DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 30, 2016, Pages E4311-E4319

  Hampp, Stephanie ^a   Kiessling, Tina ^a   Buechle, Kerstin ^a   Mansilla, Sabrina F ^b   Thomale, Jürgen ^c   Rall, Melanie ^a   Ahn, Jinwoo ^d   Pospiech, Helmut ^e,f   Gottifredi, Vanesa ^b   Wiesmüller, Lisa ^g  

^a UNIVERSITY OF ULM   (Germany)

^b Fundación Instituto Leloir Instituto de Investigaciones Bioquimicas de Buenos Aires ^*  (Argentina)

^c UNIVERSITY OF ESSEN MEDICAL SCHOOL   (Germany)

^d Columbia University ^*  (United States)

^e FRITZ LIPMANN INSTITUTE   (Germany)

^f UNIVERSITY OF OULU   (Finland)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

DNA damage bypass; DNA polymerase idling; Nascent DNA elongation; P53; Polymerase

Indexed keywords

CARRIER PROTEIN; DNA; DNA POLYMERASE; EXONUCLEASE; HELICASE LIKE TRANSCRIPTION FACTOR; PROTEIN A; PROTEIN P53; SWI SNF CATALYTIC SUBUNIT TRANSLOCASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER RAN BINDING DOMAIN CONTAINING 3; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE; DNA HELICASE; DNA POLYMERASE IOTA; HLTF PROTEIN, HUMAN; REPLICATION FACTOR A; ZRANB3 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVE SITE; ENZYME DEFICIENCY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MUTANT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRESS; WILD TYPE; CELL CULTURE; CHEMISTRY; CONFORMATION; DNA REPAIR; GENETICS; HOMOLOGOUS RECOMBINATION; K-562 CELL LINE; METABOLISM; RNA INTERFERENCE; TUMOR CELL LINE;

CELL LINE, TUMOR; CELLS, CULTURED; DNA; DNA DAMAGE; DNA HELICASES; DNA REPAIR; DNA REPLICATION; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; HOMOLOGOUS RECOMBINATION; HUMANS; K562 CELLS; NUCLEIC ACID CONFORMATION; REPLICATION PROTEIN A; RNA INTERFERENCE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84979642998     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1605828113     Document Type: Article

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