A designed supramolecular protein assembly with in vivo enzymatic activity

Science

Volumn 346, Issue 6216, 2014, Pages 1525-1528

  Song, Woon Ju ^a   Tezcan, F Akif ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; METALLO BETA LACTAMASE; TETRAMER; ZINC ION; BETA LACTAMASE; METALLOPROTEIN; ZINC;

CATALYSIS; ENZYME ACTIVITY; FECAL COLIFORM; HYDROLYSIS; PROTEIN; SUBSTRATE;

ARTICLE; BACTERIAL SURVIVAL; BINDING AFFINITY; CRYSTAL STRUCTURE; CYTOPLASM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; FLAME PHOTOMETRY; HYDROLYSIS; IN VIVO STUDY; MOLECULAR DOCKING; NONHUMAN; OLIGOMERIZATION; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN STRUCTURE; SUPRAMOLECULAR CHEMISTRY; ULTRACENTRIFUGATION; CATALYSIS; CHEMISTRY; DIRECTED MOLECULAR EVOLUTION; DRUG EFFECTS; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; MUTATION; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI;

AMPICILLIN; BETA-LACTAMASES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIRECTED MOLECULAR EVOLUTION; ESCHERICHIA COLI; HYDROLYSIS; METALLOPROTEINS; MUTATION; PERIPLASM; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY; ZINC;

EID: 84919425588     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1259680     Document Type: Article

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