Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo

Gut

Volumn 63, Issue 5, 2014, Pages 808-817

  Mroz, Magdalena S ^a   Keating, Niamh ^a   Ward, Joseph B ^a   Sarker, Rafiquel ^b   Amu, Silvie ^c   Aviello, Gabriella ^c   Donowitz, Mark ^b   Fallon, Padraic G ^c   Keely, Stephen J ^a  

^a BEAUMONT HOSPITAL   (Ireland)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM ION; CHLORINE; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIARRHEAL ACTIVITY; ARTICLE; BIOTINYLATION; CELL FUNCTION; CELL SURFACE; CELLULAR SECRETION; CONTROLLED STUDY; DIARRHEA; DRUG ACTIVATION; DRUG EFFICACY; DRUG TARGETING; ELECTROLYTE TRANSPORT; ENZYME ACTIVITY; ENZYME INHIBITION; EX VIVO STUDY; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; INTESTINE EPITHELIUM CELL; INTESTINE FLUID; ION TRANSPORT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; VOLTAGE CLAMP TECHNIQUE;

BILE ACID; CELL BIOLOGY; DIARRHOEA; EPITHELIAL TRANSPORT; INTESTINAL ION TRANSPORT;

ANIMALS; ANTIDIARRHEALS; BLOTTING, WESTERN; CACO-2 CELLS; CELLS, CULTURED; COLON; DIARRHEA; ELECTRODIAGNOSIS; HUMANS; INTESTINAL MUCOSA; ION TRANSPORT; ISOXAZOLES; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SODIUM-HYDROGEN ANTIPORTER;

EID: 84898011280     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2013-305088     Document Type: Article

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