-
1
-
-
83255175529
-
Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue
-
Ahmad S, Simmons T, Varagic J, Moniwa N, Chappell MC, Ferrario CM. Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue. PLoS One 6: e28501, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Ahmad, S.1
Simmons, T.2
Varagic, J.3
Moniwa, N.4
Chappell, M.C.5
Ferrario, C.M.6
-
2
-
-
79251592234
-
Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes
-
Ahmad S, Varagic J, Westwood BM, Chappell MC, Ferrario CM. Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes. PLoS One 6: e15759, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Ahmad, S.1
Varagic, J.2
Westwood, B.M.3
Chappell, M.C.4
Ferrario, C.M.5
-
3
-
-
84875370725
-
Chymase mediates angiotensin-(1-12) metabolism in normal human hearts
-
Ahmad S, Wei CC, Tallaj J, Dell=Italia LJ, Moniwa N, Varagic J, Ferrario CM. Chymase mediates angiotensin-(1-12) metabolism in normal human hearts. J Am Soc Hypertens 7: 128-136, 2013.
-
(2013)
J Am Soc Hypertens
, vol.7
, pp. 128-136
-
-
Ahmad, S.1
Wei, C.C.2
Tallaj, J.3
DellItalia, L.J.4
Moniwa, N.5
Varagic, J.6
Ferrario, C.M.7
-
4
-
-
0034573129
-
Activity of chymotrypsin-like proteinases in patients with ischemic heart disease, arterial hypertension and nonspecific aortic arteritis
-
Arabidze GG, Belova LA, Chikhladze NM, Shapkina LS, Ogorodnikova OG, Kukharchuk VV. [Activity of chymotrypsin-like proteinases in patients with ischemic heart disease, arterial hypertension and nonspecific aortic arteritis]. Ter Arkh 72: 36-39, 2000.
-
(2000)
Ter Arkh
, vol.72
, pp. 36-39
-
-
Arabidze, G.G.1
Belova, L.A.2
Chikhladze, N.M.3
Shapkina, L.S.4
Ogorodnikova, O.G.5
Kukharchuk, V.V.6
-
5
-
-
77956671617
-
Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus
-
Arnold AC, Isa K, Shaltout HA, Nautiyal M, Ferrario CM, Chappell MC, Diz DI. Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus. Am J Physiol Heart Circ Physiol 299: H763-H771, 2010.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.299
-
-
Arnold, A.C.1
Isa, K.2
Shaltout, H.A.3
Nautiyal, M.4
Ferrario, C.M.5
Chappell, M.C.6
Diz, D.I.7
-
6
-
-
33750707643
-
Angiotensin II formation in dog heart is mediated by different pathways in vivo and in vitro
-
Balcells E, Meng QC, Hageman GR, Palmer RW, Durand JN, Dell=Italia LJ. Angiotensin II formation in dog heart is mediated by different pathways in vivo and in vitro. Am J Physiol Heart Circ Physiol 271: H417-H421, 1996.
-
(1996)
Am J Physiol Heart Circ Physiol
, vol.271
-
-
Balcells, E.1
Meng, Q.C.2
Hageman, G.R.3
Palmer, R.W.4
Durand, J.N.5
DellItalia, L.J.6
-
7
-
-
0030662137
-
Angiotensin II formation from ACE and chymase in human and animal hearts: Methods and species considerations
-
Balcells E, Meng QC, Johnson WH Jr, Oparil S, Dell=Italia LJ. Angiotensin II formation from ACE and chymase in human and animal hearts: methods and species considerations. Am J Physiol Heart Circ Physiol 273: H1769-H1774, 1997.
-
(1997)
Am J Physiol Heart Circ Physiol
, vol.273
-
-
Balcells, E.1
Meng, Q.C.2
Johnson Jr., W.H.3
Oparil, S.4
DellItalia, L.J.5
-
8
-
-
34548851716
-
Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: More than regulation of blood pressure?
-
Chappell MC. Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: more than regulation of blood pressure? Hypertension 50: 596-599, 2007.
-
(2007)
Hypertension
, vol.50
, pp. 596-599
-
-
Chappell, M.C.1
-
9
-
-
0034996749
-
Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat
-
Chatterjee PK, Brown PA, Cuzzocrea S, Zacharowski K, Stewart KN, Mota-Filipe H, McDonald MC, Thiemermann C. Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat. Kidney Int 59: 2073-2083, 2001.
-
(2001)
Kidney Int
, vol.59
, pp. 2073-2083
-
-
Chatterjee, P.K.1
Brown, P.A.2
Cuzzocrea, S.3
Zacharowski, K.4
Stewart, K.N.5
Mota-Filipe, H.6
McDonald, M.C.7
Thiemermann, C.8
-
10
-
-
78651318031
-
Cardiovascular responses elicited by a new endogenous angiotensin in the nucleus tractus solitarius of the rat
-
Chitravanshi VC, Sapru HN. Cardiovascular responses elicited by a new endogenous angiotensin in the nucleus tractus solitarius of the rat. Am J Physiol Heart Circ Physiol 300: H230-H240, 2011.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
-
-
Chitravanshi, V.C.1
Sapru, H.N.2
-
11
-
-
0036023644
-
Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases
-
Dell=Italia LJ, Husain A. Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases. Curr Opin Cardiol 17: 374-379, 2002.
-
(2002)
Curr Opin Cardiol
, vol.17
, pp. 374-379
-
-
DellItalia, L.J.1
Husain, A.2
-
12
-
-
0029587599
-
Increased ACE and chymase-like activity in cardiac tissue of dogs with chronic mitral regurgitation
-
Dell=Italia LJ, Meng QC, Balcells E, Straeter-Knowlen IM, Hankes GH, Dillon R, Cartee RE, Orr R, Bishop SP, Oparil S. Increased ACE and chymase-like activity in cardiac tissue of dogs with chronic mitral regurgitation. Am J Physiol Heart Circ Physiol 269: H2065-H2073, 1995.
-
(1995)
Am J Physiol Heart Circ Physiol
, vol.269
-
-
DellItalia, L.J.1
Meng, Q.C.2
Balcells, E.3
Straeter-Knowlen, I.M.4
Hankes, G.H.5
Dillon, R.6
Cartee, R.E.7
Orr, R.8
Bishop, S.P.9
Oparil, S.10
-
13
-
-
76849103296
-
Addressing the theoretical and clinical advantages of combination therapy with inhibitors of the renin-angiotensin-aldosterone system: Antihypertensive effects and benefits beyond BP control
-
Ferrario CM. Addressing the theoretical and clinical advantages of combination therapy with inhibitors of the renin-angiotensin-aldosterone system: antihypertensive effects and benefits beyond BP control. Life Sci 86: 289-299, 2010.
-
(2010)
Life Sci
, vol.86
, pp. 289-299
-
-
Ferrario, C.M.1
-
14
-
-
74949092226
-
New physiological concepts of the renin-angiotensin system from the investigation of precursors and products of angiotensin I metabolism
-
Ferrario CM. New physiological concepts of the renin-angiotensin system from the investigation of precursors and products of angiotensin I metabolism. Hypertension 55: 445-452, 2010.
-
(2010)
Hypertension
, vol.55
, pp. 445-452
-
-
Ferrario, C.M.1
-
15
-
-
30944453306
-
Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors
-
Ferrario CM, Jessup J, Gallagher PE, Averill DB, Brosnihan KB, Ann TE, Smith RD, Chappell MC. Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors. Kidney Int 68: 2189-2196, 2005.
-
(2005)
Kidney Int
, vol.68
, pp. 2189-2196
-
-
Ferrario, C.M.1
Jessup, J.2
Gallagher, P.E.3
Averill, D.B.4
Brosnihan, K.B.5
Ann, T.E.6
Smith, R.D.7
Chappell, M.C.8
-
16
-
-
66249098883
-
Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy
-
Ferrario CM, Varagic J, Habibi J, Nagata S, Kato J, Chappell MC, Trask AJ, Kitamura K, Whaley-Connell A, Sowers JR. Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy. Am J Physiol Heart Circ Physiol 296: H1184-H1192, 2009.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
-
-
Ferrario, C.M.1
Varagic, J.2
Habibi, J.3
Nagata, S.4
Kato, J.5
Chappell, M.C.6
Trask, A.J.7
Kitamura, K.8
Whaley-Connell, A.9
Sowers, J.R.10
-
17
-
-
0027442410
-
The chymase-angiotensin system in humans
-
Husain A. The chymase-angiotensin system in humans. J Hypertens 11: 1155-1159, 1993.
-
(1993)
J Hypertens
, vol.11
, pp. 1155-1159
-
-
Husain, A.1
-
18
-
-
67650081011
-
Chronic immunoneutralization of brain angiotensin-(1-12) lowers blood pressure in transgenic (mRen2)27 hypertensive rats
-
Isa K, Garcia-Espinosa MA, Arnold AC, Pirro NT, Tommasi EN, Ganten D, Chappell MC, Ferrario CM, Diz DI. Chronic immunoneutralization of brain angiotensin-(1-12) lowers blood pressure in transgenic (mRen2)27 hypertensive rats. Am J Physiol Regul Integr Comp Physiol 297: R111-R115, 2009.
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.297
-
-
Isa, K.1
Garcia-Espinosa, M.A.2
Arnold, A.C.3
Pirro, N.T.4
Tommasi, E.N.5
Ganten, D.6
Chappell, M.C.7
Ferrario, C.M.8
Diz, D.I.9
-
19
-
-
33751188726
-
Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats
-
Jessup JA, Gallagher PE, Averill DB, Brosnihan KB, Tallant EA, Chappell MC, Ferrario CM. Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats. Am J Physiol Heart Circ Physiol 291: H2166-H2172, 2006.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
-
-
Jessup, J.A.1
Gallagher, P.E.2
Averill, D.B.3
Brosnihan, K.B.4
Tallant, E.A.5
Chappell, M.C.6
Ferrario, C.M.7
-
20
-
-
3242769190
-
Involvement of chymase-mediated angiotensin II generation in blood pressure regulation
-
Li M, Liu K, Michalicek J, Angus JA, Hunt JE, Dell=Italia LJ, Feneley MP, Graham RM, Husain A. Involvement of chymase-mediated angiotensin II generation in blood pressure regulation. J Clin Invest 114: 112-120, 2004.
-
(2004)
J Clin Invest
, vol.114
, pp. 112-120
-
-
Li, M.1
Liu, K.2
Michalicek, J.3
Angus, J.A.4
Hunt, J.E.5
DellItalia, L.J.6
Feneley, M.P.7
Graham, R.M.8
Husain, A.9
-
21
-
-
33750032795
-
Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models
-
Miyazaki M, Takai S, Jin D, Muramatsu M. Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models. Pharmacol Ther 112: 668-676, 2006.
-
(2006)
Pharmacol Ther
, vol.112
, pp. 668-676
-
-
Miyazaki, M.1
Takai, S.2
Jin, D.3
Muramatsu, M.4
-
22
-
-
84856762891
-
Restoration of the blood pressure circadian rhythm by direct renin inhibition and blockade of angiotensin II receptors in mRen2. Lewis hypertensive rats
-
Moniwa N, Varagic J, Ahmad S, Voncannon JL, Ferrario CM. Restoration of the blood pressure circadian rhythm by direct renin inhibition and blockade of angiotensin II receptors in mRen2. Lewis hypertensive rats. Ther Adv Cardiovasc Dis 6: 15-29, 2012.
-
(2012)
Ther Adv Cardiovasc Dis
, vol.6
, pp. 15-29
-
-
Moniwa, N.1
Varagic, J.2
Ahmad, S.3
Voncannon, J.L.4
Ferrario, C.M.5
-
23
-
-
84873055854
-
Hemodynamic and hormonal changes to dual renin-angiotensin system inhibition in experimental hypertension
-
Moniwa N, Varagic J, Ahmad S, Voncannon JL, Simington SW, Wang H, Groban L, Brosnihan KB, Nagata S, Kato J, Kitamura K, Gomez RA, Lopez ML, Ferrario CM. Hemodynamic and hormonal changes to dual renin-angiotensin system inhibition in experimental hypertension. Hypertension 61: 417-424, 2013.
-
(2013)
Hypertension
, vol.61
, pp. 417-424
-
-
Moniwa, N.1
Varagic, J.2
Ahmad, S.3
Voncannon, J.L.4
Simington, S.W.5
Wang, H.6
Groban, L.7
Brosnihan, K.B.8
Nagata, S.9
Kato, J.10
Kitamura, K.11
Gomez, R.A.12
Lopez, M.L.13
Ferrario, C.M.14
-
24
-
-
84856746787
-
Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system
-
Nagata S, Kato J, Kuwasako K, Asami M, Kitamura K. Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system. Hypertens Res 35: 234-238, 2012.
-
(2012)
Hypertens Res
, vol.35
, pp. 234-238
-
-
Nagata, S.1
Kato, J.2
Kuwasako, K.3
Asami, M.4
Kitamura, K.5
-
25
-
-
77951257899
-
Plasma and tissue levels of proangiotensin-12 and components of the renin-angiotensin system (RAS) following low-or high-salt feeding in rats
-
Nagata S, Kato J, Kuwasako K, Kitamura K. Plasma and tissue levels of proangiotensin-12 and components of the renin-angiotensin system (RAS) following low-or high-salt feeding in rats. Peptides 31: 889-892, 2010.
-
(2010)
Peptides
, vol.31
, pp. 889-892
-
-
Nagata, S.1
Kato, J.2
Kuwasako, K.3
Kitamura, K.4
-
26
-
-
33750147612
-
Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system
-
Nagata S, Kato J, Sasaki K, Minamino N, Eto T, Kitamura K. Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system. Biochem Biophys Res Commun 350: 1026-1031, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.350
, pp. 1026-1031
-
-
Nagata, S.1
Kato, J.2
Sasaki, K.3
Minamino, N.4
Eto, T.5
Kitamura, K.6
-
27
-
-
77958511663
-
Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation
-
Pat B, Chen Y, Killingsworth C, Gladden JD, Shi K, Zheng J, Powell PC, Walcott G, Ahmed MI, Gupta H, Desai R, Wei CC, Hase N, Kobayashi T, Sabri A, Granzier H, Denney T, Tillson M, Dillon AR, Husain A, Dell=Italia LJ. Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation. Circulation 122: 1488-1495, 2010.
-
(2010)
Circulation
, vol.122
, pp. 1488-1495
-
-
Pat, B.1
Chen, Y.2
Killingsworth, C.3
Gladden, J.D.4
Shi, K.5
Zheng, J.6
Powell, P.C.7
Walcott, G.8
Ahmed, M.I.9
Gupta, H.10
Desai, R.11
Wei, C.C.12
Hase, N.13
Kobayashi, T.14
Sabri, A.15
Granzier, H.16
Denney, T.17
Tillson, M.18
Dillon, A.R.19
Husain, A.20
DellItalia, L.J.21
more..
-
28
-
-
62349100153
-
Cardiac chymase converts rat proAngiotensin-12 (PA12) to angiotensin II: Effects of PA12 upon cardiac haemodynamics
-
Prosser HC, Forster ME, Richards AM, Pemberton CJ. Cardiac chymase converts rat proAngiotensin-12 (PA12) to angiotensin II: effects of PA12 upon cardiac haemodynamics. Cardiovasc Res 82: 40-50, 2009.
-
(2009)
Cardiovasc Res
, vol.82
, pp. 40-50
-
-
Prosser, H.C.1
Forster, M.E.2
Richards, A.M.3
Pemberton, C.J.4
-
29
-
-
78249238801
-
Regional vascular response to ProAngiotensin-12 (PA12) through the rat arterial system
-
Prosser HC, Richards AM, Forster ME, Pemberton CJ. Regional vascular response to ProAngiotensin-12 (PA12) through the rat arterial system. Peptides 31: 1540-1545, 2010.
-
(2010)
Peptides
, vol.31
, pp. 1540-1545
-
-
Prosser, H.C.1
Richards, A.M.2
Forster, M.E.3
Pemberton, C.J.4
-
30
-
-
84859510328
-
Multiple mechanisms for the action of chymase inhibitors
-
Takai S, Jin D, Miyazaki M. Multiple mechanisms for the action of chymase inhibitors. J Pharmacol Sci 118: 311-316, 2012.
-
(2012)
J Pharmacol Sci
, vol.118
, pp. 311-316
-
-
Takai, S.1
Jin, D.2
Miyazaki, M.3
-
32
-
-
43449113848
-
New angiotensins
-
Varagic J, Trask AJ, Jessup JA, Chappell MC, Ferrario CM. New angiotensins. J Mol Med 86: 663-671, 2008.
-
(2008)
J Mol Med
, vol.86
, pp. 663-671
-
-
Varagic, J.1
Trask, A.J.2
Jessup, J.A.3
Chappell, M.C.4
Ferrario, C.M.5
-
33
-
-
0036840510
-
The renin-angiotensin system as a risk factor and therapeutic target for cardiovascular and renal disease
-
Volpe M, Savoia C, De PP, Ostrowska B, Tarasi D, Rubattu S. The renin-angiotensin system as a risk factor and therapeutic target for cardiovascular and renal disease. J Am Soc Nephrol 13, Suppl 3: S173-S178, 2002.
-
(2002)
J Am Soc Nephrol
, vol.13
, Issue.SUPPL. 3
-
-
Volpe, M.1
Savoia, C.2
De, P.P.3
Ostrowska, B.4
Tarasi, D.5
Rubattu, S.6
-
34
-
-
77955103495
-
Elevated plasma chymotrypsin-like protease (chymase) activity in women with preeclampsia
-
Wang Y, Gu Y, Lewis DF, Alexander JS, Granger DN. Elevated plasma chymotrypsin-like protease (chymase) activity in women with preeclampsia. Hypertens Pregnancy 29: 253-261, 2010.
-
(2010)
Hypertens Pregnancy
, vol.29
, pp. 253-261
-
-
Wang, Y.1
Gu, Y.2
Lewis, D.F.3
Alexander, J.S.4
Granger, D.N.5
-
35
-
-
84863104638
-
Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss
-
Wei CC, Chen Y, Powell LC, Zheng J, Shi K, Bradley WE, Powell PC, Ahmad S, Ferrario CM, Dell=Italia LJ. Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss. PLoS One 7: e40110, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Wei, C.C.1
Chen, Y.2
Powell, L.C.3
Zheng, J.4
Shi, K.5
Bradley, W.E.6
Powell, P.C.7
Ahmad, S.8
Ferrario, C.M.9
DellItalia, L.J.10
-
36
-
-
77951171609
-
Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents
-
Wei CC, Hase N, Inoue Y, Bradley EW, Yahiro E, Li M, Naqvi N, Powell PC, Shi K, Takahashi Y, Saku K, Urata H, Dell=Italia LJ, Husain A. Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents. J Clin Invest 120: 1229-1239, 2010.
-
(2010)
J Clin Invest
, vol.120
, pp. 1229-1239
-
-
Wei, C.C.1
Hase, N.2
Inoue, Y.3
Bradley, E.W.4
Yahiro, E.5
Li, M.6
Naqvi, N.7
Powell, P.C.8
Shi, K.9
Takahashi, Y.10
Saku, K.11
Urata, H.12
DellItalia, L.J.13
Husain, A.14
-
37
-
-
0033398149
-
The renin-angiotensin-aldosterone system: A specific target for hypertension management
-
Weir MR, Dzau VJ. The renin-angiotensin-aldosterone system: a specific target for hypertension management. Am J Hypertens 12: 205S-213S, 1999.
-
(1999)
Am J Hypertens
, vol.12
-
-
Weir, M.R.1
Dzau, V.J.2
-
38
-
-
84861183922
-
Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney
-
Westwood BM, Chappell MC. Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney. Peptides 35: 190-195, 2012.
-
(2012)
Peptides
, vol.35
, pp. 190-195
-
-
Westwood, B.M.1
Chappell, M.C.2
|