메뉴 건너뛰기




Volumn 311, Issue 2, 2016, Pages H404-H414

Intracrine angiotensin ii functions originate from noncanonical pathways in the human heart

Author keywords

Angiotensin converting enzyme inhibitors; Angiotensin (1 12); Heart chymase; Heart failure; Hypertension

Indexed keywords

ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSINOGEN; ANGIOTENSIN-(1-12), HUMAN; CHYMASE; PEPTIDE FRAGMENT;

EID: 84983650232     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00219.2016     Document Type: Article
Times cited : (51)

References (160)
  • 1
    • 84869129079 scopus 로고    scopus 로고
    • Subcellular characteristics of functional intracellular renin-angiotensin systems
    • Abadir PM, Walston JD, Carey RM. Subcellular characteristics of functional intracellular renin-angiotensin systems. Peptides 38: 437-445, 2012.
    • (2012) Peptides , vol.38 , pp. 437-445
    • Abadir, P.M.1    Walston, J.D.2    Carey, R.M.3
  • 2
    • 83255175529 scopus 로고    scopus 로고
    • Chymase-dependent generation of angiotensin II from angiotensin- (1-12) in human atrial tissue
    • Ahmad S, Simmons T, Varagic J, Moniwa N, Chappell MC, Ferrario CM. Chymase-dependent generation of angiotensin II from angiotensin- (1-12) in human atrial tissue. PLoS One 6: e28501, 2011.
    • (2011) Plos One , vol.6
    • Ahmad, S.1    Simmons, T.2    Varagic, J.3    Moniwa, N.4    Chappell, M.C.5    Ferrario, C.M.6
  • 4
    • 79251592234 scopus 로고    scopus 로고
    • Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes
    • Ahmad S, Varagic J, Westwood BM, Chappell MC, Ferrario CM. Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes. PLoS One 6: e15759, 2011.
    • (2011) Plos One , vol.6
    • Ahmad, S.1    Varagic, J.2    Westwood, B.M.3    Chappell, M.C.4    Ferrario, C.M.5
  • 6
    • 79955069043 scopus 로고    scopus 로고
    • The hypothalamic arcuate nucleus: A new site of cardiovascular action of angiotensin-(1-12) and angiotensin II
    • Arakawa H, Chitravanshi VC, Sapru HN. The hypothalamic arcuate nucleus: a new site of cardiovascular action of angiotensin-(1-12) and angiotensin II. Am J Physiol Heart Circ Physiol 300: H951-H960, 2011.
    • (2011) Am J Physiol Heart Circ Physiol , vol.300 , pp. H951-H960
    • Arakawa, H.1    Chitravanshi, V.C.2    Sapru, H.N.3
  • 7
    • 84872178864 scopus 로고    scopus 로고
    • Angiotensin-(1-12) in the rostral ventrolateral medullary pressor area of the rat elicits sympathoexcitatory responses
    • Arakawa H, Kawabe K, Sapru HN. Angiotensin-(1-12) in the rostral ventrolateral medullary pressor area of the rat elicits sympathoexcitatory responses. Exp Physiol 98: 94-108, 2013.
    • (2013) Exp Physiol , vol.98 , pp. 94-108
    • Arakawa, H.1    Kawabe, K.2    Sapru, H.N.3
  • 8
    • 0033770425 scopus 로고    scopus 로고
    • Hypothesis regarding the pathophysiological role of alternative pathways of angiotensin II formation in atherosclerosis
    • Arakawa K, Urata H. Hypothesis regarding the pathophysiological role of alternative pathways of angiotensin II formation in atherosclerosis. Hypertension 36: 638-641, 2000.
    • (2000) Hypertension , vol.36 , pp. 638-641
    • Arakawa, K.1    Urata, H.2
  • 9
    • 77956671617 scopus 로고    scopus 로고
    • Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus
    • Arnold AC, Isa K, Shaltout HA, Nautiyal M, Ferrario CM, Chappell MC, Diz DI. Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus. Am J Physiol Heart Circ Physiol 299: H763-H771, 2010.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , pp. H763-H771
    • Arnold, A.C.1    Isa, K.2    Shaltout, H.A.3    Nautiyal, M.4    Ferrario, C.M.5    Chappell, M.C.6    Diz, D.I.7
  • 11
    • 33751094865 scopus 로고    scopus 로고
    • Intracellular angiotensin II induces cell proliferation independent of AT1 receptor
    • Baker KM, Kumar R. Intracellular angiotensin II induces cell proliferation independent of AT1 receptor. Am J Physiol Cell Physiol 291: C995-C1001, 2006.
    • (2006) Am J Physiol Cell Physiol , vol.291 , pp. CC995-C1001
    • Baker, K.M.1    Kumar, R.2
  • 12
    • 72949090178 scopus 로고    scopus 로고
    • Systematic review: Comparative effectiveness of angiotensin-converting enzyme inhibitors or angiotensin II-receptor blockers for ischemic heart disease
    • Baker WL, Coleman CI, Kluger J, Reinhart KM, Talati R, Quercia R, Phung OJ, White CM. Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors or angiotensin II-receptor blockers for ischemic heart disease. Ann Intern Med 151: 861-871, 2009.
    • (2009) Ann Intern Med , vol.151 , pp. 861-871
    • Baker, W.L.1    Coleman, C.I.2    Kluger, J.3    Reinhart, K.M.4    Talati, R.5    Quercia, R.6    Phung, O.J.7    White, C.M.8
  • 13
    • 0030662137 scopus 로고    scopus 로고
    • Dell=Italia LJ. Angiotensin II formation from ACE and chymase in human and animal hearts: Methods and species considerations
    • Balcells E, Meng QC, Johnson WH Jr, Oparil S, Dell=Italia LJ. Angiotensin II formation from ACE and chymase in human and animal hearts: methods and species considerations. Am J Physiol Heart Circ Physiol 273: H1769-H1774, 1997.
    • (1997) Am J Physiol Heart Circ Physiol , vol.273 , pp. H1769-H1774
    • Balcells, E.1    Meng, Q.C.2    Johnson, W.H.3    Oparil, S.4
  • 14
    • 79961097301 scopus 로고    scopus 로고
    • Angiotensinconverting enzyme inhibition augments the expression of rat elastase-2, an angiotensin II-forming enzyme
    • Becari C, Teixeira FR, Oliveira EB, Salgado MC. Angiotensinconverting enzyme inhibition augments the expression of rat elastase-2, an angiotensin II-forming enzyme. Am J Physiol Heart Circ Physiol 301: H565-H570, 2011.
    • (2011) Am J Physiol Heart Circ Physiol , vol.301 , pp. H565-H570
    • Becari, C.1    Teixeira, F.R.2    Oliveira, E.B.3    Salgado, M.C.4
  • 15
    • 0034573872 scopus 로고    scopus 로고
    • Angiotensin II-generating enzymes
    • Belova LA. Angiotensin II-generating enzymes. Biochemistry (Mosc) 65: 1337-1345, 2000.
    • (2000) Biochemistry (Mosc) , vol.65 , pp. 1337-1345
    • Belova, L.A.1
  • 16
    • 0026573210 scopus 로고
    • Immunohistochemical localization of rat submandibular gland esterase B (Homologous to the RSKG-7 kallikrein gene) in relation to other serine proteases of the kallikrein family
    • Berg T, Wassdal I, Sletten K. Immunohistochemical localization of rat submandibular gland esterase B (homologous to the RSKG-7 kallikrein gene) in relation to other serine proteases of the kallikrein family. J Histochem Cytochem 40: 83-92, 1992.
    • (1992) J Histochem Cytochem , vol.40 , pp. 83-92
    • Berg, T.1    Wassdal, I.2    Sletten, K.3
  • 18
    • 84947201468 scopus 로고    scopus 로고
    • Impact of renin-angiotensin system inhibitors on mortality and major cardiovascular endpoints in hypertension: A number-neededto- treat analysis
    • Brugts JJ, van VL, Akkerhuis M, Bertrand M, Fox K, Mourad JJ, Boersma E. Impact of renin-angiotensin system inhibitors on mortality and major cardiovascular endpoints in hypertension: a number-neededto- treat analysis. Int J Cardiol 181: 425-429, 2015.
    • (2015) Int J Cardiol , vol.181 , pp. 425-429
    • Brugts, J.J.1    Van, V.L.2    Akkerhuis, M.3    Bertrand, M.4    Fox, K.5    Mourad, J.J.6    Boersma, E.7
  • 20
    • 0021635502 scopus 로고
    • Action of proteolytic enzymes on lipotropins and endorphins: Biosynthesis, biotransformation and fate
    • Burbach JP. Action of proteolytic enzymes on lipotropins and endorphins: biosynthesis, biotransformation and fate. Pharmacol Ther 24: 321-354, 1984.
    • (1984) Pharmacol Ther , vol.24 , pp. 321-354
    • Burbach, J.P.1
  • 21
    • 84857820252 scopus 로고    scopus 로고
    • Functional intracellular renin-angiotensin systems: Potential for pathophysiology of disease
    • Carey RM. Functional intracellular renin-angiotensin systems: potential for pathophysiology of disease. Am J Physiol Regul Integr Comp Physiol 302: R479-R481, 2012.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , pp. R479-R481
    • Carey, R.M.1
  • 22
    • 34248140140 scopus 로고    scopus 로고
    • Mast cell tryptases and chymases in inflammation and host defense
    • Caughey GH. Mast cell tryptases and chymases in inflammation and host defense. Immunol Rev 217: 141-154, 2007.
    • (2007) Immunol Rev , vol.217 , pp. 141-154
    • Caughey, G.H.1
  • 26
    • 84954503383 scopus 로고    scopus 로고
    • Biochemical evaluation of the renin-angiotensin system: The good, bad, and absolute?
    • Chappell MC. Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute? Am J Physiol Heart Circ Physiol 310: H137-H152, 2016.
    • (2016) Am J Physiol Heart Circ Physiol , vol.310 , pp. H137-H152
    • Chappell, M.C.1
  • 28
    • 84865549994 scopus 로고    scopus 로고
    • Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II
    • Chitravanshi VC, Proddutur A, Sapru HN. Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II. Exp Physiol 97: 1001-1017, 2012.
    • (2012) Exp Physiol , vol.97 , pp. 1001-1017
    • Chitravanshi, V.C.1    Proddutur, A.2    Sapru, H.N.3
  • 29
    • 78651318031 scopus 로고    scopus 로고
    • Cardiovascular responses elicited by a new endogenous angiotensin in the nucleus tractus solitarius of the rat
    • Chitravanshi VC, Sapru HN. Cardiovascular responses elicited by a new endogenous angiotensin in the nucleus tractus solitarius of the rat. Am J Physiol Heart Circ Physiol 300: H230-H240, 2011.
    • (2011) Am J Physiol Heart Circ Physiol , vol.300 , pp. H230-H240
    • Chitravanshi, V.C.1    Sapru, H.N.2
  • 30
    • 84857888402 scopus 로고    scopus 로고
    • Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model
    • Cook JL, Re RN. Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model. Am J Physiol Regul Integr Comp Physiol 302: R482-R493, 2012.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , pp. R482-R493
    • Cook, J.L.1    Re, R.N.2
  • 31
    • 0035824901 scopus 로고    scopus 로고
    • Vitro evidence for an intracellular site of angiotensin action
    • Cook JL, Zhang Z, Re RN. In vitro evidence for an intracellular site of angiotensin action. Circ Res 89: 1138-1146, 2001.
    • (2001) Circ Res , vol.89 , pp. 1138-1146
    • Cook, J.L.1    Zhang, Z.2    Re, R.N.3
  • 33
    • 0029054506 scopus 로고
    • Influence of intracellular renin on heart cell communication
    • De Mello WC. Influence of intracellular renin on heart cell communication. Hypertension 25: 1172-1177, 1995.
    • (1995) Hypertension , vol.25 , pp. 1172-1177
    • De Mello, W.C.1
  • 34
    • 0032407402 scopus 로고    scopus 로고
    • Intracellular angiotensin II regulates the inward calcium current in cardiac myocytes
    • De Mello WC. Intracellular angiotensin II regulates the inward calcium current in cardiac myocytes. Hypertension 32: 976-982, 1998.
    • (1998) Hypertension , vol.32 , pp. 976-982
    • De Mello, W.C.1
  • 35
    • 14844345007 scopus 로고    scopus 로고
    • Angiotensin (1-7) re-establishes impulse conduction in cardiac muscle during ischaemia-reperfusion. The role of the sodium pump
    • De Mello WC. Angiotensin (1-7) re-establishes impulse conduction in cardiac muscle during ischaemia-reperfusion. The role of the sodium pump. J Renin Angiotensin Aldosterone Syst 5: 203-208, 2004.
    • (2004) J Renin Angiotensin Aldosterone Syst , vol.5 , pp. 203-208
    • De Mello, W.C.1
  • 36
    • 84962278678 scopus 로고    scopus 로고
    • Intracellular angiotensin II as a regulator of muscle tone in vascular resistance vessels. Pathophysiological implications
    • De Mello WC. Intracellular angiotensin II as a regulator of muscle tone in vascular resistance vessels. Pathophysiological implications. Peptides 78: 87-90, 2016.
    • (2016) Peptides , vol.78 , pp. 87-90
    • De Mello, W.C.1
  • 37
    • 0343627693 scopus 로고    scopus 로고
    • Angiotensin II and the heart: On the intracrine renin-angiotensin system
    • De Mello WC, Danser AH. Angiotensin II and the heart: on the intracrine renin-angiotensin system. Hypertension 35: 1183-1188, 2000.
    • (2000) Hypertension , vol.35 , pp. 1183-1188
    • De Mello, W.C.1    Danser, A.H.2
  • 38
    • 80051545369 scopus 로고    scopus 로고
    • On the local cardiac renin angiotensin system. Basic and clinical implications
    • De Mello WC, Frohlich ED. On the local cardiac renin angiotensin system. Basic and clinical implications. Peptides 32: 1774-1779, 2011.
    • (2011) Peptides , vol.32 , pp. 1774-1779
    • De Mello, W.C.1    Frohlich, E.D.2
  • 39
    • 0036023644 scopus 로고    scopus 로고
    • Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases
    • Dell’Italia LJ, Husain A. Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases. Curr Opin Cardiol 17: 374-379, 2002.
    • (2002) Curr Opin Cardiol , vol.17 , pp. 374-379
    • Dell’Italia, L.J.1    Husain, A.2
  • 40
    • 0030838414 scopus 로고    scopus 로고
    • Compartmentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spaces
    • Dell’Italia LJ, Meng QC, Balcells E, Wei CC, Palmer R, Hageman GR, Durand J, Hankes GH, Oparil S. Compartmentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spaces. J Clin Invest 100: 253-258, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 253-258
    • Dell’Italia, L.J.1    Meng, Q.C.2    Balcells, E.3    Wei, C.C.4    Palmer, R.5    Hageman, G.R.6    Durand, J.7    Hankes, G.H.8    Oparil, S.9
  • 41
    • 0034725654 scopus 로고    scopus 로고
    • The cardiac renin-angiotensin system: Novel signaling mechanisms related to cardiac growth and function
    • Dostal DE. The cardiac renin-angiotensin system: novel signaling mechanisms related to cardiac growth and function. Regul Pept 91: 1-11, 2000.
    • (2000) Regul Pept , vol.91 , pp. 1-11
    • Dostal, D.E.1
  • 42
    • 0019248458 scopus 로고
    • Identification of renin and renin-like enzymes in rat brain by a renin-specific antibody
    • Dzau VJ, Brenner A, Emmett N, Haber E. Identification of renin and renin-like enzymes in rat brain by a renin-specific antibody. Clin Sci (Lond) 59, Suppl 6: 45s-47s, 1980.
    • (1980) Clin Sci (Lond) , vol.59 , pp. 45s-47s
    • Dzau, V.J.1    Brenner, A.2    Emmett, N.3    Haber, E.4
  • 43
    • 84863230547 scopus 로고    scopus 로고
    • Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney
    • Ellis B, Li XC, Miguel-Qin E, Gu V, Zhuo JL. Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney. Am J Physiol Regul Integr Comp Physiol 302: R494-R509, 2012.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , pp. R494-R509
    • Ellis, B.1    Li, X.C.2    Miguel-Qin, E.3    Gu, V.4    Zhuo, J.L.5
  • 44
    • 84940757237 scopus 로고    scopus 로고
    • ANG II-independent prorenin/(Pro)renin receptor signaling pathways in the central nervous system
    • Feng Y. ANG II-independent prorenin/(pro)renin receptor signaling pathways in the central nervous system. Am J Physiol Heart Circ Physiol 309: H731-H733, 2015.
    • (2015) Am J Physiol Heart Circ Physiol , vol.309 , pp. H731-H733
    • Feng, Y.1
  • 50
  • 53
    • 0023231293 scopus 로고
    • Kinetic studies on the inhibitions of mast cell chymase by natural serine protease inhibitors: Indications for potential biological functions of these inhibitors
    • Fukusen N, Kato Y, Kido H, Katunuma N. Kinetic studies on the inhibitions of mast cell chymase by natural serine protease inhibitors: indications for potential biological functions of these inhibitors. Biochem Med Metab Biol 38: 165-169, 1987.
    • (1987) Biochem Med Metab Biol , vol.38 , pp. 165-169
    • Fukusen, N.1    Kato, Y.2    Kido, H.3    Katunuma, N.4
  • 62
    • 0037967318 scopus 로고    scopus 로고
    • Chymase is upregulated in diabetic nephropathy: Implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease
    • Huang XR, Chen WY, Truong LD, Lan HY. Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease. J Am Soc Nephrol 14: 1738-1747, 2003.
    • (2003) J am Soc Nephrol , vol.14 , pp. 1738-1747
    • Huang, X.R.1    Chen, W.Y.2    Truong, L.D.3    Lan, H.Y.4
  • 63
    • 84940733285 scopus 로고    scopus 로고
    • Activation of the (Pro)renin receptor in the paraventricular nucleus increases sympathetic outflow in anesthetized rats
    • Huber MJ, Basu R, Cecchettini C, Cuadra AE, Chen QH, Shan Z. Activation of the (pro)renin receptor in the paraventricular nucleus increases sympathetic outflow in anesthetized rats. Am J Physiol Heart Circ Physiol 309: H880-H887, 2015.
    • (2015) Am J Physiol Heart Circ Physiol , vol.309 , pp. H880-H887
    • Huber, M.J.1    Basu, R.2    Cecchettini, C.3    Cuadra, A.E.4    Chen, Q.H.5    Shan, Z.6
  • 64
    • 0027442410 scopus 로고
    • The chymase-angiotensin system in humans
    • Husain A. The chymase-angiotensin system in humans. J Hypertens 11: 1155-1159, 1993.
    • (1993) J Hypertens , vol.11 , pp. 1155-1159
    • Husain, A.1
  • 65
    • 0021267290 scopus 로고
    • Biochemical and immunological properties of dog brain isorenin
    • Husain A, Smeby RR, Wilk D, Dzau VJ, Bumpus FM. Biochemical and immunological properties of dog brain isorenin. Endocrinology 114: 2210-2215, 1984.
    • (1984) Endocrinology , vol.114 , pp. 2210-2215
    • Husain, A.1    Smeby, R.R.2    Wilk, D.3    Dzau, V.J.4    Bumpus, F.M.5
  • 71
    • 84893391428 scopus 로고    scopus 로고
    • Cardiovascular effect of angiotensin-(1-12) in the caudal ventrolateral medullary depressor area of the rat
    • Kawabe T, Kawabe K, Sapru HN. Cardiovascular effect of angiotensin-(1-12) in the caudal ventrolateral medullary depressor area of the rat. Am J Physiol Heart Circ Physiol 306: H438-H449, 2014.
    • (2014) Am J Physiol Heart Circ Physiol , vol.306 , pp. H438-H449
    • Kawabe, T.1    Kawabe, K.2    Sapru, H.N.3
  • 72
    • 27644585370 scopus 로고    scopus 로고
    • Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients
    • Keidar S, Gamliel-Lazarovich A, Kaplan M, Pavlotzky E, Hamoud S, Hayek T, Karry R, Abassi Z. Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients. Circ Res 97: 946-953, 2005.
    • (2005) Circ Res , vol.97 , pp. 946-953
    • Keidar, S.1    Gamliel-Lazarovich, A.2    Kaplan, M.3    Pavlotzky, E.4    Hamoud, S.5    Hayek, T.6    Karry, R.7    Abassi, Z.8
  • 73
    • 0022503785 scopus 로고
    • Purification and characterization of a serine protease (Esterase B) from rat submandibular glands
    • Khullar M, Scicli G, Carretero OA, Scicli AG. Purification and characterization of a serine protease (esterase B) from rat submandibular glands. Biochemistry 25: 1851-1857, 1986.
    • (1986) Biochemistry , vol.25 , pp. 1851-1857
    • Khullar, M.1    Scicli, G.2    Carretero, O.A.3    Scicli, A.G.4
  • 74
    • 0024237214 scopus 로고
    • Kunitz-type protease inhibitor found in rat mast cells. Purification, properties, and amino acid sequence
    • Kido H, Yokogoshi Y, Katunuma N. Kunitz-type protease inhibitor found in rat mast cells. Purification, properties, and amino acid sequence. J Biol Chem 263: 18104-18107, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 18104-18107
    • Kido, H.1    Yokogoshi, Y.2    Katunuma, N.3
  • 75
    • 21244471960 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and diabetes with angiotensin-receptor blockers in hypertension: LIFE, SCOPE, and VALUE
    • Kjeldsen SE, Westheim AS, Os I. Prevention of cardiovascular events and diabetes with angiotensin-receptor blockers in hypertension: LIFE, SCOPE, and VALUE. Curr Hypertens Rep 7: 155-157, 2005.
    • (2005) Curr Hypertens Rep , vol.7 , pp. 155-157
    • Kjeldsen, S.E.1    Westheim, A.S.2    Os, I.3
  • 76
    • 33645746010 scopus 로고    scopus 로고
    • Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications
    • Koka V, Wang W, Huang XR, Kim-Mitsuyama S, Truong LD, Lan HY. Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications. Circulation 113: 1353-1360, 2006.
    • (2006) Circulation , vol.113 , pp. 1353-1360
    • Koka, V.1    Wang, W.2    Huang, X.R.3    Kim-Mitsuyama, S.4    Truong, L.D.5    Lan, H.Y.6
  • 78
    • 58149247946 scopus 로고    scopus 로고
    • Diversity of pathways for intracellular angiotensin II synthesis
    • Kumar R, Boim MA. Diversity of pathways for intracellular angiotensin II synthesis. Curr Opin Nephrol Hypertens 18: 33-39, 2009.
    • (2009) Curr Opin Nephrol Hypertens , vol.18 , pp. 33-39
    • Kumar, R.1    Boim, M.A.2
  • 82
    • 0037324287 scopus 로고    scopus 로고
    • Mast cell chymase induces smooth muscle cell apoptosis by a mechanism involving fibronectin degradation and disruption of focal adhesions
    • Leskinen MJ, Lindstedt KA, Wang Y, Kovanen PT. Mast cell chymase induces smooth muscle cell apoptosis by a mechanism involving fibronectin degradation and disruption of focal adhesions. Arterioscler Thromb Vasc Biol 23: 238-243, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 238-243
    • Leskinen, M.J.1    Lindstedt, K.A.2    Wang, Y.3    Kovanen, P.T.4
  • 83
    • 84959328564 scopus 로고    scopus 로고
    • The autocrine role of tryptase in pressure overload-induced mast cell activation, chymase release and cardiac fibrosis
    • Li J, Jubair S, Levick SP, Janicki JS. The autocrine role of tryptase in pressure overload-induced mast cell activation, chymase release and cardiac fibrosis. IJC Metab Endocr 10: 16-23, 2016.
    • (2016) IJC Metab Endocr , vol.10 , pp. 16-23
    • Li, J.1    Jubair, S.2    Levick, S.P.3    Janicki, J.S.4
  • 85
    • 0025168069 scopus 로고
    • Cardiac angiotensinogen and its local activation in the isolated perfused beating heart
    • Lindpaintner K, Jin MW, Niedermaier N, Wilhelm MJ, Ganten D. Cardiac angiotensinogen and its local activation in the isolated perfused beating heart. Circ Res 67: 564-573, 1990.
    • (1990) Circ Res , vol.67 , pp. 564-573
    • Lindpaintner, K.1    Jin, M.W.2    Niedermaier, N.3    Wilhelm, M.J.4    Ganten, D.5
  • 87
    • 0037512313 scopus 로고    scopus 로고
    • Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure
    • Matsumoto T, Wada A, Tsutamoto T, Ohnishi M, Isono T, Kinoshita M. Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure. Circulation 107: 2555-2558, 2003.
    • (2003) Circulation , vol.107 , pp. 2555-2558
    • Matsumoto, T.1    Wada, A.2    Tsutamoto, T.3    Ohnishi, M.4    Isono, T.5    Kinoshita, M.6
  • 91
    • 0026040529 scopus 로고
    • Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase
    • Mizutani H, Schechter N, Lazarus G, Black RA, Kupper TS. Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. J Exp Med 174: 821-825, 1991.
    • (1991) J Exp Med , vol.174 , pp. 821-825
    • Mizutani, H.1    Schechter, N.2    Lazarus, G.3    Black, R.A.4    Kupper, T.S.5
  • 93
    • 0030293795 scopus 로고    scopus 로고
    • Angiotensinogen: Molecular biology, biochemistry and physiology
    • Morgan L, Broughton PF, Kalsheker N. Angiotensinogen: molecular biology, biochemistry and physiology. Int J Biochem Cell Biol 28: 1211-1222, 1996.
    • (1996) Int J Biochem Cell Biol , vol.28 , pp. 1211-1222
    • Morgan, L.1    Broughton, P.F.2    Kalsheker, N.3
  • 94
    • 84930288628 scopus 로고
    • Human renin protein and gene structures: Present and future targets for renin blockade in treatment of hypertension
    • Morris BJ. Human renin protein and gene structures: present and future targets for renin blockade in treatment of hypertension. J Hypertens Suppl 7: S9-S14, 1989.
    • (1989) J Hypertens Suppl , vol.7 , pp. SS9-S14
    • Morris, B.J.1
  • 96
    • 84856746787 scopus 로고    scopus 로고
    • Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system
    • Nagata S, Kato J, Kuwasako K, Asami M, Kitamura K. Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system. Hypertens Res 35: 234-238, 2012.
    • (2012) Hypertens Res , vol.35 , pp. 234-238
    • Nagata, S.1    Kato, J.2    Kuwasako, K.3    Asami, M.4    Kitamura, K.5
  • 97
    • 77951257899 scopus 로고    scopus 로고
    • Plasma and tissue levels of proangiotensin-12 and components of the renin-angiotensin system (RAS) following low- or high-salt feeding in rats
    • Nagata S, Kato J, Kuwasako K, Kitamura K. Plasma and tissue levels of proangiotensin-12 and components of the renin-angiotensin system (RAS) following low- or high-salt feeding in rats. Peptides 31: 889-892, 2010.
    • (2010) Peptides , vol.31 , pp. 889-892
    • Nagata, S.1    Kato, J.2    Kuwasako, K.3    Kitamura, K.4
  • 98
    • 33750147612 scopus 로고    scopus 로고
    • Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system
    • Nagata S, Kato J, Sasaki K, Minamino N, Eto T, Kitamura K. Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system. Biochem Biophys Res Commun 350: 1026-1031, 2006.
    • (2006) Biochem Biophys Res Commun , vol.350 , pp. 1026-1031
    • Nagata, S.1    Kato, J.2    Sasaki, K.3    Minamino, N.4    Eto, T.5    Kitamura, K.6
  • 100
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109: 1417-1427, 2002.
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.D.6
  • 101
    • 80053144553 scopus 로고    scopus 로고
    • Chymase inhibition reduces infarction and matrix metalloproteinase-9 activation and attenuates inflammation and fibrosis after acute myocardial ischemia/ reperfusion
    • Oyamada S, Bianchi C, Takai S, Chu LM, Sellke FW. Chymase inhibition reduces infarction and matrix metalloproteinase-9 activation and attenuates inflammation and fibrosis after acute myocardial ischemia/ reperfusion. J Pharmacol Exp Ther 339: 143-151, 2011.
    • (2011) J Pharmacol Exp Ther , vol.339 , pp. 143-151
    • Oyamada, S.1    Bianchi, C.2    Takai, S.3    Chu, L.M.4    Sellke, F.W.5
  • 103
    • 33745845825 scopus 로고    scopus 로고
    • Physiology of local renin-angiotensin systems
    • Paul M, Poyan MA, Kreutz R. Physiology of local renin-angiotensin systems. Physiol Rev 86: 747-803, 2006.
    • (2006) Physiol Rev , vol.86 , pp. 747-803
    • Paul, M.1    Poyan, M.A.2    Kreutz, R.3
  • 104
    • 77954663588 scopus 로고    scopus 로고
    • Mast cell proteases: Multifaceted regulators of inflammatory disease
    • Pejler G, Ronnberg E, Waern I, Wernersson S. Mast cell proteases: multifaceted regulators of inflammatory disease. Blood 115: 4981-4990, 2010.
    • (2010) Blood , vol.115 , pp. 4981-4990
    • Pejler, G.1    Ronnberg, E.2    Waern, I.3    Wernersson, S.4
  • 105
    • 84875016368 scopus 로고    scopus 로고
    • (Pro)renin receptor mediates both angiotensin II-dependent and -independent oxidative stress in neuronal cells
    • Peng H, Li W, Seth DM, Nair AR, Francis J, Feng Y. (Pro)renin receptor mediates both angiotensin II-dependent and -independent oxidative stress in neuronal cells. PLoS One 8: e58339, 2013.
    • (2013) Plos One , vol.8
    • Peng, H.1    Li, W.2    Seth, D.M.3    Nair, A.R.4    Francis, J.5    Feng, Y.6
  • 106
    • 84855767212 scopus 로고    scopus 로고
    • Carboxypeptidases A1 and A2 from the perfusate of rat mesenteric arterial bed differentially process angiotensin peptides
    • Pereira HJ, Souza LL, Costa-Neto CM, Salgado MC, Oliveira EB. Carboxypeptidases A1 and A2 from the perfusate of rat mesenteric arterial bed differentially process angiotensin peptides. Peptides 33: 67-76, 2012.
    • (2012) Peptides , vol.33 , pp. 67-76
    • Pereira, H.J.1    Souza, L.L.2    Costa-Neto, C.M.3    Salgado, M.C.4    Oliveira, E.B.5
  • 108
    • 62349100153 scopus 로고    scopus 로고
    • Cardiac chymase converts rat proAngiotensin-12 (PA12) to angiotensin II: Effects of PA12 upon cardiac haemodynamics
    • Prosser HC, Forster ME, Richards AM, Pemberton CJ. Cardiac chymase converts rat proAngiotensin-12 (PA12) to angiotensin II: effects of PA12 upon cardiac haemodynamics. Cardiovasc Res 82: 40-50, 2009.
    • (2009) Cardiovasc Res , vol.82 , pp. 40-50
    • Prosser, H.C.1    Forster, M.E.2    Richards, A.M.3    Pemberton, C.J.4
  • 109
    • 78249238801 scopus 로고    scopus 로고
    • Regional vascular response to ProAngiotensin-12 (PA12) through the rat arterial system
    • Prosser HC, Richards AM, Forster ME, Pemberton CJ. Regional vascular response to ProAngiotensin-12 (PA12) through the rat arterial system. Peptides 31: 1540-1545, 2010.
    • (2010) Peptides , vol.31 , pp. 1540-1545
    • Prosser, H.C.1    Richards, A.M.2    Forster, M.E.3    Pemberton, C.J.4
  • 110
    • 0022697108 scopus 로고
    • [“Mixed” endocrine gland cells of the duodenal epithelium in various vertebrate animals and man]
    • Puzyrev AA, Ivanova VF. [“Mixed” endocrine gland cells of the duodenal epithelium in various vertebrate animals and man]. Arkh Anat Gistol Embriol 90: 48-54, 1986.
    • (1986) Arkh Anat Gistol Embriol , vol.90 , pp. 48-54
    • Puzyrev, A.A.1    Ivanova, V.F.2
  • 111
    • 0036324175 scopus 로고    scopus 로고
    • Release and degradation of angiotensin I and angiotensin II from angiotensinogen by neutrophil serine proteinases
    • Ramaha A, Patston PA. Release and degradation of angiotensin I and angiotensin II from angiotensinogen by neutrophil serine proteinases. Arch Biochem Biophys 397: 77-83, 2002.
    • (2002) Arch Biochem Biophys , vol.397 , pp. 77-83
    • Ramaha, A.1    Patston, P.A.2
  • 112
    • 0024797786 scopus 로고
    • The cellular biology of angiotensin: Paracrine, autocrine and intracrine actions in cardiovascular tissues
    • Re RN. The cellular biology of angiotensin: paracrine, autocrine and intracrine actions in cardiovascular tissues. J Mol Cell Cardiol 21, Suppl 5: 63-69, 1989.
    • (1989) J Mol Cell Cardiol , vol.21 , pp. 63-69
    • Re, R.N.1
  • 113
    • 84940447676 scopus 로고    scopus 로고
    • A mechanism for mineralocortcoid participation in renal disease and heart failure
    • Re RN. A mechanism for mineralocortcoid participation in renal disease and heart failure. J Am Soc Hypertens 9: 586-591, 2015.
    • (2015) J am Soc Hypertens , vol.9 , pp. 586-591
    • Re, R.N.1
  • 116
    • 84856718876 scopus 로고    scopus 로고
    • Regulation of a novel angiotensin II precursor, proangiotensin-12, in the tissues by blockade of the renin-angiotensin system
    • Satou R, Kobori H. Regulation of a novel angiotensin II precursor, proangiotensin-12, in the tissues by blockade of the renin-angiotensin system. Hypertens Res 35: 153-154, 2012.
    • (2012) Hypertens Res , vol.35 , pp. 153-154
    • Satou, R.1    Kobori, H.2
  • 118
    • 34547735173 scopus 로고    scopus 로고
    • High-glucoseinduced regulation of intracellular ANG II synthesis and nuclear redistribution in cardiac myocytes
    • Singh VP, Le B, Bhat VB, Baker KM, Kumar R. High-glucoseinduced regulation of intracellular ANG II synthesis and nuclear redistribution in cardiac myocytes. Am J Physiol Heart Circ Physiol 293: H939-H948, 2007.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. H939-H948
    • Singh, V.P.1    Le, B.2    Bhat, V.B.3    Baker, K.M.4    Kumar, R.5
  • 119
    • 0000586975 scopus 로고
    • The preparation, purification, and amino acid sequence of a polypeptide renin substrate
    • Skeggs LT Jr, Kahn JR, Lentz K, Shumway NP. The preparation, purification, and amino acid sequence of a polypeptide renin substrate. J Exp Med 106: 439-453, 1957.
    • (1957) J Exp Med , vol.106 , pp. 439-453
    • Skeggs, L.T.1    Kahn, J.R.2    Lentz, K.3    Shumway, N.P.4
  • 120
    • 0028956737 scopus 로고
    • Human mast cell chymase and leukocyte elastase release latent transforming growth factor-beta 1 from the extracellular matrix of cultured human epithelial and endothelial cells
    • Taipale J, Lohi J, Saarinen J, Kovanen PT, Keski-Oja J. Human mast cell chymase and leukocyte elastase release latent transforming growth factor-beta 1 from the extracellular matrix of cultured human epithelial and endothelial cells. J Biol Chem 270: 4689-4696, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 4689-4696
    • Taipale, J.1    Lohi, J.2    Saarinen, J.3    Kovanen, P.T.4    Keski-Oja, J.5
  • 121
    • 77956199892 scopus 로고    scopus 로고
    • New approaches to blockade of the renin-angiotensin-aldosterone system: Chymase as an important target to prevent organ damage
    • Takai S, Jin D, Miyazaki M. New approaches to blockade of the renin-angiotensin-aldosterone system: chymase as an important target to prevent organ damage. J Pharmacol Sci 113: 301-309, 2010.
    • (2010) J Pharmacol Sci , vol.113 , pp. 301-309
    • Takai, S.1    Jin, D.2    Miyazaki, M.3
  • 122
    • 84859510328 scopus 로고    scopus 로고
    • Multiple mechanisms for the action of chymase inhibitors
    • Takai S, Jin D, Miyazaki M. Multiple mechanisms for the action of chymase inhibitors. J Pharmacol Sci 118: 311-316, 2012.
    • (2012) J Pharmacol Sci , vol.118 , pp. 311-316
    • Takai, S.1    Jin, D.2    Miyazaki, M.3
  • 123
    • 4644289087 scopus 로고    scopus 로고
    • Therapeutic applications of chymase inhibitors in cardiovascular diseases and fibrosis
    • Takai S, Jin D, Muramatsu M, Okamoto Y, Miyazaki M. Therapeutic applications of chymase inhibitors in cardiovascular diseases and fibrosis. Eur J Pharmacol 501: 1-8, 2004.
    • (2004) Eur J Pharmacol , vol.501 , pp. 1-8
    • Takai, S.1    Jin, D.2    Muramatsu, M.3    Okamoto, Y.4    Miyazaki, M.5
  • 125
    • 15744388309 scopus 로고    scopus 로고
    • A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2
    • Tchougounova E, Lundequist A, Fajardo I, Winberg JO, Abrink M, Pejler G. A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2. J Biol Chem 280: 9291-9296, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 9291-9296
    • Tchougounova, E.1    Lundequist, A.2    Fajardo, I.3    Winberg, J.O.4    Abrink, M.5    Pejler, G.6
  • 126
    • 0029907068 scopus 로고    scopus 로고
    • Quantitation of five forms of high molecular weight angiotensinogen from human placenta
    • Tewksbury DA. Quantitation of five forms of high molecular weight angiotensinogen from human placenta. Am J Hypertens 9: 1029-1034, 1996.
    • (1996) Am J Hypertens , vol.9 , pp. 1029-1034
    • Tewksbury, D.A.1
  • 127
    • 0020411938 scopus 로고
    • High molecular weight angiotensinogen levels in hypertensive pregnant women
    • Tewksbury DA, Dart RA. High molecular weight angiotensinogen levels in hypertensive pregnant women. Hypertension 4: 729-734, 1982.
    • (1982) Hypertension , vol.4 , pp. 729-734
    • Tewksbury, D.A.1    Dart, R.A.2
  • 128
    • 0024521689 scopus 로고
    • Immunochemical comparison of high molecular weight angiotensinogen from amniotic fluid, plasma of men, and plasma of pregnant women
    • Tewksbury DA, Tryon ES. Immunochemical comparison of high molecular weight angiotensinogen from amniotic fluid, plasma of men, and plasma of pregnant women. Am J Hypertens 2: 411-413, 1989.
    • (1989) Am J Hypertens , vol.2 , pp. 411-413
    • Tewksbury, D.A.1    Tryon, E.S.2
  • 129
    • 0022457519 scopus 로고
    • High molecular weight angiotensinogen: A pregnancy associated protein
    • Tewksbury DA, Tryon ES, Burrill RE, Dart RA. High molecular weight angiotensinogen: a pregnancy associated protein. Clin Chim Acta 158: 7-12, 1986.
    • (1986) Clin Chim Acta , vol.158 , pp. 7-12
    • Tewksbury, D.A.1    Tryon, E.S.2    Burrill, R.E.3    Dart, R.A.4
  • 130
    • 84878301906 scopus 로고    scopus 로고
    • Chymase inhibition and cardiovascular protection
    • Tojo H, Urata H. Chymase inhibition and cardiovascular protection. Cardiovasc Drugs Ther 27: 139-143, 2013.
    • (2013) Cardiovasc Drugs Ther , vol.27 , pp. 139-143
    • Tojo, H.1    Urata, H.2
  • 131
    • 44949253157 scopus 로고    scopus 로고
    • Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart
    • Trask AJ, Jessup JA, Chappell MC, Ferrario CM. Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart. Am J Physiol Heart Circ Physiol 294: H2242-H2247, 2008.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294 , pp. H2242-H2247
    • Trask, A.J.1    Jessup, J.A.2    Chappell, M.C.3    Ferrario, C.M.4
  • 134
    • 84878643154 scopus 로고    scopus 로고
    • Non-ACE pathway-induced angiotensin II production
    • Uehara Y, Miura S, Yahiro E, Saku K. Non-ACE pathway-induced angiotensin II production. Curr Pharm Des 19: 3054-3059, 2013.
    • (2013) Curr Pharm Des , vol.19 , pp. 3054-3059
    • Uehara, Y.1    Miura, S.2    Yahiro, E.3    Saku, K.4
  • 136
    • 0347938213 scopus 로고    scopus 로고
    • Pathological involvement of chymase-dependent angiotensin II formation in the development of cardiovascular disease
    • Urata H. Pathological involvement of chymase-dependent angiotensin II formation in the development of cardiovascular disease. J Renin Angiotensin Aldosterone Syst 1: S35-S37, 2000.
    • (2000) J Renin Angiotensin Aldosterone Syst , vol.1 , pp. S35-S37
    • Urata, H.1
  • 137
    • 3943070448 scopus 로고    scopus 로고
    • [Involvement of chymase in pathogenesis of cardiovascular diseases]
    • Urata H. [Involvement of chymase in pathogenesis of cardiovascular diseases]. Nihon Rinsho 62, Suppl 3: 147-151, 2004.
    • (2004) Nihon Rinsho , vol.62 , pp. 147-151
    • Urata, H.1
  • 138
    • 18944402397 scopus 로고    scopus 로고
    • [Chymase-dependent angiotensin II-formation]
    • Urata H. [Chymase-dependent angiotensin II-formation]. Nihon Rinsho 63, Suppl 3: 60-64, 2005.
    • (2005) Nihon Rinsho , vol.63 , pp. 60-64
    • Urata, H.1
  • 139
    • 33847029092 scopus 로고    scopus 로고
    • Chymase and matrix metalloproteinase
    • Urata H. Chymase and matrix metalloproteinase. Hypertens Res 30: 3-4, 2007.
    • (2007) Hypertens Res , vol.30 , pp. 3-4
    • Urata, H.1
  • 141
    • 0027501757 scopus 로고
    • Cardiac angiotensin II formation: The angiotensin-I converting enzyme and human chymase
    • Urata H, Ganten D. Cardiac angiotensin II formation: the angiotensin-I converting enzyme and human chymase. Eur Heart J 14, Suppl I: 177-182, 1993.
    • (1993) Eur Heart J , vol.14 , pp. 177-182
    • Urata, H.1    Ganten, D.2
  • 142
    • 0025239660 scopus 로고
    • Angiotensin II-forming pathways in normal and failing human hearts
    • Urata H, Healy B, Stewart RW, Bumpus FM, Husain A. Angiotensin II-forming pathways in normal and failing human hearts. Circ Res 66: 883-890, 1990.
    • (1990) Circ Res , vol.66 , pp. 883-890
    • Urata, H.1    Healy, B.2    Stewart, R.W.3    Bumpus, F.M.4    Husain, A.5
  • 143
    • 0025598309 scopus 로고
    • Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart
    • Urata H, Kinoshita A, Misono KS, Bumpus FM, Husain A. Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart. J Biol Chem 265: 22348-22357, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 22348-22357
    • Urata, H.1    Kinoshita, A.2    Misono, K.S.3    Bumpus, F.M.4    Husain, A.5
  • 144
    • 0028028284 scopus 로고
    • Widespread tissue distribution of human chymase
    • Urata H, Strobel F, Ganten D. Widespread tissue distribution of human chymase. J Hypertens Suppl 12: S17-S22, 1994.
    • (1994) J Hypertens Suppl , vol.12 , pp. S17-S22
    • Urata, H.1    Strobel, F.2    Ganten, D.3
  • 146
    • 84863807562 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors reduce mortality in hypertension: A meta-analysis of randomized clinical trials of renin-angiotensin-aldosterone system inhibitors involving 158, 998 patients
    • van Vark LC, Bertrand M, Akkerhuis KM, Brugts JJ, Fox K, Mourad JJ, Boersma E. Angiotensin-converting enzyme inhibitors reduce mortality in hypertension: a meta-analysis of randomized clinical trials of renin-angiotensin-aldosterone system inhibitors involving 158, 998 patients. Eur Heart J 33: 2088-2097, 2012.
    • (2012) Eur Heart J , vol.33 , pp. 2088-2097
    • Van Vark, L.C.1    Bertrand, M.2    Akkerhuis, K.M.3    Brugts, J.J.4    Fox, K.5    Mourad, J.J.6    Boersma, E.7
  • 147
    • 84857099416 scopus 로고    scopus 로고
    • The epidemiological concept of residual risk
    • Vanuzzo D. The epidemiological concept of residual risk. Intern Emerg Med 6, Suppl 1: 45-51, 2011.
    • (2011) Intern Emerg Med , vol.6 , pp. 45-51
    • Vanuzzo, D.1
  • 148
    • 84876588807 scopus 로고    scopus 로고
    • Predominance of AT1 blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats
    • Varagic J, Ahmad S, VonCannon JL, Moniwa N, Brosnihan KB, Wysocki J, Batlle D, Ferrario CM. Predominance of AT1 blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats. Am J Hypertens 26: 583-590, 2013.
    • (2013) Am J Hypertens , vol.26 , pp. 583-590
    • Varagic, J.1    Ahmad, S.2    Voncannon, J.L.3    Moniwa, N.4    Brosnihan, K.B.5    Wysocki, J.6    Batlle, D.7    Ferrario, C.M.8
  • 152
    • 0035571572 scopus 로고    scopus 로고
    • Mast cell chymase inhibits smooth muscle cell growth and collagen expression in vitro: Transforming growth factor-beta1-dependent and -independent effects
    • Wang Y, Shiota N, Leskinen MJ, Lindstedt KA, Kovanen PT. Mast cell chymase inhibits smooth muscle cell growth and collagen expression in vitro: transforming growth factor-beta1-dependent and -independent effects. Arterioscler Thromb Vasc Biol 21: 1928-1933, 2001.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1928-1933
    • Wang, Y.1    Shiota, N.2    Leskinen, M.J.3    Lindstedt, K.A.4    Kovanen, P.T.5
  • 154
    • 84861183922 scopus 로고    scopus 로고
    • Divergent pathways for the angiotensin- (1-12) metabolism in the rat circulation and kidney
    • Westwood BM, Chappell MC. Divergent pathways for the angiotensin- (1-12) metabolism in the rat circulation and kidney. Peptides 35: 190-195, 2012.
    • (2012) Peptides , vol.35 , pp. 190-195
    • Westwood, B.M.1    Chappell, M.C.2
  • 157
    • 0025312050 scopus 로고
    • Purification and characterization of a kallikrein-like T-kininogenase
    • Xiong W, Chen LM, Chao J. Purification and characterization of a kallikrein-like T-kininogenase. J Biol Chem 265: 2822-2827, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 2822-2827
    • Xiong, W.1    Chen, L.M.2    Chao, J.3
  • 158
    • 39949084326 scopus 로고    scopus 로고
    • Chymase induces profibrotic response via transforming growth factor-beta 1/Smad activation in rat cardiac fibroblasts
    • Zhao XY, Zhao LY, Zheng QS, Su JL, Guan H, Shang FJ, Niu XL, He YP, Lu XL. Chymase induces profibrotic response via transforming growth factor-beta 1/Smad activation in rat cardiac fibroblasts. Mol Cell Biochem 310: 159-166, 2008.
    • (2008) Mol Cell Biochem , vol.310 , pp. 159-166
    • Zhao, X.Y.1    Zhao, L.Y.2    Zheng, Q.S.3    Su, J.L.4    Guan, H.5    Shang, F.J.6    Niu, X.L.7    He, Y.P.8    Lu, X.L.9
  • 159
    • 84930179081 scopus 로고    scopus 로고
    • GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number
    • Zhao Z, Wang H, Lin M, Groban L. GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number. Biochem Biophys Res Commun 459: 131-136, 2015.
    • (2015) Biochem Biophys Res Commun , vol.459 , pp. 131-136
    • Zhao, Z.1    Wang, H.2    Lin, M.3    Groban, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.