-
1
-
-
77955902024
-
The widespread regulation of microRNA biogenesis, function and decay
-
Krol, J., Loedige, I. & Filipowicz, W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11, 597-610 (2010).
-
(2010)
Nat Rev Genet
, vol.11
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
2
-
-
84904985459
-
Regulation of microRNA biogenesis
-
Ha, M. & Kim, V. N. Regulation of microRNA biogenesis. Nat Rev Mol Cell Biol 15, 509-524 (2014).
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 509-524
-
-
Ha, M.1
Kim, V.N.2
-
3
-
-
84938309401
-
Gene regulation breakers and blockers-mirnas at work
-
Izaurralde, E. Gene Regulation. Breakers and blockers-miRNAs at work. Science 349, 380-382 (2015).
-
(2015)
Science
, vol.349
, pp. 380-382
-
-
Izaurralde, E.1
-
4
-
-
18044402374
-
The human genome. Objection #2: Why sequence the junk?
-
Vogel, G. The human genome. Objection #2: why sequence the junk? Science 291, 1184 (2001).
-
(2001)
Science
, vol.291
, pp. 1184
-
-
Vogel, G.1
-
5
-
-
33846002394
-
A mouse for all reasons
-
Collins, F. S., Rossant, J. & Wurst, W. A mouse for all reasons. Cell 128, 9-13 (2007).
-
(2007)
Cell
, vol.128
, pp. 9-13
-
-
Collins, F.S.1
Rossant, J.2
Wurst, W.3
-
6
-
-
78651284860
-
The IKMC web portal: A central point of entry to data and resources from the International Knockout Mouse Consortium
-
Ringwald, M. et al. The IKMC web portal: A central point of entry to data and resources from the International Knockout Mouse Consortium. Nucleic Acids Res 39, D849-855 (2011).
-
(2011)
Nucleic Acids Res
, vol.39
, pp. D849-D855
-
-
Ringwald, M.1
-
7
-
-
79959210305
-
A conditional knockout resource for the genome-wide study of mouse gene function
-
Skarnes, W. C. et al. A conditional knockout resource for the genome-wide study of mouse gene function. Nature 474, 337-342 (2011).
-
(2011)
Nature
, vol.474
, pp. 337-342
-
-
Skarnes, W.C.1
-
8
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
-
9
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali, P. et al. RNA-guided human genome engineering via Cas9. Science 339, 823-826 (2013).
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
-
10
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang, H. et al. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153, 910-918 (2013).
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
-
11
-
-
84884289608
-
One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering
-
Yang, H. et al. One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell 154, 1370-1379 (2013).
-
(2013)
Cell
, vol.154
, pp. 1370-1379
-
-
Yang, H.1
-
12
-
-
84889589440
-
Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA
-
Mashiko, D. et al. Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA. Sci Rep 3, 3355 (2013).
-
(2013)
Sci Rep
, vol.3
, pp. 3355
-
-
Mashiko, D.1
-
13
-
-
84938945636
-
Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice
-
Aida, T. et al. Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice. Genome biology 16, 87 (2015).
-
(2015)
Genome Biology
, vol.16
, pp. 87
-
-
Aida, T.1
-
14
-
-
84903217296
-
Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system
-
Sakuma, T., Nishikawa, A., Kume, S., Chayama, K. & Yamamoto, T. Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system. Sci Rep 4, 5400 (2014).
-
(2014)
Sci Rep
, vol.4
, pp. 5400
-
-
Sakuma, T.1
Nishikawa, A.2
Kume, S.3
Chayama, K.4
Yamamoto, T.5
-
15
-
-
84891501836
-
Genome engineering of mammalian haploid embryonic stem cells using the Cas9/RNA system
-
Horii, T. et al. Genome engineering of mammalian haploid embryonic stem cells using the Cas9/RNA system. PeerJ 1, e230 (2013).
-
(2013)
PeerJ
, vol.1
, pp. e230
-
-
Horii, T.1
-
16
-
-
84905732049
-
Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes
-
Yen, S. T. et al. Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes. Dev Biol 393, 3-9 (2014).
-
(2014)
Dev Biol
, vol.393
, pp. 3-9
-
-
Yen, S.T.1
-
17
-
-
84936806646
-
Pervasive genotypic mosaicism in founder mice derived from genome editing through pronuclear injection
-
Oliver, D., Yuan, S., McSwiggin, H. & Yan, W. Pervasive Genotypic Mosaicism in Founder Mice Derived from Genome Editing through Pronuclear Injection. PLoS One 10, e0129457 (2015).
-
(2015)
PLoS One
, vol.10
, pp. e0129457
-
-
Oliver, D.1
Yuan, S.2
McSwiggin, H.3
Yan, W.4
-
18
-
-
84892659943
-
Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes
-
Mashiko, D. et al. Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes. Dev Growth Differ 56, 122-129 (2014).
-
(2014)
Dev Growth Differ
, vol.56
, pp. 122-129
-
-
Mashiko, D.1
-
19
-
-
84945208702
-
CRISPR/Cas9-mediated rapid generation of multiple mouse lines identified ccdc63 as essential for spermiogenesis
-
Young, S. A. et al. CRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines Identified Ccdc63 as Essential for Spermiogenesis. Int J Mol Sci 16, 24732-24750 (2015).
-
(2015)
Int J Mol Sci
, vol.16
, pp. 24732-24750
-
-
Young, S.A.1
-
20
-
-
0035449896
-
Alkalinization of acrosome measured by GFP as a pH indicator and its relation to sperm capacitation
-
Nakanishi, T., Ikawa, M., Yamada, S., Toshimori, K. & Okabe, M. Alkalinization of acrosome measured by GFP as a pH indicator and its relation to sperm capacitation. Dev Biol 237, 222-231 (2001).
-
(2001)
Dev Biol
, vol.237
, pp. 222-231
-
-
Nakanishi, T.1
Ikawa, M.2
Yamada, S.3
Toshimori, K.4
Okabe, M.5
-
21
-
-
84871368189
-
Production of mouse pups from germline transmission-failed knockout chimeras
-
Fujihara, Y., Kaseda, K., Inoue, N., Ikawa, M. & Okabe, M. Production of mouse pups from germline transmission-failed knockout chimeras. Transgenic Res 22, 195-200 (2013).
-
(2013)
Transgenic Res
, vol.22
, pp. 195-200
-
-
Fujihara, Y.1
Kaseda, K.2
Inoue, N.3
Ikawa, M.4
Okabe, M.5
-
22
-
-
84880668424
-
Germline deletion of Cetn1 causes infertility in male mice
-
Avasthi, P. et al. Germline deletion of Cetn1 causes infertility in male mice. J Cell Sci 126, 3204-3213 (2013).
-
(2013)
J Cell Sci
, vol.126
, pp. 3204-3213
-
-
Avasthi, P.1
-
23
-
-
78649568749
-
DNAJB13 is a radial spoke protein of mouse 9 + 2 axoneme
-
Guan, J., Ekwurtzel, E., Kvist, U., Hultenby, K. & Yuan, L. DNAJB13 is a radial spoke protein of mouse 9 + 2 axoneme. Reprod Domest Anim 45, 992-996 (2010).
-
(2010)
Reprod Domest Anim
, vol.45
, pp. 992-996
-
-
Guan, J.1
Ekwurtzel, E.2
Kvist, U.3
Hultenby, K.4
Yuan, L.5
-
24
-
-
84929134273
-
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells
-
Liao, J. et al. Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Nat Genet 47, 469-478 (2015).
-
(2015)
Nat Genet
, vol.47
, pp. 469-478
-
-
Liao, J.1
-
25
-
-
18844396119
-
Embryonic stem cell differentiation: Emergence of a new era in biology and medicine
-
Keller, G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev 19, 1129-1155 (2005).
-
(2005)
Genes Dev
, vol.19
, pp. 1129-1155
-
-
Keller, G.1
-
26
-
-
39349106325
-
Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
-
Murry, C. E. & Keller, G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 132, 661-680 (2008).
-
(2008)
Cell
, vol.132
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
27
-
-
47749151047
-
A heat-shock protein 40, DNAJB13, is an axoneme-Associated component in mouse spermatozoa
-
Guan, J. & Yuan, L. A heat-shock protein 40, DNAJB13, is an axoneme-Associated component in mouse spermatozoa. Mol Reprod Dev 75, 1379-1386 (2008).
-
(2008)
Mol Reprod Dev
, vol.75
, pp. 1379-1386
-
-
Guan, J.1
Yuan, L.2
-
28
-
-
38549178973
-
Primary ciliary dyskinesia in mice lacking the novel ciliary protein Pcdp1
-
Lee, L. et al. Primary ciliary dyskinesia in mice lacking the novel ciliary protein Pcdp1. Mol Cell Biol 28, 949-957 (2008).
-
(2008)
Mol Cell Biol
, vol.28
, pp. 949-957
-
-
Lee, L.1
-
29
-
-
84942155370
-
CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice
-
McKenzie, C. W. et al. CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice. Mol Biol Cell 26, 3140-3149 (2015).
-
(2015)
Mol Biol Cell
, vol.26
, pp. 3140-3149
-
-
McKenzie, C.W.1
-
30
-
-
0029796633
-
Long-Term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
-
Osawa, M., Hanada, K., Hamada, H. & Nakauchi, H. Long-Term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273, 242-245 (1996).
-
(1996)
Science
, vol.273
, pp. 242-245
-
-
Osawa, M.1
Hanada, K.2
Hamada, H.3
Nakauchi, H.4
-
31
-
-
0037623736
-
Long-Term proliferation in culture and germline transmission of mouse male germline stem cells
-
Kanatsu-Shinohara, M. et al. Long-Term proliferation in culture and germline transmission of mouse male germline stem cells. Biol Reprod 69, 612-616 (2003).
-
(2003)
Biol Reprod
, vol.69
, pp. 612-616
-
-
Kanatsu-Shinohara, M.1
-
32
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
Abecasis, G. R. et al. A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073 (2010).
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
Abecasis, G.R.1
-
33
-
-
84885645853
-
Transcriptome and genome sequencing uncovers functional variation in humans
-
Lappalainen, T. et al. Transcriptome and genome sequencing uncovers functional variation in humans. Nature 501, 506-511 (2013).
-
(2013)
Nature
, vol.501
, pp. 506-511
-
-
Lappalainen, T.1
-
34
-
-
84923384373
-
Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice
-
Kraft, K. et al. Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice. Cell Rep, doi: 10.1016/j.celrep.2015.01.016 (2015).
-
(2015)
Cell Rep
-
-
Kraft, K.1
-
35
-
-
84959375643
-
Chromosome engineering in zygotes with CRISPR/Cas9
-
Boroviak, K., Doe, B., Banerjee, R., Yang, F. & Bradley, A. Chromosome engineering in zygotes with CRISPR/Cas9. Genesis, doi: 10.1002/dvg.22915 (2016).
-
(2016)
Genesis
-
-
Boroviak, K.1
Doe, B.2
Banerjee, R.3
Yang, F.4
Bradley, A.5
-
36
-
-
84925405886
-
CRISPR/Cas9-based genome editing in mice by single plasmid injection
-
Fujihara, Y. & Ikawa, M. CRISPR/Cas9-based genome editing in mice by single plasmid injection. Methods Enzymol 546, 319-336 (2014).
-
(2014)
Methods Enzymol
, vol.546
, pp. 319-336
-
-
Fujihara, Y.1
Ikawa, M.2
-
37
-
-
0012315579
-
-
Cold Spring Harbor Laboratory Press
-
Nagy, A., Gertsenstein, M., Vintersten, K. & Behringer, R. Manipulating the Mouse Embryo: A Laboratory Manual 3rd edition, 800 (Cold Spring Harbor Laboratory Press, 2003).
-
(2003)
Manipulating the Mouse Embryo: A Laboratory Manual 3rd Edition
, vol.800
-
-
Nagy, A.1
Gertsenstein, M.2
Vintersten, K.3
Behringer, R.4
|