Improved bioavailability to the brain of glycosylated Met-enkephalin analogs

Brain Research

Volumn 881, Issue 1, 2000, Pages 37-46

  Egleton, Richard D ^a   Mitchell, Scott A ^b   Huber, Jason D ^a   Janders, Jaqueline ^a   Stropova, Dagmar ^a   Polt, Robin ^b   Yamamura, Henry I ^a   Hruby, Victor J ^b   Davis, Thomas P ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b University of Arizona   (United States)

Author keywords

Antinociception; Bioavailability; Blood brain barrier; Cellular and molecular biology; Peptide; Structure activity

Indexed keywords

DELTA OPIATE RECEPTOR; ENKEPHALIN DERIVATIVE; MU OPIATE RECEPTOR;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; BRAIN PERFUSION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; FEMALE; GLYCOSYLATION; LIPOPHILICITY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ANIMAL; BIOLOGICAL AVAILABILITY; BLOOD-BRAIN BARRIER; BRAIN; CATTLE; ENKEPHALIN, METHIONINE; FEMALE; GLYCOSYLATION; MALE; MICE; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, DELTA; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0034693398     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02794-3     Document Type: Article

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