SNAP-Tag Technology: A Useful Tool to Determine Affinity Constants and Other Functional Parameters of Novel Antibody Fragments

Bioconjugate Chemistry

Volumn 27, Issue 8, 2016, Pages 1931-1941

  Niesen, Judith ^a   Sack, Markus ^b   Seidel, Melanie ^a   Fendel, Rolf ^a   Barth, Stefan ^a   Fischer, Rainer ^a,b   Stein, Christoph ^a  

^a FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; CHEMICAL MODIFICATION; DIAGNOSIS; SURFACE PLASMON RESONANCE;

AFFINITY CONSTANTS; ANTIBODY-FRAGMENT; CANCER RESEARCH; CHAIN FRAGMENTS; DIAGNOSTICS TOOLS; FUNCTIONAL PARAMETERS; FUSION PROTEINS; SINGLE CHAINS; SURFACE PLASMON RESONANCE SPECTROSCOPY; THERAPEUTIC TOOLS;

MONOCLONAL ANTIBODIES;

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; CETUXIMAB; DNA LIGASE; EPIDERMAL GROWTH FACTOR RECEPTOR; HYBRID PROTEIN; IMMOBILIZED PROTEIN; PANITUMUMAB; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TUMOR ANTIGEN; MONOCLONAL ANTIBODY;

ANTIBODY AFFINITY; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CANCER PATIENT; CELL SURFACE; CLINICAL EVALUATION; COMPETITIVE INHIBITION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA REPAIR; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL TEST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISOTHERMAL TITRATION CALORIMETRY; PROTEIN MODIFICATION; SOLID TUMOR; SURFACE PLASMON RESONANCE; CHEMISTRY; METABOLISM; TUMOR CELL LINE;

ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; HUMANS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SINGLE-CHAIN ANTIBODIES;

EID: 84983541852     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/acs.bioconjchem.6b00315     Document Type: Article

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