SNAP-tag based agents for preclinical In Vitro imaging in malignant diseases

Current Pharmaceutical Design

Volumn 19, Issue 30, 2013, Pages 5429-5436

  Amoury, Manal ^a   Blume, Tobias ^a   Brehm, Hannes ^a   Niesen, Judith ^b   Tenhaef, Niklas ^a   Barth, Stefan ^a,c   Gattenlöhner, Stefan ^d   Helfrich, Wijnand ^e   Fitting, Jenny ^a   Nachreiner, Thomas ^a   Pardo, Alessa ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b Pharmedartis   (Germany)

^c FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^d UNIVERSITY HOSPITAL GIESSEN   (Germany)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Molecular imaging; Protein therapeutics; Receptor mediated internalization; Single chain fragment variable (scFv); SNAP tag technology

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; ANTINEOPLASTIC AGENT; BENZYLGUANINE DERIVATIVE; FLUORESCENT DYE; GUANINE DERIVATIVE; HYBRID PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY 35; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY 35 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE FUSION PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY C54; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY C54 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE FUSION PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY CD38; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY CD38 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE FUSION PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY D7; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY D7 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE FUSION PROTEIN; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CARCINOMA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG BINDING; DRUG SCREENING; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; LYMPHATIC SYSTEM TUMOR; MALIGNANT NEOPLASTIC DISEASE; MOLECULAR IMAGING; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; RHABDOMYOSARCOMA;

ANIMALS; ANTIBODIES; ANTINEOPLASTIC AGENTS; CLONING, MOLECULAR; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; MICE; MOLECULAR IMAGING; NEOPLASMS; PROTEIN BINDING;

EID: 84881327577     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/13816128113199990405     Document Type: Article

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