A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2

Cancer Research

Volumn 76, Issue 13, 2016, Pages 3838-3850

  Yang, Shouhui ^a   He, Peijun ^a   Wang, Jian ^a   Schetter, Aaron ^a   Tang, Wei ^a   Funamizu, Naotake ^b   Yanaga, Katsuhiko ^b   Uwagawa, Tadashi ^b   Satoskar, Abhay R ^c   Gaedcke, Jochen ^d   Bernhardt, Markus ^d   Ghadimi, B Michael ^d   Gaida, Matthias M ^e   Bergmann, Frank ^e   Werner, Jens ^f   Ried, Thomas ^a   Hanna, Nader ^g   Alexander, H Richard ^g   Hussain, S Perwez ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c OHIO STATE UNIVERSITY   (United States)

^d UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^e UNIVERSITY OF HEIDELBERG   (Germany)

^f LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^g UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GEMCITABINE; MACROPHAGE MIGRATION INHIBITION FACTOR; MICRORNA; MICRORNA 10B; MICRORNA 15B; MICRORNA 301B; MICRORNA 590; MICRORNA 93; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; NUCLEAR RECEPTOR NR3C2; ORPHAN NUCLEAR RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR ZEB1; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; ISOMERASE; MIF PROTEIN, HUMAN; MINERALOCORTICOID RECEPTOR; NR3C2 PROTEIN, HUMAN; TUMOR MARKER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PROGNOSIS; CANCER SURVIVAL; CARCINOGENESIS; CHEMOSENSITIVITY; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MODEL; DRUG TARGETING; EPITHELIAL MESENCHYMAL TRANSITION; GENE DELETION; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ENGINEERING; GENETIC LINKAGE; HUMAN; HUMAN CELL; INHIBITION KINETICS; METASTASIS INHIBITION; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SURVIVAL RATE; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; CANCER STAGING; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PANCREAS CARCINOMA; PANCREATIC NEOPLASMS; PATHOLOGY; PROGNOSIS; TUMOR CELL CULTURE;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BIOMARKERS, TUMOR; CARCINOMA, PANCREATIC DUCTAL; CELL MOVEMENT; CELL PROLIFERATION; DEOXYCYTIDINE; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MICE; MICE, KNOCKOUT; MICRORNAS; NEOPLASM STAGING; PANCREATIC NEOPLASMS; PROGNOSIS; RECEPTORS, MINERALOCORTICOID; SIGNAL TRANSDUCTION; SURVIVAL RATE; TUMOR CELLS, CULTURED;

EID: 84977570870     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-2841     Document Type: Article

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