Epistasis and the dynamics of reversion in molecular evolution

Genetics

Volumn 203, Issue 3, 2016, Pages 1335-1351

  McCandlish, David M ^a   Shah, Premal ^b   Plotkin, Joshua B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Entrenchment; Fitness landscape; Reversible Markov chain; Weak mutation

Indexed keywords

ARTICLE; EPISTASIS; GENOTYPE; HAZARD; MARKOV CHAIN; MOLECULAR EVOLUTION; MUTATION RATE; PRIORITY JOURNAL; REVERTANT; TIME; AMINO ACID SUBSTITUTION; BIOLOGICAL MODEL; GENETIC SELECTION; GENETICS; MUTATION; REPRODUCTIVE FITNESS;

AMINO ACID SUBSTITUTION; EPISTASIS, GENETIC; EVOLUTION, MOLECULAR; GENETIC FITNESS; GENOTYPE; MODELS, GENETIC; MUTATION; SELECTION, GENETIC;

EID: 84979955129     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.116.188961     Document Type: Article

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