-
1
-
-
33750445482
-
Mitochondrial fusion and fission in mammals
-
Chan DC. Mitochondrial fusion and fission in mammals. Annu Rev Cell Dev Biol. 2006;22:79–99.
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 79-99
-
-
Chan, D.C.1
-
2
-
-
84865187064
-
Inhibition of Drp1 provides neuroprotection in vitro and in vivo
-
Grohm J, Kim SW, Mamrak U, et al. Inhibition of Drp1 provides neuroprotection in vitro and in vivo. Cell Death Differ. 2012;19:1446–1458.
-
(2012)
Cell Death Differ
, vol.19
, pp. 1446-1458
-
-
Grohm, J.1
Kim, S.W.2
Mamrak, U.3
-
3
-
-
84868127674
-
Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit
-
Pham AH, Meng S, Chu QN, et al. Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit. Hum Mol Genet. 2012;21:4817–4826.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4817-4826
-
-
Pham, A.H.1
Meng, S.2
Chu, Q.N.3
-
4
-
-
67649756320
-
Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease
-
Bueler H. Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease. Exp Neurol. 2009;218:235–246.
-
(2009)
Exp Neurol
, vol.218
, pp. 235-246
-
-
Bueler, H.1
-
5
-
-
79957974579
-
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein
-
Nakamura K, Nemani VM, Azarbal F, et al. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. J Biol Chem. 2011;286:20710–20726.
-
(2011)
J Biol Chem
, vol.286
, pp. 20710-20726
-
-
Nakamura, K.1
Nemani, V.M.2
Azarbal, F.3
-
6
-
-
79953231682
-
Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease
-
Wang H, Song P, Du L, et al. Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease. J Biol Chem. 2011;286:11649–11658.
-
(2011)
J Biol Chem
, vol.286
, pp. 11649-11658
-
-
Wang, H.1
Song, P.2
Du, L.3
-
7
-
-
84860539187
-
Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction
-
Wang X, Petrie TG, Liu Y, et al. Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction. J Neurochem. 2012;121:830–839.
-
(2012)
J Neurochem
, vol.121
, pp. 830-839
-
-
Wang, X.1
Petrie, T.G.2
Liu, Y.3
-
8
-
-
67649399288
-
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
-
Dagda RK, Cherra SJ III, Kulich SM, et al. Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J Biol Chem. 2009;284:13843–13855.
-
(2009)
J Biol Chem
, vol.284
, pp. 13843-13855
-
-
Dagda, R.K.1
Cherra, S.J.2
Kulich, S.M.3
-
9
-
-
80052794422
-
DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease
-
Wang X, Su B, Liu W, et al. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell. 2011;10:807–823.
-
(2011)
Aging Cell
, vol.10
, pp. 807-823
-
-
Wang, X.1
Su, B.2
Liu, W.3
-
10
-
-
43149115834
-
6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells
-
Gomez-Lazaro M, Bonekamp NA, Galindo MF, et al. 6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells. Free Radic Biol Med. 2008;44:1960–1969.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 1960-1969
-
-
Gomez-Lazaro, M.1
Bonekamp, N.A.2
Galindo, M.F.3
-
11
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature. 2006;443:787–795.
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
12
-
-
0036255661
-
+-induced neurodegeneration and glutathione impairment in the nigrostriatal dopaminergic pathway
-
+-induced neurodegeneration and glutathione impairment in the nigrostriatal dopaminergic pathway. J Pineal Res. 2002;32:262–269.
-
(2002)
J Pineal Res
, vol.32
, pp. 262-269
-
-
Chen, S.T.1
Chuang, J.I.2
Hong, M.H.3
-
13
-
-
0028067656
-
Glutathione-related enzymes in brain in Parkinson's disease
-
Sian J, Dexter DT, Lees AJ, et al. Glutathione-related enzymes in brain in Parkinson's disease. Ann Neurol. 1994;36:356–361.
-
(1994)
Ann Neurol
, vol.36
, pp. 356-361
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
-
14
-
-
84884901192
-
Glutathione metabolism and Parkinson's disease
-
Smeyne M, Smeyne RJ. Glutathione metabolism and Parkinson's disease. Free Radic Biol Med. 2013;62:13–25.
-
(2013)
Free Radic Biol Med
, vol.62
, pp. 13-25
-
-
Smeyne, M.1
Smeyne, R.J.2
-
15
-
-
33749047253
-
Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease
-
Chinta SJ, Andersen JK. Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease. Free Radic Biol Med. 2006;41:1442–1448.
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 1442-1448
-
-
Chinta, S.J.1
Andersen, J.K.2
-
16
-
-
84867032955
-
The intracellular redox state is a core determinant of mitochondrial fusion
-
Shutt T, Geoffrion M, Milne R, et al. The intracellular redox state is a core determinant of mitochondrial fusion. EMBO Rep. 2012;13:909–915.
-
(2012)
EMBO Rep
, vol.13
, pp. 909-915
-
-
Shutt, T.1
Geoffrion, M.2
Milne, R.3
-
17
-
-
64249133725
-
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury
-
Cho DH, Nakamura T, Fang J, et al. S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. Science. 2009;324:102–105.
-
(2009)
Science
, vol.324
, pp. 102-105
-
-
Cho, D.H.1
Nakamura, T.2
Fang, J.3
-
18
-
-
33748028841
-
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons
-
Barsoum MJ, Yuan H, Gerencser AA, et al. Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. EMBO J. 2006;25:3900–3911.
-
(2006)
EMBO J
, vol.25
, pp. 3900-3911
-
-
Barsoum, M.J.1
Yuan, H.2
Gerencser, A.A.3
-
19
-
-
34548274600
-
Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death
-
Jahani-Asl A, Cheung EC, Neuspiel M, et al. Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death. J Biol Chem. 2007;282:23788–23798.
-
(2007)
J Biol Chem
, vol.282
, pp. 23788-23798
-
-
Jahani-Asl, A.1
Cheung, E.C.2
Neuspiel, M.3
-
20
-
-
84925835510
-
Melatonin: a well-documented antioxidant with conditional pro-oxidant actions
-
Zhang HM, Zhang Y. Melatonin: a well-documented antioxidant with conditional pro-oxidant actions. J Pineal Res. 2014;57:131–146.
-
(2014)
J Pineal Res
, vol.57
, pp. 131-146
-
-
Zhang, H.M.1
Zhang, Y.2
-
21
-
-
84946481377
-
Melatonin: an ancient molecule that makes oxygen metabolically tolerable
-
Manchester LC, Coto-Montes A, Boga JA, et al. Melatonin: an ancient molecule that makes oxygen metabolically tolerable. J Pineal Res. 2015;59:403–419.
-
(2015)
J Pineal Res
, vol.59
, pp. 403-419
-
-
Manchester, L.C.1
Coto-Montes, A.2
Boga, J.A.3
-
22
-
-
84938417554
-
Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling
-
Zhao L, An R, Yang Y, et al. Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling. J Pineal Res. 2015;59:230–239.
-
(2015)
J Pineal Res
, vol.59
, pp. 230-239
-
-
Zhao, L.1
An, R.2
Yang, Y.3
-
23
-
-
1342280378
-
Effect of melatonin on temporal changes of reactive oxygen species and glutathione after MPP(+) treatment in human astrocytoma U373MG cells
-
Chuang JI, Chen TH. Effect of melatonin on temporal changes of reactive oxygen species and glutathione after MPP(+) treatment in human astrocytoma U373MG cells. J Pineal Res. 2004;36:117–125.
-
(2004)
J Pineal Res
, vol.36
, pp. 117-125
-
-
Chuang, J.I.1
Chen, T.H.2
-
24
-
-
79954420629
-
Melatonin preserves the transient mitochondrial permeability transition for protection during mitochondrial Ca(2+) stress in astrocyte
-
Jou MJ. Melatonin preserves the transient mitochondrial permeability transition for protection during mitochondrial Ca(2+) stress in astrocyte. J Pineal Res. 2011;50:427–435.
-
(2011)
J Pineal Res
, vol.50
, pp. 427-435
-
-
Jou, M.J.1
-
25
-
-
68249090104
-
Long-term melatonin administration protects brain mitochondria from aging
-
Carretero M, Escames G, Lopez LC, et al. Long-term melatonin administration protects brain mitochondria from aging. J Pineal Res. 2009;47:192–200.
-
(2009)
J Pineal Res
, vol.47
, pp. 192-200
-
-
Carretero, M.1
Escames, G.2
Lopez, L.C.3
-
26
-
-
84883744391
-
Melatonin attenuates methamphetamine-induced disturbances in mitochondrial dynamics and degeneration in neuroblastoma SH-SY5Y cells
-
Parameyong A, Charngkaew K, Govitrapong P, et al. Melatonin attenuates methamphetamine-induced disturbances in mitochondrial dynamics and degeneration in neuroblastoma SH-SY5Y cells. J Pineal Res. 2013;55:313–323.
-
(2013)
J Pineal Res
, vol.55
, pp. 313-323
-
-
Parameyong, A.1
Charngkaew, K.2
Govitrapong, P.3
-
27
-
-
77955516215
-
Fibroblast growth factor 9 upregulates heme oxygenase-1 and gamma-glutamylcysteine synthetase expression to protect neurons from 1-methyl-4-phenylpyridinium toxicity
-
Huang JY, Chuang JI. Fibroblast growth factor 9 upregulates heme oxygenase-1 and gamma-glutamylcysteine synthetase expression to protect neurons from 1-methyl-4-phenylpyridinium toxicity. Free Radic Biol Med. 2010;49:1099–1108.
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 1099-1108
-
-
Huang, J.Y.1
Chuang, J.I.2
-
28
-
-
65549161425
-
+-induced death of dopaminergic neurons and is involved in melatonin neuroprotection in vivo and in vitro
-
+-induced death of dopaminergic neurons and is involved in melatonin neuroprotection in vivo and in vitro. J Neurochem. 2009;109:1400–1412.
-
(2009)
J Neurochem
, vol.109
, pp. 1400-1412
-
-
Huang, J.Y.1
Hong, Y.T.2
-
29
-
-
0022272493
-
Determination of glutathione and glutathione disulfide in biological samples
-
Anderson ME. Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 1985;113:548–555.
-
(1985)
Methods Enzymol
, vol.113
, pp. 548-555
-
-
Anderson, M.E.1
-
30
-
-
17144429793
-
Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission
-
de Vos KJ, Allan VJ, Grierson AJ, et al. Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission. Curr Biol. 2005;15:678–683.
-
(2005)
Curr Biol
, vol.15
, pp. 678-683
-
-
de Vos, K.J.1
Allan, V.J.2
Grierson, A.J.3
-
32
-
-
33947356299
-
Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis
-
Meuer K, Suppanz IE, Lingor P, et al. Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis. Cell Death Differ. 2007;14:651–661.
-
(2007)
Cell Death Differ
, vol.14
, pp. 651-661
-
-
Meuer, K.1
Suppanz, I.E.2
Lingor, P.3
-
33
-
-
84876312885
-
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity
-
Qi X, Qvit N, Su YC, et al. A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. J Cell Sci. 2013;126:789–802.
-
(2013)
J Cell Sci
, vol.126
, pp. 789-802
-
-
Qi, X.1
Qvit, N.2
Su, Y.C.3
-
34
-
-
84908079648
-
Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons
-
Berthet A, Margolis EB, Zhang J, et al. Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons. J Neurosci. 2014;34:14304–14317.
-
(2014)
J Neurosci
, vol.34
, pp. 14304-14317
-
-
Berthet, A.1
Margolis, E.B.2
Zhang, J.3
-
35
-
-
84868110583
-
Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons
-
Lee S, Sterky FH, Mourier A, et al. Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Hum Mol Genet. 2012;21:4827–4835.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4827-4835
-
-
Lee, S.1
Sterky, F.H.2
Mourier, A.3
-
36
-
-
65849443539
-
Mitochondrial fragmentation is involved in methamphetamine-induced cell death in rat hippocampal neural progenitor cells
-
Tian C, Murrin LC, Zheng JC. Mitochondrial fragmentation is involved in methamphetamine-induced cell death in rat hippocampal neural progenitor cells. PLoS One. 2009;4:e5546.
-
(2009)
PLoS One
, vol.4
-
-
Tian, C.1
Murrin, L.C.2
Zheng, J.C.3
-
37
-
-
84866611374
-
Characterization of mitophagy in the 6-hydoxydopamine Parkinson's disease model
-
Solesio ME, Saez-Atienzar S, Jordan J, et al. Characterization of mitophagy in the 6-hydoxydopamine Parkinson's disease model. Toxicol Sci. 2012;129:411–420.
-
(2012)
Toxicol Sci
, vol.129
, pp. 411-420
-
-
Solesio, M.E.1
Saez-Atienzar, S.2
Jordan, J.3
-
38
-
-
46749156297
-
Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species
-
Yu T, Sheu SS, Robotham JL, et al. Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species. Cardiovasc Res. 2008;79:341–351.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 341-351
-
-
Yu, T.1
Sheu, S.S.2
Robotham, J.L.3
-
39
-
-
84885596203
-
Decline in cytochrome c oxidase activity in rat-brain mitochondria with aging. Role of peroxidized cardiolipin and beneficial effect of melatonin
-
Petrosillo G, de Benedictis V, Ruggiero FM, et al. Decline in cytochrome c oxidase activity in rat-brain mitochondria with aging. Role of peroxidized cardiolipin and beneficial effect of melatonin. J Bioenerg Biomembr. 2013;45:431–440.
-
(2013)
J Bioenerg Biomembr
, vol.45
, pp. 431-440
-
-
Petrosillo, G.1
de Benedictis, V.2
Ruggiero, F.M.3
-
40
-
-
0006295841
-
Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo
-
Martin M, Macias M, Escames G, et al. Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo. J Pineal Res. 2000;28:242–248.
-
(2000)
J Pineal Res
, vol.28
, pp. 242-248
-
-
Martin, M.1
Macias, M.2
Escames, G.3
|