메뉴 건너뛰기




Volumn 24, Issue 1, 2014, Pages 107-113

Replicative DNA polymerase mutations in cancer

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; PROTEIN POLD1; PROTEIN POLE; SPLEEN EXONUCLEASE; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84896739540     PISSN: 0959437X     EISSN: 18790380     Source Type: Journal    
DOI: 10.1016/j.gde.2013.12.005     Document Type: Review
Times cited : (97)

References (49)
  • 1
    • 18044384092 scopus 로고    scopus 로고
    • DNA polymerases that propagate the eukaryotic DNA replication fork
    • Garg P., Burgers P.M. DNA polymerases that propagate the eukaryotic DNA replication fork. Crit Rev Biochem Mol Biol 2005, 40:115-128.
    • (2005) Crit Rev Biochem Mol Biol , vol.40 , pp. 115-128
    • Garg, P.1    Burgers, P.M.2
  • 2
    • 22244478079 scopus 로고    scopus 로고
    • Cellular DNA replicases: components and dynamics at the replication fork
    • Johnson A., O'Donnell M. Cellular DNA replicases: components and dynamics at the replication fork. Annu Rev Biochem 2005, 74:283-315.
    • (2005) Annu Rev Biochem , vol.74 , pp. 283-315
    • Johnson, A.1    O'Donnell, M.2
  • 3
    • 10044241865 scopus 로고    scopus 로고
    • Functions of DNA polymerases
    • Bebenek K., Kunkel T.A. Functions of DNA polymerases. Adv Protein Chem 2004, 69:137-165.
    • (2004) Adv Protein Chem , vol.69 , pp. 137-165
    • Bebenek, K.1    Kunkel, T.A.2
  • 4
    • 77949568225 scopus 로고    scopus 로고
    • DNA polymerase proofreading: multiple roles maintain genome stability
    • Reha-Krantz L.J. DNA polymerase proofreading: multiple roles maintain genome stability. Biochim Biophys Acta 2010, 1804:1049-1063.
    • (2010) Biochim Biophys Acta , vol.1804 , pp. 1049-1063
    • Reha-Krantz, L.J.1
  • 5
    • 0026333726 scopus 로고
    • Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene
    • Chung D.W., Zhang J.A., Tan C.K., Davie E.W., So A.G., Downey K.M. Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene. Proc Natl Acad Sci U S A 1991, 88:11197-11201.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 11197-11201
    • Chung, D.W.1    Zhang, J.A.2    Tan, C.K.3    Davie, E.W.4    So, A.G.5    Downey, K.M.6
  • 7
    • 34447336941 scopus 로고    scopus 로고
    • Yeast DNA polymerase epsilon participates in leading-strand DNA replication
    • Pursell Z.F., Isoz I., Lundstrom E.B., Johansson E., Kunkel T.A. Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Science 2007, 317:127-130.
    • (2007) Science , vol.317 , pp. 127-130
    • Pursell, Z.F.1    Isoz, I.2    Lundstrom, E.B.3    Johansson, E.4    Kunkel, T.A.5
  • 8
    • 30944452765 scopus 로고    scopus 로고
    • Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta
    • Pavlov Y.I., Frahm C., Nick McElhinny S.A., Niimi A., Suzuki M., Kunkel T.A. Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta. Curr Biol 2006, 16:202-207.
    • (2006) Curr Biol , vol.16 , pp. 202-207
    • Pavlov, Y.I.1    Frahm, C.2    Nick McElhinny, S.A.3    Niimi, A.4    Suzuki, M.5    Kunkel, T.A.6
  • 9
    • 0026004621 scopus 로고
    • Eukaryotic DNA polymerase amino acid sequence required for 3'-5' exonuclease activity
    • Morrison A., Bell J.B., Kunkel T.A., Sugino A. Eukaryotic DNA polymerase amino acid sequence required for 3'-5' exonuclease activity. Proc Natl Acad Sci U S A 1991, 88:9473-9477.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 9473-9477
    • Morrison, A.1    Bell, J.B.2    Kunkel, T.A.3    Sugino, A.4
  • 10
    • 0025900035 scopus 로고
    • The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication
    • Simon M., Giot L., Faye G. The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication. EMBO J 1991, 10:2165-2170.
    • (1991) EMBO J , vol.10 , pp. 2165-2170
    • Simon, M.1    Giot, L.2    Faye, G.3
  • 11
    • 63249130106 scopus 로고    scopus 로고
    • Polymerase dynamics at the eukaryotic DNA replication fork
    • Burgers P.M. Polymerase dynamics at the eukaryotic DNA replication fork. J Biol Chem 2009, 284:4041-4045.
    • (2009) J Biol Chem , vol.284 , pp. 4041-4045
    • Burgers, P.M.1
  • 12
    • 77954328102 scopus 로고    scopus 로고
    • Increased mutagenesis and unique mutation signature associated with mitotic gene conversion
    • Hicks W.M., Kim M., Haber J.E. Increased mutagenesis and unique mutation signature associated with mitotic gene conversion. Science 2010, 329:82-85.
    • (2010) Science , vol.329 , pp. 82-85
    • Hicks, W.M.1    Kim, M.2    Haber, J.E.3
  • 13
    • 33845496081 scopus 로고    scopus 로고
    • Roles of DNA polymerases in replication, repair, and recombination in eukaryotes
    • Pavlov Y.I., Shcherbakova P.V., Rogozin I.B. Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. Int Rev Cytol 2006, 255:41-132.
    • (2006) Int Rev Cytol , vol.255 , pp. 41-132
    • Pavlov, Y.I.1    Shcherbakova, P.V.2    Rogozin, I.B.3
  • 14
    • 0034595502 scopus 로고    scopus 로고
    • Evidence from mutational specificity studies that yeast DNA polymerases delta and epsilon replicate different DNA strands at an intracellular replication fork
    • Karthikeyan R., Vonarx E.J., Straffon A.F., Simon M., Faye G., Kunz B.A. Evidence from mutational specificity studies that yeast DNA polymerases delta and epsilon replicate different DNA strands at an intracellular replication fork. J Mol Biol 2000, 299:405-419.
    • (2000) J Mol Biol , vol.299 , pp. 405-419
    • Karthikeyan, R.1    Vonarx, E.J.2    Straffon, A.F.3    Simon, M.4    Faye, G.5    Kunz, B.A.6
  • 15
    • 0037008736 scopus 로고    scopus 로고
    • The DNA polymerase domain of pol(epsilon) is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae
    • Ohya T., Kawasaki Y., Hiraga S., Kanbara S., Nakajo K., Nakashima N., Suzuki A., Sugino A. The DNA polymerase domain of pol(epsilon) is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae. J Biol Chem 2002, 277:28099-28108.
    • (2002) J Biol Chem , vol.277 , pp. 28099-28108
    • Ohya, T.1    Kawasaki, Y.2    Hiraga, S.3    Kanbara, S.4    Nakajo, K.5    Nakashima, N.6    Suzuki, A.7    Sugino, A.8
  • 16
    • 0032925857 scopus 로고    scopus 로고
    • Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast
    • Tran H.T., Degtyareva N.P., Gordenin D.A., Resnick M.A. Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast. Genetics 1999, 152:47-59.
    • (1999) Genetics , vol.152 , pp. 47-59
    • Tran, H.T.1    Degtyareva, N.P.2    Gordenin, D.A.3    Resnick, M.A.4
  • 17
    • 0030962035 scopus 로고    scopus 로고
    • Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants
    • Tran H.T., Keen J.D., Kricker M., Resnick M.A., Gordenin D.A. Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants. Mol Cell Biol 1997, 17:2859-2865.
    • (1997) Mol Cell Biol , vol.17 , pp. 2859-2865
    • Tran, H.T.1    Keen, J.D.2    Kricker, M.3    Resnick, M.A.4    Gordenin, D.A.5
  • 18
    • 54249092768 scopus 로고    scopus 로고
    • Dividing the workload at a eukaryotic replication fork
    • Kunkel T.A., Burgers P.M. Dividing the workload at a eukaryotic replication fork. Trends Cell Biol 2008, 18:521-527.
    • (2008) Trends Cell Biol , vol.18 , pp. 521-527
    • Kunkel, T.A.1    Burgers, P.M.2
  • 19
    • 0029670573 scopus 로고    scopus 로고
    • 3'-5' exonucleases of DNA polymerases epsilon and delta correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae
    • Shcherbakova P.V., Pavlov Y.I. 3'-5' exonucleases of DNA polymerases epsilon and delta correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae. Genetics 1996, 142:717-726.
    • (1996) Genetics , vol.142 , pp. 717-726
    • Shcherbakova, P.V.1    Pavlov, Y.I.2
  • 21
    • 0038371133 scopus 로고    scopus 로고
    • Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast
    • Pavlov Y.I., Mian I.M., Kunkel T.A. Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast. Curr Biol 2003, 13:744-748.
    • (2003) Curr Biol , vol.13 , pp. 744-748
    • Pavlov, Y.I.1    Mian, I.M.2    Kunkel, T.A.3
  • 22
    • 0036345594 scopus 로고    scopus 로고
    • Yeast origins establish a strand bias for replicational mutagenesis
    • Pavlov Y.I., Newlon C.S., Kunkel T.A. Yeast origins establish a strand bias for replicational mutagenesis. Mol Cell 2002, 10:207-213.
    • (2002) Mol Cell , vol.10 , pp. 207-213
    • Pavlov, Y.I.1    Newlon, C.S.2    Kunkel, T.A.3
  • 23
    • 0034809479 scopus 로고    scopus 로고
    • Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities
    • Greene C.N., Jinks-Robertson S. Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities. Genetics 2001, 159:65-75.
    • (2001) Genetics , vol.159 , pp. 65-75
    • Greene, C.N.1    Jinks-Robertson, S.2
  • 24
    • 0027417017 scopus 로고
    • Pathway correcting DNA replication errors in Saccharomyces cerevisiae
    • Morrison A., Johnson A.L., Johnston L.H., Sugino A. Pathway correcting DNA replication errors in Saccharomyces cerevisiae. EMBO J 1993, 12:1467-1473.
    • (1993) EMBO J , vol.12 , pp. 1467-1473
    • Morrison, A.1    Johnson, A.L.2    Johnston, L.H.3    Sugino, A.4
  • 25
    • 77952523879 scopus 로고    scopus 로고
    • Case series: acute tumor lysis syndrome in mutator mice with disseminated lymphoblastic lymphoma
    • Treuting P.M., Albertson T.M., Preston B.D. Case series: acute tumor lysis syndrome in mutator mice with disseminated lymphoblastic lymphoma. Toxicol Pathol 2010, 38:476-485.
    • (2010) Toxicol Pathol , vol.38 , pp. 476-485
    • Treuting, P.M.1    Albertson, T.M.2    Preston, B.D.3
  • 26
    • 84887199310 scopus 로고    scopus 로고
    • Human Pol varepsilon-dependent replication errors and the influence of mismatch repair on their correction
    • Agbor A.A., Goksenin A.Y., Lecompte K.G., Hans S.H., Pursell Z.F. Human Pol varepsilon-dependent replication errors and the influence of mismatch repair on their correction. DNA Repair (Amst) 2013, 12:954-963.
    • (2013) DNA Repair (Amst) , vol.12 , pp. 954-963
    • Agbor, A.A.1    Goksenin, A.Y.2    Lecompte, K.G.3    Hans, S.H.4    Pursell, Z.F.5
  • 27
    • 45449103427 scopus 로고    scopus 로고
    • DNA mismatch repair: molecular mechanism, cancer, and ageing
    • Hsieh P., Yamane K. DNA mismatch repair: molecular mechanism, cancer, and ageing. Mech Ageing Dev 2008, 129:391-407.
    • (2008) Mech Ageing Dev , vol.129 , pp. 391-407
    • Hsieh, P.1    Yamane, K.2
  • 28
    • 4944240144 scopus 로고    scopus 로고
    • Genetic predisposition to colorectal cancer
    • de la Chapelle A. Genetic predisposition to colorectal cancer. Nat Rev Cancer 2004, 4:769-780.
    • (2004) Nat Rev Cancer , vol.4 , pp. 769-780
    • de la Chapelle, A.1
  • 30
    • 84877769352 scopus 로고    scopus 로고
    • Germline and somatic polymerase epsilon and delta mutations define a new class of hypermutated colorectal and endometrial cancers
    • Briggs S., Tomlinson I. Germline and somatic polymerase epsilon and delta mutations define a new class of hypermutated colorectal and endometrial cancers. J Pathol 2013, 230:148-153.
    • (2013) J Pathol , vol.230 , pp. 148-153
    • Briggs, S.1    Tomlinson, I.2
  • 35
    • 78651103864 scopus 로고    scopus 로고
    • Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk
    • Monsees G.M., Kraft P., Chanock S.J., Hunter D.J., Han J. Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. Breast Cancer Res Treat 2011, 125:207-214.
    • (2011) Breast Cancer Res Treat , vol.125 , pp. 207-214
    • Monsees, G.M.1    Kraft, P.2    Chanock, S.J.3    Hunter, D.J.4    Han, J.5
  • 36
    • 3042829470 scopus 로고    scopus 로고
    • Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes
    • Sigurdson A.J., Hauptmann M., Chatterjee N., Alexander B.H., Doody M.M., Rutter J.L., Struewing J.P. Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes. BMC Cancer 2004, 4:9.
    • (2004) BMC Cancer , vol.4 , pp. 9
    • Sigurdson, A.J.1    Hauptmann, M.2    Chatterjee, N.3    Alexander, B.H.4    Doody, M.M.5    Rutter, J.L.6    Struewing, J.P.7
  • 40
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • Cancer Genome Atlas N
    • Cancer Genome Atlas N Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012, 487:330-337.
    • (2012) Nature , vol.487 , pp. 330-337
  • 41
    • 84873840105 scopus 로고    scopus 로고
    • The burden of faulty proofreading in colon cancer
    • Seshagiri S. The burden of faulty proofreading in colon cancer. Nat Genet 2013, 45:121-122.
    • (2013) Nat Genet , vol.45 , pp. 121-122
    • Seshagiri, S.1
  • 43
    • 0037040932 scopus 로고    scopus 로고
    • Human DNA polymerase epsilon colocalizes with proliferating cell nuclear antigen and DNA replication late, but not early, in S phase
    • Fuss J., Linn S. Human DNA polymerase epsilon colocalizes with proliferating cell nuclear antigen and DNA replication late, but not early, in S phase. J Biol Chem 2002, 277:8658-8666.
    • (2002) J Biol Chem , vol.277 , pp. 8658-8666
    • Fuss, J.1    Linn, S.2
  • 47
    • 0023754044 scopus 로고
    • Amino acid changes coded by bacteriophage T4 DNA polymerase mutator mutants. Relating structure to function
    • Reha-Krantz L.J. Amino acid changes coded by bacteriophage T4 DNA polymerase mutator mutants. Relating structure to function. J Mol Biol 1988, 202:711-724.
    • (1988) J Mol Biol , vol.202 , pp. 711-724
    • Reha-Krantz, L.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.