-
1
-
-
84880839435
-
Gene-pair expression signatures reveal lineage control
-
Heinaniemi M, Nykter M, Kramer R, Wienecke-Baldacchino A, Sinkkonen L, Zhou JX, Kreisberg R, Kauffman SA, Huang S, Shmulevich I. Gene-pair expression signatures reveal lineage control. Nat Methods. 2013;10:577-83.
-
(2013)
Nat Methods.
, vol.10
, pp. 577-583
-
-
Heinaniemi, M.1
Nykter, M.2
Kramer, R.3
Wienecke-Baldacchino, A.4
Sinkkonen, L.5
Zhou, J.X.6
Kreisberg, R.7
Kauffman, S.A.8
Huang, S.9
Shmulevich, I.10
-
2
-
-
77953466536
-
Nuclear reprogramming to a pluripotent state by three approaches
-
Yamanaka S, Blau HM. Nuclear reprogramming to a pluripotent state by three approaches. Nature. 2010;465:704-12.
-
(2010)
Nature.
, vol.465
, pp. 704-712
-
-
Yamanaka, S.1
Blau, H.M.2
-
4
-
-
33846576622
-
Epigenetic stem cell signature in cancer
-
Widschwendter M, Fiegl H, Egle D, Mueller-Holzner E, Spizzo G, Marth C, Weisenberger DJ, Campan M, Young J, Jacobs I, Laird PW. Epigenetic stem cell signature in cancer. Nat Genet. 2007;39:157-8.
-
(2007)
Nat Genet.
, vol.39
, pp. 157-158
-
-
Widschwendter, M.1
Fiegl, H.2
Egle, D.3
Mueller-Holzner, E.4
Spizzo, G.5
Marth, C.6
Weisenberger, D.J.7
Campan, M.8
Young, J.9
Jacobs, I.10
Laird, P.W.11
-
5
-
-
33846569960
-
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
-
Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet. 2007;39:237-42.
-
(2007)
Nat Genet.
, vol.39
, pp. 237-242
-
-
Ohm, J.E.1
McGarvey, K.M.2
Yu, X.3
Cheng, L.4
Schuebel, K.E.5
Cope, L.6
Mohammad, H.P.7
Chen, W.8
Daniel, V.C.9
Yu, W.10
-
6
-
-
33644846509
-
Epigenetic gene silencing in cancer--a mechanism for early oncogenic pathway addiction?
-
Baylin SB, Ohm JE. Epigenetic gene silencing in cancer--a mechanism for early oncogenic pathway addiction? Nat Rev Cancer. 2006;6:107-16.
-
(2006)
Nat Rev Cancer.
, vol.6
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
7
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet. 2002;3:415-28.
-
(2002)
Nat Rev Genet.
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
8
-
-
84907033777
-
Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer
-
Saha SK, Parachoniak CA, Ghanta KS, Fitamant J, Ross KN, Najem MS, Gurumurthy S, Akbay EA, Sia D, Cornella H, et al. Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer. Nature. 2014;513:110-4.
-
(2014)
Nature.
, vol.513
, pp. 110-114
-
-
Saha, S.K.1
Parachoniak, C.A.2
Ghanta, K.S.3
Fitamant, J.4
Ross, K.N.5
Najem, M.S.6
Gurumurthy, S.7
Akbay, E.A.8
Sia, D.9
Cornella, H.10
-
9
-
-
84858796262
-
IDH mutation impairs histone demethylation and results in a block to cell differentiation
-
Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature. 2012;483:474-8.
-
(2012)
Nature.
, vol.483
, pp. 474-478
-
-
Lu, C.1
Ward, P.S.2
Kapoor, G.S.3
Rohle, D.4
Turcan, S.5
Abdel-Wahab, O.6
Edwards, C.R.7
Khanin, R.8
Figueroa, M.E.9
Melnick, A.10
-
10
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 2006;125:315-26.
-
(2006)
Cell.
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
-
11
-
-
33646865180
-
Control of developmental regulators by Polycomb in human embryonic stem cells
-
Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell. 2006;125:301-13.
-
(2006)
Cell.
, vol.125
, pp. 301-313
-
-
Lee, T.I.1
Jenner, R.G.2
Boyer, L.A.3
Guenther, M.G.4
Levine, S.S.5
Kumar, R.M.6
Chevalier, B.7
Johnstone, S.E.8
Cole, M.F.9
Isono, K.10
-
12
-
-
33846649587
-
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
-
Schlesinger Y, Straussman R, Keshet I, Farkash S, Hecht M, Zimmerman J, Eden E, Yakhini Z, Ben-Shushan E, Reubinoff BE, et al. Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet. 2007;39:232-6.
-
(2007)
Nat Genet.
, vol.39
, pp. 232-236
-
-
Schlesinger, Y.1
Straussman, R.2
Keshet, I.3
Farkash, S.4
Hecht, M.5
Zimmerman, J.6
Eden, E.7
Yakhini, Z.8
Ben-Shushan, E.9
Reubinoff, B.E.10
-
13
-
-
77950650405
-
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer
-
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H, Bell CG, Maxwell AP, et al. Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res. 2010;20:440-6.
-
(2010)
Genome Res.
, vol.20
, pp. 440-446
-
-
Teschendorff, A.E.1
Menon, U.2
Gentry-Maharaj, A.3
Ramus, S.J.4
Weisenberger, D.J.5
Shen, H.6
Campan, M.7
Noushmehr, H.8
Bell, C.G.9
Maxwell, A.P.10
-
14
-
-
77950657253
-
Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains
-
Rakyan VK, Down TA, Maslau S, Andrew T, Yang TP, Beyan H, Whittaker P, McCann OT, Finer S, Valdes AM, et al. Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains. Genome Res. 2010;20:434-9.
-
(2010)
Genome Res.
, vol.20
, pp. 434-439
-
-
Rakyan, V.K.1
Down, T.A.2
Maslau, S.3
Andrew, T.4
Yang, T.P.5
Beyan, H.6
Whittaker, P.7
McCann, O.T.8
Finer, S.9
Valdes, A.M.10
-
15
-
-
84872806231
-
Genome-wide methylation profiles reveal quantitative views of human aging rates
-
Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, Klotzle B, Bibikova M, Fan JB, Gao Y, et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol Cell. 2013;49:359-67.
-
(2013)
Mol Cell.
, vol.49
, pp. 359-367
-
-
Hannum, G.1
Guinney, J.2
Zhao, L.3
Zhang, L.4
Hughes, G.5
Sadda, S.6
Klotzle, B.7
Bibikova, M.8
Fan, J.B.9
Gao, Y.10
-
16
-
-
84933278041
-
Whole-genome fingerprint of the DNA methylome during human B cell differentiation
-
Kulis M, Merkel A, Heath S, Queiros AC, Schuyler RP, Castellano G, Beekman R, Raineri E, Esteve A, Clot G, et al. Whole-genome fingerprint of the DNA methylome during human B cell differentiation. Nat Genet. 2015;47:746-56.
-
(2015)
Nat Genet.
, vol.47
, pp. 746-756
-
-
Kulis, M.1
Merkel, A.2
Heath, S.3
Queiros, A.C.4
Schuyler, R.P.5
Castellano, G.6
Beekman, R.7
Raineri, E.8
Esteve, A.9
Clot, G.10
-
17
-
-
84866844032
-
Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns
-
Sproul D, Kitchen RR, Nestor CE, Dixon JM, Sims AH, Harrison DJ, Ramsahoye BH, Meehan RR. Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns. Genome Biol. 2012;13:R84.
-
(2012)
Genome Biol.
, vol.13
, pp. R84
-
-
Sproul, D.1
Kitchen, R.R.2
Nestor, C.E.3
Dixon, J.M.4
Sims, A.H.5
Harrison, D.J.6
Ramsahoye, B.H.7
Meehan, R.R.8
-
18
-
-
84896501999
-
Molecular rules governing de novo methylation in cancer
-
Nejman D, Straussman R, Steinfeld I, Ruvolo M, Roberts D, Yakhini Z, Cedar H. Molecular rules governing de novo methylation in cancer. Cancer Res. 2014;74:1475-83.
-
(2014)
Cancer Res.
, vol.74
, pp. 1475-1483
-
-
Nejman, D.1
Straussman, R.2
Steinfeld, I.3
Ruvolo, M.4
Roberts, D.5
Yakhini, Z.6
Cedar, H.7
-
19
-
-
84860643156
-
Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives
-
Nazor KL, Altun G, Lynch C, Tran H, Harness JV, Slavin I, Garitaonandia I, Muller FJ, Wang YC, Boscolo FS, et al. Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives. Cell Stem Cell. 2012;10:620-34.
-
(2012)
Cell Stem Cell.
, vol.10
, pp. 620-634
-
-
Nazor, K.L.1
Altun, G.2
Lynch, C.3
Tran, H.4
Harness, J.V.5
Slavin, I.6
Garitaonandia, I.7
Muller, F.J.8
Wang, Y.C.9
Boscolo, F.S.10
-
20
-
-
52149097555
-
Regulatory networks define phenotypic classes of human stem cell lines
-
Muller FJ, Laurent LC, Kostka D, Ulitsky I, Williams R, Lu C, Park IH, Rao MS, Shamir R, Schwartz PH, et al. Regulatory networks define phenotypic classes of human stem cell lines. Nature. 2008;455:401-5.
-
(2008)
Nature.
, vol.455
, pp. 401-405
-
-
Muller, F.J.1
Laurent, L.C.2
Kostka, D.3
Ulitsky, I.4
Williams, R.5
Lu, C.6
Park, I.H.7
Rao, M.S.8
Shamir, R.9
Schwartz, P.H.10
-
21
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3:Article3.
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
-
-
Smyth, G.K.1
-
22
-
-
12344330424
-
limmaGUI: a graphical user interface for linear modeling of microarray data
-
Wettenhall JM, Smyth GK. limmaGUI: a graphical user interface for linear modeling of microarray data. Bioinformatics. 2004;20:3705-6.
-
(2004)
Bioinformatics
, vol.20
, pp. 3705-3706
-
-
Wettenhall, J.M.1
Smyth, G.K.2
-
23
-
-
84905029258
-
Comprehensive molecular profiling of lung adenocarcinoma
-
Cancer Genome Atlas Research N. Comprehensive molecular profiling of lung adenocarcinoma. Nature. 2014;511:543-50.
-
(2014)
Nature
, vol.511
, pp. 543-550
-
-
-
24
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
Cancer Genome Atlas Research N. Comprehensive genomic characterization of squamous cell lung cancers. Nature. 2012;489:519-25.
-
(2012)
Nature
, vol.489
, pp. 519-525
-
-
-
25
-
-
84879890360
-
Comprehensive molecular characterization of clear cell renal cell carcinoma
-
Cancer Genome Atlas Research N. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature. 2013;499:43-9.
-
(2013)
Nature
, vol.499
, pp. 43-49
-
-
-
26
-
-
84954286974
-
Comprehensive molecular characterization of papillary renal-cell carcinoma
-
Cancer Genome Atlas Research N, Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, et al. Comprehensive molecular characterization of papillary renal-cell carcinoma. N Engl J Med. 2016;374:135-45.
-
(2016)
N Engl J Med
, vol.374
, pp. 135-145
-
-
Linehan, W.M.1
Spellman, P.T.2
Ricketts, C.J.3
Creighton, C.J.4
Fei, S.S.5
Davis, C.6
Wheeler, D.A.7
Murray, B.A.8
Schmidt, L.9
-
27
-
-
84897022815
-
Comprehensive molecular characterization of urothelial bladder carcinoma
-
Cancer Genome Atlas Research N. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature. 2014;507:315-22.
-
(2014)
Nature
, vol.507
, pp. 315-322
-
-
-
28
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
Muzny DM, Bainbridge MN, Chang K, Dinh HH, Drummond JA, Fowler G, Kovar CL, Lewis LR, Morgan MB, Newsham IF, et al. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012;487:330-7.
-
(2012)
Nature.
, vol.487
, pp. 330-337
-
-
Muzny, D.M.1
Bainbridge, M.N.2
Chang, K.3
Dinh, H.H.4
Drummond, J.A.5
Fowler, G.6
Kovar, C.L.7
Lewis, L.R.8
Morgan, M.B.9
Newsham, I.F.10
-
29
-
-
84907270779
-
Comprehensive molecular characterization of gastric adenocarcinoma
-
Cancer Genome Atlas Research N. Comprehensive molecular characterization of gastric adenocarcinoma. Nature. 2014;513:202-9.
-
(2014)
Nature
, vol.513
, pp. 202-209
-
-
-
30
-
-
84872564830
-
A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
-
Teschendorff AE, Marabita F, Lechner M, Bartlett T, Tegner J, Gomez-Cabrero D, Beck S. A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data. Bioinformatics. 2013;29:189-96.
-
(2013)
Bioinformatics.
, vol.29
, pp. 189-196
-
-
Teschendorff, A.E.1
Marabita, F.2
Lechner, M.3
Bartlett, T.4
Tegner, J.5
Gomez-Cabrero, D.6
Beck, S.7
-
31
-
-
84980386937
-
Computational and Statistical Epigenomics
-
Dordrecht: Springer;
-
Teschendorff A. Computational and Statistical Epigenomics. Dordrecht: Springer; 2015.
-
(2015)
-
-
Teschendorff, A.1
-
32
-
-
84906251108
-
A systems-level integrative framework for genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control
-
Jiao Y, Widschwendter M, Teschendorff AE. A systems-level integrative framework for genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control. Bioinformatics. 2014;30(16):2360-6.
-
(2014)
Bioinformatics.
, vol.30
, Issue.16
, pp. 2360-2366
-
-
Jiao, Y.1
Widschwendter, M.2
Teschendorff, A.E.3
-
33
-
-
84884416048
-
Human housekeeping genes, revisited
-
Eisenberg E, Levanon EY. Human housekeeping genes, revisited. Trends Genet. 2013;29:569-74.
-
(2013)
Trends Genet.
, vol.29
, pp. 569-574
-
-
Eisenberg, E.1
Levanon, E.Y.2
-
34
-
-
70949092295
-
Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice
-
Ye DZ, Kaestner KH. Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice. Gastroenterology. 2009;137:2052-62.
-
(2009)
Gastroenterology.
, vol.137
, pp. 2052-2062
-
-
Ye, D.Z.1
Kaestner, K.H.2
-
35
-
-
84920269464
-
Proteomics. Tissue-based map of the human proteome
-
Uhlen M, Fagerberg L, Hallstrom BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson A, Kampf C, Sjostedt E, Asplund A, et al. Proteomics. Tissue-based map of the human proteome. Science. 2015;347:1260419.
-
(2015)
Science
, vol.347
, pp. 1260419
-
-
Uhlen, M.1
Fagerberg, L.2
Hallstrom, B.M.3
Lindskog, C.4
Oksvold, P.5
Mardinoglu, A.6
Sivertsson, A.7
Kampf, C.8
Sjostedt, E.9
Asplund, A.10
-
36
-
-
0029962261
-
Liver-enriched transcription factors and hepatocyte differentiation
-
Cereghini S. Liver-enriched transcription factors and hepatocyte differentiation. FASEB J. 1996;10:267-82.
-
(1996)
FASEB J.
, vol.10
, pp. 267-282
-
-
Cereghini, S.1
-
37
-
-
84928785787
-
Characterization of the developing small intestine in the absence of either GATA4 or GATA6
-
Walker EM, Thompson CA, Kohlnhofer BM, Faber ML, Battle MA. Characterization of the developing small intestine in the absence of either GATA4 or GATA6. BMC Res Notes. 2014;7:902.
-
(2014)
BMC Res Notes.
, vol.7
, pp. 902
-
-
Walker, E.M.1
Thompson, C.A.2
Kohlnhofer, B.M.3
Faber, M.L.4
Battle, M.A.5
-
38
-
-
84904397909
-
GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development
-
Walker EM, Thompson CA, Battle MA. GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014;392:283-94.
-
(2014)
Dev Biol.
, vol.392
, pp. 283-294
-
-
Walker, E.M.1
Thompson, C.A.2
Battle, M.A.3
-
39
-
-
0242552587
-
GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer
-
Akiyama Y, Watkins N, Suzuki H, Jair KW, van Engeland M, Esteller M, Sakai H, Ren CY, Yuasa Y, Herman JG, Baylin SB. GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer. Mol Cell Biol. 2003;23:8429-39.
-
(2003)
Mol Cell Biol.
, vol.23
, pp. 8429-8439
-
-
Akiyama, Y.1
Watkins, N.2
Suzuki, H.3
Jair, K.W.4
Engeland, M.5
Esteller, M.6
Sakai, H.7
Ren, C.Y.8
Yuasa, Y.9
Herman, J.G.10
Baylin, S.B.11
-
40
-
-
84858785411
-
Regulation of GATA4 transcriptional activity in cardiovascular development and disease
-
Zhou P, He A, Pu WT. Regulation of GATA4 transcriptional activity in cardiovascular development and disease. Curr Top Dev Biol. 2012;100:143-69.
-
(2012)
Curr Top Dev Biol.
, vol.100
, pp. 143-169
-
-
Zhou, P.1
He, A.2
Pu, W.T.3
-
41
-
-
84959288433
-
GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling
-
Xuan S, Sussel L. GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. Development. 2016;143:780-6.
-
(2016)
Development.
, vol.143
, pp. 780-786
-
-
Xuan, S.1
Sussel, L.2
-
42
-
-
84957845905
-
Unique functions of Gata4 in mouse liver induction and heart development
-
Borok MJ, Papaioannou VE, Sussel L. Unique functions of Gata4 in mouse liver induction and heart development. Dev Biol. 2016;410:213-22.
-
(2016)
Dev Biol.
, vol.410
, pp. 213-222
-
-
Borok, M.J.1
Papaioannou, V.E.2
Sussel, L.3
-
43
-
-
79955717831
-
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas
-
Agnihotri S, Wolf A, Munoz DM, Smith CJ, Gajadhar A, Restrepo A, Clarke ID, Fuller GN, Kesari S, Dirks PB, et al. A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas. J Exp Med. 2011;208:689-702.
-
(2011)
J Exp Med.
, vol.208
, pp. 689-702
-
-
Agnihotri, S.1
Wolf, A.2
Munoz, D.M.3
Smith, C.J.4
Gajadhar, A.5
Restrepo, A.6
Clarke, I.D.7
Fuller, G.N.8
Kesari, S.9
Dirks, P.B.10
-
44
-
-
84902903086
-
Developmental lung expression and transcriptional regulation of claudin-6 by TTF-1, Gata-6, and FoxA2
-
Jimenez FR, Lewis JB, Belgique ST, Wood TT, Reynolds PR. Developmental lung expression and transcriptional regulation of claudin-6 by TTF-1, Gata-6, and FoxA2. Respir Res. 2014;15:70.
-
(2014)
Respir Res.
, vol.15
, pp. 70
-
-
Jimenez, F.R.1
Lewis, J.B.2
Belgique, S.T.3
Wood, T.T.4
Reynolds, P.R.5
-
45
-
-
84866174979
-
Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system
-
Arora R, Metzger RJ, Papaioannou VE. Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system. PLoS Genet. 2012;8:e1002866.
-
(2012)
PLoS Genet.
, vol.8
-
-
Arora, R.1
Metzger, R.J.2
Papaioannou, V.E.3
-
46
-
-
84904352123
-
The pleural mesothelium in development and disease
-
Batra H, Antony VB. The pleural mesothelium in development and disease. Front Physiol. 2014;5:284.
-
(2014)
Front Physiol.
, vol.5
, pp. 284
-
-
Batra, H.1
Antony, V.B.2
-
47
-
-
84887449338
-
LHX6 acts as a novel potential tumour suppressor with epigenetic inactivation in lung cancer
-
Liu WB, Jiang X, Han F, Li YH, Chen HQ, Liu Y, Cao J, Liu JY. LHX6 acts as a novel potential tumour suppressor with epigenetic inactivation in lung cancer. Cell Death Dis. 2013;4:e882.
-
(2013)
Cell Death Dis.
, vol.4
-
-
Liu, W.B.1
Jiang, X.2
Han, F.3
Li, Y.H.4
Chen, H.Q.5
Liu, Y.6
Cao, J.7
Liu, J.Y.8
-
48
-
-
60549093206
-
Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct
-
Yu MJ, Miller RL, Uawithya P, Rinschen MM, Khositseth S, Braucht DW, Chou CL, Pisitkun T, Nelson RD, Knepper MA. Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct. Proc Natl Acad Sci U S A. 2009;106:2441-6.
-
(2009)
Proc Natl Acad Sci U S A.
, vol.106
, pp. 2441-2446
-
-
Yu, M.J.1
Miller, R.L.2
Uawithya, P.3
Rinschen, M.M.4
Khositseth, S.5
Braucht, D.W.6
Chou, C.L.7
Pisitkun, T.8
Nelson, R.D.9
Knepper, M.A.10
-
49
-
-
79551615055
-
Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla
-
Berry R, Harewood L, Pei L, Fisher M, Brownstein D, Ross A, Alaynick WA, Moss J, Hastie ND, Hohenstein P, et al. Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla. Hum Mol Genet. 2011;20:917-26.
-
(2011)
Hum Mol Genet.
, vol.20
, pp. 917-926
-
-
Berry, R.1
Harewood, L.2
Pei, L.3
Fisher, M.4
Brownstein, D.5
Ross, A.6
Alaynick, W.A.7
Moss, J.8
Hastie, N.D.9
Hohenstein, P.10
-
50
-
-
84906088790
-
Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers
-
Lam AQ, Freedman BS, Morizane R, Lerou PH, Valerius MT, Bonventre JV. Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers. J Am Soc Nephrol. 2014;25:1211-25.
-
(2014)
J Am Soc Nephrol.
, vol.25
, pp. 1211-1225
-
-
Lam, A.Q.1
Freedman, B.S.2
Morizane, R.3
Lerou, P.H.4
Valerius, M.T.5
Bonventre, J.V.6
-
51
-
-
84857507771
-
A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development
-
Gallegos TF, Kouznetsova V, Kudlicka K, Sweeney DE, Bush KT, Willert K, Farquhar MG, Nigam SK. A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development. Dev Biol. 2012;364:11-21.
-
(2012)
Dev Biol.
, vol.364
, pp. 11-21
-
-
Gallegos, T.F.1
Kouznetsova, V.2
Kudlicka, K.3
Sweeney, D.E.4
Bush, K.T.5
Willert, K.6
Farquhar, M.G.7
Nigam, S.K.8
-
52
-
-
84880696798
-
When urothelial differentiation pathways go wrong: implications for bladder cancer development and progression
-
DeGraff DJ, Cates JM, Mauney JR, Clark PE, Matusik RJ, Adam RM. When urothelial differentiation pathways go wrong: implications for bladder cancer development and progression. Urol Oncol. 2013;31:802-11.
-
(2013)
Urol Oncol.
, vol.31
, pp. 802-811
-
-
DeGraff, D.J.1
Cates, J.M.2
Mauney, J.R.3
Clark, P.E.4
Matusik, R.J.5
Adam, R.M.6
-
53
-
-
57749194878
-
Homeodomain transcription factor CDX1 is required for the transcriptional induction of PPARgamma in intestinal cell differentiation
-
Park MJ, Kim HY, Kim K, Cheong J. Homeodomain transcription factor CDX1 is required for the transcriptional induction of PPARgamma in intestinal cell differentiation. FEBS Lett. 2009;583:29-35.
-
(2009)
FEBS Lett.
, vol.583
, pp. 29-35
-
-
Park, M.J.1
Kim, H.Y.2
Kim, K.3
Cheong, J.4
-
54
-
-
0032737566
-
Cdx1 promotes differentiation in a rat intestinal epithelial cell line
-
Soubeyran P, Andre F, Lissitzky JC, Mallo GV, Moucadel V, Roccabianca M, Rechreche H, Marvaldi J, Dikic I, Dagorn JC, Iovanna JL. Cdx1 promotes differentiation in a rat intestinal epithelial cell line. Gastroenterology. 1999;117:1326-38.
-
(1999)
Gastroenterology.
, vol.117
, pp. 1326-1338
-
-
Soubeyran, P.1
Andre, F.2
Lissitzky, J.C.3
Mallo, G.V.4
Moucadel, V.5
Roccabianca, M.6
Rechreche, H.7
Marvaldi, J.8
Dikic, I.9
Dagorn, J.C.10
Iovanna, J.L.11
-
55
-
-
79251574656
-
Cdx2 levels modulate intestinal epithelium maturity and Paneth cell development
-
Crissey MA, Guo RJ, Funakoshi S, Kong J, Liu J, Lynch JP. Cdx2 levels modulate intestinal epithelium maturity and Paneth cell development. Gastroenterology. 2011;140:517-28. e518.
-
(2011)
Gastroenterology
, vol.140
, pp. 517-528
-
-
Crissey, M.A.1
Guo, R.J.2
Funakoshi, S.3
Kong, J.4
Liu, J.5
Lynch, J.P.6
-
56
-
-
64549114508
-
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2
-
Gao N, White P, Kaestner KH. Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev Cell. 2009;16:588-99.
-
(2009)
Dev Cell.
, vol.16
, pp. 588-599
-
-
Gao, N.1
White, P.2
Kaestner, K.H.3
-
57
-
-
37349015334
-
Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine
-
Desai S, Loomis Z, Pugh-Bernard A, Schrunk J, Doyle MJ, Minic A, McCoy E, Sussel L. Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine. Dev Biol. 2008;313:58-66.
-
(2008)
Dev Biol
, vol.313
, pp. 58-66
-
-
Desai, S.1
Loomis, Z.2
Pugh-Bernard, A.3
Schrunk, J.4
Doyle, M.J.5
Minic, A.6
McCoy, E.7
Sussel, L.8
-
58
-
-
2542446343
-
Minireview: Development and differentiation of gut endocrine cells
-
Schonhoff SE, Giel-Moloney M, Leiter AB. Minireview: Development and differentiation of gut endocrine cells. Endocrinology. 2004;145:2639-44.
-
(2004)
Endocrinology.
, vol.145
, pp. 2639-2644
-
-
Schonhoff, S.E.1
Giel-Moloney, M.2
Leiter, A.B.3
-
59
-
-
84875490185
-
Cancer genome landscapes
-
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz Jr LA, Kinzler KW. Cancer genome landscapes. Science. 2013;339:1546-58.
-
(2013)
Science.
, vol.339
, pp. 1546-1558
-
-
Vogelstein, B.1
Papadopoulos, N.2
Velculescu, V.E.3
Zhou, S.4
Diaz, L.A.5
Kinzler, K.W.6
-
60
-
-
84889021277
-
Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development
-
Jones A, Teschendorff AE, Li Q, Hayward JD, Kannan A, Mould T, West J, Zikan M, Cibula D, Fiegl H, et al. Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development. PLoS Med. 2013;10:e1001551.
-
(2013)
PLoS Med.
, vol.10
-
-
Jones, A.1
Teschendorff, A.E.2
Li, Q.3
Hayward, J.D.4
Kannan, A.5
Mould, T.6
West, J.7
Zikan, M.8
Cibula, D.9
Fiegl, H.10
-
61
-
-
84892690160
-
Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions
-
Feldmann A, Ivanek R, Murr R, Gaidatzis D, Burger L, Schubeler D. Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions. PLoS Genet. 2013;9:e1003994.
-
(2013)
PLoS Genet.
, vol.9
-
-
Feldmann, A.1
Ivanek, R.2
Murr, R.3
Gaidatzis, D.4
Burger, L.5
Schubeler, D.6
-
62
-
-
84956586301
-
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
-
Heyn H, Vidal E, Ferreira HJ, Vizoso M, Sayols S, Gomez A, Moran S, Boque-Sastre R, Guil S, Martinez-Cardus A, et al. Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer. Genome Biol. 2016;17:11.
-
(2016)
Genome Biol.
, vol.17
, pp. 11
-
-
Heyn, H.1
Vidal, E.2
Ferreira, H.J.3
Vizoso, M.4
Sayols, S.5
Gomez, A.6
Moran, S.7
Boque-Sastre, R.8
Guil, S.9
Martinez-Cardus, A.10
-
63
-
-
51649083501
-
A microRNA DNA methylation signature for human cancer metastasis
-
Lujambio A, Calin GA, Villanueva A, Ropero S, Sanchez-Cespedes M, Blanco D, Montuenga LM, Rossi S, Nicoloso MS, Faller WJ, et al. A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci U S A. 2008;105:13556-61.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, pp. 13556-13561
-
-
Lujambio, A.1
Calin, G.A.2
Villanueva, A.3
Ropero, S.4
Sanchez-Cespedes, M.5
Blanco, D.6
Montuenga, L.M.7
Rossi, S.8
Nicoloso, M.S.9
Faller, W.J.10
-
64
-
-
37549024511
-
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
-
Blenkiron C, Goldstein LD, Thorne NP, Spiteri I, Chin SF, Dunning MJ, Barbosa-Morais NL, Teschendorff AE, Green AR, Ellis IO, et al. MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol. 2007;8:R214.
-
(2007)
Genome Biol.
, vol.8
, pp. R214
-
-
Blenkiron, C.1
Goldstein, L.D.2
Thorne, N.P.3
Spiteri, I.4
Chin, S.F.5
Dunning, M.J.6
Barbosa-Morais, N.L.7
Teschendorff, A.E.8
Green, A.R.9
Ellis, I.O.10
-
65
-
-
81055154928
-
Bivalent histone modifications in stem cells poise miRNA loci for CpG island hypermethylation in human cancer
-
Iliou MS, Lujambio A, Portela A, Brustle O, Koch P, Andersson-Vincent PH, Sundstrom E, Hovatta O, Esteller M. Bivalent histone modifications in stem cells poise miRNA loci for CpG island hypermethylation in human cancer. Epigenetics. 2011;6(11):1344-53.
-
(2011)
Epigenetics.
, vol.6
, Issue.11
, pp. 1344-1353
-
-
Iliou, M.S.1
Lujambio, A.2
Portela, A.3
Brustle, O.4
Koch, P.5
Andersson-Vincent, P.H.6
Sundstrom, E.7
Hovatta, O.8
Esteller, M.9
-
66
-
-
84912090582
-
IDH mutations in liver cell plasticity and biliary cancer
-
Saha SK, Parachoniak CA, Bardeesy N. IDH mutations in liver cell plasticity and biliary cancer. Cell Cycle. 2014;13:3176-82.
-
(2014)
Cell Cycle.
, vol.13
, pp. 3176-3182
-
-
Saha, S.K.1
Parachoniak, C.A.2
Bardeesy, N.3
-
67
-
-
84961357451
-
DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer
-
Teschendorff AE, Gao Y, Jones A, Ruebner M, Beckmann MW, Wachter DL, Fasching PA, Widschwendter M. DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer. Nat Commun. 2016;7:10478.
-
(2016)
Nat Commun.
, vol.7
, pp. 10478
-
-
Teschendorff, A.E.1
Gao, Y.2
Jones, A.3
Ruebner, M.4
Beckmann, M.W.5
Wachter, D.L.6
Fasching, P.A.7
Widschwendter, M.8
-
68
-
-
77956873627
-
Tackling the widespread and critical impact of batch effects in high-throughput data
-
Leek JT, Scharpf RB, Bravo HC, Simcha D, Langmead B, Johnson WE, Geman D, Baggerly K, Irizarry RA. Tackling the widespread and critical impact of batch effects in high-throughput data. Nat Rev Genet. 2010;11:733-9.
-
(2010)
Nat Rev Genet.
, vol.11
, pp. 733-739
-
-
Leek, J.T.1
Scharpf, R.B.2
Bravo, H.C.3
Simcha, D.4
Langmead, B.5
Johnson, W.E.6
Geman, D.7
Baggerly, K.8
Irizarry, R.A.9
-
69
-
-
84977570870
-
A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2
-
Yang S, He P, Wang J, Schetter A, Tang W, Funamizu N, Yanaga K, Uwagawa T, Satoskar AR, Gaedcke J, et al. A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2. Cancer Res. 2016;76(13):3838-50.
-
(2016)
Cancer Res.
, vol.76
, Issue.13
, pp. 3838-3850
-
-
Yang, S.1
He, P.2
Wang, J.3
Schetter, A.4
Tang, W.5
Funamizu, N.6
Yanaga, K.7
Uwagawa, T.8
Satoskar, A.R.9
Gaedcke, J.10
-
70
-
-
32244435895
-
Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer
-
Smith LT, Lin M, Brena RM, Lang JC, Schuller DE, Otterson GA, Morrison CD, Smiraglia DJ, Plass C. Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer. Proc Natl Acad Sci U S A. 2006;103:982-7.
-
(2006)
Proc Natl Acad Sci U S A.
, vol.103
, pp. 982-987
-
-
Smith, L.T.1
Lin, M.2
Brena, R.M.3
Lang, J.C.4
Schuller, D.E.5
Otterson, G.A.6
Morrison, C.D.7
Smiraglia, D.J.8
Plass, C.9
-
71
-
-
84898057938
-
Loss of BRM expression is a frequently observed event in poorly differentiated clear cell renal cell carcinoma
-
Xia QY, Rao Q, Cheng L, Shen Q, Shi SS, Li L, Liu B, Zhang J, Wang YF, Shi QL, et al. Loss of BRM expression is a frequently observed event in poorly differentiated clear cell renal cell carcinoma. Histopathology. 2014;64:847-62.
-
(2014)
Histopathology.
, vol.64
, pp. 847-862
-
-
Xia, Q.Y.1
Rao, Q.2
Cheng, L.3
Shen, Q.4
Shi, S.S.5
Li, L.6
Liu, B.7
Zhang, J.8
Wang, Y.F.9
Shi, Q.L.10
-
72
-
-
84930753236
-
Frequent co-inactivation of the SWI/SNF subunits SMARCB1, SMARCA2 and PBRM1 in malignant rhabdoid tumours
-
Rao Q, Xia QY, Wang ZY, Li L, Shen Q, Shi SS, Wang X, Liu B, Wang YF, Shi QL, et al. Frequent co-inactivation of the SWI/SNF subunits SMARCB1, SMARCA2 and PBRM1 in malignant rhabdoid tumours. Histopathology. 2015;67:121-9.
-
(2015)
Histopathology.
, vol.67
, pp. 121-129
-
-
Rao, Q.1
Xia, Q.Y.2
Wang, Z.Y.3
Li, L.4
Shen, Q.5
Shi, S.S.6
Wang, X.7
Liu, B.8
Wang, Y.F.9
Shi, Q.L.10
-
73
-
-
84895070874
-
Identifying targets for the restoration and reactivation of BRM
-
Kahali B, Gramling SJ, Marquez SB, Thompson K, Lu L, Reisman D. Identifying targets for the restoration and reactivation of BRM. Oncogene. 2014;33:653-64.
-
(2014)
Oncogene.
, vol.33
, pp. 653-664
-
-
Kahali, B.1
Gramling, S.J.2
Marquez, S.B.3
Thompson, K.4
Lu, L.5
Reisman, D.6
-
74
-
-
84871988651
-
Recurrent SETBP1 mutations in atypical chronic myeloid leukemia
-
Piazza R, Valletta S, Winkelmann N, Redaelli S, Spinelli R, Pirola A, Antolini L, Mologni L, Donadoni C, Papaemmanuil E, et al. Recurrent SETBP1 mutations in atypical chronic myeloid leukemia. Nat Genet. 2013;45:18-24.
-
(2013)
Nat Genet.
, vol.45
, pp. 18-24
-
-
Piazza, R.1
Valletta, S.2
Winkelmann, N.3
Redaelli, S.4
Spinelli, R.5
Pirola, A.6
Antolini, L.7
Mologni, L.8
Donadoni, C.9
Papaemmanuil, E.10
-
75
-
-
84880976662
-
Somatic SETBP1 mutations in myeloid malignancies
-
Makishima H, Yoshida K, Nguyen N, Przychodzen B, Sanada M, Okuno Y, Ng KP, Gudmundsson KO, Vishwakarma BA, Jerez A, et al. Somatic SETBP1 mutations in myeloid malignancies. Nat Genet. 2013;45:942-6.
-
(2013)
Nat Genet.
, vol.45
, pp. 942-946
-
-
Makishima, H.1
Yoshida, K.2
Nguyen, N.3
Przychodzen, B.4
Sanada, M.5
Okuno, Y.6
Ng, K.P.7
Gudmundsson, K.O.8
Vishwakarma, B.A.9
Jerez, A.10
|