-
2
-
-
84949257630
-
Depletion of fat-resident Treg cells prevents age-Associated insulin resistance
-
Bapat S. P., et al. Depletion of fat-resident Treg cells prevents age-Associated insulin resistance. Nature 528, 137-141 (2015
-
(2015)
Nature
, vol.528
, pp. 137-141
-
-
Bapat, S.P.1
-
3
-
-
84864659280
-
Long-Term risk of incident type 2 diabetes and measures of overall and regional obesity: The EPIC-InterAct case-cohort study
-
Langenberg, C., et al. Long-Term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study. PLoS Med. 9, e1001230 (2012
-
(2012)
PLoS Med
, vol.9
, pp. e1001230
-
-
Langenberg, C.1
-
4
-
-
84906882822
-
Global, regional, and national prevalence of overweight and obesity in children and adults during 1980 2013: A systematic analysis for the global burden of disease study 2013
-
Ng, M., et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980 2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 384, 766-781 (2014
-
(2014)
Lancet
, vol.384
, pp. 766-781
-
-
Ng, M.1
-
5
-
-
84880795072
-
The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: A pooled analysis
-
Singh, G. M., et al. The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS ONE 8, e65174 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e65174
-
-
Singh, G.M.1
-
6
-
-
78649747039
-
Body-mass index and mortality among 1.46 million white adults
-
Berrington de Gonzalez, A., et al. Body-mass index and mortality among 1.46 million white adults. N. Engl. J. Med. 363, 2211-2219 (2010
-
(2010)
N. Engl. J. Med
, vol.363
, pp. 2211-2219
-
-
Berrington De Gonzalez, A.1
-
7
-
-
38149142887
-
-
no authors listed]. WHO
-
authors listed]. Diabetes Fact Sheet. WHO http://www.who.int/mediacentre/factsheets/fs312/en/(2015
-
(2015)
Diabetes Fact Sheet
-
-
-
8
-
-
84937216336
-
Association of cardiometabolic multimorbidity with mortality
-
Di Angelantonio E., et al. Association of cardiometabolic multimorbidity with mortality. JAMA 314, 52-60 (2015
-
(2015)
JAMA
, vol.314
, pp. 52-60
-
-
Di Angelantonio, E.1
-
9
-
-
84949086655
-
Global, regional, and national disability-Adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990 2013: Quantifying the epidemiological transition
-
Murray C. J., et al. Global, regional, and national disability-Adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990 2013: quantifying the epidemiological transition. Lancet http://dx.doi.org/10.1016/s0140-6736(15)61340-x 2015
-
(2015)
Lancet
-
-
Murray, C.J.1
-
10
-
-
84924271853
-
Global cancer statistics, 2012
-
Torre, L. A., et al. Global cancer statistics, 2012. CA Cancer J. Clin. 65, 87-108 (2015
-
(2015)
CA Cancer J. Clin
, vol.65
, pp. 87-108
-
-
Torre, L.A.1
-
11
-
-
84895832615
-
Global estimates of diabetes prevalence for 2013 and projections for 2035
-
Guariguata, L., et al. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res. Clin. Pract. 103, 137-149 (2014
-
(2014)
Diabetes Res. Clin. Pract
, vol.103
, pp. 137-149
-
-
Guariguata, L.1
-
12
-
-
84988904805
-
Prevalence of obesity among adults and youth: United States, 2011-2014
-
Ogden C. L., Carroll, M. D., Fryar, C. D., & Flegal, K. M. Prevalence of obesity among adults and youth: United States, 2011-2014. NCHS Data Brief 1-8 2015
-
(2015)
NCHS Data Brief
, pp. 1-8
-
-
Ogden, C.L.1
Carroll, M.D.2
Fryar, C.D.3
Flegal, K.M.4
-
13
-
-
84860663487
-
The descriptive epidemiology of female breast cancer: An international comparison of screening, incidence, survival and mortality
-
Youlden, D. R., et al. The descriptive epidemiology of female breast cancer: an international comparison of screening, incidence, survival and mortality. Cancer Epidemiol. 36, 237-248 (2012
-
(2012)
Cancer Epidemiol
, vol.36
, pp. 237-248
-
-
Youlden, D.R.1
-
14
-
-
84924910144
-
Global burden of cancer attributable to high body-mass index in 2012: A population-based study
-
Arnold, M., et al. Global burden of cancer attributable to high body-mass index in 2012: a population-based study. Lancet Oncol. 16, 36-46 (2015
-
(2015)
Lancet Oncol
, vol.16
, pp. 36-46
-
-
Arnold, M.1
-
15
-
-
0036800143
-
The contribution of fat and fat-free tissue to body mass index in contemporary children and the reference child
-
Wells, J. C., Coward, W. A., Cole, T. J., & Davies, P. S. The contribution of fat and fat-free tissue to body mass index in contemporary children and the reference child. Int. J. Obes Relat. Metab. Disord. 26, 1323-1328 (2002
-
(2002)
Int. J. Obes Relat. Metab. Disord
, vol.26
, pp. 1323-1328
-
-
Wells, J.C.1
Coward, W.A.2
Cole, T.J.3
Davies, P.S.4
-
16
-
-
84925295920
-
Epidemiology: Obesity and cancer-The evidence is fattening up
-
Kaaks, R., & Kühn, T. Epidemiology: obesity and cancer-The evidence is fattening up. Nat. Rev. Endocrinol. 10, 644-645 (2014
-
(2014)
Nat. Rev. Endocrinol
, vol.10
, pp. 644-645
-
-
Kaaks, R.1
Kühn, T.2
-
17
-
-
84928417731
-
Adult weight gain and adiposity-related cancers: A dose-response meta-Analysis of prospective observational studies
-
Keum, N., et al. Adult weight gain and adiposity-related cancers: a dose-response meta-Analysis of prospective observational studies. J. Natl Cancer Inst. 107, http://dx.doi.org/10.1093/jnci/djv088 (2015
-
(2015)
J. Natl Cancer Inst
, vol.107
-
-
Keum, N.1
-
18
-
-
38949108241
-
Body-mass index and incidence of cancer: A systematic review and meta-Analysis of prospective observational studies
-
Renehan, A. G., Tyson, M., Egger, M., Heller, R. F., & Zwahlen, M. Body-mass index and incidence of cancer: a systematic review and meta-Analysis of prospective observational studies. Lancet 371, 569-578 (2008
-
(2008)
Lancet
, vol.371
, pp. 569-578
-
-
Renehan, A.G.1
Tyson, M.2
Egger, M.3
Heller, R.F.4
Zwahlen, M.5
-
20
-
-
85051049708
-
-
World Cancer Research Fund and the American Institute for Cancer Research. Continuous update project report
-
World Cancer Research Fund and the American Institute for Cancer Research. Continuous update project report. Food, nutrition, physical activity, and the prevention of breast cancer. http://wcrf.org/sites/default/files/Breast-Cancer-2010-Report.pdf (2015
-
(2015)
Food Nutrition, Physical Activity, and the Prevention of Breast Cancer
-
-
-
22
-
-
77958517507
-
A systematic review and meta-Analysis of the relationship between body size and testicular cancer
-
Lerro, C. C., McGlynn, K. A., & Cook, M. B. A systematic review and meta-Analysis of the relationship between body size and testicular cancer. Br. J. Cancer 103, 1467-1474 (2010
-
(2010)
Br. J. Cancer
, vol.103
, pp. 1467-1474
-
-
Lerro, C.C.1
McGlynn, K.A.2
Cook, M.B.3
-
23
-
-
84872842637
-
Obesity and incidence of lung cancer: A meta-Analysis
-
Yang, Y., et al. Obesity and incidence of lung cancer: a meta-Analysis. Int. J. Cancer 132, 1162-1169 (2013
-
(2013)
Int. J. Cancer
, vol.132
, pp. 1162-1169
-
-
Yang, Y.1
-
24
-
-
84959868156
-
Trajectory of body shape across the lifespan and cancer risk
-
Song M., et al. Trajectory of body shape across the lifespan and cancer risk. Int. J. Cancer http://dx.doi.org/10.1002/ijc.29981 2015
-
(2015)
Int. J. Cancer
-
-
Song, M.1
-
25
-
-
85010767334
-
Overweight, obesity, and postmenopausal invasive breast cancer risk: A secondary analysis of the women's health initiative randomized clinical trials
-
Neuhouser, M. L., et al. Overweight, obesity, and postmenopausal invasive breast cancer risk: a secondary analysis of the women's health initiative randomized clinical trials. JAMA Oncol. 1, 611-621 (2015
-
(2015)
JAMA Oncol
, vol.1
, pp. 611-621
-
-
Neuhouser, M.L.1
-
26
-
-
37049013701
-
Cancer incidence and mortality in relation to body mass index in the Million Women Study: Cohort study
-
Reeves, G. K., et al. Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study. BMJ 335, 1134 (2007
-
(2007)
BMJ
, vol.335
, pp. 1134
-
-
Reeves, G.K.1
-
27
-
-
34548075820
-
Long-Term mortality after gastric bypass surgery
-
Adams, T. D., et al. Long-Term mortality after gastric bypass surgery. N. Engl. J. Med. 357, 753-761 (2007
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 753-761
-
-
Adams, T.D.1
-
28
-
-
67649344115
-
Effects of bariatric surgery on cancer incidence in obese patients in Sweden (swedish obese subjects study): A prospective, controlled intervention trial
-
Sjostrom, L., et al. Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial. Lancet Oncol. 10, 653-662 (2009
-
(2009)
Lancet Oncol
, vol.10
, pp. 653-662
-
-
Sjostrom, L.1
-
29
-
-
84953790264
-
Bariatric surgery in the United Kingdom: A cohort study of weight loss and clinical outcomes in routine clinical care
-
Douglas, I. J., Bhaskaran, K., Batterham, R. L., & Smeeth, L. Bariatric surgery in the United Kingdom: a cohort study of weight loss and clinical outcomes in routine clinical care. PLoS Med. 12, e1001925 (2015
-
(2015)
PLoS Med
, vol.12
, pp. e1001925
-
-
Douglas, I.J.1
Bhaskaran, K.2
Batterham, R.L.3
Smeeth, L.4
-
30
-
-
33745898835
-
Adult weight change and risk of postmenopausal breast cancer
-
Eliassen, A. H., Colditz, G. A., Rosner, B., Willett, W. C., & Hankinson, S. E. Adult weight change and risk of postmenopausal breast cancer. JAMA 296, 193-201 (2006
-
(2006)
JAMA
, vol.296
, pp. 193-201
-
-
Eliassen, A.H.1
Colditz, G.A.2
Rosner, B.3
Willett, W.C.4
Hankinson, S.E.5
-
31
-
-
0348141028
-
Intentional weight loss and incidence of obesity-related cancers: The Iowa Women's Health Study
-
Parker, E. D., & Folsom, A. R. Intentional weight loss and incidence of obesity-related cancers: the Iowa Women's Health Study. Int. J. Obes Relat. Metab. Disord. 27, 1447-1452 (2003
-
(2003)
Int. J. Obes Relat. Metab. Disord
, vol.27
, pp. 1447-1452
-
-
Parker, E.D.1
Folsom, A.R.2
-
32
-
-
84920768348
-
Type 2 diabetes and cancer: Umbrella review of meta-Analyses of observational studies
-
Tsilidis, K. K., Kasimis, J. C., Lopez, D. S., Ntzani, E. E., & Ioannidis, J. P. Type 2 diabetes and cancer: umbrella review of meta-Analyses of observational studies. BMJ 350, g7607 (2015
-
(2015)
BMJ
, vol.350
, pp. g7607
-
-
Tsilidis, K.K.1
Kasimis, J.C.2
Lopez, D.S.3
Ntzani, E.E.4
Ioannidis, J.P.5
-
33
-
-
84862215222
-
Cancer occurrence in Danish diabetic patients: Duration and insulin effects
-
Carstensen, B., Witte, D. R., & Friis, S. Cancer occurrence in Danish diabetic patients: duration and insulin effects. Diabetologia 55, 948-958 (2012
-
(2012)
Diabetologia
, vol.55
, pp. 948-958
-
-
Carstensen, B.1
Witte, D.R.2
Friis, S.3
-
34
-
-
84881593676
-
Cancer detection rates following enrolment in a disease management programme for type 2 diabetes
-
Geier, A. S., et al. Cancer detection rates following enrolment in a disease management programme for type 2 diabetes. Diabetologia 56, 1944-1948 (2013
-
(2013)
Diabetologia
, vol.56
, pp. 1944-1948
-
-
Geier, A.S.1
-
35
-
-
84882454326
-
Type 2 diabetes and risk of prostate cancer: A meta-Analysis of observational studies
-
Bansal, D., Bhansali, A., Kapil, G., Undela, K., & Tiwari, P. Type 2 diabetes and risk of prostate cancer: a meta-Analysis of observational studies. Prostate Cancer Prostat. Dis. 16, 151-158 (2013
-
(2013)
Prostate Cancer Prostat. Dis
, vol.16
, pp. 151-158
-
-
Bansal, D.1
Bhansali, A.2
Kapil, G.3
Undela, K.4
Tiwari, P.5
-
36
-
-
79956098758
-
Diabetes and risk of prostate cancer: A study using the national health insurance
-
Tseng, C. H. Diabetes and risk of prostate cancer: a study using the National Health Insurance. Diabetes Care 34, 616-621 (2011
-
(2011)
Diabetes Care
, vol.34
, pp. 616-621
-
-
Tseng, C.H.1
-
37
-
-
8744228132
-
Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes
-
Dhindsa, S., et al. Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes. J. Clin. Endocrinol. Metab. 89, 5462-5468 (2004
-
(2004)
J. Clin. Endocrinol. Metab
, vol.89
, pp. 5462-5468
-
-
Dhindsa, S.1
-
38
-
-
15244354259
-
Obesity and prostate cancer
-
Freedland, S. J., & Aronson, W. J. Obesity and prostate cancer. Urology 65, 433-439 (2005
-
(2005)
Urology
, vol.65
, pp. 433-439
-
-
Freedland, S.J.1
Aronson, W.J.2
-
39
-
-
54349083481
-
Prediagnostic body-mass index, plasma C peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: A long-Term survival analysis
-
Ma, J., et al. Prediagnostic body-mass index, plasma C peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-Term survival analysis. Lancet Oncol. 9, 1039-1047 (2008
-
(2008)
Lancet Oncol
, vol.9
, pp. 1039-1047
-
-
Ma, J.1
-
40
-
-
84907296915
-
Metformin and cancer risk and mortality: A systematic review and meta-Analysis taking into account biases and confounders
-
Gandini, S., et al. Metformin and cancer risk and mortality: a systematic review and meta-Analysis taking into account biases and confounders. Cancer Prev. Res. (Phila.) 7, 867-885 (2014
-
(2014)
Cancer Prev. Res. (Phila
, vol.7
, pp. 867-885
-
-
Gandini, S.1
-
41
-
-
84935873481
-
Pharmacologic therapy of diabetes and overall cancer risk and mortality: A meta-Analysis of 265 studies
-
Wu, L., Zhu, J., Prokop, L. J., & Murad, M. H. Pharmacologic therapy of diabetes and overall cancer risk and mortality: a meta-Analysis of 265 studies. Sci. Rep. 5, 10147 (2015
-
(2015)
Sci. Rep
, vol.5
, pp. 10147
-
-
Wu, L.1
Zhu, J.2
Prokop, L.J.3
Murad, M.H.4
-
42
-
-
20444461067
-
Metformin and reduced risk of cancer in diabetic patients
-
Evans, J. M., Donnelly, L. A., Emslie-Smith, A. M., Alessi, D. R., & Morris, A. D. Metformin and reduced risk of cancer in diabetic patients. BMJ 330, 1304-1305 (2005
-
(2005)
BMJ
, vol.330
, pp. 1304-1305
-
-
Evans, J.M.1
Donnelly, L.A.2
Emslie-Smith, A.M.3
Alessi, D.R.4
Morris, A.D.5
-
43
-
-
68449094354
-
Use of insulin glargine and cancer incidence in Scotland: A study from the scottish diabetes research network epidemiology group
-
Colhoun, H. M., & Group, S. E. Use of insulin glargine and cancer incidence in Scotland: a study from the Scottish Diabetes Research Network Epidemiology Group. Diabetologia 52, 1755-1765 (2009
-
(2009)
Diabetologia
, vol.52
, pp. 1755-1765
-
-
Colhoun, H.M.1
-
44
-
-
84939431907
-
Treatment with insulin (analogues) and breast cancer risk in diabetics; A systematic review and meta-Analysis of in vitro, animal and human evidence
-
Bronsveld, H. K., et al. Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-Analysis of in vitro, animal and human evidence. Breast Cancer Res. 17, 100 (2015
-
(2015)
Breast Cancer Res
, vol.17
, pp. 100
-
-
Bronsveld, H.K.1
-
45
-
-
84938983934
-
No reduced risk of overall, colorectal, lung, breast, and prostate cancer with metformin therapy in diabetic patients: Database analyses from Germany and the UK
-
Kowall, B., Stang, A., Rathmann, W., & Kostev, K. No reduced risk of overall, colorectal, lung, breast, and prostate cancer with metformin therapy in diabetic patients: database analyses from Germany and the UK. Pharmacoepidemiol. Drug Saf. 24, 865-874 (2015
-
(2015)
Pharmacoepidemiol. Drug Saf
, vol.24
, pp. 865-874
-
-
Kowall, B.1
Stang, A.2
Rathmann, W.3
Kostev, K.4
-
46
-
-
84869788946
-
Metformin and the risk of cancer: Time-related biases in observational studies
-
Suissa, S., & Azoulay, L. Metformin and the risk of cancer: time-related biases in observational studies. Diabetes Care 35, 2665-2673 (2012
-
(2012)
Diabetes Care
, vol.35
, pp. 2665-2673
-
-
Suissa, S.1
Azoulay, L.2
-
47
-
-
68349148204
-
Insulin glargine and malignancy: An unwarranted alarm
-
Pocock, S. J., & Smeeth, L. Insulin glargine and malignancy: an unwarranted alarm. Lancet 374, 511-513 (2009
-
(2009)
Lancet
, vol.374
, pp. 511-513
-
-
Pocock, S.J.1
Smeeth, L.2
-
48
-
-
84982995031
-
AACE/ACE comprehensive diabetes management algorithm 2015
-
Garber, A. J., et al. AACE/ACE comprehensive diabetes management algorithm 2015. Endocr. Pract. 21, 438-447 (2015
-
(2015)
Endocr. Pract
, vol.21
, pp. 438-447
-
-
Garber, A.J.1
-
49
-
-
84902110574
-
Overcoming drug development bottlenecks with repurposing: Repurposing biguanides to target energy metabolism for cancer treatment
-
Pollak, M. Overcoming drug development bottlenecks with repurposing: repurposing biguanides to target energy metabolism for cancer treatment. Nat. Med. 20, 591-593 (2014
-
(2014)
Nat. Med
, vol.20
, pp. 591-593
-
-
Pollak, M.1
-
50
-
-
84866322945
-
Investigating metformin for cancer prevention and treatment: The end of the beginning
-
Pollak, M. N. Investigating metformin for cancer prevention and treatment: the end of the beginning. Cancer Discov. 2, 778-790 (2012
-
(2012)
Cancer Discov
, vol.2
, pp. 778-790
-
-
Pollak, M.N.1
-
51
-
-
78649302320
-
Metformin and cancer risk in diabetic patients: A systematic review and meta-Analysis
-
Decensi, A., et al. Metformin and cancer risk in diabetic patients: a systematic review and meta-Analysis. Cancer Prev. Res. (Phila.) 3, 1451-1461 (2010
-
(2010)
Cancer Prev. Res. (Phila
, vol.3
, pp. 1451-1461
-
-
Decensi, A.1
-
52
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
Libby, G., et al. New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care 32, 1620-1625 (2009
-
(2009)
Diabetes Care
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
-
53
-
-
84858695046
-
Cancer risk in diabetic patients treated with metformin: A systematic review and meta-Analysis
-
Noto, H., Goto, A., Tsujimoto, T., & Noda, M. Cancer risk in diabetic patients treated with metformin: a systematic review and meta-Analysis. PLoS ONE 7, e33411 (2012
-
(2012)
PLoS ONE
, vol.7
, pp. e33411
-
-
Noto, H.1
Goto, A.2
Tsujimoto, T.3
Noda, M.4
-
54
-
-
84903549117
-
Incidence of bladder cancer in patients with type 2 diabetes treated with metformin or sulfonylureas
-
Mamtani, R., et al. Incidence of bladder cancer in patients with type 2 diabetes treated with metformin or sulfonylureas. Diabetes Care 37, 1910-1917 (2014
-
(2014)
Diabetes Care
, vol.37
, pp. 1910-1917
-
-
Mamtani, R.1
-
55
-
-
84906691535
-
Metformin does not affect cancer risk: A cohort study in the UK Clinical Practice Research Datalink analyzed like an intention-To treat trial
-
Tsilidis, K. K., et al. Metformin does not affect cancer risk: a cohort study in the UK Clinical Practice Research Datalink analyzed like an intention-To treat trial. Diabetes Care 37, 2522-2532 (2014
-
(2014)
Diabetes Care
, vol.37
, pp. 2522-2532
-
-
Tsilidis, K.K.1
-
56
-
-
84959298298
-
Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: A multicentre double-blind, placebo-controlled, randomised phase 3 trial
-
Higurashi T., et al. Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: a multicentre double-blind, placebo-controlled, randomised phase 3 trial. Lancet Oncol. http://dx.doi.org/10.1016/s1470-2045(15)00565-3 2016
-
(2016)
Lancet Oncol
-
-
Higurashi, T.1
-
57
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
Currie, C. J., Poole, C. D., & Gale, E. A. The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia 52, 1766-1777 (2009
-
(2009)
Diabetologia
, vol.52
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, C.D.2
Gale, E.A.3
-
58
-
-
68449104156
-
Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: A cohort study
-
Hemkens, L. G., et al. Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study. Diabetologia 52, 1732-1744 (2009
-
(2009)
Diabetologia
, vol.52
, pp. 1732-1744
-
-
Hemkens, L.G.1
-
59
-
-
68449104625
-
Insulin glargine use and short-Term incidence of malignancies a population-based follow up study in Sweden
-
Jonasson, J. M., et al. Insulin glargine use and short-Term incidence of malignancies a population-based follow up study in Sweden. Diabetologia 52, 1745-1754 (2009
-
(2009)
Diabetologia
, vol.52
, pp. 1745-1754
-
-
Jonasson, J.M.1
-
60
-
-
47349085657
-
Proliferative effects of insulin analogues on mammary epithelial cells
-
Mayer, D., Shukla, A., & Enzmann, H. Proliferative effects of insulin analogues on mammary epithelial cells. Arch. Physiol. Biochem. 114, 38-44 (2008
-
(2008)
Arch. Physiol. Biochem
, vol.114
, pp. 38-44
-
-
Mayer, D.1
Shukla, A.2
Enzmann, H.3
-
61
-
-
84962097583
-
The effect of long-Acting insulin analogs on the risk of cancer: A systematic review of observational studies
-
Wu J. W., Filion, K. B., Azoulay, L., Doll, M. K., & Suissa, S. The effect of long-Acting insulin analogs on the risk of cancer: a systematic review of observational studies. Diabetes Care http://dx.doi.org/10.2337/dc15-1816 2016
-
(2016)
Diabetes Care
-
-
Wu, J.W.1
Filion, K.B.2
Azoulay, L.3
Doll, M.K.4
Suissa, S.5
-
62
-
-
0036894342
-
Sulfonylurea stimulation of insulin secretion
-
Proks, P., Reimann, F., Green, N., Gribble, F., & Ashcroft, F. Sulfonylurea stimulation of insulin secretion. Diabetes 51 (Suppl. 3), S368-S376 (2002
-
(2002)
Diabetes
, vol.51
, pp. S368-S376
-
-
Proks, P.1
Reimann, F.2
Green, N.3
Gribble, F.4
Ashcroft, F.5
-
63
-
-
84857640868
-
The insulin and insulin-like growth factor receptor family in neoplasia: An update
-
Pollak, M. The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nat. Rev. Cancer 12, 159-169 (2012
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 159-169
-
-
Pollak, M.1
-
64
-
-
84863566117
-
Oral insulin secretagogues, insulin, and cancer risk in type 2 diabetes mellitus
-
Chang, C. H., Lin, J. W., Wu, L. C., Lai, M. S., & Chuang, L. M. Oral insulin secretagogues, insulin, and cancer risk in type 2 diabetes mellitus. J. Clin. Endocrinol. Metab. 97, E1170-1175 (2012
-
(2012)
J. Clin. Endocrinol. Metab
, vol.97
, pp. E1170-1175
-
-
Chang, C.H.1
Lin, J.W.2
Wu, L.C.3
Lai, M.S.4
Chuang, L.M.5
-
65
-
-
84919980137
-
Are sulfonylurea and insulin therapies associated with a larger risk of cancer than metformin therapy? A retrospective database analysis
-
Kowall, B., Rathmann, W., & Kostev, K. Are sulfonylurea and insulin therapies associated with a larger risk of cancer than metformin therapy? A retrospective database analysis. Diabetes Care 38, 59-65 (2015
-
(2015)
Diabetes Care
, vol.38
, pp. 59-65
-
-
Kowall, B.1
Rathmann, W.2
Kostev, K.3
-
66
-
-
84962374171
-
The use of glyburide compared with other sulfonylureas and the risk of cancer in patients with type 2 diabetes
-
Tuccori, M., Wu, J. W., Yin, H., Majdan, A., & Azoulay, L. The use of glyburide compared with other sulfonylureas and the risk of cancer in patients with type 2 diabetes. Diabetes Care 38, 2083-2089 (2015
-
(2015)
Diabetes Care
, vol.38
, pp. 2083-2089
-
-
Tuccori, M.1
Wu, J.W.2
Yin, H.3
Majdan, A.4
Azoulay, L.5
-
67
-
-
84949627846
-
Bladder cancer: Pioglitazone-when is a prescription drug safe?
-
Loke, Y. K., & Mattishent, K. Bladder cancer: pioglitazone-when is a prescription drug safe? Nat. Rev. Urol. 12, 655-656 (2015
-
(2015)
Nat. Rev. Urol
, vol.12
, pp. 655-656
-
-
Loke, Y.K.1
Mattishent, K.2
-
68
-
-
26244453309
-
Secondary prevention of macrovascular events in patients with type 2 diabetes in the proactive study (prospective pioglitazone clinical trial in macrovascular events): A randomised controlled trial
-
Dormandy, J. A., et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 366, 1279-1289 (2005
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
-
69
-
-
79956217900
-
Risk of bladder cancer among diabetic patients treated with pioglitazone: Interim report of a longitudinal cohort study
-
Lewis, J. D., et al. Risk of bladder cancer among diabetic patients treated with pioglitazone: interim report of a longitudinal cohort study. Diabetes Care 34, 916-922 (2011
-
(2011)
Diabetes Care
, vol.34
, pp. 916-922
-
-
Lewis, J.D.1
-
70
-
-
84862684037
-
The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: Nested case-control study
-
Azoulay, L., et al. The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study. BMJ 344, e3645 (2012
-
(2012)
BMJ
, vol.344
, pp. e3645
-
-
Azoulay, L.1
-
72
-
-
84924662049
-
Pioglitazone and bladder cancer risk: A multipopulation pooled cumulative exposure analysis
-
Levin, D., et al. Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis. Diabetologia 58, 493-504 (2015
-
(2015)
Diabetologia
, vol.58
, pp. 493-504
-
-
Levin, D.1
-
73
-
-
84938364689
-
Pioglitazone use and risk of bladder cancer and other common cancers in persons with diabetes
-
Lewis, J. D., et al. Pioglitazone use and risk of bladder cancer and other common cancers in persons with diabetes. JAMA 314, 265-277 (2015
-
(2015)
JAMA
, vol.314
, pp. 265-277
-
-
Lewis, J.D.1
-
74
-
-
84955608255
-
Examples of how the pharmaceutical industries distort the evidence of drug safety: The case of pioglitazone and the bladder cancer issue
-
Faillie J. L., & Hillaire-Buys, D. Examples of how the pharmaceutical industries distort the evidence of drug safety: the case of pioglitazone and the bladder cancer issue. Pharmacoepidemiol. Drug Saf. http://dx.doi.org/10.1002/pds.3925 2015
-
(2015)
Pharmacoepidemiol. Drug Saf
-
-
Faillie, J.L.1
Hillaire-Buys, D.2
-
75
-
-
84962052919
-
Pioglitazone use and risk of bladder cancer: Population based cohort study
-
Tuccori, M., et al. Pioglitazone use and risk of bladder cancer: population based cohort study. BMJ 352, i1541 (2016
-
(2016)
BMJ
, vol.352
, pp. i1541
-
-
Tuccori, M.1
-
76
-
-
79959559653
-
Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide 1 based therapies
-
Elashoff, M., Matveyenko, A. V., Gier, B., Elashoff, R., & Butler, P. C. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide 1 based therapies. Gastroenterology 141, 150-156 (2011
-
(2011)
Gastroenterology
, vol.141
, pp. 150-156
-
-
Elashoff, M.1
Matveyenko, A.V.2
Gier, B.3
Elashoff, R.4
Butler, P.C.5
-
77
-
-
84884903039
-
The association of pancreatitis with antidiabetic drug use: Gaining insight through the FDA pharmacovigilance database
-
Raschi, E., Piccinni, C., Poluzzi, E., Marchesini, G., & De Ponti, F. The association of pancreatitis with antidiabetic drug use: gaining insight through the FDA pharmacovigilance database. Acta Diabetol. 50, 569-577 (2013
-
(2013)
Acta Diabetol
, vol.50
, pp. 569-577
-
-
Raschi, E.1
Piccinni, C.2
Poluzzi, E.3
Marchesini, G.4
De Ponti, F.5
-
78
-
-
84946035690
-
Incretin-based drugs and adverse pancreatic events: Almost a decade later and uncertainty remains
-
Azoulay, L. Incretin-based drugs and adverse pancreatic events: almost a decade later and uncertainty remains. Diabetes Care 38, 951-953 (2015
-
(2015)
Diabetes Care
, vol.38
, pp. 951-953
-
-
Azoulay, L.1
-
79
-
-
84920391308
-
Dipeptidyl-peptidase 4 inhibitors and pancreatic cancer: A cohort study
-
Gokhale, M., et al. Dipeptidyl-peptidase 4 inhibitors and pancreatic cancer: a cohort study. Diabetes, Obes. Metabolism 16, 1247-1256 (2014
-
(2014)
Diabetes, Obes. Metabolism
, vol.16
, pp. 1247-1256
-
-
Gokhale, M.1
-
80
-
-
84955214680
-
Sitagliptin and pancreatic cancer risk in patients with type 2 diabetes
-
Tseng, C. H. Sitagliptin and pancreatic cancer risk in patients with type 2 diabetes. Eur. J. Clin. Invest. 46, 70-79 (2016
-
(2016)
Eur. J. Clin. Invest
, vol.46
, pp. 70-79
-
-
Tseng, C.H.1
-
81
-
-
84937053742
-
Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes
-
Green, J. B., et al. Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. N. Engl. J. Med. 373, 232-242 (2015
-
(2015)
N. Engl. J. Med
, vol.373
, pp. 232-242
-
-
Green, J.B.1
-
82
-
-
84896731936
-
Pancreatic safety of incretin-based drugs-FDA and EMA assessment
-
Egan, A. G., et al. Pancreatic safety of incretin-based drugs-FDA and EMA assessment. N. Engl. J. Med. 370, 794-797 (2014
-
(2014)
N. Engl. J. Med
, vol.370
, pp. 794-797
-
-
Egan, A.G.1
-
83
-
-
83655191987
-
Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: Relevance for incretin-based diabetes therapy
-
Waser, B., Beetschen, K., Pellegata, N. S., & Reubi, J. C. Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: relevance for incretin-based diabetes therapy. Neuroendocrinology 94, 291-301 (2011
-
(2011)
Neuroendocrinology
, vol.94
, pp. 291-301
-
-
Waser, B.1
Beetschen, K.2
Pellegata, N.S.3
Reubi, J.C.4
-
84
-
-
84875702681
-
On target effects of GLP 1 receptor agonists on thyroid C cells in rats and mice
-
Rosol, T. J. On target effects of GLP 1 receptor agonists on thyroid C cells in rats and mice. Toxicol. Pathol. 41, 303-309 (2013
-
(2013)
Toxicol. Pathol
, vol.41
, pp. 303-309
-
-
Rosol, T.J.1
-
85
-
-
84995600615
-
Glucagon-like peptide 1 receptor agonists for type 2 diabetes: A clinical update of safety and efficacy
-
Drab S. R. Glucagon-like peptide 1 receptor agonists for type 2 diabetes: a clinical update of safety and efficacy. Curr. Diabetes Rev. http://dx.doi.org/10.2174/1573399812666151223093841 2015
-
(2015)
Curr. Diabetes Rev
-
-
Drab, S.R.1
-
86
-
-
84924428027
-
GLP 1R agonists promote normal and neoplastic intestinal growth through mechanisms requiring Fgf7
-
Koehler, J. A., et al. GLP 1R agonists promote normal and neoplastic intestinal growth through mechanisms requiring Fgf7. Cell. Metab. 21, 379-391 (2015
-
(2015)
Cell. Metab
, vol.21
, pp. 379-391
-
-
Koehler, J.A.1
-
87
-
-
84908245468
-
Cancer cachexia: Understanding the molecular basis
-
Argiles, J. M., Busquets, S., Stemmler, B., & Lopez-Soriano, F. J. Cancer cachexia: understanding the molecular basis. Nat. Rev. Cancer 14, 754-762 (2014
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 754-762
-
-
Argiles, J.M.1
Busquets, S.2
Stemmler, B.3
Lopez-Soriano, F.J.4
-
88
-
-
0037464510
-
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults
-
Calle, E. E., Rodriguez, C., Walker-Thurmond, K., & Thun, M. J. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults. N. Engl. J. Med. 348, 1625-1638 (2003
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 1625-1638
-
-
Calle, E.E.1
Rodriguez, C.2
Walker-Thurmond, K.3
Thun, M.J.4
-
89
-
-
0027446902
-
Utility of the National Death Index for ascertainment of mortality among cancer prevention study II participants
-
Calle, E. E., & Terrell, D. D. Utility of the National Death Index for ascertainment of mortality among cancer prevention study II participants. Am. J. Epidemiol. 137, 235-241 (1993
-
(1993)
Am. J. Epidemiol
, vol.137
, pp. 235-241
-
-
Calle, E.E.1
Terrell, D.D.2
-
90
-
-
84907597890
-
Body mass index and survival in women with breast cancer-systematic literature review and meta-Analysis of 82 follow up studies
-
Chan, D. S., et al. Body mass index and survival in women with breast cancer-systematic literature review and meta-Analysis of 82 follow up studies. Ann. Oncol. 25, 1901-1914 (2014
-
(2014)
Ann. Oncol
, vol.25
, pp. 1901-1914
-
-
Chan, D.S.1
-
91
-
-
84922546987
-
Obesity and the outcome of young breast cancer patients in the UK: The POSH study
-
Copson, E. R., et al. Obesity and the outcome of young breast cancer patients in the UK: the POSH study. Ann. Oncol. 26, 101-112 (2015
-
(2015)
Ann. Oncol
, vol.26
, pp. 101-112
-
-
Copson, E.R.1
-
92
-
-
84964912488
-
Weight gain after breast cancer diagnosis and all-cause mortality: Systematic review and meta-Analysis
-
Playdon, M. C., et al. weight gain after breast cancer diagnosis and all-cause mortality: systematic review and meta-Analysis. J. Natl Cancer Inst. 107, djv275 (2015
-
(2015)
J. Natl Cancer Inst
, vol.107
, pp. djv275
-
-
Playdon, M.C.1
-
93
-
-
84891437243
-
Modification of the association between obesity and lethal prostate cancer by TMPRSS2:ERG
-
Pettersson, A., et al. Modification of the association between obesity and lethal prostate cancer by TMPRSS2:ERG. J. Natl Cancer Inst. 105, 1881-1890 (2013
-
(2013)
J. Natl Cancer Inst
, vol.105
, pp. 1881-1890
-
-
Pettersson, A.1
-
94
-
-
84905861171
-
Randomized trial of a telephone-based weight loss intervention in postmenopausal women with breast cancer receiving letrozole: The LISA trial
-
Goodwin, P. J., et al. Randomized trial of a telephone-based weight loss intervention in postmenopausal women with breast cancer receiving letrozole: the LISA trial. J. Clin. Oncol. 32, 2231-2239 (2014
-
(2014)
J. Clin. Oncol
, vol.32
, pp. 2231-2239
-
-
Goodwin, P.J.1
-
95
-
-
84969930805
-
Obesity-Associated alterations in inflammation, epigenetics, and mammary tumor growth persist in formerly obese mice
-
Rossi, E. L., et al. Obesity-Associated alterations in inflammation, epigenetics, and mammary tumor growth persist in formerly obese mice. Cancer Prev. Res. (Phila.) 9, 339-348 (2016
-
(2016)
Cancer Prev. Res. (Phila
, vol.9
, pp. 339-348
-
-
Rossi, E.L.1
-
96
-
-
84958890227
-
The influence of obesity on survival in early, high-risk breast cancer: Results from the randomized SUCCESS A trial
-
Widschwendter, P., et al. The influence of obesity on survival in early, high-risk breast cancer: results from the randomized SUCCESS A trial. Breast Cancer Res. 17, 129 (2015
-
(2015)
Breast Cancer Res
, vol.17
, pp. 129
-
-
Widschwendter, P.1
-
97
-
-
84943362588
-
Obesity and survival among women with ovarian cancer: Results from the ovarian cancer association consortium
-
Nagle, C. M., et al. Obesity and survival among women with ovarian cancer: results from the Ovarian Cancer Association Consortium. Br. J. Cancer 113, 817-826 (2015
-
(2015)
Br. J. Cancer
, vol.113
, pp. 817-826
-
-
Nagle, C.M.1
-
98
-
-
84891444793
-
An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma
-
Hakimi, A. A., et al. An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma. J. Natl Cancer Inst. 105, 1862-1870 (2013
-
(2013)
J. Natl Cancer Inst
, vol.105
, pp. 1862-1870
-
-
Hakimi, A.A.1
-
99
-
-
84897551029
-
Obesity and cardiovascular diseases: Implications regarding fitness, fatness, and severity in the obesity paradox
-
Lavie, C. J., McAuley, P. A., Church, T. S., Milani, R. V., & Blair, S. N. Obesity and cardiovascular diseases: implications regarding fitness, fatness, and severity in the obesity paradox. J. Am. College Cardiol. 63, 1345-1354 (2014
-
(2014)
J. Am. College Cardiol
, vol.63
, pp. 1345-1354
-
-
Lavie, C.J.1
McAuley, P.A.2
Church, T.S.3
Milani, R.V.4
Blair, S.N.5
-
100
-
-
84871382568
-
Obesity paradox: Differential effects on cancer and noncancer mortality in patients with type 2 diabetes mellitus
-
Tseng, C. H. Obesity paradox: differential effects on cancer and noncancer mortality in patients with type 2 diabetes mellitus. Atherosclerosis 226, 186-192 (2013
-
(2013)
Atherosclerosis
, vol.226
, pp. 186-192
-
-
Tseng, C.H.1
-
101
-
-
79952260576
-
Diabetes mellitus, fasting glucose, and risk of cause-specific death
-
Seshasai, S. R., et al. Diabetes mellitus, fasting glucose, and risk of cause-specific death. N. Engl. J. Med. 364, 829-841 (2011
-
(2011)
N. Engl. J. Med
, vol.364
, pp. 829-841
-
-
Seshasai, S.R.1
-
102
-
-
77954405226
-
Colorectal cancer outcomes, recurrence, and complications in persons with and without diabetes mellitus: A systematic review and meta-Analysis
-
Stein, K. B., et al. Colorectal cancer outcomes, recurrence, and complications in persons with and without diabetes mellitus: a systematic review and meta-Analysis. Dig. Dis. Sci. 55, 1839-1851 (2010
-
(2010)
Dig. Dis. Sci
, vol.55
, pp. 1839-1851
-
-
Stein, K.B.1
-
103
-
-
76949099436
-
Does pre-existing diabetes affect prostate cancer prognosis? A systematic review
-
Snyder, C. F., et al. Does pre-existing diabetes affect prostate cancer prognosis? A systematic review. Prostate Cancer Prostat. Dis. 13, 58-64 (2010
-
(2010)
Prostate Cancer Prostat. Dis
, vol.13
, pp. 58-64
-
-
Snyder, C.F.1
-
104
-
-
84895539904
-
Type 2 diabetes and the risk of mortality among patients with prostate cancer
-
Bensimon, L., Yin, H., Suissa, S., Pollak, M. N., & Azoulay, L. Type 2 diabetes and the risk of mortality among patients with prostate cancer. Cancer Causes Control 25, 329-338 (2014
-
(2014)
Cancer Causes Control
, vol.25
, pp. 329-338
-
-
Bensimon, L.1
Yin, H.2
Suissa, S.3
Pollak, M.N.4
Azoulay, L.5
-
105
-
-
84924421740
-
Prostate cancer, prostate cancer death, and death from other causes, among men with metabolic aberrations
-
Haggstrom, C., et al. Prostate cancer, prostate cancer death, and death from other causes, among men with metabolic aberrations. Epidemiology 25, 823-828 (2014
-
(2014)
Epidemiology
, vol.25
, pp. 823-828
-
-
Haggstrom, C.1
-
106
-
-
79951960884
-
Diabetes mellitus and breast cancer outcomes: A systematic review and meta-Analysis
-
Peairs, K. S., et al. Diabetes mellitus and breast cancer outcomes: a systematic review and meta-Analysis. J. Clin. Oncol. 29, 40-46 (2011
-
(2011)
J. Clin. Oncol
, vol.29
, pp. 40-46
-
-
Peairs, K.S.1
-
107
-
-
84940795985
-
Pre-existing diabetes and breast cancer prognosis among elderly women
-
Luo, J., et al. Pre-existing diabetes and breast cancer prognosis among elderly women. Br. J. Cancer 113, 827-832 (2015
-
(2015)
Br. J. Cancer
, vol.113
, pp. 827-832
-
-
Luo, J.1
-
108
-
-
84922749733
-
Diabetes and other comorbidities in breast cancer survival by race/ethnicity: The California breast cancer survivorship consortium (cbcsc
-
Wu, A. H., et al. Diabetes and other comorbidities in breast cancer survival by race/ethnicity: the California Breast Cancer Survivorship Consortium (CBCSC). Cancer Epidemiol. Biomarkers Prev. 24, 361-368 (2015
-
(2015)
Cancer Epidemiol. Biomarkers Prev
, vol.24
, pp. 361-368
-
-
Wu, A.H.1
-
109
-
-
0033143455
-
A comprehensive prognostic index to predict survival based on multiple comorbidities: A focus on breast cancer
-
Fleming, S. T., Rastogi, A., Dmitrienko, A., & Johnson, K. D. A comprehensive prognostic index to predict survival based on multiple comorbidities: a focus on breast cancer. Med. Care 37, 601-614 (1999
-
(1999)
Med. Care
, vol.37
, pp. 601-614
-
-
Fleming, S.T.1
Rastogi, A.2
Dmitrienko, A.3
Johnson, K.D.4
-
110
-
-
65549157490
-
Impact of diabetes mellitus on complications and outcomes of adjuvant chemotherapy in older patients with breast cancer
-
Srokowski, T. P., Fang, S., Hortobagyi, G. N., & Giordano, S. H. Impact of diabetes mellitus on complications and outcomes of adjuvant chemotherapy in older patients with breast cancer. J. Clin. Oncol. 27, 2170-2176 (2009
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 2170-2176
-
-
Srokowski, T.P.1
Fang, S.2
Hortobagyi, G.N.3
Giordano, S.H.4
-
111
-
-
84886557970
-
Metformin use and all-cause and prostate cancer-specific mortality among men with diabetes
-
Margel, D., et al. Metformin use and all-cause and prostate cancer-specific mortality among men with diabetes. J. Clin. Oncol. 31, 3069-3075 (2013
-
(2013)
J. Clin. Oncol
, vol.31
, pp. 3069-3075
-
-
Margel, D.1
-
112
-
-
84907486203
-
The use of metformin in patients with prostate cancer and the risk of death
-
Bensimon, L., Yin, H., Suissa, S., Pollak, M. N., & Azoulay, L. The use of metformin in patients with prostate cancer and the risk of death. Cancer Epidemiol. Biomarkers Prev. 23, 2111-2118 (2014
-
(2014)
Cancer Epidemiol. Biomarkers Prev
, vol.23
, pp. 2111-2118
-
-
Bensimon, L.1
Yin, H.2
Suissa, S.3
Pollak, M.N.4
Azoulay, L.5
-
113
-
-
84953356462
-
Metformin and prostate cancer mortality: A meta-Analysis
-
Stopsack, K. H., Ziehr, D. R., Rider, J. R., & Giovannucci, E. L. Metformin and prostate cancer mortality: a meta-Analysis. Cancer Causes Control http://dx.doi.org/10.1007/s10552-015-0687-0 (2015
-
(2015)
Cancer Causes Control
-
-
Stopsack, K.H.1
Ziehr, D.R.2
Rider, J.R.3
Giovannucci, E.L.4
-
114
-
-
84904398047
-
The prognostic value of metformin for cancer patients with concurrent diabetes: A systematic review and meta-Analysis
-
Zhang Z. J., & Li, S. The prognostic value of metformin for cancer patients with concurrent diabetes: a systematic review and meta-Analysis. Diabetes Obes. Metab. 16, 707-710 (2014
-
(2014)
Diabetes Obes. Metab
, vol.16
, pp. 707-710
-
-
Zhang, Z.J.1
Li, S.2
-
115
-
-
84864314304
-
Metformin and thiazolidinediones are associated with improved breast cancer-specific survival of diabetic women with HER2+ breast cancer
-
He, X., et al. Metformin and thiazolidinediones are associated with improved breast cancer-specific survival of diabetic women with HER2+ breast cancer. Ann. Oncol. 23, 1771-1780 (2012
-
(2012)
Ann. Oncol
, vol.23
, pp. 1771-1780
-
-
He, X.1
-
116
-
-
84255169908
-
Relationship of type II diabetes and metformin use to ovarian cancer progression, survival, and chemosensitivity
-
Romero, I. L., et al. Relationship of type II diabetes and metformin use to ovarian cancer progression, survival, and chemosensitivity. Obstetr. Gynecol. 119, 61-67 (2012
-
(2012)
Obstetr. Gynecol
, vol.119
, pp. 61-67
-
-
Romero, I.L.1
-
117
-
-
84964330199
-
High sensitivity of an Ha RAS transgenic model of superficial bladder cancer to metformin is associated with approximately 240 fold higher drug concentration in urine than serum
-
Liu, Z., et al. High sensitivity of an Ha RAS transgenic model of superficial bladder cancer to metformin is associated with approximately 240 fold higher drug concentration in urine than serum. Mol. Cancer Ther. 15, 430-438 (2016
-
(2016)
Mol. Cancer Ther
, vol.15
, pp. 430-438
-
-
Liu, Z.1
-
118
-
-
84961588750
-
High efficacy of intravesical treatment of metformin on bladder cancer in preclinical model
-
Peng, M., et al. High efficacy of intravesical treatment of metformin on bladder cancer in preclinical model. Oncotarget http://dx.doi.org/10.18632/oncotarget.6933 (2016
-
(2016)
Oncotarget
-
-
Peng, M.1
-
119
-
-
84940467397
-
The effect of metformin on cancer-specific survival outcomes in diabetic patients undergoing radical cystectomy for urothelial carcinoma of the bladder
-
e387-e313
-
Nayan M., et al. The effect of metformin on cancer-specific survival outcomes in diabetic patients undergoing radical cystectomy for urothelial carcinoma of the bladder. Urol. Oncol. 33, 386. e387-e313 (2015
-
(2015)
Urol. Oncol
, vol.33
, pp. 386
-
-
Nayan, M.1
-
120
-
-
84973302297
-
-
ClinicalTrials.gov
-
US National Library of Medicine. ClinicalTrials.gov, https://clinicaltrials.gov/ct2/results?term=%22 cancer%22+AND+%22metformin%22+AND+ %22treating%22&Search=Search (2015
-
(2015)
US National Library of Medicine
-
-
-
121
-
-
84922005443
-
Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial
-
DeCensi A., et al. Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial. Breast Cancer Res. Treat. 148, 81-90 (2014
-
(2014)
Breast Cancer Res. Treat
, vol.148
, pp. 81-90
-
-
DeCensi, A.1
-
122
-
-
84932630141
-
Neoadjuvant window studies of metformin and biomarker development for drugs targeting cancer metabolism
-
Lord, S. R., et al. Neoadjuvant window studies of metformin and biomarker development for drugs targeting cancer metabolism. J. Natl Cancer Inst. Monogr. 2015, 81-86 (2015
-
(2015)
J. Natl Cancer Inst. Monogr
, vol.2015
, pp. 81-86
-
-
Lord, S.R.1
-
123
-
-
84925492210
-
Evidence for biological effects of metformin in operable breast cancer: Biomarker analysis in a pre-operative window of opportunity randomized trial
-
Hadad, S. M., et al. Evidence for biological effects of metformin in operable breast cancer: biomarker analysis in a pre-operative window of opportunity randomized trial. Breast Cancer Res. Treat. 150, 149-155 (2015
-
(2015)
Breast Cancer Res. Treat
, vol.150
, pp. 149-155
-
-
Hadad, S.M.1
-
124
-
-
84937512689
-
Metformin in patients with advanced pancreatic cancer: A double-blind, randomised, placebo-controlled phase 2 trial
-
Kordes, S., et al. Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial. Lancet Oncol. 16, 839-847 (2015
-
(2015)
Lancet Oncol
, vol.16
, pp. 839-847
-
-
Kordes, S.1
-
125
-
-
84962300475
-
Ir)relevance of metformin treatment in patients with metastatic pancreatic cancer: An open-label, randomized phase 2 trial
-
Reni, M., et al. (Ir)relevance of metformin treatment in patients with metastatic pancreatic cancer: an open-label, randomized phase 2 trial. Clin. Cancer Res. http://dx.doi.org/10.1158/1078-0432.ccr-15-1722 (2015
-
(2015)
Clin. Cancer Res
-
-
Reni, M.1
-
126
-
-
84930404106
-
Effect of metformin versus placebo on and metabolic factors in NCIC CTG MA.32
-
Goodwin, P. J., et al. Effect of metformin versus placebo on and metabolic factors in NCIC CTG MA.32. J. Natl Cancer Inst. 107, http://dx.doi.org/10.1093/jnci/djv006 (2015
-
(2015)
J. Natl Cancer Inst
, vol.107
-
-
Goodwin, P.J.1
-
127
-
-
0036138579
-
Fasting insulin and outcome in early-stage breast cancer: Results of a prospective cohort study
-
Goodwin, P. J., et al. Fasting insulin and outcome in early-stage breast cancer: results of a prospective cohort study. J. Clin. Oncol. 20, 42-51 (2002
-
(2002)
J. Clin. Oncol
, vol.20
, pp. 42-51
-
-
Goodwin, P.J.1
-
128
-
-
84925405909
-
The association between glucose-lowering drug use and mortality among breast cancer patients with type 2 diabetes
-
Vissers, P. A., et al. The association between glucose-lowering drug use and mortality among breast cancer patients with type 2 diabetes. Breast Cancer Res. Treatment 150, 427-437 (2015
-
(2015)
Breast Cancer Res. Treatment
, vol.150
, pp. 427-437
-
-
Vissers, P.A.1
-
129
-
-
84931434056
-
Obesity and diabetes: The increased risk of cancer and cancer-related mortality
-
Gallagher, E. J., & LeRoith, D. Obesity and diabetes: the increased risk of cancer and cancer-related mortality. Physiol. Rev. 95, 727-748 (2015
-
(2015)
Physiol. Rev
, vol.95
, pp. 727-748
-
-
Gallagher, E.J.1
LeRoith, D.2
-
130
-
-
65349167305
-
Do cancer cells care if their host is hungry?
-
Pollak, M. Do cancer cells care if their host is hungry? Cell. Metabolism 9, 401-403 (2009
-
(2009)
Cell. Metabolism
, vol.9
, pp. 401-403
-
-
Pollak, M.1
-
131
-
-
84948182161
-
Obesity and cancer: Mechanistic insights from transdisciplinary studies
-
Allott, E. H., & Hursting, S. D. Obesity and cancer: mechanistic insights from transdisciplinary studies. Endocr. Relat. Cancer 22, R365-R386 (2015
-
(2015)
Endocr. Relat. Cancer
, vol.22
, pp. R365-R386
-
-
Allott, E.H.1
Hursting, S.D.2
-
132
-
-
84921345437
-
Obesity and cancer: Local and systemic mechanisms
-
Iyengar, N. M., Hudis, C. A., & Dannenberg, A. J. Obesity and cancer: local and systemic mechanisms. Annu. Rev. Med. 66, 297-309 (2015
-
(2015)
Annu. Rev. Med
, vol.66
, pp. 297-309
-
-
Iyengar, N.M.1
Hudis, C.A.2
Dannenberg, A.J.3
-
133
-
-
84937842901
-
Adiposity and cancer risk: New mechanistic insights from epidemiology
-
Renehan, A. G., Zwahlen, M., & Egger, M. Adiposity and cancer risk: new mechanistic insights from epidemiology. Nat. Rev. Cancer 15, 484-498 (2015
-
(2015)
Nat. Rev. Cancer
, vol.15
, pp. 484-498
-
-
Renehan, A.G.1
Zwahlen, M.2
Egger, M.3
-
134
-
-
0344641797
-
The influence of the degree of caloric restriction on the formation of skin tumors and hepatomas in mice
-
Tannenbaum, A., & Silverstone, H. The influence of the degree of caloric restriction on the formation of skin tumors and hepatomas in mice. Cancer Res. 9, 724-727 (1949
-
(1949)
Cancer Res
, vol.9
, pp. 724-727
-
-
Tannenbaum, A.1
Silverstone, H.2
-
135
-
-
77953589054
-
Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase
-
Algire, C., Amrein, L., Zakikhani, M., Panasci, L., & Pollak, M. Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase. Endocr. Relat. Cancer 17, 351-360 (2010
-
(2010)
Endocr. Relat. Cancer
, vol.17
, pp. 351-360
-
-
Algire, C.1
Amrein, L.2
Zakikhani, M.3
Panasci, L.4
Pollak, M.5
-
136
-
-
84964777727
-
A nested case-control study of metabolically defined body size phenotypes and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC
-
Murphy, N., et al. A nested case-control study of metabolically defined body size phenotypes and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). PLoS. Med. 13, e1001988 (2016
-
(2016)
PLoS. Med
, vol.13
, pp. e1001988
-
-
Murphy, N.1
-
137
-
-
84880538920
-
Hyperglycaemia, insulin resistance, impaired pancreatic beta-cell function, and risk of pancreatic cancer
-
Wolpin, B. M., et al. Hyperglycaemia, insulin resistance, impaired pancreatic beta-cell function, and risk of pancreatic cancer. J. Natl Cancer Inst. 105, 1027-1035 (2013
-
(2013)
J. Natl Cancer Inst
, vol.105
, pp. 1027-1035
-
-
Wolpin, B.M.1
-
138
-
-
84866122452
-
PTEN mutations as a cause of constitutive insulin sensitivity and obesity
-
Pal, A., et al. PTEN mutations as a cause of constitutive insulin sensitivity and obesity. N. Engl. J. Med. 367, 1002-1011 (2012
-
(2012)
N. Engl. J. Med
, vol.367
, pp. 1002-1011
-
-
Pal, A.1
-
139
-
-
84928435995
-
Pharmacological inhibition of PI3K reduces adiposity and metabolic syndrome in obese mice and rhesus monkeys
-
Ortega-Molina, A., et al. Pharmacological inhibition of PI3K reduces adiposity and metabolic syndrome in obese mice and rhesus monkeys. Cell. Metabolism 21, 558-570 (2015
-
(2015)
Cell. Metabolism
, vol.21
, pp. 558-570
-
-
Ortega-Molina, A.1
-
140
-
-
70849120946
-
Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease
-
Belfiore, A., Frasca, F., Pandini, G., Sciacca, L., & Vigneri, R. Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease. Endocr. Rev. 30, 586-623 (2009
-
(2009)
Endocr. Rev
, vol.30
, pp. 586-623
-
-
Belfiore, A.1
Frasca, F.2
Pandini, G.3
Sciacca, L.4
Vigneri, R.5
-
141
-
-
0032559272
-
Plasma insulin-like growth factor i and prostate cancer risk: A prospective study
-
Chan, J. M., et al. Plasma insulin-like growth factor I and prostate cancer risk: a prospective study. Science 279, 563-566 (1998
-
(1998)
Science
, vol.279
, pp. 563-566
-
-
Chan, J.M.1
-
142
-
-
84969972281
-
A meta-Analysis of individual participant data reveals an association between circulating levels of IGF-I and prostate cancer risk
-
Travis, R. C., et al. A meta-Analysis of individual participant data reveals an association between circulating levels of IGF-I and prostate cancer risk. Cancer Res. 76, 2288-2300 (2016
-
(2016)
Cancer Res
, vol.76
, pp. 2288-2300
-
-
Travis, R.C.1
-
143
-
-
0032786770
-
Regulation of insulin-like growth factor i in starvation and injury
-
Thissen, J. P., Underwood, L. E., & Ketelslegers, J. M. Regulation of insulin-like growth factor I in starvation and injury. Nutr. Rev. 57, 167-176 (1999
-
(1999)
Nutr. Rev
, vol.57
, pp. 167-176
-
-
Thissen, J.P.1
Underwood, L.E.2
Ketelslegers, J.M.3
-
144
-
-
84899657374
-
IGF binding proteins in cancer: Mechanistic and clinical insights
-
Baxter, R. C. IGF binding proteins in cancer: mechanistic and clinical insights. Nat. Rev. Cancer 14, 329-341 (2014
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 329-341
-
-
Baxter, R.C.1
-
145
-
-
0042412430
-
Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women
-
Key, T. J., et al. Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J. Natl Cancer Inst. 95, 1218-1226 (2003
-
(2003)
J. Natl Cancer Inst
, vol.95
, pp. 1218-1226
-
-
Key, T.J.1
-
146
-
-
84869819669
-
A prospective study of circulating adipokine levels and risk of multiple myeloma
-
Hofmann, J. N., et al. A prospective study of circulating adipokine levels and risk of multiple myeloma. Blood 120, 4418-4420 (2012
-
(2012)
Blood
, vol.120
, pp. 4418-4420
-
-
Hofmann, J.N.1
-
147
-
-
84964894113
-
Prediagnosis plasma adiponectin in relation to colorectal cancer risk according to KRAS mutation status
-
Inamura, K., et al. Prediagnosis plasma adiponectin in relation to colorectal cancer risk according to KRAS mutation status. J. Natl Cancer Inst. 108, http://dx.doi.org/10.1093/jnci/djv363 (2016
-
(2016)
J. Natl Cancer Inst
, vol.108
-
-
Inamura, K.1
-
148
-
-
84872590843
-
A prospective study of plasma adiponectin and pancreatic cancer risk in five US cohorts
-
Bao, Y., et al. A prospective study of plasma adiponectin and pancreatic cancer risk in five US cohorts. J. Natl Cancer Inst. 105, 95-103 (2013
-
(2013)
J. Natl Cancer Inst
, vol.105
, pp. 95-103
-
-
Bao, Y.1
-
149
-
-
84963768563
-
Low levels of circulating adiponectin are associated with multiple myeloma risk in overweight and obese individuals
-
Hofmann, J. N., et al. Low levels of circulating adiponectin are associated with multiple myeloma risk in overweight and obese individuals. Cancer Res. 76, 1935-1941 (2016
-
(2016)
Cancer Res
, vol.76
, pp. 1935-1941
-
-
Hofmann, J.N.1
-
150
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
Arita, Y., et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem. Biophys. Res. Commun. 257, 79-83 (1999
-
(1999)
Biochem. Biophys. Res. Commun
, vol.257
, pp. 79-83
-
-
Arita, Y.1
-
151
-
-
61449113987
-
The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-Activated protein kinase
-
Zakikhani, M., Dowling, R. J., Sonenberg, N., & Pollak, M. N. The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-Activated protein kinase. Cancer Prev. Res. (Phila.) 1, 369-375 (2008
-
(2008)
Cancer Prev. Res. (Phila
, vol.1
, pp. 369-375
-
-
Zakikhani, M.1
Dowling, R.J.2
Sonenberg, N.3
Pollak, M.N.4
-
152
-
-
84877090947
-
Molecular pathways: Adiponectin and leptin signaling in cancer
-
Vansaun, M. N. Molecular pathways: adiponectin and leptin signaling in cancer. Clin. Cancer Res. 19, 1926-1932 (2013
-
(2013)
Clin. Cancer Res
, vol.19
, pp. 1926-1932
-
-
Vansaun, M.N.1
-
153
-
-
84955268118
-
Obesity and cancer: The oil that feeds the flame
-
Font-Burgada, J., Sun, B., & Karin, M. Obesity and cancer: the oil that feeds the flame. Cell. Metabolism 23, 48-62 (2016
-
(2016)
Cell. Metabolism
, vol.23
, pp. 48-62
-
-
Font-Burgada, J.1
Sun, B.2
Karin, M.3
-
154
-
-
84968739477
-
Systemic correlates of white adipose tissue inflammation in early-stage breast cancer
-
Iyengar N. M., et al. Systemic correlates of white adipose tissue inflammation in early-stage breast cancer. Clin. Cancer Res. http://dx.doi.org/10.1158/1078-0432.ccr-15-2239 2015
-
(2015)
Clin. Cancer Res
-
-
Iyengar, N.M.1
-
155
-
-
84942524791
-
Neutrophil ageing is regulated by the microbiome
-
Zhang, D., et al. Neutrophil ageing is regulated by the microbiome. Nature 525, 528-532 (2015
-
(2015)
Nature
, vol.525
, pp. 528-532
-
-
Zhang, D.1
-
156
-
-
84883478660
-
Gut microbiota from twins discordant for obesity modulate metabolism in mice
-
Ridaura, V. K., et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 341, 1241214 (2013
-
(2013)
Science
, vol.341
, pp. 1241214
-
-
Ridaura, V.K.1
-
157
-
-
85018193359
-
Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome
-
Ussar, S., et al. Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome. Cell. Metabolism 22, 516-530 (2015
-
(2015)
Cell. Metabolism
, vol.22
, pp. 516-530
-
-
Ussar, S.1
-
158
-
-
84877822086
-
Metformin inhibits the senescence-Associated secretory phenotype by interfering with IKK/NF ?B activation
-
Moiseeva, O., et al. Metformin inhibits the senescence-Associated secretory phenotype by interfering with IKK/NF ?B activation. Aging Cell 12, 489-498 (2013
-
(2013)
Aging Cell
, vol.12
, pp. 489-498
-
-
Moiseeva, O.1
-
159
-
-
84959432961
-
Metformin ameliorates inflammatory bowel disease by suppression of the STAT3 signaling pathway and regulation of the between Th17/Treg balance
-
Lee, S. Y., et al. Metformin ameliorates inflammatory bowel disease by suppression of the STAT3 signaling pathway and regulation of the between Th17/Treg balance. PLoS ONE 10, e0135858 (2015
-
(2015)
PLoS ONE
, vol.10
, pp. e0135858
-
-
Lee, S.Y.1
-
160
-
-
84949772416
-
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
-
Forslund, K., et al. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature 528, 262-266 (2015
-
(2015)
Nature
, vol.528
, pp. 262-266
-
-
Forslund, K.1
-
161
-
-
84944463475
-
Corticosteroids for the management of cancer-related pain in adults
-
Haywood, A., et al. Corticosteroids for the management of cancer-related pain in adults. Cochrane Database Syst. Rev. 4, CD010756 (2015
-
(2015)
Cochrane Database Syst. Rev
, vol.4
, pp. CD010756
-
-
Haywood, A.1
-
162
-
-
84868611737
-
New mechanisms of glucocorticoid-induced insulin resistance: Make no bones about it
-
Ferris, H. A., & Kahn, C. R. New mechanisms of glucocorticoid-induced insulin resistance: make no bones about it. J. Clin. Invest. 122, 3854-3857 (2012
-
(2012)
J. Clin. Invest
, vol.122
, pp. 3854-3857
-
-
Ferris, H.A.1
Kahn, C.R.2
-
163
-
-
82555187956
-
Diabetes in Cushing syndrome: Basic and clinical aspects
-
Mazziotti, G., Gazzaruso, C., & Giustina, A. Diabetes in Cushing syndrome: basic and clinical aspects. Trends Endocrinol. Metabolism 22, 499-506 (2011
-
(2011)
Trends Endocrinol. Metabolism
, vol.22
, pp. 499-506
-
-
Mazziotti, G.1
Gazzaruso, C.2
Giustina, A.3
-
164
-
-
84876172524
-
The high incidence of steroid-induced hyperglycaemia in hospital
-
Fong, A. C., & Cheung, N. W. The high incidence of steroid-induced hyperglycaemia in hospital. Diabetes Res. Clin. Pract. 99, 277-280 (2013
-
(2013)
Diabetes Res. Clin. Pract
, vol.99
, pp. 277-280
-
-
Fong, A.C.1
Cheung, N.W.2
-
165
-
-
84926250444
-
Cancer-drug induced insulin resistance: Innocent bystander or unusual suspect
-
Ariaans, G., et al. Cancer-drug induced insulin resistance: innocent bystander or unusual suspect. Cancer Treat. Rev. 41, 376-384 (2015
-
(2015)
Cancer Treat. Rev
, vol.41
, pp. 376-384
-
-
Ariaans, G.1
-
166
-
-
67649829689
-
Hyperglycaemia during induction therapy is associated with poorer survival in children with acute lymphocytic leukemia
-
Sonabend, R. Y., et al. Hyperglycaemia during induction therapy is associated with poorer survival in children with acute lymphocytic leukemia. J. Pediatr. 155, 73-78 (2009
-
(2009)
J. Pediatr
, vol.155
, pp. 73-78
-
-
Sonabend, R.Y.1
-
167
-
-
84873713959
-
Glucocorticoids and insulin resistance in children with acute lymphoblastic leukemia
-
Chow, E. J., et al. Glucocorticoids and insulin resistance in children with acute lymphoblastic leukemia. Pediatr. Blood Cancer 60, 621-626 (2013
-
(2013)
Pediatr. Blood Cancer
, vol.60
, pp. 621-626
-
-
Chow, E.J.1
-
168
-
-
84862907716
-
IGF1/insulin receptor kinase inhibition by BMS 536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer
-
Dool, C. J., et al. IGF1/insulin receptor kinase inhibition by BMS 536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer. Endocr. Relat. Cancer 18, 699-709 (2011
-
(2011)
Endocr. Relat. Cancer
, vol.18
, pp. 699-709
-
-
Dool, C.J.1
-
169
-
-
84877141064
-
Management of hyperglycaemia in diabetic patients with hematologic malignancies during dexamethasone therapy
-
Gosmanov, A. R., Goorha, S., Stelts, S., Peng, L., & Umpierrez, G. E. Management of hyperglycaemia in diabetic patients with hematologic malignancies during dexamethasone therapy. Endocr. Pract. 19, 231-235 (2013
-
(2013)
Endocr. Pract
, vol.19
, pp. 231-235
-
-
Gosmanov, A.R.1
Goorha, S.2
Stelts, S.3
Peng, L.4
Umpierrez, G.E.5
-
170
-
-
84907486509
-
Androgen receptor roles in insulin resistance and obesity in males: The linkage of androgen-deprivation therapy to metabolic syndrome
-
Yu, I. C., Lin, H. Y., Sparks, J. D., Yeh, S., & Chang, C. Androgen receptor roles in insulin resistance and obesity in males: the linkage of androgen-deprivation therapy to metabolic syndrome. Diabetes 63, 3180-3188 (2014
-
(2014)
Diabetes
, vol.63
, pp. 3180-3188
-
-
Yu, I.C.1
Lin, H.Y.2
Sparks, J.D.3
Yeh, S.4
Chang, C.5
-
171
-
-
2342644814
-
Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-Aged men
-
Laaksonen, D. E., et al. Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-Aged men. Diabetes Care 27, 1036-1041 (2004
-
(2004)
Diabetes Care
, vol.27
, pp. 1036-1041
-
-
Laaksonen, D.E.1
-
172
-
-
84925845413
-
Quantifying the evidence for the risk of metabolic syndrome and its components following androgen deprivation therapy for prostate cancer: A meta-Analysis
-
Bosco, C., Crawley, D., Adolfsson, J., Rudman, S., & Van Hemelrijck, M. Quantifying the evidence for the risk of metabolic syndrome and its components following androgen deprivation therapy for prostate cancer: a meta-Analysis. PLoS ONE 10, e0117344 (2015
-
(2015)
PLoS ONE
, vol.10
, pp. e0117344
-
-
Bosco, C.1
Crawley, D.2
Adolfsson, J.3
Rudman, S.4
Van Hemelrijck, M.5
-
173
-
-
84894449547
-
Androgen-deprivation therapy and diabetes control among diabetic men with prostate cancer
-
Keating, N. L., Liu, P. H., O'Malley, A. J., Freedland, S. J., & Smith, M. R. Androgen-deprivation therapy and diabetes control among diabetic men with prostate cancer. Eur. Urol. 65, 816-824 (2014
-
(2014)
Eur. Urol
, vol.65
, pp. 816-824
-
-
Keating, N.L.1
Liu, P.H.2
O'Malley, A.J.3
Freedland, S.J.4
Smith, M.R.5
-
174
-
-
84878851433
-
Does comorbidity influence the risk of myocardial infarction or diabetes during androgen-deprivation therapy for prostate cancer?
-
Keating, N. L., O'Malley, A. J., Freedland, S. J., & Smith, M. R. Does comorbidity influence the risk of myocardial infarction or diabetes during androgen-deprivation therapy for prostate cancer? Eur. Urol. 64, 159-166 (2013
-
(2013)
Eur. Urol
, vol.64
, pp. 159-166
-
-
Keating, N.L.1
O'Malley, A.J.2
Freedland, S.J.3
Smith, M.R.4
-
175
-
-
80052225259
-
Insulin increases de novo steroidogenesis in prostate cancer cells
-
Lubik, A. A., et al. Insulin increases de novo steroidogenesis in prostate cancer cells. Cancer Res. 71, 5754-5764 (2011
-
(2011)
Cancer Res
, vol.71
, pp. 5754-5764
-
-
Lubik, A.A.1
-
176
-
-
84861081470
-
The interactions between insulin and androgens in progression to castrate-resistant prostate cancer
-
Gunter, J. H., Lubik, A. A., McKenzie, I., Pollak, M., & Nelson, C. C. The interactions between insulin and androgens in progression to castrate-resistant prostate cancer. Adv. Urol. 2012, 248607 (2012
-
(2012)
Adv. Urol
, vol.2012
, pp. 248607
-
-
Gunter, J.H.1
Lubik, A.A.2
McKenzie, I.3
Pollak, M.4
Nelson, C.C.5
-
177
-
-
33644513730
-
Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
-
Cully, M., You, H., Levine, A. J., & Mak, T. W. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat. Rev. Cancer 6, 184-192 (2006
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 184-192
-
-
Cully, M.1
You, H.2
Levine, A.J.3
Mak, T.W.4
-
178
-
-
84932631687
-
Drugging PI3K in cancer: Refining targets and therapeutic strategies
-
Yap, T. A., Bjerke, L., Clarke, P. A., & Workman, P. Drugging PI3K in cancer: refining targets and therapeutic strategies. Curr. Opin. Pharmacol. 23, 98-107 (2015
-
(2015)
Curr. Opin. Pharmacol
, vol.23
, pp. 98-107
-
-
Yap, T.A.1
Bjerke, L.2
Clarke, P.A.3
Workman, P.4
-
179
-
-
84973167619
-
A phase i study of the AKT inhibitor MK 2206 in combination with hormonal therapy in postmenopausal women with estrogen receptor positive metastatic breast cancer
-
Ma, C. X., et al. A phase I study of the AKT inhibitor MK 2206 in combination with hormonal therapy in postmenopausal women with estrogen receptor positive metastatic breast cancer. Clin. Cancer Res. http://dx.doi.org/10.1158/1078-0432.ccr-15-2160 (2016
-
(2016)
Clin. Cancer Res
-
-
Ma, C.X.1
-
180
-
-
84865074467
-
Management of metabolic effects associated with anticancer agents targeting the PI3K Akt-mTOR pathway
-
Busaidy, N. L., et al. Management of metabolic effects associated with anticancer agents targeting the PI3K Akt-mTOR pathway. J. Clin. Oncol. 30, 2919-2928 (2012
-
(2012)
J. Clin. Oncol
, vol.30
, pp. 2919-2928
-
-
Busaidy, N.L.1
-
181
-
-
84949321820
-
Complications of hyperglycaemia with PI3K AKT-mTOR inhibitors in patients with advanced solid tumours on phase i clinical trials
-
Geuna, E., et al. Complications of hyperglycaemia with PI3K AKT-mTOR inhibitors in patients with advanced solid tumours on phase I clinical trials. Br. J. Cancer 113, 1541-1547 (2015
-
(2015)
Br. J. Cancer
, vol.113
, pp. 1541-1547
-
-
Geuna, E.1
-
182
-
-
84896693794
-
PI3Kd inhibition by idelalisib in patients with relapsed indolent lymphoma
-
Gopal, A. K., et al. PI3Kd inhibition by idelalisib in patients with relapsed indolent lymphoma. N. Engl. J. Med. 370, 1008-1018 (2014
-
(2014)
N. Engl. J. Med
, vol.370
, pp. 1008-1018
-
-
Gopal, A.K.1
-
183
-
-
84945535796
-
Molecular pathways: Clinical applications and future direction of insulin-like growth factor 1 receptor pathway blockade
-
Iams, W. T., & Lovly, C. M. Molecular pathways: clinical applications and future direction of insulin-like growth factor 1 receptor pathway blockade. Clin. Cancer Res. 21, 4270-4277 (2015
-
(2015)
Clin. Cancer Res
, vol.21
, pp. 4270-4277
-
-
Iams, W.T.1
Lovly, C.M.2
-
184
-
-
75749102231
-
Safety, tolerability, and pharmacokinetics of the anti-IGF 1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma
-
Haluska, P., et al. Safety, tolerability, and pharmacokinetics of the anti-IGF 1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma. Cancer Chemother. Pharmacol. 65, 765-773 (2010
-
(2010)
Cancer Chemother. Pharmacol
, vol.65
, pp. 765-773
-
-
Haluska, P.1
-
185
-
-
84892437396
-
Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity
-
Nellemann, B., et al. Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity. Acta Physiol. (Oxford) 210, 392-402 (2014
-
(2014)
Acta Physiol. (Oxford
, vol.210
, pp. 392-402
-
-
Nellemann, B.1
-
186
-
-
84878101513
-
Influence of glucocorticoids and growth hormone on insulin sensitivity in humans
-
Yuen, K. C., Chong, L. E., & Riddle, M. C. Influence of glucocorticoids and growth hormone on insulin sensitivity in humans. Diabet. Med. 30, 651-663 (2013
-
(2013)
Diabet. Med
, vol.30
, pp. 651-663
-
-
Yuen, K.C.1
Chong, L.E.2
Riddle, M.C.3
-
187
-
-
84923188816
-
A phase i study of continuous oral dosing of OSI 906, a dual inhibitor of insulin-like growth factor 1 and insulin receptors, in patients with advanced solid tumors
-
Puzanov, I., et al. A phase I study of continuous oral dosing of OSI 906, a dual inhibitor of insulin-like growth factor 1 and insulin receptors, in patients with advanced solid tumors. Clin. Cancer Res. 21, 701-711 (2015
-
(2015)
Clin. Cancer Res
, vol.21
, pp. 701-711
-
-
Puzanov, I.1
-
188
-
-
84899630091
-
Randomized phase III trial of temsirolimus and bevacizumab versus interferon alfa and bevacizumab in metastatic renal cell carcinoma: INTORACT trial
-
Rini, B. I., et al. Randomized phase III trial of temsirolimus and bevacizumab versus interferon alfa and bevacizumab in metastatic renal cell carcinoma: INTORACT trial. J. Clin. Oncol. 32, 752-759 (2014
-
(2014)
J. Clin. Oncol
, vol.32
, pp. 752-759
-
-
Rini, B.I.1
-
189
-
-
84946607195
-
Nivolumab versus everolimus in advanced renal-cell carcinoma
-
Motzer, R. J., et al. Nivolumab versus everolimus in advanced renal-cell carcinoma. N. Engl. J. Med. 373, 1803-1813 (2015
-
(2015)
N. Engl. J. Med
, vol.373
, pp. 1803-1813
-
-
Motzer, R.J.1
-
190
-
-
84943611415
-
Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo
-
Yang, P., et al. Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo. Sci. Rep. 5, 14959 (2015
-
(2015)
Sci. Rep
, vol.5
, pp. 14959
-
-
Yang, P.1
-
192
-
-
84863078767
-
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer
-
Baselga, J., et al. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. N. Engl. J. Med. 366, 520-529 (2012
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 520-529
-
-
Baselga, J.1
-
193
-
-
68849128718
-
Diabetes mellitus in long-Term survivors of childhood cancer Increased risk associated with radiation therapy: A report for the childhood cancer survivor study
-
Meacham, L. R., et al. Diabetes mellitus in long-Term survivors of childhood cancer. Increased risk associated with radiation therapy: a report for the childhood cancer survivor study. Arch. Intern. Med. 169, 1381-1388 (2009
-
(2009)
Arch. Intern. Med
, vol.169
, pp. 1381-1388
-
-
Meacham, L.R.1
-
194
-
-
84897072839
-
Adult life after childhood cancer in Scandinavia: Diabetes mellitus following treatment for cancer in childhood
-
Holmqvist, A. S., et al. Adult life after childhood cancer in Scandinavia: diabetes mellitus following treatment for cancer in childhood. Eur. J. Cancer 50, 1169-1175 (2014
-
(2014)
Eur. J. Cancer
, vol.50
, pp. 1169-1175
-
-
Holmqvist, A.S.1
-
195
-
-
84907519664
-
Risk of diabetes mellitus in long-Term survivors of Hodgkin lymphoma
-
van Nimwegen, F. A., et al. Risk of diabetes mellitus in long-Term survivors of Hodgkin lymphoma. J. Clin. Oncol. 32, 3257-3263 (2014
-
(2014)
J. Clin. Oncol
, vol.32
, pp. 3257-3263
-
-
Van Nimwegen, F.A.1
-
196
-
-
0142157169
-
Evaluating medication effects outside of clinical trials: New-user designs
-
Ray, W. A. Evaluating medication effects outside of clinical trials: new-user designs. Am. J. Epidemiol. 158, 915-920 (2003
-
(2003)
Am. J. Epidemiol
, vol.158
, pp. 915-920
-
-
Ray, W.A.1
-
197
-
-
84856698481
-
Glucose-lowering agents and the patterns of risk for cancer: A study with the general practice research database and secondary care data
-
van Staa, T. P., Patel, D., Gallagher, A. M., & de Bruin, M. L. Glucose-lowering agents and the patterns of risk for cancer: a study with the General Practice Research Database and secondary care data. Diabetologia 55, 654-665 (2012
-
(2012)
Diabetologia
, vol.55
, pp. 654-665
-
-
Van Staa, T.P.1
Patel, D.2
Gallagher, A.M.3
De Bruin, M.L.4
-
198
-
-
84930089577
-
Cancer and bone fractures in observational follow up of the RECORD study
-
Jones, N. P., Curtis, P. S., & Home, P. D. Cancer and bone fractures in observational follow up of the RECORD study. Acta Diabetol 52, 539-546 (2015
-
(2015)
Acta Diabetol
, vol.52
, pp. 539-546
-
-
Jones, N.P.1
Curtis, P.S.2
Home, P.D.3
-
199
-
-
84980041509
-
NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis
-
Wang, H., et al. NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis. Sci. Transl. Med. 8, 334ra351 (2016
-
(2016)
Sci. Transl. Med
, vol.8
, pp. 334ra351
-
-
Wang, H.1
-
200
-
-
84903157595
-
Pancreatic safety of newer incretin-based therapies: Are the '-Tides' finally turning?
-
Devaraj, S., & Maitra, A. Pancreatic safety of newer incretin-based therapies: are the '-Tides' finally turning? Diabetes 63, 2219-2221 (2014
-
(2014)
Diabetes
, vol.63
, pp. 2219-2221
-
-
Devaraj, S.1
Maitra, A.2
-
201
-
-
84899103659
-
The association of basal insulin glargine and/or n-3 fatty acids with incident cancers in patients with dysglycemia
-
Bordeleau, L., et al. The association of basal insulin glargine and/or n-3 fatty acids with incident cancers in patients with dysglycemia. Diabetes Care 37, 1360-1366 (2014
-
(2014)
Diabetes Care
, vol.37
, pp. 1360-1366
-
-
Bordeleau, L.1
|