Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability

Journal of Medicinal Chemistry

Volumn 43, Issue 13, 2000, Pages 2586-2590

  Bilsky, Edward J ^a   Egleton, Richard D ^b   Mitchell, Scott A ^c   Palian, Michael M ^c   Davis, Peg ^b   Huber, Jason D ^b   Jones, Heather ^a   Yamamura, Henry I ^b   Janders, Jacqueline ^b   Davis, Thomas P ^b   Porreca, Frank ^b   Hruby, Victor J ^c   Polt, Robin ^c  

^a UNIVERSITY OF NORTHERN COLORADO   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN DERIVATIVE; GLYCOPEPTIDE; MORPHINE; NALOXONE;

ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN FUNCTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DEPENDENCE; DRUG PENETRATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; FEMALE; NONHUMAN; RAT;

ANALGESICS, OPIOID; ANIMALS; BLOOD-BRAIN BARRIER; ENKEPHALIN, LEUCINE; FEMALE; GLYCOPEPTIDES; INJECTIONS, INTRAVENTRICULAR; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0034729726     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000077y     Document Type: Article

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