Characterization of the developing small intestine in the absence of either GATA4 or GATA6

BMC Research Notes

Volumn 7, Issue 1, 2014, Pages

  Walker, Emily M ^a   Thompson, Cayla A ^a   Kohlnhofer, Bridget M ^a   Faber, Mary L ^a   Battle, Michele A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Conditional knockout; Development; Epithelium; GATA4; GATA6; Small intestine

Indexed keywords

GATA4 PROTEIN, MOUSE; GATA6 PROTEIN, MOUSE; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6;

ANIMAL; GROWTH, DEVELOPMENT AND AGING; KNOCKOUT MOUSE; METABOLISM; MOUSE; SMALL INTESTINE;

ANIMALS; GATA4 TRANSCRIPTION FACTOR; GATA6 TRANSCRIPTION FACTOR; INTESTINE, SMALL; MICE; MICE, KNOCKOUT;

EID: 84928785787     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/1756-0500-7-902     Document Type: Article

References (23)

1. Battle MA, Bondow BJ, Iverson MA, Adams SJ, Jandacek RJ, Tso P, Duncan SA: GATA4 Is Essential for Jejunal Function in Mice. Gastroenterology 2008, 135:1676-1686.e1.
2. Beuling E, Baffour-Awuah NY, Stapleton KA, Aronson BE, Noah TK, Shroyer NF, Duncan SA, Fleet JC, Krasinski SD: GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice. Gastroenterology 2011, 140:1219-1229.e1.
3. Bosse T, Fialkovich JJ, Piaseckyj CM, Beuling E, Broekman H, Grand RJ, Montgomery RK, Krasinski SD: Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol 2007, 292:G1302-G1314.
4. Bosse T, Piaseckyj CM, Burghard E, Fialkovich JJ, Rajagopal S, Pu WT, Krasinski SD: Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine. Mol Cell Biol 2006, 26:9060-9070.
5. Koutsourakis M, Langeveld A, Patient R, Beddington R, Grosveld F: The transcription factor GATA6 is essential for early extraembryonic development. Development 1999, 126:723-732.
6. Molkentin JD: The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J Biol Chem 2000, 275:38949-38952.
7. Watt AJ, Zhao R, Li J, Duncan SA: Development of the mammalian liver and ventral pancreas is dependent on GATA4. BMC Dev Biol 2007, 7:37.
8. Fang R, Olds LC, Sibley E: Spatio-temporal patterns of intestine-specific transcription factor expression during postnatal mouse gut development. Gene Expr Patterns 2006, 6:426-432.
9. Kuo CT, Morrisey EE, Anandappa R, Sigrist K, Lu MM, Parmacek MS, Soudais C, Leiden JM: GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev 1997, 11:1048-1060.
10. Molkentin JD, Lin Q, Duncan SA, Olson EN: Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev 1997, 11:1061-1072.
11. Morrisey EE, Tang Z, Sigrist K, Lu MM, Jiang F, Ip HS, Parmacek MS: GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev 1998, 12:3579-3590.
12. Walker EM, Thompson CA, Battle MA: GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol 2014, 392:283-294.
13. Madison BB, Dunbar L, Qiao XT, Braunstein K, Braunstein E, Gumucio DL: Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J Biol Chem 2002, 277:33275-33283.
14. Sodhi CP, Li J, Duncan SA: Generation of mice harbouring a conditional loss-of-function allele of Gata6. BMC Dev Biol 2006, 6:19.
15. Watt AJ, Battle MA, Li J, Duncan SA: GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc Natl Acad Sci U S A 2004, 101:12573-12578.
16. Soriano P: Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999, 21:70-71.
17. Thompson CA, Battle MA: Basic Science of Small Intestinal Development, Translational Research and Discovery in Gastroenterology: Organogenesis to Disease. 2014:85.
18. Lev R, Griffiths WC: Colonic and small intestinal alkaline phosphatase. A histochemical and biochemical study. Gastroenterology 1982, 82:1427-1435.
19. Bondow BJ, Faber ML, Wojta KJ, Walker EM, Battle MA: E-cadherin is required for intestinal morphogenesis in the mouse. Dev Biol 2012, 371:1-12.
20. Li X, Madison BB, Zacharias W, Kolterud A, States D, Gumucio DL: Deconvoluting the intestine: molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk. Physiol Genomics 2007, 29:290-301.
21. Madison BB, Braunstein K, Kuizon E, Portman K, Qiao XT, Gumucio DL: Epithelial hedgehog signals pattern the intestinal crypt-villus axis. Development 2005, 132:279-289.
22. Duncan SA, Nagy A, Chan W: Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryos. Development 1997, 124:279-287.
23. Hogan B, Beddington R, Costantini F, Lacy E: Manipulating the Mouse Embryo: A Laboratory Manual, Hogan Manipulating the Mouse Embryo: A Laboratory Manual1994. Plainview, NY: ColdSpring Harbor Lab. Press; 1994.