Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy

Critical Reviews in Oncology/Hematology

Volumn 38, Issue 1, 2001, Pages 17-23

  Yang, Xiao Dong ^a   Jia, Xiao Chi ^a   Corvalan, Jose R F ^a   Wang, Ping ^a   Davis, C Geoffrey ^a  

^a Abgenix Inc   (United States)

Author keywords

Cancer therapy; EGFr; Human monoclonal antibody; XenoMouse

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; IMMUNOGLOBULIN G2; MONOCLONAL ANTIBODY; PANITUMUMAB; TRANSFORMING GROWTH FACTOR ALPHA; TRASTUZUMAB; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL MODEL; ANTIBODY SPECIFICITY; BINDING AFFINITY; BINDING COMPETITION; BIOTECHNOLOGY; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CANCER RECURRENCE; CANCER THERAPY; CELL DEATH; CELL PROLIFERATION; CLINICAL TRIAL; EXTRACELLULAR FLUID; HUMAN; KIDNEY CANCER; METASTASIS; MOUSE; NONHUMAN; NUDE MOUSE; PANCREAS CANCER; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; REVIEW; SOLID TUMOR; SQUAMOUS CELL CARCINOMA; TUMOR; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, HETEROPHILE; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; EPIDERMAL GROWTH FACTOR; HUMANS; MICE; NEOPLASMS;

EID: 0035117355     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1040-8428(00)00134-7     Document Type: Review

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