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Volumn 311, Issue 3, 2016, Pages G423-G430

Intestinal brush-border Na+/H+ exchanger-3 drives H+-coupled iron absorption in the mouse

Author keywords

Acidic microclimate; Hereditary hemochromatosis; Iron absorption; Iron overload; SLC11A2; SLC9A2; SLC9A3

Indexed keywords

CYTOCHROME B; CYTOCHROME B REDUCTASE 1; FERROPORTIN; HEPCIDIN; IRON; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; SODIUM PROTON EXCHANGE PROTEIN 2; SODIUM PROTON EXCHANGE PROTEIN 3; UNCLASSIFIED DRUG; DMRT1 PROTEIN; SLC9A2 PROTEIN, MOUSE; SODIUM; SODIUM PROTON EXCHANGE PROTEIN; SODIUM-HYDROGEN EXCHANGER 3; TRANSCRIPTION FACTOR;

EID: 84986216663     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00167.2016     Document Type: Article
Times cited : (26)

References (61)
  • 2
    • 21644467295 scopus 로고    scopus 로고
    • Indirect regulation of the intestinal H_-coupled amino acid transporter hPAT1 (SLC36A1)
    • Anderson CM, Thwaites DT. Indirect regulation of the intestinal H_-coupled amino acid transporter hPAT1 (SLC36A1). J Cell Physiol 204: 604-613, 2005.
    • (2005) J Cell Physiol , vol.204 , pp. 604-613
    • Anderson, C.M.1    Thwaites, D.T.2
  • 4
    • 57349091759 scopus 로고    scopus 로고
    • Why iron deficiency is important in infant development
    • Beard JL. Why iron deficiency is important in infant development. J Nutr 138: 2534-2536, 2008.
    • (2008) J Nutr , vol.138 , pp. 2534-2536
    • Beard, J.L.1
  • 5
    • 34547154545 scopus 로고    scopus 로고
    • Disorders of iron metabolism
    • edited by Kaushansky K, Beutler E, Seligsohn U, Lichtman MA, Kipps TJ, Prchal JT. New York: McGraw-Hill Medical
    • Beutler E. Disorders of iron metabolism. In: Williams Hematology, edited by Kaushansky K, Beutler E, Seligsohn U, Lichtman MA, Kipps TJ, Prchal JT. New York: McGraw-Hill Medical, 2010.
    • (2010) Williams Hematology
    • Beutler, E.1
  • 9
    • 0031426376 scopus 로고    scopus 로고
    • Functional and molecular characterization of NHE3 expression during ontogeny in rat jejunal epithelium
    • Collins JF, Xu H, Kiela PR, Zeng J, Ghishan FK. Functional and molecular characterization of NHE3 expression during ontogeny in rat jejunal epithelium. Am J Physiol Cell Physiol 273: C1937-C1946, 1997.
    • (1997) Am J Physiol Cell Physiol , vol.273 , pp. C1937-C1946
    • Collins, J.F.1    Xu, H.2    Kiela, P.R.3    Zeng, J.4    Ghishan, F.K.5
  • 17
    • 84856292277 scopus 로고    scopus 로고
    • Iron overload in human disease
    • Fleming RE, Ponka P. Iron overload in human disease. N Engl J Med 366: 348-359, 2012.
    • (2012) N Engl J Med , vol.366 , pp. 348-359
    • Fleming, R.E.1    Ponka, P.2
  • 18
    • 42549134402 scopus 로고    scopus 로고
    • AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington’s disease
    • Franich NR, Fitzsimons HL, Fong DM, Klugmann M, During MJ, Young D. AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington’s disease. Mol Ther 16: 947-956, 2008.
    • (2008) Mol Ther , vol.16 , pp. 947-956
    • Franich, N.R.1    Fitzsimons, H.L.2    Fong, D.M.3    Klugmann, M.4    During, M.J.5    Young, D.6
  • 19
    • 84885768132 scopus 로고    scopus 로고
    • Systemic iron homeostasis
    • Ganz T. Systemic iron homeostasis. Physiol Rev 93: 1721-1741, 2013.
    • (2013) Physiol Rev , vol.93 , pp. 1721-1741
    • Ganz, T.1
  • 24
    • 18244399587 scopus 로고    scopus 로고
    • Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver
    • Gunshin H, Fujiwara Y, Custodio ÁO, Direnzo C, Robine S, Andrews NC. Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver. J Clin Invest 115: 1258-1266, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 1258-1266
    • Gunshin, H.1    Fujiwara, Y.2    Custodio, Á.O.3    Direnzo, C.4    Robine, S.5    Rews, N.C.6
  • 27
    • 77955915545 scopus 로고    scopus 로고
    • Pathogenesis and management of iron toxicity in thalassemia
    • Hershko C. Pathogenesis and management of iron toxicity in thalassemia. Ann NY Acad Sci 1202: 1-9, 2010.
    • (2010) Ann NY Acad Sci , vol.1202 , pp. 1-9
    • Hershko, C.1
  • 30
    • 84865714279 scopus 로고    scopus 로고
    • Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1
    • Illing AC, Shawki A, Cunningham CL, Mackenzie B. Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1. J Biol Chem 287: 30485-30496, 2012.
    • (2012) J Biol Chem , vol.287
    • Illing, A.C.1    Shawki, A.2    Cunningham, C.L.3    Mackenzie, B.4
  • 35
    • 0020613211 scopus 로고
    • Determination of acid surface pH in vivo in rat proximal jejunum
    • Lucas M. Determination of acid surface pH in vivo in rat proximal jejunum. Gut 24: 734-739, 1983.
    • (1983) Gut , vol.24 , pp. 734-739
    • Lucas, M.1
  • 36
    • 0037608596 scopus 로고    scopus 로고
    • Selected techniques in membrane transport
    • edited by Van Winkle LJ. San Diego, CA: Academic
    • Mackenzie B. Selected techniques in membrane transport. In: Biomembrane Transport, edited by Van Winkle LJ. San Diego, CA: Academic, 1999.
    • (1999) Biomembrane Transport
    • Mackenzie, B.1
  • 38
    • 34147189116 scopus 로고    scopus 로고
    • Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1)
    • Mackenzie B, Takanaga H, Hubert N, Rolfs A, Hediger MA. Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1). Biochem J 403: 59-69, 2007.
    • (2007) Biochem J , vol.403 , pp. 59-69
    • Mackenzie, B.1    Takanaga, H.2    Hubert, N.3    Rolfs, A.4    Hediger, M.A.5
  • 41
    • 0023747201 scopus 로고
    • The effect of Escherichia coli STa enterotoxin and other secretagogues on mucosal surface pH of rat small intestine in vivo
    • McEwan GT, Daniel H, Fett C, Burgess MN, Lucas ML. The effect of Escherichia coli STa enterotoxin and other secretagogues on mucosal surface pH of rat small intestine in vivo. Proc R Soc Lond B Biol Sci 234: 219-237, 1988.
    • (1988) Proc R Soc Lond B Biol Sci , vol.234 , pp. 219-237
    • McEwan, G.T.1    Daniel, H.2    Fett, C.3    Burgess, M.N.4    Lucas, M.L.5
  • 42
    • 0025354114 scopus 로고
    • A combined TDDA-PVC pH and reference electrode for use in the upper small intestine
    • McEwan GT, Lucas ML, Mathan VI. A combined TDDA-PVC pH and reference electrode for use in the upper small intestine. J Med Eng Tech 14: 16-20, 1990.
    • (1990) J Med Eng Tech , vol.14 , pp. 16-20
    • McEwan, G.T.1    Lucas, M.L.2    Mathan, V.I.3
  • 47
    • 0026806528 scopus 로고
    • Molecular cloning of putative members of the Na/H exchanger gene family: CDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins
    • Orlowski J, Kandasamy RA, Shull GE. Molecular cloning of putative members of the Na/H exchanger gene family: cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins. J Biol Chem 267: 9331-9339, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 9331-9339
    • Orlowski, J.1    Kandasamy, R.A.2    Shull, G.E.3
  • 50
    • 0022512262 scopus 로고
    • Intestinal surface acid microclimate in vitro and in vivo in the rat
    • Said HM, Blair JA, Lucas ML, Hilburn ME. Intestinal surface acid microclimate in vitro and in vivo in the rat. J Lab Clin Med 107: 420-424, 1986.
    • (1986) J Lab Clin Med , vol.107 , pp. 420-424
    • Said, H.M.1    Blair, J.A.2    Lucas, M.L.3    Hilburn, M.E.4
  • 56
    • 34347379290 scopus 로고    scopus 로고
    • +-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine
    • +-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine. Exp Physiol 92: 603-619, 2007.
    • (2007) Exp Physiol , vol.92 , pp. 603-619
    • Thwaites, D.T.1    Erson, C.M.2
  • 58
    • 0342978587 scopus 로고
    • Tissue iron stores
    • edited by Cook JD. New York: Churchill Livingstone
    • Torrance JD, Bothwell TH. Tissue iron stores. In: Iron, edited by Cook JD. New York: Churchill Livingstone, 1980.
    • (1980) In: Iron
    • Torrance, J.D.1    Bothwell, T.H.2
  • 60
    • 21744432667 scopus 로고    scopus 로고
    • Subcloning, localization, and expression of the rat intestinal sodium-hydrogen exchanger isoform 8
    • Xu H, Chen R, Ghishan FK. Subcloning, localization, and expression of the rat intestinal sodium-hydrogen exchanger isoform 8. Am J Physiol Gastrointest Liver Physiol 289: G36-G41, 2005.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289 , pp. G36-G41
    • Xu, H.1    Chen, R.2    Ghishan, F.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.