Mast cell chymase induces smooth muscle cell apoptosis by a mechanism involving fibronectin degradation and disruption of focal adhesions

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 23, Issue 2, 2003, Pages 238-243

  Leskinen, Markus J ^a   Lindstedt, Ken A ^a   Wang, Yenfeng ^a   Kovanen, Petri T ^a  

^a WIHURI RESEARCH INSTITUTE   (Finland)

Author keywords

Apoptosis; Chymase; Focal adhesion kinase; Mast cell; Smooth muscle cell

Indexed keywords

CATHEPSIN G; CHYMASE; CHYMOTRYPSIN A; COMPOUND 48-80; ELASTASE; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; SCLEROPROTEIN; TRYPSIN; VANADATE SODIUM;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL INTERACTION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; EXTRACELLULAR MATRIX; FLUORESCENCE ACTIVATED CELL SORTING; FOCAL ADHESION; IMMUNOHISTOCHEMISTRY; MALE; MAST CELL; MEMBRANE DAMAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

ANIMALS; AORTA; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CHYMASES; FIBRONECTINS; FOCAL ADHESIONS; MALE; MAST CELLS; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, WISTAR; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION;

EID: 0037324287     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000051405.68811.4D     Document Type: Article

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