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Volumn 39, Issue 16, 2016, Pages 3113-3122

Fast and comprehensive analysis of secondary metabolites in cocoa products using ultra high-performance liquid chromatography directly after pressurized liquid extraction

Author keywords

Chocolate; Cocoa; Flavanols; Liquid chromatography; Pressurized liquid extraction

Indexed keywords

AMINO ACIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; COCOA; FLAVONOIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LIQUIDS; METABOLITES; ORGANIC ACIDS;

EID: 84983446378     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201600422     Document Type: Article
Times cited : (15)

References (53)
  • 1
    • 84857892715 scopus 로고    scopus 로고
    • Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials
    • Hooper, L., Kay, C., Abdelhamid, A., Kroon, P. A., Cohn, J. S., Rimm, E. B., Cassidy, A. Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. Am. J. Clin. Nutr. 2012, 95, 740–751.
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 740-751
    • Hooper, L.1    Kay, C.2    Abdelhamid, A.3    Kroon, P.A.4    Cohn, J.S.5    Rimm, E.B.6    Cassidy, A.7
  • 3
    • 33646072996 scopus 로고    scopus 로고
    • Chocolate and prevention of cardiovascular disease: a systematic review
    • Ding, E. L., Hutfless, S. M., Ding, X., Girotra, S. Chocolate and prevention of cardiovascular disease: a systematic review. Nutr. Metabolism 2006, 3, 1–12.
    • (2006) Nutr. Metabolism , vol.3 , pp. 1-12
    • Ding, E.L.1    Hutfless, S.M.2    Ding, X.3    Girotra, S.4
  • 5
    • 84861559254 scopus 로고    scopus 로고
    • Epicatechin ingested via cocoa products reduces blood pressure in humans: a nonlinear regression model with a Bayesian approach
    • Ellinger, S., Reusch, A., Stehle, P., Helfrich, H.-P. Epicatechin ingested via cocoa products reduces blood pressure in humans: a nonlinear regression model with a Bayesian approach. Am J. Clin. Nutr. 2012, 95, 1365–1377.
    • (2012) Am J. Clin. Nutr. , vol.95 , pp. 1365-1377
    • Ellinger, S.1    Reusch, A.2    Stehle, P.3    Helfrich, H.-P.4
  • 6
    • 34347404130 scopus 로고    scopus 로고
    • Effects of low habitual cocoa intake on blood pressure and bioactive nitric oxide: a randomized controlled trial
    • Taubert, D., Roesen, R., Lehmann, C., Jung, N., Schömig, E. Effects of low habitual cocoa intake on blood pressure and bioactive nitric oxide: a randomized controlled trial. JAMA 2007, 298, 49–60.
    • (2007) JAMA , vol.298 , pp. 49-60
    • Taubert, D.1    Roesen, R.2    Lehmann, C.3    Jung, N.4    Schömig, E.5
  • 7
    • 37349101576 scopus 로고    scopus 로고
    • Cocoa and health: a decade of research
    • Cooper, K. A., Donovan, J. L. Cocoa and health: a decade of research. Br. J. Nutr. 2008, 99, 1–11.
    • (2008) Br. J. Nutr. , vol.99 , pp. 1-11
    • Cooper, K.A.1    Donovan, J.L.2
  • 8
    • 84983431652 scopus 로고    scopus 로고
    • Official Journal of the European Union
    • Regulation (EC) No 1924/2006. Official Journal of the European Union 2016, L 404, 9–25.
    • (2016) , vol.404 , pp. 9-25
  • 9
    • 84983440972 scopus 로고    scopus 로고
    • Official Journal of the European Union
    • Commission Regulation (EU) No 851/2013. Official Journal of the European Union 2013, L 235, 3–7.
    • (2013) , vol.L 235 , pp. 3-7
  • 10
    • 77952094543 scopus 로고    scopus 로고
    • Differences between the content of phenolic compounds in Criollo, Forastero and Trinitario cocoa seed (Theobroma cacao L.)
    • Elwers, S., Zambrano, A., Rohsius, C. Differences between the content of phenolic compounds in Criollo, Forastero and Trinitario cocoa seed (Theobroma cacao L.). Eur. Food Res. Technol. 2009, 229, 937–948.
    • (2009) Eur. Food Res. Technol. , vol.229 , pp. 937-948
    • Elwers, S.1    Zambrano, A.2    Rohsius, C.3
  • 11
    • 78049281488 scopus 로고    scopus 로고
    • Impact of fermentation, drying, roasting, and Dutch processing on epicatechin and catechin content of cacao beans and cocoa ingredients
    • Payne, M. J., Hurst, W. J., Miller, K. B., Rank, C., Stuart, D. A. Impact of fermentation, drying, roasting, and Dutch processing on epicatechin and catechin content of cacao beans and cocoa ingredients. J. Agric. Food Chem. 2010, 58, 10518–10527.
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 10518-10527
    • Payne, M.J.1    Hurst, W.J.2    Miller, K.B.3    Rank, C.4    Stuart, D.A.5
  • 13
    • 77951258383 scopus 로고    scopus 로고
    • Chiral separation of (+)/(−)-catechin from sulfated and glucuronidated metabolites in human plasma after cocoa consumption
    • Ritter, C., Zimmermann, B. F., Galensa, R. Chiral separation of (+)/(−)-catechin from sulfated and glucuronidated metabolites in human plasma after cocoa consumption. Anal. Bioanal. Chem. 2010, 397, 723–730.
    • (2010) Anal. Bioanal. Chem. , vol.397 , pp. 723-730
    • Ritter, C.1    Zimmermann, B.F.2    Galensa, R.3
  • 14
    • 34547633460 scopus 로고    scopus 로고
    • (−)-Catechin in cocoa and chocolate: occurence and analysis of an atypical flavan-3-ol enantiomer
    • Kofink, M., Papagiannopoulos, M., Galensa, R. (−)-Catechin in cocoa and chocolate: occurence and analysis of an atypical flavan-3-ol enantiomer. Molecules 2007, 12, 1274–1288.
    • (2007) Molecules , vol.12 , pp. 1274-1288
    • Kofink, M.1    Papagiannopoulos, M.2    Galensa, R.3
  • 15
    • 79961135621 scopus 로고    scopus 로고
    • Flavanols and methylxanthines in commercially available dark chocolate: a study of the correlation with nonfat cocoa solids
    • Langer, S., Marshall, L. J., Day, A. J., Morgan, M. R. A. Flavanols and methylxanthines in commercially available dark chocolate: a study of the correlation with nonfat cocoa solids. J. Agric. Food Chem. 2011, 59, 8435–8441.
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 8435-8441
    • Langer, S.1    Marshall, L.J.2    Day, A.J.3    Morgan, M.R.A.4
  • 16
    • 0033946356 scopus 로고    scopus 로고
    • Review on polyphenols in Theobroma cacao: changes in composition during the manufacture of chocolate and methodology for identification and quantification
    • Wollgast, J., Anklam, E. Review on polyphenols in Theobroma cacao: changes in composition during the manufacture of chocolate and methodology for identification and quantification. Food Res. Int. 2000, 33, 423–447.
    • (2000) Food Res. Int. , vol.33 , pp. 423-447
    • Wollgast, J.1    Anklam, E.2
  • 17
    • 0037077367 scopus 로고    scopus 로고
    • Extraction of methylxanthines from guaraná seeds, maté leaves, and cocoa beans using supercritical carbon dioxide and ethanol
    • Saldaña, M. D. A., Zetzl, C., Mohamed, R. S., Brunner, G. Extraction of methylxanthines from guaraná seeds, maté leaves, and cocoa beans using supercritical carbon dioxide and ethanol. J. Agric. Food Chem. 2002, 50, 4820–4826.
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 4820-4826
    • Saldaña, M.D.A.1    Zetzl, C.2    Mohamed, R.S.3    Brunner, G.4
  • 18
    • 67349136357 scopus 로고    scopus 로고
    • Comparative study of commercially available cocoa products in terms of their bioactive composition
    • Belščak, A., Komes, D., Horžić, D., Ganić, K. K., Karlović, D. Comparative study of commercially available cocoa products in terms of their bioactive composition. Food Res. Int. 2009, 42, 707–716.
    • (2009) Food Res. Int. , vol.42 , pp. 707-716
    • Belščak, A.1    Komes, D.2    Horžić, D.3    Ganić, K.K.4    Karlović, D.5
  • 19
    • 0037035816 scopus 로고    scopus 로고
    • Online coupling of pressurized liquid extraction, solid-phase extraction and high-performance liquid chromatography for automated analysis of proanthocyanidins in malt
    • Papagiannopoulos, M., Zimmermann, B., Mellenthin, A., Krappe, M., Maio, G., Galensa, R. Online coupling of pressurized liquid extraction, solid-phase extraction and high-performance liquid chromatography for automated analysis of proanthocyanidins in malt. J. Chromatogr. A 2002, 958, 9–16.
    • (2002) J. Chromatogr. A , vol.958 , pp. 9-16
    • Papagiannopoulos, M.1    Zimmermann, B.2    Mellenthin, A.3    Krappe, M.4    Maio, G.5    Galensa, R.6
  • 21
    • 80051691315 scopus 로고    scopus 로고
    • Pressurized liquid extraction as a green approach in food and herbal plants extraction: a review
    • Mustafa, A., Turner, C. Pressurized liquid extraction as a green approach in food and herbal plants extraction: a review. Anal. Chim. Acta 2011, 703, 8–18.
    • (2011) Anal. Chim. Acta , vol.703 , pp. 8-18
    • Mustafa, A.1    Turner, C.2
  • 22
    • 0037044638 scopus 로고    scopus 로고
    • Automated sample preparation by pressurized liquid extraction-solid-phase extraction for the liquid chromatographic-mass spectrometric investigation of polyphenols in the brewing process
    • Papagiannopoulos, M., Mellenthin, A. Automated sample preparation by pressurized liquid extraction-solid-phase extraction for the liquid chromatographic-mass spectrometric investigation of polyphenols in the brewing process. J. Chromatogr. A 2002, 976, 345–348.
    • (2002) J. Chromatogr. A , vol.976 , pp. 345-348
    • Papagiannopoulos, M.1    Mellenthin, A.2
  • 23
    • 2942528726 scopus 로고    scopus 로고
    • Identification and quantification of polyphenols in carob fruits (Ceratonia siliqua L.) and derived products by HPLC-UV-ESI/MSn
    • Papagiannopoulos, M., Wollseifen, H., Mellenthin, A., Haber, B., Galensa, R. Identification and quantification of polyphenols in carob fruits (Ceratonia siliqua L.) and derived products by HPLC-UV-ESI/MSn. J. Agric. Food Chem. 2004, 52, 3784–3791.
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 3784-3791
    • Papagiannopoulos, M.1    Wollseifen, H.2    Mellenthin, A.3    Haber, B.4    Galensa, R.5
  • 24
    • 84866645341 scopus 로고    scopus 로고
    • Comparing procyanidins in selected Vaccinium species by UHPLC-MS2 with regard to authenticity and health effects
    • Jungfer, E., Zimmermann, B. F., Ruttkat, A., Galensa, R. Comparing procyanidins in selected Vaccinium species by UHPLC-MS2 with regard to authenticity and health effects. J. Agric. Food Chem. 2012, 60, 9688–9696.
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 9688-9696
    • Jungfer, E.1    Zimmermann, B.F.2    Ruttkat, A.3    Galensa, R.4
  • 25
    • 37749032775 scopus 로고    scopus 로고
    • A rapid method for simultaneous determination of 15 flavonoids in Epimedium using pressurized liquid extraction and ultra-performance liquid chromatography
    • Chen, X. J., Ji, H., Zhang, Q. W., Tu, P. F., Wang, Y. T., Guo, B. L., Li, S. P. A rapid method for simultaneous determination of 15 flavonoids in Epimedium using pressurized liquid extraction and ultra-performance liquid chromatography. J. Pharmaceut. Biomed. 2008, 46, 226–235.
    • (2008) J. Pharmaceut. Biomed. , vol.46 , pp. 226-235
    • Chen, X.J.1    Ji, H.2    Zhang, Q.W.3    Tu, P.F.4    Wang, Y.T.5    Guo, B.L.6    Li, S.P.7
  • 26
    • 22044435386 scopus 로고    scopus 로고
    • Pressurized liquid extraction-capillary electrophoresis-mass spectrometry for the analysis of polar antioxidants in rosemary extracts
    • Herrero, M., Arraez-Roman, D., Segura, A., Kenndler, E., Gius, B., Raggi, M., Ibanez, E., Cifuentes, A. Pressurized liquid extraction-capillary electrophoresis-mass spectrometry for the analysis of polar antioxidants in rosemary extracts. J. Chromatogr. A 2005, 1084, 54–62.
    • (2005) J. Chromatogr. A , vol.1084 , pp. 54-62
    • Herrero, M.1    Arraez-Roman, D.2    Segura, A.3    Kenndler, E.4    Gius, B.5    Raggi, M.6    Ibanez, E.7    Cifuentes, A.8
  • 27
    • 70349236885 scopus 로고    scopus 로고
    • Pressurised liquid extraction of flavonoids in onions. Method Development and Validation
    • Soltoft, M., Christensen, J. H., Nielsen, J., Knuthsen, P. Pressurised liquid extraction of flavonoids in onions. Method Development and Validation. Talanta 2009, 80, 269–278.
    • (2009) Talanta , vol.80 , pp. 269-278
    • Soltoft, M.1    Christensen, J.H.2    Nielsen, J.3    Knuthsen, P.4
  • 28
    • 84884564067 scopus 로고    scopus 로고
    • Temperature influences epimerization and composition of flavanol monomers, dimers and trimers during cocoa bean roasting
    • Kothe, L., Zimmermann, B. F., Galensa, R. Temperature influences epimerization and composition of flavanol monomers, dimers and trimers during cocoa bean roasting. Food Chem. 2013, 141, 3656–3663.
    • (2013) Food Chem , vol.141 , pp. 3656-3663
    • Kothe, L.1    Zimmermann, B.F.2    Galensa, R.3
  • 30
    • 77957682023 scopus 로고    scopus 로고
    • High throughput qualitative analysis of polyphenols in tea samples by ultra-high pressure liquid chromatography coupled to UV and mass spectrometry detectors
    • Guillarme, D., Casetta, C., Bicchi, C., Veuthey, J.-L. High throughput qualitative analysis of polyphenols in tea samples by ultra-high pressure liquid chromatography coupled to UV and mass spectrometry detectors. J. Chromatogr. A 2010, 1217, 6882–6890.
    • (2010) J. Chromatogr. A , vol.1217 , pp. 6882-6890
    • Guillarme, D.1    Casetta, C.2    Bicchi, C.3    Veuthey, J.-L.4
  • 31
    • 34247589583 scopus 로고    scopus 로고
    • Rapid reversed phase ultra-performance liquid chromatography analysis of the major cocoa polyphenols and inter-relationships of their concentrations in chocolate
    • Cooper, K. A., Campos-Gimenez, E., Alvarez, D. J., Nagy, K., Donovan, J. L., Williamson, S. A. G. Rapid reversed phase ultra-performance liquid chromatography analysis of the major cocoa polyphenols and inter-relationships of their concentrations in chocolate. J. Agric. Food Chem. 2009, 55, 2841–2847.
    • (2009) J. Agric. Food Chem. , vol.55 , pp. 2841-2847
    • Cooper, K.A.1    Campos-Gimenez, E.2    Alvarez, D.J.3    Nagy, K.4    Donovan, J.L.5    Williamson, S.A.G.6
  • 32
    • 33645455557 scopus 로고    scopus 로고
    • High-performance liquid chromatography separation and purification of cacao (Theobroma cacao L.) procyanidins according to degree of polymerization using a diol stationary phase
    • Kelm, M. A., Johnson, J. C., Robbins, R. J., Hammerstone, J. F., Schmitz, H. H. High-performance liquid chromatography separation and purification of cacao (Theobroma cacao L.) procyanidins according to degree of polymerization using a diol stationary phase. J. Agric. Food Chem. 2006, 54, 1571–1576.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 1571-1576
    • Kelm, M.A.1    Johnson, J.C.2    Robbins, R.J.3    Hammerstone, J.F.4    Schmitz, H.H.5
  • 33
    • 65549101812 scopus 로고    scopus 로고
    • Method performance and multi-laboratory assessment of a normal phase high pressure liquid chromatography-fluorescence detection method for the quantitation of flavanols and procyanidins in cocoa and chocolate containing samples
    • Robbins, R. J., Leonczak, J., Johnson, J. C., Li, J., Kwik-Uribe, C., Prior, R. L., Gu, L. Method performance and multi-laboratory assessment of a normal phase high pressure liquid chromatography-fluorescence detection method for the quantitation of flavanols and procyanidins in cocoa and chocolate containing samples. J. Chromatogr. A 2009, 1216, 4831–4840.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 4831-4840
    • Robbins, R.J.1    Leonczak, J.2    Johnson, J.C.3    Li, J.4    Kwik-Uribe, C.5    Prior, R.L.6    Gu, L.7
  • 34
    • 84929248896 scopus 로고    scopus 로고
    • Rapid characterisation of grape seed extracts by a novel HPLC method on a diol stationary phase
    • Kuhnert, S., Lehmann, L., Winterhalter, P. Rapid characterisation of grape seed extracts by a novel HPLC method on a diol stationary phase. J. Funct. Foods 2015, 15, 225–232.
    • (2015) J. Funct. Foods , vol.15 , pp. 225-232
    • Kuhnert, S.1    Lehmann, L.2    Winterhalter, P.3
  • 35
    • 33746988541 scopus 로고    scopus 로고
    • Determination of theobromine, theophylline and caffeine in cocoa samples by a high-performance liquid chromatographic method with on-line sample cleanup in a switching-column system
    • del Rosario Brunetto, M., Gutiérrez, L., Delgado, Y. Determination of theobromine, theophylline and caffeine in cocoa samples by a high-performance liquid chromatographic method with on-line sample cleanup in a switching-column system. Food Chem. 2007, 100, 459–467.
    • (2007) Food Chem. , vol.100 , pp. 459-467
    • del Rosario Brunetto, M.1    Gutiérrez, L.2    Delgado, Y.3
  • 36
    • 0003569841 scopus 로고
    • Über die Bestimmung und den Gehalt von Theobromin und Theophyllin in Mate, Kola und Kakao
    • Franzke, C., Grunert, K. S., Griehl, H. Über die Bestimmung und den Gehalt von Theobromin und Theophyllin in Mate, Kola und Kakao. Eur. Food Res. Technol. 1969, 139, 85–87.
    • (1969) Eur. Food Res. Technol. , vol.139 , pp. 85-87
    • Franzke, C.1    Grunert, K.S.2    Griehl, H.3
  • 37
    • 70349934461 scopus 로고    scopus 로고
    • Survey of commercially available chocolate- and cocoa-containing products in the United States. 2. Comparison of flavan-3-ol content with nonfat cocoa solids, total polyphenols, and percent cacao
    • Miller, K. B., Hurst, W. J., Flannigan, N., Ou, B., Lee, C. Y., Smith, N., Stuart, D. A. Survey of commercially available chocolate- and cocoa-containing products in the United States. 2. Comparison of flavan-3-ol content with nonfat cocoa solids, total polyphenols, and percent cacao. J. Agric. Food Chem. 2009, 57, 9169–9180.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 9169-9180
    • Miller, K.B.1    Hurst, W.J.2    Flannigan, N.3    Ou, B.4    Lee, C.Y.5    Smith, N.6    Stuart, D.A.7
  • 40
    • 21244485837 scopus 로고    scopus 로고
    • Review: health effects of cocoa flavonoids
    • Lamuela-Raventós, R. M. Review: health effects of cocoa flavonoids. Food Sci. Technol. Int. 2005, 11, 159–176.
    • (2005) Food Sci. Technol. Int. , vol.11 , pp. 159-176
    • Lamuela-Raventós, R.M.1
  • 41
    • 84985092595 scopus 로고
    • Application of high-pressure liquid chromatography to the study of variables affecting theobromine and caffeine concentrations in cocoa beans
    • Timbie, D. J., Sechrist, L., Keeney, P. G. Application of high-pressure liquid chromatography to the study of variables affecting theobromine and caffeine concentrations in cocoa beans. J. Food Sci. 1978, 43, 560–565.
    • (1978) J. Food Sci , vol.43 , pp. 560-565
    • Timbie, D.J.1    Sechrist, L.2    Keeney, P.G.3
  • 42
    • 0033817478 scopus 로고    scopus 로고
    • Cocoa and chocolate: composition, bioavailability, and health implications
    • Borchers, A. T., Keen, C. L., Hannum, S. M., Gershwin, M. E. Cocoa and chocolate: composition, bioavailability, and health implications. J. Med. Food 2000, 3, 77–105.
    • (2000) J. Med. Food , vol.3 , pp. 77-105
    • Borchers, A.T.1    Keen, C.L.2    Hannum, S.M.3    Gershwin, M.E.4
  • 43
    • 0030376880 scopus 로고    scopus 로고
    • Determination of adenine, caffeine, theophylline and theobromine by HPLC with amperometric detection
    • Meyer, A., Ngiruwonsanga, T., Henze, G. N. Determination of adenine, caffeine, theophylline and theobromine by HPLC with amperometric detection. Fresen. J. Anal. Chem. 1996, 356, 284–287.
    • (1996) Fresen. J. Anal. Chem. , vol.356 , pp. 284-287
    • Meyer, A.1    Ngiruwonsanga, T.2    Henze, G.N.3
  • 44
    • 53249105530 scopus 로고    scopus 로고
    • Evaluation of xanthine derivatives in chocolate - nutritional and chemical aspects
    • Matissek, R. Evaluation of xanthine derivatives in chocolate - nutritional and chemical aspects. Z. Lebensm. Unters. For. A 1997, 205, 175–184.
    • (1997) Z. Lebensm. Unters. For. A , vol.205 , pp. 175-184
    • Matissek, R.1
  • 45
    • 84983419151 scopus 로고    scopus 로고
    • Edel- oder Konsumkakao? Eine Zuordnung anhand des T/C-Verhältnisses
    • Raters, M., Schnapka, J., Heeger, R., Matissek, R. Edel- oder Konsumkakao? Eine Zuordnung anhand des T/C-Verhältnisses. Lebensmittelchemie 2013, 67, 165.
    • (2013) Lebensmittelchemie , vol.67 , pp. 165
    • Raters, M.1    Schnapka, J.2    Heeger, R.3    Matissek, R.4
  • 47
    • 84982361750 scopus 로고
    • Leucoanthocyanins and related phenolic compounds of carob pods (Ceratonia Siliqua)
    • Joslyn, M. A., Nishira, H., Ito, S. Leucoanthocyanins and related phenolic compounds of carob pods (Ceratonia Siliqua). J. Sci. Food Agr. 1968, 19, 543–550.
    • (1968) J. Sci. Food Agr. , vol.19 , pp. 543-550
    • Joslyn, M.A.1    Nishira, H.2    Ito, S.3
  • 48
    • 0348008946 scopus 로고    scopus 로고
    • Optimized method for simultaneous determination of catechin, gallic acid, and methylxanthine compounds in chocolate using RP-HPLC
    • Tokusoglu, O., Unal, M. K. Optimized method for simultaneous determination of catechin, gallic acid, and methylxanthine compounds in chocolate using RP-HPLC. Eur. Food Res. Technol. 2002, 215, 340–346.
    • (2002) Eur. Food Res. Technol. , vol.215 , pp. 340-346
    • Tokusoglu, O.1    Unal, M.K.2
  • 49
    • 77049204584 scopus 로고
    • Cacao polyphenolic substances. 3. Separation and estimation on paper chromatograms
    • Forsyth, W. G. C. Cacao polyphenolic substances. 3. Separation and estimation on paper chromatograms. Biochem. J. 1955, 60, 108–111.
    • (1955) Biochem. J. , vol.60 , pp. 108-111
    • Forsyth, W.G.C.1
  • 50
    • 0000516501 scopus 로고
    • Polyphenols of mature plant, seedling and tissue cultures of Theobroma cacao
    • Jalal, M. A. F., Collin, H. A. Polyphenols of mature plant, seedling and tissue cultures of Theobroma cacao. Phytochemistry 1977, 16, 1377–1380.
    • (1977) Phytochemistry , vol.16 , pp. 1377-1380
    • Jalal, M.A.F.1    Collin, H.A.2
  • 51
    • 0027332378 scopus 로고
    • Normal-phase high-performance liquid chromatographic separation of procyanidins from cacao beans and grape seeds
    • Rigaud, J., Escribano-Bailon, M. T., Prieur, C., Souquet, J. M., Cheynier, V. Normal-phase high-performance liquid chromatographic separation of procyanidins from cacao beans and grape seeds. J. Chromatogr. A 1993, 654, 255–260.
    • (1993) J. Chromatogr. A , vol.654 , pp. 255-260
    • Rigaud, J.1    Escribano-Bailon, M.T.2    Prieur, C.3    Souquet, J.M.4    Cheynier, V.5
  • 53
    • 84865786030 scopus 로고    scopus 로고
    • Fast determination of N-phenylpropenoyl-L-amino acids (NPA) in cocoa samples from different origins by ultra-performance liquid chromatography and capillary electrophoresis
    • Lechtenberg, M., Henschel, K., Lieflaender-Wulf, U., Quandt, B., Hensel, A. Fast determination of N-phenylpropenoyl-L-amino acids (NPA) in cocoa samples from different origins by ultra-performance liquid chromatography and capillary electrophoresis. Food Chem. 2012, 135, 1676–1684.
    • (2012) Food Chem. , vol.135 , pp. 1676-1684
    • Lechtenberg, M.1    Henschel, K.2    Lieflaender-Wulf, U.3    Quandt, B.4    Hensel, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.