The unfolded protein response: Mechanisms and therapy of neurodegeneration

Brain

Volumn 139, Issue 8, 2016, Pages 2113-2121

  Smith, Heather L ^a   Mallucci, Giovanna R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

mouse models of neurodegeneration; neurodegeneration; neuroprotection; treatment of dementia; unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; GSK 2606414; INITIATION FACTOR 2; INITIATION FACTOR 2ALPHA; INOSITOL REQUIRING ENZYME 1; ISRIB; MEMBRANE PROTEIN; NEUROPROTECTIVE AGENT; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN; PROTEIN KINASE RNA LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN KINASE RNA LIKE ENDOPLASMIC RETICULUM KINASE INHIBITOR; SALUBRINAL; SEPHRIN 1; UNCLASSIFIED DRUG; PROTEIN KINASE R;

ALZHEIMER DISEASE; ARTICLE; BRAIN ATROPHY; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITION; FRONTOTEMPORAL DEMENTIA; HUMAN; LEARNING; MEMORY; NERVE CELL; NERVE CELL PLASTICITY; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROGRESSIVE SUPRANUCLEAR PALSY; PROTEIN PROCESSING; PROTEIN QUALITY; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSLATION REGULATION; UNFOLDED PROTEIN RESPONSE; ANIMAL; DEMENTIA; DRUG EFFECTS; METABOLISM; MOUSE; NEURODEGENERATIVE DISEASES;

ANIMALS; DEMENTIA; EIF-2 KINASE; HUMANS; MICE; NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; UNFOLDED PROTEIN RESPONSE;

EID: 84982915210     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/aww101     Document Type: Article

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