Angiotensin II formation from ACE and chymase in human and animal hearts: Methods and species considerations

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 273, Issue 4 42-4, 1997, Pages

  Balcells, Eduardo ^b   Meng, Qing C ^b   Johnson Jr , Walter H ^b   Oparil, Suzanne ^b   Dell'italia, Louis J ^a  

^a University of Alabama at Birmingham   (United States)

^b NONE

Author keywords

Angiotesinsin converting enzyme; Detergent renin angiotensin system

Indexed keywords

ANGIOTENSIN; CHYMASE; DIPEPTIDYL CARBOXYPEPTIDASE;

ANIMAL TISSUE; ARTICLE; DOG; ENZYME ACTIVITY; ENZYME LOCALIZATION; HORMONE SYNTHESIS; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPECIES DIFFERENCE; TISSUE DISTRIBUTION;

EID: 0030662137     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.273.4.h1769     Document Type: Article

References (19)

1. Balcells, E., Q. C. Meng, G. Hageman, R. W. Palmer, J. Durand, and L. J. Dell'Italia. Angiotensin II formation in dog heart is mediated by different pathways in vivo and in vitro. Am. J. Physiol. 271 (Heart Circ. Physiol. 40): H417-H471, 1996.
2. Chandrasekharan, U. M., S. Sanker, M. J. Glynias, S. S. Karnik, and A. Husain. Angiotensin II-forming activity in a reconstructed ancestral chymase. Science 271: 502-505, 1996.
3. Dell'Italia, L. J., Q. C. Meng, E. Balcells, I. M. Straeter-Knowlen, G. Hankes, R. Dillon, R. E. Cartee, R. Orr, S. P. Bishop, S. Oparil, and T. Elton. Increased ACE and chymase-like activity in cardiac tissue of dogs with chronic mitral regurgitation. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H2065-H2073, 1995.
4. Dzau, V. J. Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses. J. Hypertens. 7: 933-936, 1989.
5. 1 expression. Hypertension 23: 587-592, 1994.
6. Hoit, B. D., Y. Shao, A. Kinoshita, M. Gabel, A. Husain, and R. A. Walsh. Effects of angiotensin II generated by an angiotensin converting enzyme-independent pathway on left ventricular performance in the conscious baboon. J. Clin. Invest. 95: 1519-1527, 1995.
7. Husain, A. The chymase-angiotensin system in humans. J. Hypertens. 11: 1155-1159, 1993.
8. Husain, A., A. Kinoshita, S. S. Sung, H. Urata, and F. M. Bumpus. Human heart chymase. In: The Cardiac Renin-Angiotensin System, edited by K. Lindpaintner and D. Ganten. Armonk, NY: Futura, 1994, p. 309-332.
9. Iwai, N., H. Shimoike, and M. Kinoshita. Cardiac reninangiotensin system in the hypertrophied heart. Circulation 92: 2690-2696, 1995.
10. Johnston, C. I. Tissue angiotensin converting enzyme in cardiac and vascular hypertrophy, repair, and remodeling. Hypertension 23: 258-268, 1994.
11. Kinoshita, A., H. Urata, M. Bumpus, and A. Husain. Measurement of angiotensin I converting enzyme inhibition in the heart. Circ. Res. 73: 51-60, 1993.
12. Lindpainter, K., M. Jin, M. J. Wilhelm, F. Suzuki, W. Linz, B. A. Schoelkens, and D. Ganten. Intracardiac generation of angiotensin and its physiologic role. Circulation 77, Suppl.: 1-18, 1988.
13. Le Trong, H., H. Neurath, and R. G. Woodbury. Substrate specificity of the chymotrypsin-like protease in secretory granules isolated from rat mast cells. Proc. Natl. Acad. Sci. USA 84: 364-367, 1987.
14. Lowry, O. H., N. J. Rosebrough, A. T. Farr, and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
15. 1 receptor antagonist, and surgical reversal. J. Cardiovasc. Pharmacol. 23: 291-299, 1994.
16. Okunishi, H., Y. Oka, N. Shiota, T. Kawamoto, K. Song, and M. Miyazaki. Marked species difference in the vascular angiotensin II-forming pathways: humans vs. rodents. Jpn. J. Pharmacol. 62: 207-210, 1993.
17. Pieruzzi, F., Z. A. Abassi, and H. R. Keiser. Expression of renin-angiotensin system components in the heart, kidneys, and lungs of rats with experimental heart failure. Circulation 92: 3105-3112, 1995.
18. Regan, C. P., P. G. Anderson, S. P. Bishop, and K. H. Berecek. Captopril prevents vascular and fibrotic changes but not cardiac hypertrophy in aortic-banded rats. Am. J. Physiol. 271 (Heart Circ. Physiol. 40): H906-H913, 1996.
19. Ruzicka, M. B., E. Yuan, E. Harmsen, and F. H. H. Leenen. The renin-angiotensin system and volume overload-induced cardiac hypertrophy in rats. Effects of angiotensin converting enzyme inhibitor versus angiotensin II receptor blocker. Circulation 87: 921-930, 1993.