Installing hydrolytic activity into a completely de novo protein framework

Nature Chemistry

Volumn 8, Issue 9, 2016, Pages 837-844

  Burton, Antony J ^a   Thomson, Andrew R ^a   Dawson, William M ^a   Brady, R Leo ^a   Woolfson, Derek N ^a,b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b Tankard's Close   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4-NITROPHENYL ACETATE; CARBOXYLESTERASE; NITROPHENOL;

ALPHA HELIX; CATALYSIS; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; HYDROLYSIS; KINETICS; MUTATION; PROCEDURES; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE;

CARBOXYLIC ESTER HYDROLASES; CATALYSIS; CATALYTIC DOMAIN; HYDROLYSIS; KINETICS; MUTATION; NITROPHENOLS; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY;

EID: 84983605294     PISSN: 17554330     EISSN: 17554349     Source Type: Journal    
DOI: 10.1038/nchem.2555     Document Type: Article

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