The epigenome in Alzheimer’s disease: current state and approaches for a new path to gene discovery and understanding disease mechanism

Acta Neuropathologica

Volumn 132, Issue 4, 2016, Pages 503-514

  Klein, Hans Ulrich ^a,b,c   Bennett, David A ^d   De Jager, Philip L ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aging; Alzheimer s disease; Chromatin; DNA methylation; Epigenomics; Histone

Indexed keywords

HISTONE; HISTONE DEACETYLASE; UNTRANSLATED RNA;

AGING; ALZHEIMER DISEASE; CHROMATIN; COVALENT BOND; DNA METHYLATION; ENZYME ACTIVITY; EPIGENETICS; GENETIC ASSOCIATION STUDY; GENETIC RISK; GENETIC VARIABILITY; GENOME ANALYSIS; HISTONE MODIFICATION; HUMAN; PATHOGENESIS; PRIORITY JOURNAL; REPRODUCIBILITY; REVIEW; ANIMAL; BRAIN; GENETIC EPIGENESIS; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; PATHOLOGY; PROCEDURES; PROTEIN PROCESSING;

ALZHEIMER DISEASE; ANIMALS; BRAIN; EPIGENESIS, GENETIC; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84984653344     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-016-1612-7     Document Type: Review

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