Hyperglycemia during Induction Therapy is Associated with Poorer Survival in Children with Acute Lymphocytic Leukemia

Journal of Pediatrics

Volumn 155, Issue 1, 2009, Pages 73-78

  Sonabend, Rona Y ^a   McKay, Siripoom V ^a   Okcu, M Fatih ^a   Yan, Jinrong ^a   Haymond, Morey W ^a   Margolin, Judith F ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINASE; DAUNORUBICIN; DEXAMETHASONE; PREDNISONE; VINCRISTINE;

ACUTE LYMPHOCYTIC LEUKEMIA; ARTICLE; BONE MARROW TRANSPLANTATION; CANCER RELAPSE; CANCER SURVIVAL; CHILD; CONTROLLED STUDY; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS; SCHOOL CHILD;

ANTINEOPLASTIC AGENTS; ASPARAGINASE; BLOOD GLUCOSE; CHILD; CHILD, PRESCHOOL; DAUNORUBICIN; DEXAMETHASONE; ESCHERICHIA COLI; FEMALE; GLUCOCORTICOIDS; HUMANS; HYPERGLYCEMIA; MALE; NEOPLASM RECURRENCE, LOCAL; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PREDNISONE; SEVERITY OF ILLNESS INDEX; VINCRISTINE;

EID: 67649829689     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2009.01.072     Document Type: Article

References (21)

1. Friedmann A.M., and Weinstein H.J. The role of prognostic features in the treatment of childhood acute lymphoblastic leukemia. Oncologist 5 (2000) 321-328
2. Devos P., and Preiser J.C. Tight blood glucose control: a recommendation applicable to any critically ill patient?. Crit Care 8 (2004) 427-429
3. Faustino E.V., and Apkon M. Persistent hyperglycemia in critically ill children. J Pediatr 146 (2005) 30-34
4. Srinivasan V., Spinella P.C., Drott H.R., Roth C.L., Helfaer M.A., and Nadkarni V. Association of timing, duration, and intensity of hyperglycemia with intensive care unit mortality in critically ill children. Pediatr Crit Care Med 5 (2004) 329-336
5. Pittas A.G., Siegel R.D., and Lau J. Insulin therapy for critically ill hospitalized patients: a meta-analysis of randomized controlled trials. Arch Intern Med 164 (2004) 2005-2011
6. van den Berghe G., Wouters P., Weekers F., Verwaest C., Bruyninckx F., Schetz M., et al. Intensive insulin therapy in the critically ill patients. N Engl J Med 345 (2001) 1359-1367
7. Vanhorebeek I., Langouche L., and Van den Berghe G. Glycemic and nonglycemic effects of insulin: how do they contribute to a better outcome of critical illness?. Curr Opin Crit Care 11 (2005) 304-311
8. Ali N.A., O'Brien Jr. J.M., Blum W., Byrd J.C., Klisovic R.B., Marcucci G., et al. Hyperglycemia in patients with acute myeloid leukemia is associated with increased hospital mortality. Cancer 110 (2007) 96-102
9. Weiser M.A., Cabanillas M.E., Konopleva M., Thomas D.A., Pierce S.A., Escalante C.P., et al. Relation between the duration of remission and hyperglycemia during induction chemotherapy for acute lymphocytic leukemia with a hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone/methotrexate-cytarabine regimen. Cancer 100 (2004) 1179-1185
10. Sonabend R.Y., McKay S.V., Okcu M.F., Yan J., Haymond M.W., and Margolin J.F. Hyperglycemia during induction therapy is associated with increased infectious complications in childhood acute lymphocytic leukemia. Pediatr Blood Cancer 51 (2008) 387-392
11. Smith M., Arthur D., Camitta B., Carroll A.J., Crist W., Gaynon P., et al. Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia. J Clin Oncol 14 (1996) 18-24
12. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 26 Suppl 1 (2003) S5-20
13. Gabir M.M., Hanson R.L., Dabelea D., Imperatore G., Roumain J., Bennett P.H., et al. The 1997 American Diabetes Association and 1999 World Health Organization criteria for hyperglycemia in the diagnosis and prediction of diabetes. Diabetes Care 23 (2000) 1108-1112
14. Jee S.H., Ohrr H., Sull J.W., Yun J.E., Ji M., and Samet J.M. Fasting serum glucose level and cancer risk in Korean men and women. JAMA 293 (2005) 194-202
15. Chiu B.C., Gapstur S.M., Greenland P., Wang R., and Dyer A. Body mass index, abnormal glucose metabolism, and mortality from hematopoietic cancer. Cancer Epidemiol Biomarkers Prev 15 (2006) 2348-2354
16. Cetin M., Yetgin S., Kara A., Tuncer A.M., Gunay M., Gumruk F., et al. Hyperglycemia, ketoacidosis and other complications of L-asparaginase in children with acute lymphoblastic leukemia. J Med 25 (1994) 219-229
17. Asensio C., Muzzin P., and Rohner-Jeanrenaud F. Role of glucocorticoids in the physiopathology of excessive fat deposition and insulin resistance. Int J Obes Relat Metab Disord 28 Suppl 4 (2004) S45-S52
18. Pui C.H., Burghen G.A., Bowman W.P., and Aur R.J. Risk factors for hyperglycemia in children with leukemia receiving L-asparaginase and prednisone. J Pediatr 99 (1981) 46-50
19. Baillargeon J., Langevin A.M., Mullins J., Ferry Jr. R.J., DeAngulo G., Thomas P.J., et al. Transient hyperglycemia in Hispanic children with acute lymphoblastic leukemia. Pediatr Blood Cancer 45 (2005) 960-963
20. de Vegt F., Dekker J.M., Jager A., Hienkens E., Kostense P.J., Stehouwer C.D., et al. Relation of impaired fasting and postload glucose with incident type 2 diabetes in a Dutch population: The Hoorn Study. JAMA 285 (2001) 2109-2113
21. Ceriello A., Hanefeld M., Leiter L., Monnier L., Moses A., Owens D., et al. Postprandial glucose regulation and diabetic complications. Arch Intern Med 164 (2004) 2090-2095