-
1
-
-
0345686712
-
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
-
Hirsch LR, Stafford RJ, Bankson JA, et al. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci U S A. 2003;100(23):13549–13554.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.23
, pp. 13549-13554
-
-
Hirsch, L.R.1
Stafford, R.J.2
Bankson, J.A.3
-
2
-
-
84878342570
-
Stable conjugates of peptides with gold nanorods for biomedical applications with reduced effects on cell viability
-
Adura C, Guerrero S, Salas E, et al. Stable conjugates of peptides with gold nanorods for biomedical applications with reduced effects on cell viability. ACS Appl Mater Interfaces. 2013;5(10):4076–4085.
-
(2013)
ACS Appl Mater Interfaces
, vol.5
, Issue.10
, pp. 4076-4085
-
-
Adura, C.1
Guerrero, S.2
Salas, E.3
-
3
-
-
34250327940
-
Peptides and metallic nanoparticles for biomedical applications
-
Kogan MJ, Olmedo I, Hosta L, Guerrero AR, Cruz LJ, Albericio F. Peptides and metallic nanoparticles for biomedical applications. Nanomedicine. 2007;2(3):287–306.
-
(2007)
Nanomedicine
, vol.2
, Issue.3
, pp. 287-306
-
-
Kogan, M.J.1
Olmedo, I.2
Hosta, L.3
Guerrero, A.R.4
Cruz, L.J.5
Albericio, F.6
-
4
-
-
25844475286
-
Methotrexate-modified superparamagnetic nanoparticles and their intracellular uptake into human cancer cells
-
Kohler N, Sun C, Wang J, Zhang M. Methotrexate-modified superparamagnetic nanoparticles and their intracellular uptake into human cancer cells. Langmuir. 2005;21(19):8858–8864.
-
(2005)
Langmuir
, vol.21
, Issue.19
, pp. 8858-8864
-
-
Kohler, N.1
Sun, C.2
Wang, J.3
Zhang, M.4
-
5
-
-
31544459915
-
Nanoparticle-mediated local and remote manipulation of protein aggregation
-
Kogan MJ, Bastus NG, Amigo R, et al. Nanoparticle-mediated local and remote manipulation of protein aggregation. Nano Lett. 2006;6(1):110–115.
-
(2006)
Nano Lett
, vol.6
, Issue.1
, pp. 110-115
-
-
Kogan, M.J.1
Bastus, N.G.2
Amigo, R.3
-
6
-
-
54949120918
-
Gold nanoparticles and microwave irradiation inhibit beta-amyloid amyloidogenesis
-
Araya E, Olmedo I, Bastus N, et al. Gold nanoparticles and microwave irradiation inhibit beta-amyloid amyloidogenesis. Nanoscale Res Lett. 2008;3(11):435–443.
-
(2008)
Nanoscale Res Lett.
, vol.3
, Issue.11
, pp. 435-443
-
-
Araya, E.1
Olmedo, I.2
Bastus, N.3
-
7
-
-
84869498477
-
Challenges in drug delivery to the brain: Nature is against us
-
Krol S. Challenges in drug delivery to the brain: nature is against us. J Control Release. 2012;164(2):145–155.
-
(2012)
J Control Release
, vol.164
, Issue.2
, pp. 145-155
-
-
Krol, S.1
-
8
-
-
78649817896
-
A novel class of potential prion drugs: Preliminary in vitro and in vivo data for multilayer coated gold nanoparticles
-
Ai Tran HN, Sousa F, Moda F, et al. A novel class of potential prion drugs: preliminary in vitro and in vivo data for multilayer coated gold nanoparticles. Nanoscale. 2010;2(12):2724–2732.
-
(2010)
Nanoscale
, vol.2
, Issue.12
, pp. 2724-2732
-
-
Ai Tran, H.N.1
Sousa, F.2
Moda, F.3
-
9
-
-
78649851994
-
Functionalized gold nanoparticles: A detailed in vivo multimodal microscopic brain distribution study
-
Sousa F, Mandal S, Garrovo C, et al. Functionalized gold nanoparticles: a detailed in vivo multimodal microscopic brain distribution study. Nanoscale. 2010;2(12):2826–2834.
-
(2010)
Nanoscale
, vol.2
, Issue.12
, pp. 2826-2834
-
-
Sousa, F.1
Mandal, S.2
Garrovo, C.3
-
10
-
-
42049091686
-
Photothermal ablation of amyloid aggregates by gold nanoparticles
-
Triulzi RC, Dai Q, Zou J, et al. Photothermal ablation of amyloid aggregates by gold nanoparticles. Colloids Surf B Biointerfaces. 2008;63(2):200–208.
-
(2008)
Colloids Surf B Biointerfaces
, vol.63
, Issue.2
, pp. 200-208
-
-
Triulzi, R.C.1
Dai, Q.2
Zou, J.3
-
11
-
-
80051819208
-
The use of a gold nanoparticle-based adjuvant to improve the therapeutic efficacy of hNgR-Fc protein immunization in spinal cord-injured rats
-
Wang YT, Lu XM, Zhu F, et al. The use of a gold nanoparticle-based adjuvant to improve the therapeutic efficacy of hNgR-Fc protein immunization in spinal cord-injured rats. Biomaterials. 2011;32(31):7988–7998.
-
(2011)
Biomaterials
, vol.32
, Issue.31
, pp. 7988-7998
-
-
Wang, Y.T.1
Lu, X.M.2
Zhu, F.3
-
12
-
-
84865458775
-
X-ray microscopy and tomography detect the accumulation of bare and PEG-coated gold nanoparticles in normal and tumor mouse tissues
-
Chien CC, Cheng CC, Chen HH, et al. X-ray microscopy and tomography detect the accumulation of bare and PEG-coated gold nanoparticles in normal and tumor mouse tissues. Anal Bioanal Chem. 2012;404(5):1287–1296.
-
(2012)
Anal Bioanal Chem
, vol.404
, Issue.5
, pp. 1287-1296
-
-
Chien, C.C.1
Cheng, C.C.2
Chen, H.H.3
-
13
-
-
38049117492
-
Photoacoustic tomography of a rat cerebral cortex in vivo with au nanocages as an optical contrast agent
-
Yang X, Skrabalak SE, Li ZY, Xia Y, Wang LV. Photoacoustic tomography of a rat cerebral cortex in vivo with au nanocages as an optical contrast agent. Nano Lett. 2007;7(12):3798–3802.
-
(2007)
Nano Lett
, vol.7
, Issue.12
, pp. 3798-3802
-
-
Yang, X.1
Skrabalak, S.E.2
Li, Z.Y.3
Xia, Y.4
Wang, L.V.5
-
14
-
-
74449093082
-
Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheres
-
Lu W, Huang Q, Ku G, et al. Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheres. Biomaterials. 2010;31(9):2617–2626.
-
(2010)
Biomaterials
, vol.31
, Issue.9
, pp. 2617-2626
-
-
Lu, W.1
Huang, Q.2
Ku, G.3
-
15
-
-
84868667194
-
Gold-nanorod contrast-enhanced photoacoustic micro-imaging of focused-ultrasound induced blood-brain-barrier opening in a rat model
-
Wang PH, Liu HL, Hsu PH, et al. Gold-nanorod contrast-enhanced photoacoustic micro-imaging of focused-ultrasound induced blood-brain-barrier opening in a rat model. J Biomed Opt. 2012;17(6):061222.
-
(2012)
J Biomed Opt
, vol.17
, Issue.6
-
-
Wang, P.H.1
Liu, H.L.2
Hsu, P.H.3
-
16
-
-
84871404093
-
The big picture on nanomedicine: The state of investigational and approved nanomedicine products
-
Etheridge ML, Campbell SA, Erdman AG, Haynes CL, Wolf SM, McCullough J. The big picture on nanomedicine: the state of investigational and approved nanomedicine products. Nanomedicine. 2013;9(1):1–14.
-
(2013)
Nanomedicine
, vol.9
, Issue.1
, pp. 1-14
-
-
Etheridge, M.L.1
Campbell, S.A.2
Erdman, A.G.3
Haynes, C.L.4
Wolf, S.M.5
McCullough, J.6
-
17
-
-
78650348824
-
Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine
-
Libutti SK, Paciotti GF, Byrnes AA, et al. Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine. Clin Cancer Res. 2010;16(24):6139–6149.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.24
, pp. 6139-6149
-
-
Libutti, S.K.1
Paciotti, G.F.2
Byrnes, A.A.3
-
18
-
-
0014060520
-
Fine structure observations of the uptake of intravenously injected peroxidase by the rat choroid plexus
-
Becker NH, Novikoff AB, Zimmerman HM. Fine structure observations of the uptake of intravenously injected peroxidase by the rat choroid plexus. J Histochem Cytochem. 1967;15(3):160–165.
-
(1967)
J Histochem Cytochem
, vol.15
, Issue.3
, pp. 160-165
-
-
Becker, N.H.1
Novikoff, A.B.2
Zimmerman, H.M.3
-
19
-
-
0016718746
-
Junctions in the meninges and marginal glia
-
Nabeshima S, Reese TS, Landis DM, Brightman MW. Junctions in the meninges and marginal glia. J Comp Neurol. 1975;164(2):127–169.
-
(1975)
J Comp Neurol
, vol.164
, Issue.2
, pp. 127-169
-
-
Nabeshima, S.1
Reese, T.S.2
Landis, D.M.3
Brightman, M.W.4
-
20
-
-
0014109002
-
Fine structural localization of a blood-brain barrier to exogenous peroxidase
-
Reese TS, Karnovsky MJ. Fine structural localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol. 1967;34(1):207–217.
-
(1967)
J Cell Biol
, vol.34
, Issue.1
, pp. 207-217
-
-
Reese, T.S.1
Karnovsky, M.J.2
-
21
-
-
0002608801
-
Comparative physiology of the blood-brain barrier
-
Bradbury MB, editor, Berlin: Springer
-
Abbott NJ. Comparative physiology of the blood-brain barrier. In: Bradbury MB, editor. Physiology and Pharmacology of the Blood-Brain Barrier. Vol. 103. Berlin: Springer; 1992:371–396.
-
(1992)
Physiology and Pharmacology of the Blood-Brain Barrier
, vol.103
, pp. 371-396
-
-
Abbott, N.J.1
-
22
-
-
70449529433
-
Structure and function of the blood-brain barrier
-
Abbott NJ, Patabendige AA, Dolman DE, Yusof SR, Begley DJ. Structure and function of the blood-brain barrier. Neurobiol Dis. 2010;37(1):13–25.
-
(2010)
Neurobiol Dis
, vol.37
, Issue.1
, pp. 13-25
-
-
Abbott, N.J.1
Patabendige, A.A.2
Dolman, D.E.3
Yusof, S.R.4
Begley, D.J.5
-
23
-
-
80053542940
-
Getting to know the cast – cellular interactions and signaling at the neurovascular unit
-
Mae M, Armulik A, Betsholtz C. Getting to know the cast – cellular interactions and signaling at the neurovascular unit. Curr Pharm Des. 2011;17(26):2750–2754.
-
(2011)
Curr Pharm Des
, vol.17
, Issue.26
, pp. 2750-2754
-
-
Mae, M.1
Armulik, A.2
Betsholtz, C.3
-
24
-
-
79957755796
-
Morphology and properties of brain endothelial cells
-
Nag S. Morphology and properties of brain endothelial cells. Methods Mol Biol. 2011;686:3–47.
-
(2011)
Methods Mol Biol
, vol.686
, pp. 3-47
-
-
Nag, S.1
-
25
-
-
77954394706
-
The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction
-
Mathiisen TM, Lehre KP, Danbolt NC, Ottersen OP. The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction. Glia. 2010;58(9):1094–1103.
-
(2010)
Glia
, vol.58
, Issue.9
, pp. 1094-1103
-
-
Mathiisen, T.M.1
Lehre, K.P.2
Danbolt, N.C.3
Ottersen, O.P.4
-
26
-
-
84885754029
-
Physiological roles of aquaporin-4 in brain
-
Nagelhus EA, Ottersen OP. Physiological roles of aquaporin-4 in brain. Physiol Rev. 2013;93(4):1543–1562.
-
(2013)
Physiol Rev
, vol.93
, Issue.4
, pp. 1543-1562
-
-
Nagelhus, E.A.1
Ottersen, O.P.2
-
27
-
-
84865123660
-
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta
-
Iliff JJ, Wang M, Liao Y, et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta. Sci Transl Med. 2012;4(147):147ra111.
-
(2012)
Sci Transl Med
, vol.4
, Issue.147
-
-
Iliff, J.J.1
Wang, M.2
Liao, Y.3
-
28
-
-
84879651014
-
Neuroscience. Garbage truck of the brain
-
Nedergaard M. Neuroscience. Garbage truck of the brain. Science. 2013;340(6140):1529–1530.
-
(2013)
Science
, vol.340
, Issue.6140
, pp. 1529-1530
-
-
Nedergaard, M.1
-
30
-
-
84887399490
-
Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain
-
Iliff JJ, Wang M, Zeppenfeld DM, et al. Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain. J Neurosci. 2013;33(46):18190–18199.
-
(2013)
J Neurosci
, vol.33
, Issue.46
, pp. 18190-18199
-
-
Iliff, J.J.1
Wang, M.2
Zeppenfeld, D.M.3
-
31
-
-
84885775321
-
Sleep drives metabolite clearance from the adult brain
-
Xie L, Kang H, Xu Q, et al. Sleep drives metabolite clearance from the adult brain. Science. 2013;342(6156):373–377.
-
(2013)
Science
, vol.342
, Issue.6156
, pp. 373-377
-
-
Xie, L.1
Kang, H.2
Xu, Q.3
-
32
-
-
33745694051
-
Mechanistic aspects of CPP-mediated intracellular drug delivery: Relevance of CPP self-assembly
-
Pujals S, Fernandez-Carneado J, Lopez-Iglesias C, Kogan MJ, Giralt E. Mechanistic aspects of CPP-mediated intracellular drug delivery: relevance of CPP self-assembly. Biochim Biophys Acta. 2006;1758(3):264–279.
-
(2006)
Biochim Biophys Acta
, vol.1758
, Issue.3
, pp. 264-279
-
-
Pujals, S.1
Fernandez-Carneado, J.2
Lopez-Iglesias, C.3
Kogan, M.J.4
Giralt, E.5
-
33
-
-
0034090265
-
Blood-brain barrier transport of 125I-labeled basic fibroblast growth factor
-
Deguchi Y, Naito T, Yuge T, et al. Blood-brain barrier transport of 125I-labeled basic fibroblast growth factor. Pharm Res. 2000;17(1):63–69.
-
(2000)
Pharm Res
, vol.17
, Issue.1
, pp. 63-69
-
-
Deguchi, Y.1
Naito, T.2
Yuge, T.3
-
34
-
-
0037341140
-
Blood-brain barrier transport of a novel micro 1-specific opioid peptide, H-Tyr-D-Arg-Phe-beta-Ala-OH (TAPA)
-
Deguchi Y, Miyakawa Y, Sakurada S, et al. Blood-brain barrier transport of a novel micro 1-specific opioid peptide, H-Tyr-D-Arg-Phe-beta-Ala-OH (TAPA). J Neurochem. 2003;84(5):1154–1161.
-
(2003)
J Neurochem
, vol.84
, Issue.5
, pp. 1154-1161
-
-
Deguchi, Y.1
Miyakawa, Y.2
Sakurada, S.3
-
35
-
-
57149110011
-
CNS delivery via adsorptive transcytosis
-
Herve F, Ghinea N, Scherrmann JM. CNS delivery via adsorptive transcytosis. AAPS J. 2008;10(3):455–472.
-
(2008)
AAPS J
, vol.10
, Issue.3
, pp. 455-472
-
-
Herve, F.1
Ghinea, N.2
Scherrmann, J.M.3
-
36
-
-
33646461041
-
Drug and gene targeting to the brain via blood-brain barrier receptor-mediated transport systems
-
Pardridge WM. Drug and gene targeting to the brain via blood-brain barrier receptor-mediated transport systems. Int Congr Ser. 2005;1277(0):49–62.
-
(2005)
Int Congr Ser
, vol.1277
, pp. 49-62
-
-
Pardridge, W.M.1
-
37
-
-
34547637590
-
Drug targeting to the brain
-
Pardridge WM. Drug targeting to the brain. Pharm Res. 2007;24(9):1733–1744.
-
(2007)
Pharm Res
, vol.24
, Issue.9
, pp. 1733-1744
-
-
Pardridge, W.M.1
-
38
-
-
70449529637
-
Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases
-
Gabathuler R. Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases. Neurobiol Dis. 2010;37(1):48–57.
-
(2010)
Neurobiol Dis
, vol.37
, Issue.1
, pp. 48-57
-
-
Gabathuler, R.1
-
39
-
-
80053555632
-
Interplay of drug metabolizing CYP450 enzymes and ABC transporters in the blood-brain barrier
-
Decleves X, Jacob A, Yousif S, Shawahna R, Potin S, Scherrmann JM. Interplay of drug metabolizing CYP450 enzymes and ABC transporters in the blood-brain barrier. Curr Drug Metab. 2011;12(8):732–741.
-
(2011)
Curr Drug Metab
, vol.12
, Issue.8
, pp. 732-741
-
-
Decleves, X.1
Jacob, A.2
Yousif, S.3
Shawahna, R.4
Potin, S.5
Scherrmann, J.M.6
-
40
-
-
0027431164
-
Bone marrow-derived elements in the peripheral nervous system. An immunohistochemical and ultrastructural investigation in chimeric rats
-
Vass K, Hickey WF, Schmidt RE, Lassmann H. Bone marrow-derived elements in the peripheral nervous system. An immunohistochemical and ultrastructural investigation in chimeric rats. Lab Invest. 1993;69(3):275–282.
-
(1993)
Lab Invest
, vol.69
, Issue.3
, pp. 275-282
-
-
Vass, K.1
Hickey, W.F.2
Schmidt, R.E.3
Lassmann, H.4
-
42
-
-
0035685449
-
Complete characterization of the human ABC gene family
-
Dean M, Allikmets R. Complete characterization of the human ABC gene family. J Bioenerg Biomembr. 2001;33(6):475–479.
-
(2001)
J Bioenerg Biomembr
, vol.33
, Issue.6
, pp. 475-479
-
-
Dean, M.1
Allikmets, R.2
-
43
-
-
0034121122
-
Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes
-
Choo EF, Leake B, Wandel C, et al. Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes. Drug Metab Dispos. 2000;28(6):655–660.
-
(2000)
Drug Metab Dispos
, vol.28
, Issue.6
, pp. 655-660
-
-
Choo, E.F.1
Leake, B.2
Wandel, C.3
-
44
-
-
84893713788
-
Nanoscale drug delivery systems and the blood-brain barrier
-
Alyautdin R, Khalin I, Nafeeza MI, Haron MH, Kuznetsov D. Nanoscale drug delivery systems and the blood-brain barrier. Int J Nanomedicine. 2014;9:795–811.
-
(2014)
Int J Nanomedicine
, vol.9
, pp. 795-811
-
-
Alyautdin, R.1
Khalin, I.2
Nafeeza, M.I.3
Haron, M.H.4
Kuznetsov, D.5
-
45
-
-
0035141232
-
Pluronic P85 enhances the delivery of digoxin to the brain: In vitro and in vivo studies
-
Batrakova EV, Miller DW, Li S, Alakhov VY, Kabanov AV, Elmquist WF. Pluronic P85 enhances the delivery of digoxin to the brain: in vitro and in vivo studies. J Pharmacol Exp Ther. 2001;296(2):551–557.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, Issue.2
, pp. 551-557
-
-
Batrakova, E.V.1
Miller, D.W.2
Li, S.3
Alakhov, V.Y.4
Kabanov, A.V.5
Elmquist, W.F.6
-
46
-
-
60549115603
-
Effect of pluronic p85 on amino acid transport in bovine brain microvessel endothelial cells
-
Zhang X, Alakhova DY, Batrakova EV, et al. Effect of pluronic p85 on amino acid transport in bovine brain microvessel endothelial cells. J Neuroimmune Pharmacol. 2009;4(1):35–46.
-
(2009)
J Neuroimmune Pharmacol
, vol.4
, Issue.1
, pp. 35-46
-
-
Zhang, X.1
Alakhova, D.Y.2
Batrakova, E.V.3
-
47
-
-
17744382615
-
Effect of pluronic P85 on ATPase activity of drug efflux transporters
-
Batrakova EV, Li S, Li Y, Alakhov VY, Kabanov AV. Effect of pluronic P85 on ATPase activity of drug efflux transporters. Pharm Res. 2004;21(12):2226–2233.
-
(2004)
Pharm Res
, vol.21
, Issue.12
, pp. 2226-2233
-
-
Batrakova, E.V.1
Li, S.2
Li, Y.3
Alakhov, V.Y.4
Kabanov, A.V.5
-
48
-
-
0034757615
-
Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: Contributions of energy depletion and membrane fluidization
-
Batrakova EV, Li S, Vinogradov SV, Alakhov VY, Miller DW, Kabanov AV. Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane fluidization. J Pharmacol Exp Ther. 2001;299(2):483–493.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, Issue.2
, pp. 483-493
-
-
Batrakova, E.V.1
Li, S.2
Vinogradov, S.V.3
Alakhov, V.Y.4
Miller, D.W.5
Kabanov, A.V.6
-
49
-
-
0034729726
-
Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability
-
Bilsky EJ, Egleton RD, Mitchell SA, et al. Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability. J Med Chem. 2000;43(13):2586–2590.
-
(2000)
J Med Chem
, vol.43
, Issue.13
, pp. 2586-2590
-
-
Bilsky, E.J.1
Egleton, R.D.2
Mitchell, S.A.3
-
50
-
-
0034693398
-
Improved bioavailability to the brain of glycosylated Met-enkephalin analogs
-
Egleton RD, Mitchell SA, Huber JD, et al. Improved bioavailability to the brain of glycosylated Met-enkephalin analogs. Brain Res. 2000;881(1):37–46.
-
(2000)
Brain Res
, vol.881
, Issue.1
, pp. 37-46
-
-
Egleton, R.D.1
Mitchell, S.A.2
Huber, J.D.3
-
51
-
-
42049095153
-
Cell-penetrating peptides: From molecular mechanisms to therapeutics
-
Morris MC, Deshayes S, Heitz F, Divita G. Cell-penetrating peptides: from molecular mechanisms to therapeutics. Biol Cell. 2008;100(4):201–217.
-
(2008)
Biol Cell
, vol.100
, Issue.4
, pp. 201-217
-
-
Morris, M.C.1
Deshayes, S.2
Heitz, F.3
Divita, G.4
-
52
-
-
76749166383
-
Assessing the uptake kinetics and internalization mechanisms of cell-penetrating peptides using a quenched fluorescence assay
-
Mager I, Eiriksdottir E, Langel K, El Andaloussi S, Langel U. Assessing the uptake kinetics and internalization mechanisms of cell-penetrating peptides using a quenched fluorescence assay. Biochim Biophys Acta. 2010;1798(3):338–343.
-
(2010)
Biochim Biophys Acta
, vol.1798
, Issue.3
, pp. 338-343
-
-
Mager, I.1
Eiriksdottir, E.2
Langel, K.3
El Andaloussi, S.4
Langel, U.5
-
53
-
-
78651070758
-
Neuroprotection in stroke in the mouse with intravenous erythropoietin-Trojan horse fusion protein
-
Fu A, Hui EK, Lu JZ, Boado RJ, Pardridge WM. Neuroprotection in stroke in the mouse with intravenous erythropoietin-Trojan horse fusion protein. Brain Res. 2011;1369:203–207.
-
(2011)
Brain Res
, vol.1369
, pp. 203-207
-
-
Fu, A.1
Hui, E.K.2
Lu, J.Z.3
Boado, R.J.4
Pardridge, W.M.5
-
54
-
-
84895538642
-
An apolipoprotein E modified liposomal nanoparticle: Ligand dependent efficiency as a siRNA delivery carrier for mouse-derived brain endothelial cells
-
Tamaru M, Akita H, Kajimoto K, Sato Y, Hatakeyama H, Harashima H. An apolipoprotein E modified liposomal nanoparticle: ligand dependent efficiency as a siRNA delivery carrier for mouse-derived brain endothelial cells. Int J Pharm. 2014;465(1–2):77–82.
-
(2014)
Int J Pharm
, vol.465
, Issue.1-2
, pp. 77-82
-
-
Tamaru, M.1
Akita, H.2
Kajimoto, K.3
Sato, Y.4
Hatakeyama, H.5
Harashima, H.6
-
55
-
-
13844254266
-
Cell-penetrating peptides: Mechanism and kinetics of cargo delivery
-
Zorko M, Langel U. Cell-penetrating peptides: mechanism and kinetics of cargo delivery. Adv Drug Deliv Rev. 2005;57(4):529–545.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, Issue.4
, pp. 529-545
-
-
Zorko, M.1
Langel, U.2
-
56
-
-
0023200855
-
Absorptive-mediated endocytosis of cationized albumin and a beta-endorphin-cationized albumin chimeric peptide by isolated brain capillaries. Model system of blood-brain barrier transport
-
Kumagai AK, Eisenberg JB, Pardridge WM. Absorptive-mediated endocytosis of cationized albumin and a beta-endorphin-cationized albumin chimeric peptide by isolated brain capillaries. Model system of blood-brain barrier transport. J Biol Chem. 1987;262(31):15214–15219.
-
(1987)
J Biol Chem
, vol.262
, Issue.31
, pp. 15214-15219
-
-
Kumagai, A.K.1
Eisenberg, J.B.2
Pardridge, W.M.3
-
57
-
-
3142774800
-
Potential peptide carriers: Amphipathic proline-rich peptides derived from the N-terminal domain of gamma-zein
-
Fernandez-Carneado J, Kogan MJ, Castel S, Giralt E. Potential peptide carriers: amphipathic proline-rich peptides derived from the N-terminal domain of gamma-zein. Angew Chem Int Ed Engl. 2004;43(14):1811–1814.
-
(2004)
Angew Chem Int Ed Engl
, vol.43
, Issue.14
, pp. 1811-1814
-
-
Fernandez-Carneado, J.1
Kogan, M.J.2
Castel, S.3
Giralt, E.4
-
58
-
-
84898008648
-
Strategies to deliver peptide drugs to the brain
-
Lalatsa A, Schatzlein AG, Uchegbu IF. Strategies to deliver peptide drugs to the brain. Mol Pharm. 2014;11(4):1081–1093.
-
(2014)
Mol Pharm
, vol.11
, Issue.4
, pp. 1081-1093
-
-
Lalatsa, A.1
Schatzlein, A.G.2
Uchegbu, I.F.3
-
59
-
-
84862777853
-
The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2
-
Ren J, Shen S, Wang D, et al. The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2. Biomaterials. 2012;33(11):3324–3333.
-
(2012)
Biomaterials
, vol.33
, Issue.11
, pp. 3324-3333
-
-
Ren, J.1
Shen, S.2
Wang, D.3
-
60
-
-
84896749563
-
Delivering etoposide to the brain using catanionic solid lipid nanoparticles with surface 5-HT-moduline
-
Kuo YC, Hong TY. Delivering etoposide to the brain using catanionic solid lipid nanoparticles with surface 5-HT-moduline. Int J Pharm. 2014;465(1–2):132–142.
-
(2014)
Int J Pharm
, vol.465
, Issue.1-2
, pp. 132-142
-
-
Kuo, Y.C.1
Hong, T.Y.2
-
61
-
-
84888376188
-
A novel lactoferrin-modified beta-cyclodextrin nanocarrier for brain-targeting drug delivery
-
Ye Y, Sun Y, Zhao H, et al. A novel lactoferrin-modified beta-cyclodextrin nanocarrier for brain-targeting drug delivery. Int J Pharm. 2013;458(1):110–117.
-
(2013)
Int J Pharm
, vol.458
, Issue.1
, pp. 110-117
-
-
Ye, Y.1
Sun, Y.2
Zhao, H.3
-
63
-
-
34748829955
-
Diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles
-
Teixido M, Zurita E, Malakoutikhah M, Tarrago T, Giralt E. Diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles. J Am Chem Soc. 2007;129(38):11802–11813.
-
(2007)
J am Chem Soc
, vol.129
, Issue.38
, pp. 11802-11813
-
-
Teixido, M.1
Zurita, E.2
Malakoutikhah, M.3
Tarrago, T.4
Giralt, E.5
-
64
-
-
77949850475
-
N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles
-
Malakoutikhah M, Prades R, Teixido M, Giralt E. N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles. J Med Chem. 2010;53(6):2354–2363.
-
(2010)
J Med Chem
, vol.53
, Issue.6
, pp. 2354-2363
-
-
Malakoutikhah, M.1
Prades, R.2
Teixido, M.3
Giralt, E.4
-
65
-
-
77949492727
-
Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice
-
Lasagna-Reeves C, Gonzalez-Romero D, Barria MA, et al. Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice. Biochem Biophys Res Commun. 2010;393(4):649–655.
-
(2010)
Biochem Biophys Res Commun
, vol.393
, Issue.4
, pp. 649-655
-
-
Lasagna-Reeves, C.1
Gonzalez-Romero, D.2
Barria, M.A.3
-
66
-
-
57349139366
-
Biodistribution of 1.4- and 18-nm gold particles in rats
-
Semmler-Behnke M, Kreyling WG, Lipka J, et al. Biodistribution of 1.4- and 18-nm gold particles in rats. Small. 2008;4(12):2108–2111.
-
(2008)
Small
, vol.4
, Issue.12
, pp. 2108-2111
-
-
Semmler-Behnke, M.1
Kreyling, W.G.2
Lipka, J.3
-
67
-
-
50649113474
-
Biodistribution of colloidal gold nanoparticles after intravenous administration: Effect of particle size
-
Sonavane G, Tomoda K, Makino K. Biodistribution of colloidal gold nanoparticles after intravenous administration: effect of particle size. Colloids Surf B Biointerfaces. 2008;66(2):274–280.
-
(2008)
Colloids Surf B Biointerfaces
, vol.66
, Issue.2
, pp. 274-280
-
-
Sonavane, G.1
Tomoda, K.2
Makino, K.3
-
68
-
-
0032251605
-
Correlative instrumental neutron activation analysis, light microscopy, transmission electron microscopy, and X-ray microanalysis for qualitative and quantitative detection of colloidal gold spheres in biological specimens
-
Hillyer JF, Albrecht RM. Correlative instrumental neutron activation analysis, light microscopy, transmission electron microscopy, and X-ray microanalysis for qualitative and quantitative detection of colloidal gold spheres in biological specimens. Microsc Microanal. 1998;4(5):481–490.
-
(1998)
Microsc Microanal
, vol.4
, Issue.5
, pp. 481-490
-
-
Hillyer, J.F.1
Albrecht, R.M.2
-
69
-
-
0035206137
-
Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles
-
Hillyer JF, Albrecht RM. Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles. J Pharm Sci. 2001;90(12):1927–1936.
-
(2001)
J Pharm Sci
, vol.90
, Issue.12
, pp. 1927-1936
-
-
Hillyer, J.F.1
Albrecht, R.M.2
-
70
-
-
33644956110
-
Gold nanoparticles: A new X-ray contrast agent
-
Hainfeld JF, Slatkin DN, Focella TM, Smilowitz HM. Gold nanoparticles: a new X-ray contrast agent. Br J Radiol. 2006;79(939):248–253.
-
(2006)
Br J Radiol
, vol.79
, Issue.939
, pp. 248-253
-
-
Hainfeld, J.F.1
Slatkin, D.N.2
Focella, T.M.3
Smilowitz, H.M.4
-
71
-
-
37449017750
-
Kupffer cells are central in the removal of nanoparticles from the organism
-
Sadauskas E, Wallin H, Stoltenberg M, et al. Kupffer cells are central in the removal of nanoparticles from the organism. Part Fibre Toxicol. 2007;4:10.
-
(2007)
Part Fibre Toxicol
, vol.4
, pp. 10
-
-
Sadauskas, E.1
Wallin, H.2
Stoltenberg, M.3
-
72
-
-
39649115201
-
Particle size-dependent organ distribution of gold nanoparticles after intravenous administration
-
De Jong WH, Hagens WI, Krystek P, Burger MC, Sips AJ, Geertsma RE. Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials. 2008;29(12):1912–1919.
-
(2008)
Biomaterials
, vol.29
, Issue.12
, pp. 1912-1919
-
-
De Jong, W.H.1
Hagens, W.I.2
Krystek, P.3
Burger, M.C.4
Sips, A.J.5
Geertsma, R.E.6
-
73
-
-
78650101896
-
Size-dependent impairment of cognition in mice caused by the injection of gold nanoparticles
-
V. Chen YS, Hung YC, Lin LW, Liau I, Hong MY, Huang GS. Size-dependent impairment of cognition in mice caused by the injection of gold nanoparticles. Nanotechnology. 2010;21(48):485102.
-
(2010)
Nanotechnology
, vol.21
, Issue.48
-
-
Chen, Y.S.1
Hung, Y.C.2
Lin, L.W.3
Liau, I.4
Hong, M.Y.5
Huang, G.S.6
-
74
-
-
84866508055
-
Enhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound
-
Etame AB, Diaz RJ, O’Reilly MA, et al. Enhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound. Nanomedicine. 2012;8(7):1133–1142.
-
(2012)
Nanomedicine
, vol.8
, Issue.7
, pp. 1133-1142
-
-
Etame, A.B.1
Diaz, R.J.2
O’Reilly, M.A.3
-
75
-
-
84885145508
-
Gold nanoparticle imaging and radiotherapy of brain tumors in mice
-
Hainfeld JF, Smilowitz HM, O’Connor MJ, Dilmanian FA, Slatkin DN. Gold nanoparticle imaging and radiotherapy of brain tumors in mice. Nanomedicine (Lond). 2013;8(10):1601–1609.
-
(2013)
Nanomedicine (Lond)
, vol.8
, Issue.10
, pp. 1601-1609
-
-
Hainfeld, J.F.1
Smilowitz, H.M.2
O’Connor, M.J.3
Dilmanian, F.A.4
Slatkin, D.N.5
-
76
-
-
55749091647
-
Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
-
Lundqvist M, Stigler J, Elia G, Lynch I, Cedervall T, Dawson KA. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc Natl Acad Sci U S A. 2008;105(38):14265–14270.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.38
, pp. 14265-14270
-
-
Lundqvist, M.1
Stigler, J.2
Elia, G.3
Lynch, I.4
Cedervall, T.5
Dawson, K.A.6
-
77
-
-
77956215287
-
Modeling the time evolution of the nanoparticle-protein corona in a body fluid
-
Dell’Orco D, Lundqvist M, Oslakovic C, Cedervall T, Linse S. Modeling the time evolution of the nanoparticle-protein corona in a body fluid. PLoS One. 2010;5(6):e10949.
-
(2010)
Plos One
, vol.5
, Issue.6
-
-
Dell’Orco, D.1
Lundqvist, M.2
Oslakovic, C.3
Cedervall, T.4
Linse, S.5
-
78
-
-
84858591058
-
Identifying new therapeutic targets via modulation of protein corona formation by engineered nanoparticles
-
Arvizo RR, Giri K, Moyano D, et al. Identifying new therapeutic targets via modulation of protein corona formation by engineered nanoparticles. PLoS One. 2012;7(3):e33650.
-
(2012)
Plos One
, vol.7
, Issue.3
-
-
Arvizo, R.R.1
Giri, K.2
Moyano, D.3
-
79
-
-
79952302512
-
Physical-chemical aspects of protein corona: Relevance to in vitro and in vivo biological impacts of nanoparticles
-
Monopoli MP, Walczyk D, Campbell A, et al. Physical-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles. J Am Chem Soc. 2011;133(8):2525–2534.
-
(2011)
J am Chem Soc
, vol.133
, Issue.8
, pp. 2525-2534
-
-
Monopoli, M.P.1
Walczyk, D.2
Campbell, A.3
-
80
-
-
80053328840
-
Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: A comprehensive quantitative proteomic analysis
-
Tenzer S, Docter D, Rosfa S, et al. Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis. ACS Nano. 2011;5(9):7155–7167.
-
(2011)
ACS Nano
, vol.5
, Issue.9
, pp. 7155-7167
-
-
Tenzer, S.1
Docter, D.2
Rosfa, S.3
-
81
-
-
80053313445
-
The evolution of the protein corona around nanoparticles: A test study
-
Lundqvist M, Stigler J, Cedervall T, et al. The evolution of the protein corona around nanoparticles: a test study. ACS Nano. 2011;5(9):7503–7509.
-
(2011)
ACS Nano
, vol.5
, Issue.9
, pp. 7503-7509
-
-
Lundqvist, M.1
Stigler, J.2
Cedervall, T.3
-
82
-
-
51049108389
-
Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution
-
Dobrovolskaia MA, Aggarwal P, Hall JB, McNeil SE. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Mol Pharm. 2008;5(4):487–495.
-
(2008)
Mol Pharm
, vol.5
, Issue.4
, pp. 487-495
-
-
Dobrovolskaia, M.A.1
Aggarwal, P.2
Hall, J.B.3
McNeil, S.E.4
-
83
-
-
1342312020
-
Novel delivery systems for drug targeting to the brain
-
Reddy JS, Venkateswarlu V. Novel delivery systems for drug targeting to the brain. Drugs Future. 2004;29(1):63–83.
-
(2004)
Drugs Future
, vol.29
, Issue.1
, pp. 63-83
-
-
Reddy, J.S.1
Venkateswarlu, V.2
-
84
-
-
6344294066
-
Influence of the surface properties on nanoparticle-mediated transport of drugs to the brain
-
Kreuter J. Influence of the surface properties on nanoparticle-mediated transport of drugs to the brain. J Nanosci Nanotechnol. 2004;4(5):484–488.
-
(2004)
J Nanosci Nanotechnol
, vol.4
, Issue.5
, pp. 484-488
-
-
Kreuter, J.1
-
85
-
-
75749123084
-
Interaction of gold nanoparticles with common human blood proteins
-
Lacerda SH, Park JJ, Meuse C, et al. Interaction of gold nanoparticles with common human blood proteins. ACS Nano. 2010;4(1):365–379.
-
(2010)
ACS Nano
, vol.4
, Issue.1
, pp. 365-379
-
-
Lacerda, S.H.1
Park, J.J.2
Meuse, C.3
-
86
-
-
84891018929
-
Front matter, in blood-brain barriers: From ontogeny to artificial interfaces
-
Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, I–XXXII
-
Dermietzel R, Spray DC, Nedergaard M. Front matter, in blood-brain barriers: from ontogeny to artificial interfaces. Blood-Brain Barriers. Vol. 1. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA; 2007:I–XXXII.
-
(2007)
Blood-Brain Barriers
, vol.1
-
-
Dermietzel, R.1
Spray, D.C.2
Nedergaard, M.3
-
87
-
-
84901473966
-
Drug delivery to the central nervous system by polymeric nanoparticles: What do we know?
-
Kreuter J. Drug delivery to the central nervous system by polymeric nanoparticles: what do we know? Adv Drug Deliv Rev. 2013;71:2–14.
-
(2013)
Adv Drug Deliv Rev
, vol.71
, pp. 2-14
-
-
Kreuter, J.1
-
88
-
-
79959310261
-
PEO-PPO block copolymers for passive micellar targeting and overcoming multidrug resistance in cancer therapy
-
Alvarez-Lorenzo C, Sosnik A, Concheiro A. PEO-PPO block copolymers for passive micellar targeting and overcoming multidrug resistance in cancer therapy. Curr Drug Targets. 2011;12(8):1112–1130.
-
(2011)
Curr Drug Targets
, vol.12
, Issue.8
, pp. 1112-1130
-
-
Alvarez-Lorenzo, C.1
Sosnik, A.2
Concheiro, A.3
-
89
-
-
34547655840
-
Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration
-
Gao X, Wu B, Zhang Q, et al. Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration. J Control Release. 2007;121(3):156–167.
-
(2007)
J Control Release
, vol.121
, Issue.3
, pp. 156-167
-
-
Gao, X.1
Wu, B.2
Zhang, Q.3
-
90
-
-
80054697226
-
Brain-targeted delivery of paclitaxel using glutathione-coated nanoparticles for brain cancers
-
Geldenhuys W, Mbimba T, Bui T, Harrison K, Sutariya V. Brain-targeted delivery of paclitaxel using glutathione-coated nanoparticles for brain cancers. J Drug Target. 2011;19(9):837–845.
-
(2011)
J Drug Target
, vol.19
, Issue.9
, pp. 837-845
-
-
Geldenhuys, W.1
Mbimba, T.2
Bui, T.3
Harrison, K.4
Sutariya, V.5
-
91
-
-
79960167888
-
Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: Preparation, characterization and efficacy in Parkinson’s disease
-
Hu K, Shi Y, Jiang W, Han J, Huang S, Jiang X. Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: preparation, characterization and efficacy in Parkinson’s disease. Int J Pharm. 2011;415(1–2):273–283.
-
(2011)
Int J Pharm
, vol.415
, Issue.1-2
, pp. 273-283
-
-
Hu, K.1
Shi, Y.2
Jiang, W.3
Han, J.4
Huang, S.5
Jiang, X.6
-
92
-
-
84870363825
-
F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery
-
Hu Q, Gu G, Liu Z, et al. F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery. Biomaterials. 2013;34(4):1135–1145.
-
(2013)
Biomaterials
, vol.34
, Issue.4
, pp. 1135-1145
-
-
Hu, Q.1
Gu, G.2
Liu, Z.3
-
93
-
-
79960561767
-
Dual targeting effect of angiopep-2-modified, DNA-loaded nanoparticles for glioma
-
Huang S, Li J, Han L, et al. Dual targeting effect of angiopep-2-modified, DNA-loaded nanoparticles for glioma. Biomaterials. 2011;32(28):6832–6838.
-
(2011)
Biomaterials
, vol.32
, Issue.28
, pp. 6832-6838
-
-
Huang, S.1
Li, J.2
Han, L.3
-
94
-
-
84883756054
-
Delivery of siRNA to the brain using a combination of nose-to-brain delivery and cell-penetrating peptide-modified nano-micelles
-
Kanazawa T, Akiyama F, Kakizaki S, Takashima Y, Seta Y. Delivery of siRNA to the brain using a combination of nose-to-brain delivery and cell-penetrating peptide-modified nano-micelles. Biomaterials. 2013;34(36):9220–9226.
-
(2013)
Biomaterials
, vol.34
, Issue.36
, pp. 9220-9226
-
-
Kanazawa, T.1
Akiyama, F.2
Kakizaki, S.3
Takashima, Y.4
Seta, Y.5
-
95
-
-
70350200866
-
Gene delivery targeted to the brain using an angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer
-
Ke W, Shao K, Huang R, et al. Gene delivery targeted to the brain using an angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer. Biomaterials. 2009;30(36):6976–6985.
-
(2009)
Biomaterials
, vol.30
, Issue.36
, pp. 6976-6985
-
-
Ke, W.1
Shao, K.2
Huang, R.3
-
96
-
-
84870386548
-
Brain-targeted delivery of protein using chitosan- and RVG peptide-conjugated, pluronic-based nano-carrier
-
Kim JY, Choi WI, Kim YH, Tae G. Brain-targeted delivery of protein using chitosan- and RVG peptide-conjugated, pluronic-based nano-carrier. Biomaterials. 2013;34(4):1170–1178.
-
(2013)
Biomaterials
, vol.34
, Issue.4
, pp. 1170-1178
-
-
Kim, J.Y.1
Choi, W.I.2
Kim, Y.H.3
Tae, G.4
-
97
-
-
84884162825
-
T7 peptide-functionalized nanoparticles utilizing RNA interference for glioma dual targeting
-
Kuang Y, An S, Guo Y, et al. T7 peptide-functionalized nanoparticles utilizing RNA interference for glioma dual targeting. Int J Pharm. 2013;454(1):11–20.
-
(2013)
Int J Pharm
, vol.454
, Issue.1
, pp. 11-20
-
-
Kuang, Y.1
An, S.2
Guo, Y.3
-
98
-
-
80051783785
-
Transport of saquinavir across human brain-microvascular endothelial cells by poly(Lactide-co-glycolide) nanoparticles with surface poly-(gamma-glutamic acid)
-
Kuo YC, Yu HW. Transport of saquinavir across human brain-microvascular endothelial cells by poly(lactide-co-glycolide) nanoparticles with surface poly-(gamma-glutamic acid). Int J Pharm. 2011;416(1):365–375.
-
(2011)
Int J Pharm
, vol.416
, Issue.1
, pp. 365-375
-
-
Kuo, Y.C.1
Yu, H.W.2
-
99
-
-
84878867162
-
Brain delivery of NAP with PEG-PLGA nanoparticles modified with phage display peptides
-
Li J, Zhang C, Li J, et al. Brain delivery of NAP with PEG-PLGA nanoparticles modified with phage display peptides. Pharm Res. 2013;30(7):1813–1823.
-
(2013)
Pharm Res
, vol.30
, Issue.7
, pp. 1813-1823
-
-
Li, J.1
Zhang, C.2
Li, J.3
-
100
-
-
38549180565
-
Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier
-
Liu L, Guo K, Lu J, et al. Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier. Biomaterials. 2008;29(10):1509–1517.
-
(2008)
Biomaterials
, vol.29
, Issue.10
, pp. 1509-1517
-
-
Liu, L.1
Guo, K.2
Lu, J.3
-
101
-
-
58149185965
-
Polymeric micelles anchored with TAT for delivery of antibiotics across the blood-brain barrier
-
Liu L, Venkatraman SS, Yang YY, et al. Polymeric micelles anchored with TAT for delivery of antibiotics across the blood-brain barrier. Biopolymers. 2008;90(5):617–623.
-
(2008)
Biopolymers
, vol.90
, Issue.5
, pp. 617-623
-
-
Liu, L.1
Venkatraman, S.S.2
Yang, Y.Y.3
-
102
-
-
84877660877
-
Targeting caspase-3 as dual therapeutic benefits by RNAi facilitating brain-targeted nanoparticles in a rat model of Parkinson’s disease
-
Liu Y, Guo Y, An S, et al. Targeting caspase-3 as dual therapeutic benefits by RNAi facilitating brain-targeted nanoparticles in a rat model of Parkinson’s disease. PLoS One. 2013;8(5):e62905.
-
(2013)
Plos One
, vol.8
, Issue.5
-
-
Liu, Y.1
Guo, Y.2
An, S.3
-
103
-
-
84879373733
-
B6 peptide-modified PEG-PLA nanoparticles for enhanced brain delivery of neuroprotective peptide
-
Liu Z, Gao X, Kang T, et al. B6 peptide-modified PEG-PLA nanoparticles for enhanced brain delivery of neuroprotective peptide. Bioconjug Chem. 2013;24(6):997–1007.
-
(2013)
Bioconjug Chem
, vol.24
, Issue.6
, pp. 997-1007
-
-
Liu, Z.1
Gao, X.2
Kang, T.3
-
104
-
-
84874971833
-
Lactoferrin-modified PEG-co-PCL nanoparticles for enhanced brain delivery of NAP peptide following intranasal administration
-
Liu Z, Jiang M, Kang T, et al. Lactoferrin-modified PEG-co-PCL nanoparticles for enhanced brain delivery of NAP peptide following intranasal administration. Biomaterials. 2013;34(15):3870–3881.
-
(2013)
Biomaterials
, vol.34
, Issue.15
, pp. 3870-3881
-
-
Liu, Z.1
Jiang, M.2
Kang, T.3
-
105
-
-
84857694629
-
Curcumin loaded-PLGA nanoparticles conjugated with Tet-1 peptide for potential use in Alzheimer’s disease
-
Mathew A, Fukuda T, Nagaoka Y, et al. Curcumin loaded-PLGA nanoparticles conjugated with Tet-1 peptide for potential use in Alzheimer’s disease. PLoS One. 2012;7(3):e32616.
-
(2012)
Plos One
, vol.7
, Issue.3
-
-
Mathew, A.1
Fukuda, T.2
Nagaoka, Y.3
-
106
-
-
33745226168
-
Gene delivery to differentiated neurotypic cells with RGD and HIV Tat peptide functionalized polymeric nanoparticles
-
Suk JS, Suh J, Choy K, Lai SK, Fu J, Hanes J. Gene delivery to differentiated neurotypic cells with RGD and HIV Tat peptide functionalized polymeric nanoparticles. Biomaterials. 2006;27(29):5143–5150.
-
(2006)
Biomaterials
, vol.27
, Issue.29
, pp. 5143-5150
-
-
Suk, J.S.1
Suh, J.2
Choy, K.3
Lai, S.K.4
Fu, J.5
Hanes, J.6
-
107
-
-
84875898060
-
Tat peptide-decorated gelatin-siloxane nanoparticles for delivery of CGRP transgene in treatment of cerebral vasospasm
-
Tian XH, Wang ZG, Meng H, et al. Tat peptide-decorated gelatin-siloxane nanoparticles for delivery of CGRP transgene in treatment of cerebral vasospasm. Int J Nanomedicine. 2013;8:865–876.
-
(2013)
Int J Nanomedicine
, vol.8
, pp. 865-876
-
-
Tian, X.H.1
Wang, Z.G.2
Meng, H.3
-
108
-
-
34548041658
-
Targeting the central nervous system: In vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123
-
Tosi G, Costantino L, Rivasi F, et al. Targeting the central nervous system: in vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123. J Control Release. 2007;122(1):1–9.
-
(2007)
J Control Release
, vol.122
, Issue.1
, pp. 1-9
-
-
Tosi, G.1
Costantino, L.2
Rivasi, F.3
-
109
-
-
84865558062
-
Anti-glioblastoma efficacy and safety of paclitaxel-loading angiopep-conjugated dual targeting PEG-PCL nanoparticles
-
Xin H, Sha X, Jiang X, Zhang W, Chen L, Fang X. Anti-glioblastoma efficacy and safety of paclitaxel-loading angiopep-conjugated dual targeting PEG-PCL nanoparticles. Biomaterials. 2012;33(32):8167–8176.
-
(2012)
Biomaterials
, vol.33
, Issue.32
, pp. 8167-8176
-
-
Xin, H.1
Sha, X.2
Jiang, X.3
Zhang, W.4
Chen, L.5
Fang, X.6
-
110
-
-
77956079867
-
Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide
-
Guerrero S, Araya E, Fiedler JL, et al. Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide. Nanomedicine. 2010;5(6):897–913.
-
(2010)
Nanomedicine
, vol.5
, Issue.6
, pp. 897-913
-
-
Guerrero, S.1
Araya, E.2
Fiedler, J.L.3
-
111
-
-
84858742858
-
Synthesis and in vivo evaluation of the biodistribution of a 18F-labeled conjugate gold-nanoparticle-peptide with potential biomedical application
-
Guerrero S, Herance JR, Rojas S, et al. Synthesis and in vivo evaluation of the biodistribution of a 18F-labeled conjugate gold-nanoparticle-peptide with potential biomedical application. Bioconjug Chem. 2012;23(3):399–408.
-
(2012)
Bioconjug Chem
, vol.23
, Issue.3
, pp. 399-408
-
-
Guerrero, S.1
Herance, J.R.2
Rojas, S.3
-
112
-
-
0031873102
-
Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer’s therapy
-
Soto C, Sigurdsson EM, Morelli L, Kumar RA, Castano EM, Frangione B. Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer’s therapy. Nat Med. 1998;4(7):822–826.
-
(1998)
Nat Med
, vol.4
, Issue.7
, pp. 822-826
-
-
Soto, C.1
Sigurdsson, E.M.2
Morelli, L.3
Kumar, R.A.4
Castano, E.M.5
Frangione, B.6
-
113
-
-
7644225312
-
RAGE (Yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier
-
Deane R, Wu Z, Zlokovic BV. RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier. Stroke. 2004;35(11 suppl 1):2628–2631.
-
(2004)
Stroke
, vol.35
, Issue.11
, pp. 2628-2631
-
-
Deane, R.1
Wu, Z.2
Zlokovic, B.V.3
-
114
-
-
0037703255
-
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain
-
Deane R, Du Yan S, Submamaryan RK, et al. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nat Med. 2003;9(7):907–913.
-
(2003)
Nat Med
, vol.9
, Issue.7
, pp. 907-913
-
-
Deane, R.1
Du Yan, S.2
Submamaryan, R.K.3
-
115
-
-
84864313094
-
Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor
-
Prades R, Guerrero S, Araya E, et al. Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor. Biomaterials. 2012;33(29):7194–7205.
-
(2012)
Biomaterials
, vol.33
, Issue.29
, pp. 7194-7205
-
-
Prades, R.1
Guerrero, S.2
Araya, E.3
-
116
-
-
84868101856
-
Vascular-targeted photothermal therapy of an orthotopic murine glioma model
-
Day ES, Zhang L, Thompson PA, et al. Vascular-targeted photothermal therapy of an orthotopic murine glioma model. Nanomedicine. 2012;7(8):1133–1148.
-
(2012)
Nanomedicine
, vol.7
, Issue.8
, pp. 1133-1148
-
-
Day, E.S.1
Zhang, L.2
Thompson, P.A.3
-
117
-
-
84878206104
-
Nanoparticle targeting to neurons in a rat hippocampal slice culture model
-
Walters R, Kraig RP, Medintz I, et al. Nanoparticle targeting to neurons in a rat hippocampal slice culture model. ASN Neuro. 2012;4(6):383–392.
-
(2012)
ASN Neuro
, vol.4
, Issue.6
, pp. 383-392
-
-
Walters, R.1
Kraig, R.P.2
Medintz, I.3
-
118
-
-
84884388358
-
Age-dependent effects of microglial inhibition in vivo on Alzheimer’s disease neuropathology using bioactive-conjugated iron oxide nanoparticles
-
Glat M, Skaat H, Menkes-Caspi N, Margel S, Stern EA. Age-dependent effects of microglial inhibition in vivo on Alzheimer’s disease neuropathology using bioactive-conjugated iron oxide nanoparticles. J Nanobiotechnology. 2013;11:32.
-
(2013)
J Nanobiotechnology
, vol.11
, pp. 32
-
-
Glat, M.1
Skaat, H.2
Menkes-Caspi, N.3
Margel, S.4
Stern, E.A.5
-
119
-
-
84885576795
-
Gold nanoparticles functionalized with a fragment of the neural cell adhesion molecule L1 stimulate L1-mediated functions
-
Schulz F, Lutz D, Rusche N, et al. Gold nanoparticles functionalized with a fragment of the neural cell adhesion molecule L1 stimulate L1-mediated functions. Nanoscale. 2013;5(21):10605–10617.
-
(2013)
Nanoscale
, vol.5
, Issue.21
, pp. 10605-10617
-
-
Schulz, F.1
Lutz, D.2
Rusche, N.3
-
120
-
-
84874516217
-
Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer’s disease transgenic mice using magnetic resonance microimaging
-
Wadghiri YZ, Li J, Wang J, et al. Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer’s disease transgenic mice using magnetic resonance microimaging. PLoS One. 2013;8(2):e57097.
-
(2013)
Plos One
, vol.8
, Issue.2
-
-
Wadghiri, Y.Z.1
Li, J.2
Wang, J.3
-
121
-
-
80053349963
-
Effects of photoacoustic imaging and photothermal ablation therapy mediated by targeted hollow gold nanospheres in an orthotopic mouse xenograft model of glioma
-
Lu W, Melancon MP, Xiong C, et al. Effects of photoacoustic imaging and photothermal ablation therapy mediated by targeted hollow gold nanospheres in an orthotopic mouse xenograft model of glioma. Cancer Res. 2011;71(19):6116–6121.
-
(2011)
Cancer Res
, vol.71
, Issue.19
, pp. 6116-6121
-
-
Lu, W.1
Melancon, M.P.2
Xiong, C.3
-
122
-
-
84892161991
-
Penades S. 68Ga-labeled gold glyconanoparticles for exploring blood-brain barrier permeability: Preparation, biodistribution studies, and improved brain uptake via neuropeptide conjugation
-
Frigell J, Garcia I, Gomez-Vallejo V, Llop J, Penades S. 68Ga-labeled gold glyconanoparticles for exploring blood-brain barrier permeability: preparation, biodistribution studies, and improved brain uptake via neuropeptide conjugation. J Am Chem Soc. 2014;136(1):449–457.
-
(2014)
J am Chem Soc
, vol.136
, Issue.1
, pp. 449-457
-
-
Frigell, J.1
Garcia, I.2
Gomez-Vallejo, V.3
Llop, J.4
-
123
-
-
79955409570
-
Novel 18F-labeled benzofuran derivatives with improved properties for positron emission tomography (PET) imaging of beta-amyloid plaques in Alzheimer’s brains
-
Ono M, Cheng Y, Kimura H, et al. Novel 18F-labeled benzofuran derivatives with improved properties for positron emission tomography (PET) imaging of beta-amyloid plaques in Alzheimer’s brains. J Med Chem. 2011;54(8):2971–2979.
-
(2011)
J Med Chem
, vol.54
, Issue.8
, pp. 2971-2979
-
-
Ono, M.1
Cheng, Y.2
Kimura, H.3
-
124
-
-
84893698840
-
Blood protein coating of gold nanoparticles as potential tool for organ targeting
-
Schäffler M, Sousa F, Wenk A, et al. Blood protein coating of gold nanoparticles as potential tool for organ targeting. Biomaterials. 2014;35(10):3455–3466.
-
(2014)
Biomaterials
, vol.35
, Issue.10
, pp. 3455-3466
-
-
Schäffler, M.1
Sousa, F.2
Wenk, A.3
-
125
-
-
84893287460
-
Transport of nanoparticles through the blood-brain barrier for imaging and therapeutic applications
-
Shilo M, Motiei M, Hana P, Popovtzer R. Transport of nanoparticles through the blood-brain barrier for imaging and therapeutic applications. Nanoscale. 2014;6(4):2146–2152.
-
(2014)
Nanoscale
, vol.6
, Issue.4
, pp. 2146-2152
-
-
Shilo, M.1
Motiei, M.2
Hana, P.3
Popovtzer, R.4
-
126
-
-
84891622489
-
Gold nanoparticle-membrane interactions: Implications in biomedicine
-
Riveros A, Dadlani K, Salas E, Caballero L, Melo F, Kogan MJ. Gold nanoparticle-membrane interactions: implications in biomedicine. J Biomater Tissue Eng. 2013;3(1):4–21.
-
(2013)
J Biomater Tissue Eng
, vol.3
, Issue.1
, pp. 4-21
-
-
Riveros, A.1
Dadlani, K.2
Salas, E.3
Caballero, L.4
Melo, F.5
Kogan, M.J.6
-
127
-
-
45749115053
-
How changes in the sequence of the peptide CLPFFD-NH2 can modify the conjugation and stability of gold nanoparticles and their affinity for beta-amyloid fibrils
-
Olmedo I, Araya E, Sanz F, et al. How changes in the sequence of the peptide CLPFFD-NH2 can modify the conjugation and stability of gold nanoparticles and their affinity for beta-amyloid fibrils. Bioconjug Chem. 2008;19(6):1154–1163.
-
(2008)
Bioconjug Chem
, vol.19
, Issue.6
, pp. 1154-1163
-
-
Olmedo, I.1
Araya, E.2
Sanz, F.3
-
128
-
-
16244385641
-
Solid-state NMR structural studies of peptides immobilized on gold nanoparticles
-
Bower PV, Louie EA, Long JR, Stayton PS, Drobny GP. Solid-state NMR structural studies of peptides immobilized on gold nanoparticles. Langmuir. 2005;21(7):3002–3007.
-
(2005)
Langmuir
, vol.21
, Issue.7
, pp. 3002-3007
-
-
Bower, P.V.1
Louie, E.A.2
Long, J.R.3
Stayton, P.S.4
Drobny, G.P.5
-
129
-
-
34548165708
-
Infrared spectroscopy of proteins
-
Barth A. Infrared spectroscopy of proteins. Biochim Biophys Acta. 2007;1767(9):1073–1101.
-
(2007)
Biochim Biophys Acta
, vol.1767
, Issue.9
, pp. 1073-1101
-
-
Barth, A.1
-
130
-
-
84874085789
-
Amide I vibrational mode suppression in surface (SERS) and tip (TERS) enhanced Raman spectra of protein specimens
-
Kurouski D, Postiglione T, Deckert-Gaudig T, Deckert V, Lednev IK. Amide I vibrational mode suppression in surface (SERS) and tip (TERS) enhanced Raman spectra of protein specimens. Analyst. 2013;138(6):1665–1673.
-
(2013)
Analyst
, vol.138
, Issue.6
, pp. 1665-1673
-
-
Kurouski, D.1
Postiglione, T.2
Deckert-Gaudig, T.3
Deckert, V.4
Lednev, I.K.5
-
131
-
-
84880249341
-
Analysis of protein acetyltransferase structure-function relation by surface-enhanced Raman scattering (SERS): A tool to screen and characterize small molecule modulators
-
Hake SB, Janzen CJ, editors, Humana Press
-
Arif M, Karthigeyan D, Siddhanta S, Kumar GVP, Narayana C, Kundu T. Analysis of protein acetyltransferase structure-function relation by surface-enhanced Raman scattering (SERS): a tool to screen and characterize small molecule modulators. In: Hake SB, Janzen CJ, editors. Protein Acetylation. Vol. 981. Humana Press; 2013:239–261.
-
(2013)
Protein Acetylation
, vol.981
, pp. 239-261
-
-
Arif, M.1
Karthigeyan, D.2
Siddhanta, S.3
Kumar, G.4
Narayana, C.5
Kundu, T.6
-
132
-
-
77953912416
-
Strategy for effective brain drug delivery
-
Alam MI, Beg S, Samad A, et al. Strategy for effective brain drug delivery. Eur J Pharm Sci. 2010;40(5):385–403.
-
(2010)
Eur J Pharm Sci
, vol.40
, Issue.5
, pp. 385-403
-
-
Alam, M.I.1
Beg, S.2
Samad, A.3
-
133
-
-
84870203193
-
Anatomical and histological factors affecting intranasal drug and vaccine delivery
-
Gizurarson S. Anatomical and histological factors affecting intranasal drug and vaccine delivery. Curr Drug Deliv. 2012;9(6):566–582.
-
(2012)
Curr Drug Deliv
, vol.9
, Issue.6
, pp. 566-582
-
-
Gizurarson, S.1
-
134
-
-
0037459005
-
Nasal drug delivery – possibilities, problems and solutions
-
Illum L. Nasal drug delivery – possibilities, problems and solutions. J Control Release. 2003;87(1–3):187–198.
-
(2003)
J Control Release
, vol.87
, Issue.1-3
, pp. 187-198
-
-
Illum, L.1
-
135
-
-
68649090916
-
Nanoparticles for direct nose-to-brain delivery of drugs
-
Mistry A, Stolnik S, Illum L. Nanoparticles for direct nose-to-brain delivery of drugs. Int J Pharm. 2009;379(1):146–157.
-
(2009)
Int J Pharm
, vol.379
, Issue.1
, pp. 146-157
-
-
Mistry, A.1
Stolnik, S.2
Illum, L.3
-
137
-
-
30344469072
-
Gold nanoparticles as carriers for efficient transmucosal insulin delivery
-
Joshi HM, Bhumkar DR, Joshi K, Pokharkar V, Sastry M. Gold nanoparticles as carriers for efficient transmucosal insulin delivery. Langmuir. 2006;22(1):300–305.
-
(2006)
Langmuir
, vol.22
, Issue.1
, pp. 300-305
-
-
Joshi, H.M.1
Bhumkar, D.R.2
Joshi, K.3
Pokharkar, V.4
Sastry, M.5
-
138
-
-
77952932220
-
Microglial response to gold nanoparticles
-
Hutter E, Boridy S, Labrecque S, et al. Microglial response to gold nanoparticles. ACS Nano. 2010;4(5):2595–2606.
-
(2010)
ACS Nano
, vol.4
, Issue.5
, pp. 2595-2606
-
-
Hutter, E.1
Boridy, S.2
Labrecque, S.3
-
139
-
-
84904310183
-
Quantitative analysis of drug delivery to the brain via nasal route
-
Kozlovskaya L, Abou-Kaoud M, Stepensky D. Quantitative analysis of drug delivery to the brain via nasal route. J Control Release. 2014;189:133–140.
-
(2014)
J Control Release
, vol.189
, pp. 133-140
-
-
Kozlovskaya, L.1
Abou-Kaoud, M.2
Stepensky, D.3
-
140
-
-
0037107001
-
Permeability issues in nasal drug delivery
-
Arora P, Sharma S, Garg S. Permeability issues in nasal drug delivery. Drug Discov Today. 2002;7(18):967–975.
-
(2002)
Drug Discov Today
, vol.7
, Issue.18
, pp. 967-975
-
-
Arora, P.1
Sharma, S.2
Garg, S.3
-
141
-
-
84863203317
-
Uptake and cytotoxicity of citrate-coated gold nanospheres: Comparative studies on human endothelial and epithelial cells
-
Freese C, Uboldi C, Gibson MI, et al. Uptake and cytotoxicity of citrate-coated gold nanospheres: comparative studies on human endothelial and epithelial cells. Part Fibre Toxicol. 2012;9:23.
-
(2012)
Part Fibre Toxicol
, vol.9
-
-
Freese, C.1
Uboldi, C.2
Gibson, M.I.3
|