CFTR and GM1 "gangl-ing" up to heal thy wound. Focus on "Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair"

American Journal of Physiology - Cell Physiology

Volumn 306, Issue 9, 2014, Pages

  Domingue, Jada C ^a   Rao, Mrinalini C ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GANGLIOSIDE GM1;

CELL MIGRATION; CYSTIC FIBROSIS; EDITORIAL; HUMAN; MEMBRANE DEPOLARIZATION; OSMOSIS; PLEIOTROPY; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; WOUND HEALING IMPAIRMENT;

ANTIGENS, CD29; CELL MOVEMENT; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; G(M1) GANGLIOSIDE; HUMANS; LUNG; WOUND HEALING;

EID: 84900555120     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00075.2014     Document Type: Editorial

References (10)

1. Eisenhoffer GT, Loftus PD, Yoshigi M, Otsuna H, Chien CB, Morcos PA, Rosenblatt J. Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia. Nature 484: 546-549, 2012.
2. Gabriel SE, Brigman KN, Koller BH, Boucher RC, Stutts MJ. Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model. Science 266: 107-109, 1994.
3. Hogenauer C, Santa Ana CA, Porter JL, Millard M, Gelfand A, Rosenblatt RL, Prestidge CB, Fordtran JS. Active intestinal chloride secretion in human carriers of cystic fibrosis mutations: an evaluation of the hypothesis that heterozygotes have subnormal active intestinal chloride secretion. Am J Hum Genet 67: 1422-1427, 2000.
4. 1-integrin signaling and delayed wound repair. Am J Physiol Cell Physiol (February 5, 2014). doi:10.1152/ajpcell. 00168.2013.
5. Kirk KL. CFTR channels and wound healing. Focus on "Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair. " Am J Physiol Cell Physiol 299: C888-C890, 2010.
6. Rhim AD, Stoykova LI, Trindade AJ, Glick MC, Scanlin TF. Altered terminal glycosylation and the pathophysiology of CF lung disease. J Cyst Fibros 3, Suppl 2: 95-96, 2004.
7. Schiller KR, Maniak PJ, O'Grady SM. Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair. Am J Physiol Cell Physiol 299: C912-C921, 2010.
8. Sun YH, Reid B, Fontaine JH, Miller LA, Hyde DM, Mogilner A, Zhao M. Airway epithelial wounds in rhesus monkey generate ionic currents that guide cell migration to promote healing. J Appl Physiol 111: 1031-1041, 2011.
9. Tang BL, Gee HY, Lee MG. The cystic fibrosis transmembrane conductance regulator's expanding SNARE interactome. Traffic 12: 364-371, 2011.
10. Wernick NL, Chinnapen DJ, Cho JA, Lencer WI. Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum. Toxins (Basel) 2: 310-325, 2010.