High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays

Analytical Biochemistry

Volumn 351, Issue 2, 2006, Pages 241-253

  Wassaf, Dina ^a   Kuang, Guannan ^a   Kopacz, Kris ^a   Wu, Qi Long ^a   Nguyen, Que ^a   Toews, Mark ^a   Cosic, Janja ^a   Jacques, Judith ^a   Wiltshire, Steve ^b,d   Lambert, Jeremy ^c   Pazmany, Csaba C ^a   Hogan, Shannon ^a   Ladner, Robert C ^a   Nixon, Andrew E ^a   Sexton, Daniel J ^a  

^a Dyax Corp   (United States)

^b HTS Biosystems   (United States)

^c PHYNEXUS INC   (United States)

^d CHARLES RIVER LABORATORIES   (United States)

Author keywords

Antibody arrays; Antibody inhibitors; Antibody phage display; Kallikrein; Serine protease; Surface plasmon resonance

Indexed keywords

AMINO ACIDS; ANTIBODIES; BIOASSAY; DISSOCIATION; ESCHERICHIA COLI; PHAGE DISPLAY; PLASMONS; PURIFICATION; RESONANCE;

ANTIBODY ARRAYS; DISSOCIATION CONSTANT; HIGH THROUGHPUT; HIGH-AFFINITY HUMAN ANTIBODIES; KALLIKREIN; KINETIC CONSTANT; PHAGE DISPLAY LIBRARIES; SERINE PROTEASE;

SURFACE PLASMON RESONANCE;

EPITOPE; GENE PRODUCT; IMMUNOGLOBULIN F(AB) FRAGMENT; KALLIKREIN;

ANTIBODY AFFINITY; ARTICLE; BINDING SITE; DISSOCIATION CONSTANT; ESCHERICHIA COLI; HIGH THROUGHPUT SCREENING; HUMAN; KINETICS; MICROARRAY ANALYSIS; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SURFACE PLASMON RESONANCE;

ESCHERICHIA COLI;

EID: 33645305964     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2006.01.043     Document Type: Article

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