Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice

Nature Communications

Volumn 7, Issue , 2016, Pages

  Kim Muller, Ja Young ^a   Fan, Jason ^a,b   Kim, Young Jung R ^b   Lee, Seung Ah ^a   Ishida, Emi ^a   Blaner, William S ^a   Accili, Domenico ^a  

^a Department of Medicine   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 1A3; BIOLOGICAL MARKER; CYTOCHROME C OXIDASE; GLUCOSE; INSULIN; NEUROGENIN 3; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTOME; UNCLASSIFIED DRUG; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; RETINAL DEHYDROGENASE; RETINALDEHYDE DEHYDROGENASE 3, MOUSE; RICTOR PROTEIN, MOUSE;

ALDEHYDE; BIOCHEMISTRY; CELLS AND CELL COMPONENTS; DIABETES; DIGESTIVE SYSTEM; ENZYME ACTIVITY; GLUCOSE; MITOCHONDRION; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEDIFFERENTIATION; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE COURSE; INSULIN RELEASE; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PANCREAS INSUFFICIENCY; PANCREAS ISLET BETA CELL; RNA SEQUENCE; STEM CELL; 129 MOUSE; ANIMAL; C57BL MOUSE; CELL SEPARATION; DISEASE MODEL; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; MUTATION; PATHOLOGY; SECRETION (PROCESS); SEQUENCE ANALYSIS; TUMOR CELL LINE;

MUS;

ANIMALS; BIOMARKERS; CELL DEDIFFERENTIATION; CELL LINE, TUMOR; CELL SEPARATION; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MUTATION; OXIDATIVE PHOSPHORYLATION; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR PROTEIN; RETINAL DEHYDROGENASE; SEQUENCE ANALYSIS, RNA;

EID: 84984865375     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12631     Document Type: Article

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