j.1471-4159.2002.01182.x (2002).
-
(2002)
J Neurochem
, vol.83
, pp. 828-836
-
-
Song, C.1
Perides, G.2
Wang, D.3
Liu, Y.F.4
-
63
-
-
0029943208
-
Protein kinase C and F-actin are essential for stimulation of neuronal FAK tyrosine phosphorylation by G-proteins and amyloid beta protein
-
Zhang, C., Qiu, H. E., Krafft, G. A. & Klein, W. L. Protein kinase C and F-actin are essential for stimulation of neuronal FAK tyrosine phosphorylation by G-proteins and amyloid beta protein. FEBS Lett 386, 185-188 (1996).
-
(1996)
FEBS Lett
, vol.386
, pp. 185-188
-
-
Zhang, C.1
Qiu, H.E.2
Krafft, G.A.3
Klein, W.L.4
-
64
-
-
0036215321
-
Beta-Amyloid peptide induces ultrastructural changes in synaptosomes and potentiates mitochondrial dysfunction in the presence of ryanodine
-
Mungarro-Menchaca, X., Ferrera, P., Moran, J. & Arias, C. beta-Amyloid peptide induces ultrastructural changes in synaptosomes and potentiates mitochondrial dysfunction in the presence of ryanodine. J Neurosci Res 68, 89-96 (2002).
-
(2002)
J Neurosci Res
, vol.68
, pp. 89-96
-
-
Mungarro-Menchaca, X.1
Ferrera, P.2
Moran, J.3
Arias, C.4
-
65
-
-
20844456402
-
Alpha-Synuclein produces a long-lasting increase in neurotransmitter release
-
Liu, S. et al. alpha-Synuclein produces a long-lasting increase in neurotransmitter release. EMBO J 23, 4506-4516, doi: 10.1038/sj.emboj.7600451 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 4506-4516
-
-
Liu, S.1
-
66
-
-
84909606636
-
Insulin resistance in Alzheimer's disease
-
Dineley, K. T., Jahrling, J. B. & Denner, L. Insulin resistance in Alzheimer's disease. Neurobiol Dis 72 Pt A, 92-103, doi: 10.1016/j. nbd.2014.09.001 (2014).
-
(2014)
Neurobiol Dis
, vol.72
, pp. 92-103
-
-
Dineley, K.T.1
Jahrling, J.B.2
Denner, L.3
-
67
-
-
68549127183
-
Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abetarelated synaptic alterations
-
Tampellini, D. et al. Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abetarelated synaptic alterations. J Neurosci 29, 9704-9713, doi: 10.1523/JNEUROSCI.2292-09.2009 (2009).
-
(2009)
J Neurosci
, vol.29
, pp. 9704-9713
-
-
Tampellini, D.1
-
68
-
-
0024093449
-
Glutamate neurotoxicity and diseases of the nervous system
-
Choi, D. W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634 (1988).
-
(1988)
Neuron
, vol.1
, pp. 623-634
-
-
Choi, D.W.1
-
69
-
-
0028898888
-
Mechanisms of synaptic dysfunction in Alzheimer's disease
-
Masliah, E. Mechanisms of synaptic dysfunction in Alzheimer's disease. Histol Histopathol 10, 509-519 (1995).
-
(1995)
Histol Histopathol
, vol.10
, pp. 509-519
-
-
Masliah, E.1
-
70
-
-
84891072641
-
The schizophrenia susceptibility gene DTNBP1 modulates AMPAR synaptic transmission and plasticity in the hippocampus of juvenile DBA/2J mice
-
Orozco, I. J., Koppensteiner, P., Ninan, I. & Arancio, O. The schizophrenia susceptibility gene DTNBP1 modulates AMPAR synaptic transmission and plasticity in the hippocampus of juvenile DBA/2J mice. Mol Cell Neurosci 58, 76-84, doi: 10.1016/j. mcn.2013.12.003 (2014).
-
(2014)
Mol Cell Neurosci
, vol.58
, pp. 76-84
-
-
Orozco, I.J.1
Koppensteiner, P.2
Ninan, I.3
Arancio, O.4
-
71
-
-
80055114847
-
Preparation of oligomeric beta-amyloid
-
Induction of synaptic plasticity impairment on hippocampal slices
-
Fa, M. et al. Preparation of oligomeric beta-amyloid 1-42 and induction of synaptic plasticity impairment on hippocampal slices. J Vis Exp, doi: 10.3791/1884 (2010).
-
(2010)
J Vis Exp
, pp. 1-42
-
-
Fa, M.1
-
72
-
-
84914158381
-
Electrophysiological profiles of induced neurons converted directly from adult human fibroblasts indicate incomplete neuronal conversion
-
Koppensteiner, P., Boehm, S. & Arancio, O. Electrophysiological profiles of induced neurons converted directly from adult human fibroblasts indicate incomplete neuronal conversion. Cell Reprogram 16, 439-446, doi: 10.1089/cell.2014.0054 (2014).
-
(2014)
Cell Reprogram
, vol.16
, pp. 439-446
-
-
Koppensteiner, P.1
Boehm, S.2
Arancio, O.3
-
73
-
-
22544485048
-
Amyloid-beta peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity
-
Puzzo, D. et al. Amyloid-beta peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity. J Neurosci 25, 6887-6897, doi: 10.1523/JNEUROSCI.5291-04.2005 (2005).
-
(2005)
J Neurosci
, vol.25
, pp. 6887-6897
-
-
Puzzo, D.1
|