Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion

Biochemical and Biophysical Research Communications

Volumn 450, Issue 1, 2014, Pages 318-323

  Tang, Nie ^a   Matsuzaka, Takashi ^a   Suzuki, Marii ^a   Nakano, Yuta ^a   Zao, Hui ^a   Yokoo, Tomotaka ^b   Suzuki Kemuriyama, Noriko ^a   Kuba, Motoko ^a   Okajima, Yuka ^a   Takeuchi, Yoshinori ^a   Kobayashi, Kazuto ^a   Iwasaki, Hitoshi ^a   Yatoh, Shigeru ^a   Takahashi, Akimitsu ^a   Suzuki, Hiroaki ^a   Sone, Hirohito ^c   Shimada, Masako ^a   Nakagawa, Yoshimi ^a   Yahagi, Naoya ^a   Yamada, Nobuhiro ^a   Shimano, Hitoshi ^a   more..

^a UNIVERSITY OF TSUKUBA   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

Author keywords

Fatty acid; Insulin; Islet; Obesity; Type 2 diabetes; cell

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ELONGATION OF VERY LONG CHAIN FATTY ACID 6 PROTEIN; FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 2; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; MICROSOME ENZYME; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; SUCROSE; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; CYTOARCHITECTURE; DOWN REGULATION; HYPERINSULINEMIA; HYPERTROPHY; INSULIN RELEASE; INSULIN RESISTANCE; LIPID COMPOSITION; LIPID DIET; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SUGAR INTAKE; WILD TYPE;

MUS;

FATTY ACID; INSULIN; ISLET; OBESITY; TYPE 2 DIABETES; Β-CELL;

ACETYLTRANSFERASES; ANIMALS; CELLS, CULTURED; DIETARY FATS; FEMALE; INSULIN; INSULIN RESISTANCE; ISLETS OF LANGERHANS; MALE; MICE; MICE, KNOCKOUT; OBESITY; ORGAN SPECIFICITY; TISSUE DISTRIBUTION;

EID: 84904735278     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.05.113     Document Type: Article

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