SCOPUS 정보 검색 플랫폼

Volumn 60, Issue 8, 2016, Pages 4471-4481

Large-scale screening and identification of novel ebola virus and Marburg virus entry inhibitors

(14) Anantpadma, Manu a Kouznetsova, Jennifer b Wang, Hang b Huang, Ruili b Kolokoltsov, Andrey e,f Guha, Rajarshi b Lindstrom, Aaron R c Shtanko, Olena a Simeonov, Anton b Maloney, David J b Maury, Wendy d LaCount, Douglas J c Jadhav, Ajit b Davey, Robert A a

a SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (United States)

b NATIONAL INSTITUTES OF HEALTH (United States)

c PURDUE UNIVERSITY (United States)

d UNIVERSITY OF IOWA (United States)

e University of Texas Medical Branch School of Medicine (United States)

f Pharmeco LLC (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; ANTIVIRUS AGENT; BAFILOMYCIN A1; CHLORPROMAZINE; EBOLA VIRUS ENTRY INHIBITOR; MARBURG VIRUS ENTRY INHIBITOR; MLS 000078751; MLS 000394177; MLS 000534476; MLS 000554255; MLS 000555232; MLS 000730532; MLS 000733230; MLS 000762907; MLS 001101371; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG STRUCTURE; EBOLAVIRUS; EC50; ENDOSOME; FEMALE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC50; MARBURGVIRUS; MOLECULAR LIBRARY; NONHUMAN; PINOCYTOSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STRUCTURE ANALYSIS; VIRUS INHIBITION; ANIMAL; CELL LINE; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; GENETICS; HELA CELL LINE; METABOLISM; VERO CELL LINE;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CERCOPITHECUS AETHIOPS; EBOLAVIRUS; HELA CELLS; HUMANS; MARBURGVIRUS; VERO CELLS;

EID: 84979287772 PISSN: 00664804 EISSN: 10986596 Source Type: Journal
DOI: 10.1128/AAC.00543-16 Document Type: Article

Times cited : (45)

References (54)

1
- 84897065474
- Discussions and decisions of the 2012-2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012-June 2013
- Bukreyev AA, Chandran K, Dolnik O, Dye JM, Ebihara H, Leroy EM, Muhlberger E, Netesov SV, Patterson JL, Paweska JT, Saphire EO, Smither SJ, Takada A, Towner JS, Volchkov VE, Warren TK, Kuhn JH. 2014. Discussions and decisions of the 2012-2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012-June 2013. Arch Virol 159:821-830. http://dx.doi.org/10.1007/s00705-013-1846-9.
- (2014) Arch Virol , vol.159 , pp. 821-830
- Bukreyev, A.A.¹ Chandran, K.² Dolnik, O.³ Dye, J.M.⁴ Ebihara, H.⁵ Leroy, E.M.⁶ Muhlberger, E.⁷ Netesov, S.V.⁸ Patterson, J.L.⁹ Paweska, J.T.¹⁰ Saphire, E.O.¹¹ Smither, S.J.¹² Takada, A.¹³ Towner, J.S.¹⁴ Volchkov, V.E.¹⁵ Warren, T.K.¹⁶ Kuhn, J.H.¹⁷

2
- 77953351485
- Ebola and Marburg hemorrhagic fever
- Hartman AL, Towner JS, Nichol ST. 2010. Ebola and Marburg hemorrhagic fever. Clin Lab Med 30:161-177. http://dx.doi.org/10.1016/j.cll.2009.12.001.
- (2010) Clin Lab Med , vol.30 , pp. 161-177
- Hartman, A.L.¹ Towner, J.S.² Nichol, S.T.³

3
- 84923553227
- Ebola and Marburg haemorrhagic fever
- Rougeron V, Feldmann H, Grard G, Becker S, Leroy EM. 2015. Ebola and Marburg haemorrhagic fever. J Clin Virol 64:111-119. http://dx.doi.org/10.1016/j.jcv.2015.01.014.
- (2015) J Clin Virol , vol.64 , pp. 111-119
- Rougeron, V.¹ Feldmann, H.² Grard, G.³ Becker, S.⁴ Leroy, E.M.⁵

4
- 79952590815
- Identification of a small-molecule entry inhibitor for filoviruses
- Basu A, Li B, Mills DM, Panchal RG, Cardinale SC, Butler MM, Peet NP, Majgier-Baranowska H, Williams JD, Patel I, Moir DT, Bavari S, Ray R, Farzan MR, Rong L, Bowlin TL. 2011. Identification of a small-molecule entry inhibitor for filoviruses. J Virol 85:3106-3119. http://dx.doi.org/10.1128/JVI.01456-10.
- (2011) J Virol , vol.85 , pp. 3106-3119
- Basu, A.¹ Li, B.² Mills, D.M.³ Panchal, R.G.⁴ Cardinale, S.C.⁵ Butler, M.M.⁶ Peet, N.P.⁷ Majgier-Baranowska, H.⁸ Williams, J.D.⁹ Patel, I.¹⁰ Moir, D.T.¹¹ Bavari, S.¹² Ray, R.¹³ Farzan, M.R.¹⁴ Rong, L.¹⁵ Bowlin, T.L.¹⁶

5
- 84940997614
- Inhibition of Ebola and Marburg viral entry by G protein-coupled receptor antagonists
- Cheng H, Lear-Rooney CM, Johansen L, Varhegyi E, Chen ZW, Olinger GG, Rong L. 2015. Inhibition of Ebola and Marburg viral entry by G protein-coupled receptor antagonists. J Virol 89:9932-9938. http://dx.doi.org/10.1128/JVI.01337-15.
- (2015) J Virol , vol.89 , pp. 9932-9938
- Cheng, H.¹ Lear-Rooney, C.M.² Johansen, L.³ Varhegyi, E.⁴ Chen, Z.W.⁵ Olinger, G.G.⁶ Rong, L.⁷

6
- 84908404590
- The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus
- Garrison AR, Giomarelli BG, Lear-Rooney CM, Saucedo CJ, Yellayi S, Krumpe LR, Rose M, Paragas J, Bray M, Olinger GG, Jr, McMahon JB, Huggins J, O'Keefe BR. 2014. The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus. Antiviral Res 112:1-7. http://dx.doi.org/10.1016/j.antiviral.2014.09.012.
- (2014) Antiviral Res , vol.112 , pp. 1-7
- Garrison, A.R.¹ Giomarelli, B.G.² Lear-Rooney, C.M.³ Saucedo, C.J.⁴ Yellayi, S.⁵ Krumpe, L.R.⁶ Rose, M.⁷ Paragas, J.⁸ Bray, M.⁹ Olinger, G.G.¹⁰ McMahon, J.B.¹¹ Huggins, J.¹² O'Keefe, B.R.¹³

7
- 84908576988
- Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against Ebola virus and Marburg virus: Results of two single-ascending-dose studies
- Heald AE, Iversen PL, Saoud JB, Sazani P, Charleston JS, Axtelle T, Wong M, Smith WB, Vutikullird A, Kaye E. 2014. Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against Ebola virus and Marburg virus: results of two single-ascending-dose studies. Antimicrob Agents Chemother 58:6639-6647. http://dx.doi.org/10.1128/AAC.03442-14.
- (2014) Antimicrob Agents Chemother , vol.58 , pp. 6639-6647
- Heald, A.E.¹ Iversen, P.L.² Saoud, J.B.³ Sazani, P.⁴ Charleston, J.S.⁵ Axtelle, T.⁶ Wong, M.⁷ Smith, W.B.⁸ Vutikullird, A.⁹ Kaye, E.¹⁰

8
- 84924964870
- Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs
- Kouznetsova J, Sun W, Martínez-Romero C, Tawa G, Shinn P, Chen CZ, Schimmer A, Sanderson P, McKew JC, Zheng W, García-Sastre A. 2014. Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs. Emerg Microbes Infect 3:e84. http://dx.doi.org/10.1038/emi.2014.88.
- (2014) Emerg Microbes Infect , vol.3 , pp. e84
- Kouznetsova, J.¹ Sun, W.² Martínez-Romero, C.³ Tawa, G.⁴ Shinn, P.⁵ Chen, C.Z.⁶ Schimmer, A.⁷ Sanderson, P.⁸ McKew, J.C.⁹ Zheng, W.¹⁰ García-Sastre, A.¹¹

9
- 84880544466
- FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection
- Johansen LM, Brannan JM, Delos SE, Shoemaker CJ, Stossel A, Lear C, Hoffstrom BG, Dewald LE, Schornberg KL, Scully C, Lehar J, Hensley LE, White JM, Olinger GG. 2013. FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection. Sci Transl Med 5:190ra179. http://dx.doi.org/10.1126/scitranslmed.3005471.
- (2013) Sci Transl Med , vol.5
- Johansen, L.M.¹ Brannan, J.M.² Delos, S.E.³ Shoemaker, C.J.⁴ Stossel, A.⁵ Lear, C.⁶ Hoffstrom, B.G.⁷ Dewald, L.E.⁸ Schornberg, K.L.⁹ Scully, C.¹⁰ Lehar, J.¹¹ Hensley, L.E.¹² White, J.M.¹³ Olinger, G.G.¹⁴

10
- 84930456828
- A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity
- Johansen LM, DeWald LE, Shoemaker CJ, Hoffstrom BG, Lear-Rooney CM, Stossel A, Nelson E, Delos SE, Simmons JA, Grenier JM, Pierce LT, Pajouhesh H, Lehar J, Hensley LE, Glass PJ, White JM, Olinger GG. 2015. A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity. Sci Transl Med 7:290ra289. http://dx.doi.org/10.1126/scitranslmed.aaa5597.
- (2015) Sci Transl Med , vol.7
- Johansen, L.M.¹ DeWald, L.E.² Shoemaker, C.J.³ Hoffstrom, B.G.⁴ Lear-Rooney, C.M.⁵ Stossel, A.⁶ Nelson, E.⁷ Delos, S.E.⁸ Simmons, J.A.⁹ Grenier, J.M.¹⁰ Pierce, L.T.¹¹ Pajouhesh, H.¹² Lehar, J.¹³ Hensley, L.E.¹⁴ Glass, P.J.¹⁵ White, J.M.¹⁶ Olinger, G.G.¹⁷

11
- 84901313870
- Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells
- Johnson JC, Martinez O, Honko AN, Hensley LE, Olinger GG, Basler CF. 2014. Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells. Antiviral Res 107:102-109. http://dx.doi.org/10.1016/j.antiviral.2014.04.014.
- (2014) Antiviral Res , vol.107 , pp. 102-109
- Johnson, J.C.¹ Martinez, O.² Honko, A.N.³ Hensley, L.E.⁴ Olinger, G.G.⁵ Basler, C.F.⁶

12
- 84922785429
- High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses
- Mudhasani R, Kota KP, Retterer C, Tran JP, Whitehouse CA, Bavari S. 2014. High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses. PLoS Negl Trop Dis 8:e3095. http://dx.doi.org/10.1371/journal.pntd.0003095.
- (2014) PLoS Negl Trop Dis , vol.8 , pp. e3095
- Mudhasani, R.¹ Kota, K.P.² Retterer, C.³ Tran, J.P.⁴ Whitehouse, C.A.⁵ Bavari, S.⁶

13
- 84907263545
- Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
- Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti JB, Fausther-Bovendo H, Wei H, Aviles J, Hiatt E, Johnson A, Morton J, Swope K, Bohorov O, Bohorova N, Goodman C, Kim D, Pauly MH, Velasco J, Pettitt J, Olinger GG, Whaley K, Xu B, Strong JE, Zeitlin L, Kobinger GP. 2014. Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature 514:47-53. http://dx.doi.org/10.1038/nature13777.
- (2014) Nature , vol.514 , pp. 47-53
- Qiu, X.¹ Wong, G.² Audet, J.³ Bello, A.⁴ Fernando, L.⁵ Alimonti, J.B.⁶ Fausther-Bovendo, H.⁷ Wei, H.⁸ Aviles, J.⁹ Hiatt, E.¹⁰ Johnson, A.¹¹ Morton, J.¹² Swope, K.¹³ Bohorov, O.¹⁴ Bohorova, N.¹⁵ Goodman, C.¹⁶ Kim, D.¹⁷ Pauly, M.H.¹⁸ Velasco, J.¹⁹ Pettitt, J.²⁰ more..

14
- 84923815384
- Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment
- Sakurai Y, Kolokoltsov AA, Chen CC, Tidwell MW, Bauta WE, Klugbauer N, Grimm C, Wahl-Schott C, Biel M, Davey RA. 2015. Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment. Science 347:995-998. http://dx.doi.org/10.1126/science.1258758.
- (2015) Science , vol.347 , pp. 995-998
- Sakurai, Y.¹ Kolokoltsov, A.A.² Chen, C.C.³ Tidwell, M.W.⁴ Bauta, W.E.⁵ Klugbauer, N.⁶ Grimm, C.⁷ Wahl-Schott, C.⁸ Biel, M.⁹ Davey, R.A.¹⁰

15
- 84942288585
- Amiodarone and metabolite MDEA inhibit Ebola virus infection by interfering with the viral entry process
- Salata C, Baritussio A, Munegato D, Calistri A, Ha HR, Bigler L, Fabris F, Parolin C, Palu G, Mirazimi A. 2015. Amiodarone and metabolite MDEA inhibit Ebola virus infection by interfering with the viral entry process. Pathog Dis 73:ffv032. http://dx.doi.org/10.1093/femspd/ftv032.
- (2015) Pathog Dis , vol.73
- Salata, C.¹ Baritussio, A.² Munegato, D.³ Calistri, A.⁴ Ha, H.R.⁵ Bigler, L.⁶ Fabris, F.⁷ Parolin, C.⁸ Palu, G.⁹ Mirazimi, A.¹⁰

16
- 84929505474
- Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates
- Thi EP, Mire CE, Lee AC, Geisbert JB, Zhou JZ, Agans KN, Snead NM, Deer DJ, Barnard TR, Fenton KA, MacLachlan I, Geisbert TW. 2015. Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates. Nature 521:362-365. http://dx.doi.org/10.1038/nature14442.
- (2015) Nature , vol.521 , pp. 362-365
- Thi, E.P.¹ Mire, C.E.² Lee, A.C.³ Geisbert, J.B.⁴ Zhou, J.Z.⁵ Agans, K.N.⁶ Snead, N.M.⁷ Deer, D.J.⁸ Barnard, T.R.⁹ Fenton, K.A.¹⁰ MacLachlan, I.¹¹ Geisbert, T.W.¹²

17
- 84899439262
- Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430
- Warren TK, Wells J, Panchal RG, Stuthman KS, Garza NL, Van Tongeren SA, Dong L, Retterer CJ, Eaton BP, Pegoraro G, Honnold S, Bantia S, Kotian P, Chen X, Taubenheim BR, Welch LS, Minning DM, Babu YS, Sheridan WP, Bavari S. 2014. Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430. Nature 508:402-405. http://dx.doi.org/10.1038/nature13027.
- (2014) Nature , vol.508 , pp. 402-405
- Warren, T.K.¹ Wells, J.² Panchal, R.G.³ Stuthman, K.S.⁴ Garza, N.L.⁵ Van Tongeren, S.A.⁶ Dong, L.⁷ Retterer, C.J.⁸ Eaton, B.P.⁹ Pegoraro, G.¹⁰ Honnold, S.¹¹ Bantia, S.¹² Kotian, P.¹³ Chen, X.¹⁴ Taubenheim, B.R.¹⁵ Welch, L.S.¹⁶ Minning, D.M.¹⁷ Babu, Y.S.¹⁸ Sheridan, W.P.¹⁹ Bavari, S.²⁰ more..

18
- 78149355646
- Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner
- Nanbo A, Imai M, Watanabe S, Noda T, Takahashi K, Neumann G, Halfmann P, Kawaoka Y. 2010. Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. PLoS Pathog 6:e1001121. http://dx.doi.org/10.1371/journal.ppat.1001121.
- (2010) PLoS Pathog , vol.6
- Nanbo, A.¹ Imai, M.² Watanabe, S.³ Noda, T.⁴ Takahashi, K.⁵ Neumann, G.⁶ Halfmann, P.⁷ Kawaoka, Y.⁸

19
- 78149301316
- Cellular entry of Ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes
- Saeed MF, Kolokoltsov AA, Albrecht T, Davey RA. 2010. Cellular entry of Ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes. PLoS Pathog 6:e1001110. http://dx.doi.org/10.1371/journal.ppat.1001110.
- (2010) PLoS Pathog , vol.6
- Saeed, M.F.¹ Kolokoltsov, A.A.² Albrecht, T.³ Davey, R.A.⁴

20
- 84953897258
- Ebolavirus glycoprotein directs fusion through NPC1+ endolysosomes
- Simmons JA, D'Souza RS, Ruas M, Galione A, Casanova JE, White JM. 2016. Ebolavirus glycoprotein directs fusion through NPC1+ endolysosomes. J Virol 90:605-610. http://dx.doi.org/10.1128/JVI.01828-15.
- (2016) J Virol , vol.90 , pp. 605-610
- Simmons, J.A.¹ D'Souza, R.S.² Ruas, M.³ Galione, A.⁴ Casanova, J.E.⁵ White, J.M.⁶

21
- 19144365133
- Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection
- Chandran K, Sullivan NJ, Felbor U, Whelan SP, Cunningham JM. 2005. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science 308:1643-1645. http://dx.doi.org/10.1126/science.1110656.
- (2005) Science , vol.308 , pp. 1643-1645
- Chandran, K.¹ Sullivan, N.J.² Felbor, U.³ Whelan, S.P.⁴ Cunningham, J.M.⁵

22
- 84856225495
- Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression
- Gnirss K, Kuhl A, Karsten C, Glowacka I, Bertram S, Kaup F, Hofmann H, Pohlmann S. 2012. Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression. Virology 424:3-10. http://dx.doi.org/10.1016/j.virol.2011.11.031.
- (2012) Virology , vol.424 , pp. 3-10
- Gnirss, K.¹ Kuhl, A.² Karsten, C.³ Glowacka, I.⁴ Bertram, S.⁵ Kaup, F.⁶ Hofmann, H.⁷ Pohlmann, S.⁸

23
- 84863230082
- Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences
- Misasi J, Chandran K, Yang JY, Considine B, Filone CM, Cote M, Sullivan N, Fabozzi G, Hensley L, Cunningham J. 2012. Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences. J Virol 86:3284-3292. http://dx.doi.org/10.1128/JVI.06346-11.
- (2012) J Virol , vol.86 , pp. 3284-3292
- Misasi, J.¹ Chandran, K.² Yang, J.Y.³ Considine, B.⁴ Filone, C.M.⁵ Cote, M.⁶ Sullivan, N.⁷ Fabozzi, G.⁸ Hensley, L.⁹ Cunningham, J.¹⁰

24
- 33645788357
- Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein
- Schornberg K, Matsuyama S, Kabsch K, Delos S, Bouton A, White J. 2006. Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein. J Virol 80:4174-4178. http://dx.doi.org/10.1128/JVI.80.8.4174-4178.2006.
- (2006) J Virol , vol.80 , pp. 4174-4178
- Schornberg, K.¹ Matsuyama, S.² Kabsch, K.³ Delos, S.⁴ Bouton, A.⁵ White, J.⁶

25
- 80052851832
- Ebola virus entry requires the cholesterol transporter Niemann-Pick C1
- Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. 2011. Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature 477:340-343. http://dx.doi.org/10.1038/nature10348.
- (2011) Nature , vol.477 , pp. 340-343
- Carette, J.E.¹ Raaben, M.² Wong, A.C.³ Herbert, A.S.⁴ Obernosterer, G.⁵ Mulherkar, N.⁶ Kuehne, A.I.⁷ Kranzusch, P.J.⁸ Griffin, A.M.⁹ Ruthel, G.¹⁰ Dal Cin, P.¹¹ Dye, J.M.¹² Whelan, S.P.¹³ Chandran, K.¹⁴ Brummelkamp, T.R.¹⁵

26
- 80052868218
- Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection
- Cote M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J. 2011. Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection. Nature 477:344-348. http://dx.doi.org/10.1038/nature10380.
- (2011) Nature , vol.477 , pp. 344-348
- Cote, M.¹ Misasi, J.² Ren, T.³ Bruchez, A.⁴ Lee, K.⁵ Filone, C.M.⁶ Hensley, L.⁷ Li, Q.⁸ Ory, D.⁹ Chandran, K.¹⁰ Cunningham, J.¹¹

27
- 0038387389
- Hit and lead generation: Beyond high-throughput screening
- Bleicher KH, Bohm HJ, Muller K, Alanine AI. 2003. Hit and lead generation: beyond high-throughput screening. Nat Rev Drug Discov 2:369-378. http://dx.doi.org/10.1038/nrd1086.
- (2003) Nat Rev Drug Discov , vol.2 , pp. 369-378
- Bleicher, K.H.¹ Bohm, H.J.² Muller, K.³ Alanine, A.I.⁴

28
- 79952131874
- Impact of high-throughput screening in biomedical research
- Macarron R, Banks MN, Bojanic D, Burns DJ, Cirovic DA, Garyantes T, Green DV, Hertzberg RP, Janzen WP, Paslay JW, Schopfer U, Sittampalam GS. 2011. Impact of high-throughput screening in biomedical research. Nat Rev Drug Discov 10:188-195. http://dx.doi.org/10.1038/nrd3368.
- (2011) Nat Rev Drug Discov , vol.10 , pp. 188-195
- Macarron, R.¹ Banks, M.N.² Bojanic, D.³ Burns, D.J.⁴ Cirovic, D.A.⁵ Garyantes, T.⁶ Green, D.V.⁷ Hertzberg, R.P.⁸ Janzen, W.P.⁹ Paslay, J.W.¹⁰ Schopfer, U.¹¹ Sittampalam, G.S.¹²

29
- 34548295338
- Origin and evolution of high throughput screening
- Pereira DA, Williams JA. 2007. Origin and evolution of high throughput screening. Br J Pharmacol 152:53-61. http://dx.doi.org/10.1038/sj.bjp.0707373.
- (2007) Br J Pharmacol , vol.152 , pp. 53-61
- Pereira, D.A.¹ Williams, J.A.²

30
- 64249117460
- Isolation of whole mononuclear cells from peripheral blood and cord blood
- Chapter 7:Unit 7.1
- Fuss IJ, Kanof ME, Smith PD, Zola H. 2009. Isolation of whole mononuclear cells from peripheral blood and cord blood. Curr Protoc Immunol Chapter 7:Unit 7.1. http://dx.doi.org/10.1002/0471142735.im0701s85.
- (2009) Curr Protoc Immunol
- Fuss, I.J.¹ Kanof, M.E.² Smith, P.D.³ Zola, H.⁴

31
- 84875813276
- Isolation and generation of human dendritic cells
- Chapter 7:Unit 7.32
- Nair S, Archer GE, Tedder TF. 2012. Isolation and generation of human dendritic cells. Curr Protoc Immunol Chapter 7:Unit 7.32. http://dx.doi.org/10.1002/0471142735.im0732s99.
- (2012) Curr Protoc Immunol
- Nair, S.¹ Archer, G.E.² Tedder, T.F.³

32
- 84899932651
- Virus nomenclature below the species level: A standardized nomenclature for filovirus strains and variants rescued from cDNA
- Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brauburger K, Rodney Brister J, Bukreyev AA, Cai Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Muhlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. 2014. Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA. Arch Virol 159:1229-1237. http://dx.doi.org/10.1007/s00705-013-1877-2.
- (2014) Arch Virol , vol.159 , pp. 1229-1237
- Kuhn, J.H.¹ Bao, Y.² Bavari, S.³ Becker, S.⁴ Bradfute, S.⁵ Brauburger, K.⁶ Rodney Brister, J.⁷ Bukreyev, A.A.⁸ Cai, Y.⁹ Chandran, K.¹⁰ Davey, R.A.¹¹ Dolnik, O.¹² Dye, J.M.¹³ Enterlein, S.¹⁴ Gonzalez, J.P.¹⁵ Formenty, P.¹⁶ Freiberg, A.N.¹⁷ Hensley, L.E.¹⁸ Hoenen, T.¹⁹ Honko, A.N.²⁰ more..

33
- 38449123733
- In vitro and in vivo characterization of recombinant Ebola viruses expressing enhanced green fluorescent protein
- Ebihara H, Theriault S, Neumann G, Alimonti JB, Geisbert JB, Hensley LE, Groseth A, Jones SM, Geisbert TW, Kawaoka Y, Feldmann H. 2007. In vitro and in vivo characterization of recombinant Ebola viruses expressing enhanced green fluorescent protein. J Infect Dis 196(Suppl 2):S313-S322. http://dx.doi.org/10.1086/520590.
- (2007) J Infect Dis , vol.196 , pp. S313-S322
- Ebihara, H.¹ Theriault, S.² Neumann, G.³ Alimonti, J.B.⁴ Geisbert, J.B.⁵ Hensley, L.E.⁶ Groseth, A.⁷ Jones, S.M.⁸ Geisbert, T.W.⁹ Kawaoka, Y.¹⁰ Feldmann, H.¹¹

34
- 0023787830
- Vesicular stomatitis virus M protein in the nuclei of infected cells
- Lyles DS, Puddington L, McCreedy BJ, Jr. 1988. Vesicular stomatitis virus M protein in the nuclei of infected cells. J Virol 62:4387-4392.
- (1988) J Virol , vol.62 , pp. 4387-4392
- Lyles, D.S.¹ Puddington, L.² McCreedy, B.J.³

35
- 79953280350
- High-throughput screening of viral entry inhibitors using pseudotyped virus
- Chapter 13:Unit 13B.3
- Basu A, Mills DM, Bowlin TL. 2010. High-throughput screening of viral entry inhibitors using pseudotyped virus. Curr Protoc Pharmacol Chapter 13:Unit 13B.3. http://dx.doi.org/10.1002/0471141755.ph13b03s51.
- (2010) Curr Protoc Pharmacol
- Basu, A.¹ Mills, D.M.² Bowlin, T.L.³

36
- 84930655650
- Why is Tanimoto index an appropriate choice for fingerprint-based similarity calculations?
- Bajusz D, Racz A, Heberger K. 2015. Why is Tanimoto index an appropriate choice for fingerprint-based similarity calculations? J Cheminform 7:20. http://dx.doi.org/10.1186/s13321-015-0069-3.
- (2015) J Cheminform , vol.7 , pp. 20
- Bajusz, D.¹ Racz, A.² Heberger, K.³

37
- 80054774353
- Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis
- Aleksandrowicz P, Marzi A, Biedenkopf N, Beimforde N, Becker S, Hoenen T, Feldmann H, Schnittler HJ. 2011. Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis. J Infect Dis 204(Suppl 3):S957-S967. http://dx.doi.org/10.1093/infdis/jir326.
- (2011) J Infect Dis , vol.204 , pp. S957-S967
- Aleksandrowicz, P.¹ Marzi, A.² Biedenkopf, N.³ Beimforde, N.⁴ Becker, S.⁵ Hoenen, T.⁶ Feldmann, H.⁷ Schnittler, H.J.⁸

38
- 0031449064
- A system for functional analysis of Ebola virus glycoprotein
- Takada A, Robison C, Goto H, Sanchez A, Murti KG, Whitt MA, Kawaoka Y. 1997. A system for functional analysis of Ebola virus glycoprotein. Proc Natl Acad Sci U S A 94:14764-14769. http://dx.doi.org/10.1073/pnas.94.26.14764.
- (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 14764-14769
- Takada, A.¹ Robison, C.² Goto, H.³ Sanchez, A.⁴ Murti, K.G.⁵ Whitt, M.A.⁶ Kawaoka, Y.⁷

39
- 84940172223
- Ebola vaccine. VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain
- Marzi A, Robertson SJ, Haddock E, Feldmann F, Hanley PW, Scott DP, Strong JE, Kobinger G, Best SM, Feldmann H. 2015. Ebola vaccine. VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain. Science 349:739-742. http://dx.doi.org/10.1126/science.aab3920.
- (2015) Science , vol.349 , pp. 739-742
- Marzi, A.¹ Robertson, S.J.² Haddock, E.³ Feldmann, F.⁴ Hanley, P.W.⁵ Scott, D.P.⁶ Strong, J.E.⁷ Kobinger, G.⁸ Best, S.M.⁹ Feldmann, H.¹⁰

40
- 84903458261
- Discovery of a novel compound with anti-Venezuelan equine encephalitis virus activity that targets the nonstructural protein 2
- Chung DH, Jonsson CB, Tower NA, Chu YK, Sahin E, Golden JE, Noah JW, Schroeder CE, Sotsky JB, Sosa MI, Cramer DE, McKellip SN, Rasmussen L, White EL, Schmaljohn CS, Julander JG, Smith JM, Filone CM, Connor JH, Sakurai Y, Davey RA. 2014. Discovery of a novel compound with anti-Venezuelan equine encephalitis virus activity that targets the nonstructural protein 2. PLoS Pathog 10:e1004213. http://dx.doi.org/10.1371/journal.ppat.1004213.
- (2014) PLoS Pathog , vol.10
- Chung, D.H.¹ Jonsson, C.B.² Tower, N.A.³ Chu, Y.K.⁴ Sahin, E.⁵ Golden, J.E.⁶ Noah, J.W.⁷ Schroeder, C.E.⁸ Sotsky, J.B.⁹ Sosa, M.I.¹⁰ Cramer, D.E.¹¹ McKellip, S.N.¹² Rasmussen, L.¹³ White, E.L.¹⁴ Schmaljohn, C.S.¹⁵ Julander, J.G.¹⁶ Smith, J.M.¹⁷ Filone, C.M.¹⁸ Connor, J.H.¹⁹ Sakurai, Y.²⁰ Davey, R.A.²¹ more..

41
- 84904560173
- Identification and characterization of small molecule human papillomavirus E6 inhibitors
- Malecka KA, Fera D, Schultz DC, Hodawadekar S, Reichman M, Donover PS, Murphy ME, Marmorstein R. 2014. Identification and characterization of small molecule human papillomavirus E6 inhibitors. ACS Chem Biol 9:1603-1612. http://dx.doi.org/10.1021/cb500229d.
- (2014) ACS Chem Biol , vol.9 , pp. 1603-1612
- Malecka, K.A.¹ Fera, D.² Schultz, D.C.³ Hodawadekar, S.⁴ Reichman, M.⁵ Donover, P.S.⁶ Murphy, M.E.⁷ Marmorstein, R.⁸

42
- 80053568739
- Current perspectives on the phylogeny of Filoviridae
- Barrette RW, Xu L, Rowland JM, McIntosh MT. 2011. Current perspectives on the phylogeny of Filoviridae. Infect Genet Evol 11:1514-1519. http://dx.doi.org/10.1016/j.meegid.2011.06.017.
- (2011) Infect Genet Evol , vol.11 , pp. 1514-1519
- Barrette, R.W.¹ Xu, L.² Rowland, J.M.³ McIntosh, M.T.⁴

43
- 33845792555
- CellProfiler: Image analysis software for identifying and quantifying cell phenotypes
- Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, Friman O, Guertin DA, Chang JH, Lindquist RA, Moffat J, Golland P, Sabatini DM. 2006. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 7:R100. http://dx.doi.org/10.1186/gb-2006-7-10-r100.
- (2006) Genome Biol , vol.7 , pp. R100
- Carpenter, A.E.¹ Jones, T.R.² Lamprecht, M.R.³ Clarke, C.⁴ Kang, I.H.⁵ Friman, O.⁶ Guertin, D.A.⁷ Chang, J.H.⁸ Lindquist, R.A.⁹ Moffat, J.¹⁰ Golland, P.¹¹ Sabatini, D.M.¹²

44
- 79954500285
- Improved structure, function and compatibility for CellProfiler: Modular high-throughput image analysis software
- Kamentsky L, Jones TR, Fraser A, Bray MA, Logan DJ, Madden KL, Ljosa V, Rueden C, Eliceiri KW, Carpenter AE. 2011. Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software. Bioinformatics 27:1179-1180. http://dx.doi.org/10.1093/bioinformatics/btr095.
- (2011) Bioinformatics , vol.27 , pp. 1179-1180
- Kamentsky, L.¹ Jones, T.R.² Fraser, A.³ Bray, M.A.⁴ Logan, D.J.⁵ Madden, K.L.⁶ Ljosa, V.⁷ Rueden, C.⁸ Eliceiri, K.W.⁹ Carpenter, A.E.¹⁰

45
- 77149129342
- Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling
- Koivusalo M, Welch C, Hayashi H, Scott CC, Kim M, Alexander T, Touret N, Hahn KM, Grinstein S. 2010. Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling. J Cell Biol 188:547-563. http://dx.doi.org/10.1083/jcb.200908086.
- (2010) J Cell Biol , vol.188 , pp. 547-563
- Koivusalo, M.¹ Welch, C.² Hayashi, H.³ Scott, C.C.⁴ Kim, M.⁵ Alexander, T.⁶ Touret, N.⁷ Hahn, K.M.⁸ Grinstein, S.⁹

46
- 63149192804
- The primed ebolavirus glycoprotein (19-kilodalton GP1,2): Sequence and residues critical for host cell binding
- Dube D, Brecher MB, Delos SE, Rose SC, Park EW, Schornberg KL, Kuhn JH, White JM. 2009. The primed ebolavirus glycoprotein (19-kilodalton GP1,2): sequence and residues critical for host cell binding. J Virol 83:2883-2891. http://dx.doi.org/10.1128/JVI.01956-08.
- (2009) J Virol , vol.83 , pp. 2883-2891
- Dube, D.¹ Brecher, M.B.² Delos, S.E.³ Rose, S.C.⁴ Park, E.W.⁵ Schornberg, K.L.⁶ Kuhn, J.H.⁷ White, J.M.⁸

47
- 84857668041
- Filovirus entry: A novelty in the viral fusion world
- Hunt CL, Lennemann NJ, Maury W. 2012. Filovirus entry: a novelty in the viral fusion world. Viruses 4:258-275. http://dx.doi.org/10.3390/v4020258.
- (2012) Viruses , vol.4 , pp. 258-275
- Hunt, C.L.¹ Lennemann, N.J.² Maury, W.³

48
- 79955542545
- Inhibition of Ebola virus entry by a C-peptide targeted to endosomes
- Miller EH, Harrison JS, Radoshitzky SR, Higgins CD, Chi X, Dong L, Kuhn JH, Bavari S, Lai JR, Chandran K. 2011. Inhibition of Ebola virus entry by a C-peptide targeted to endosomes. J Biol Chem 286:15854-15861. http://dx.doi.org/10.1074/jbc.M110.207084.
- (2011) J Biol Chem , vol.286 , pp. 15854-15861
- Miller, E.H.¹ Harrison, J.S.² Radoshitzky, S.R.³ Higgins, C.D.⁴ Chi, X.⁵ Dong, L.⁶ Kuhn, J.H.⁷ Bavari, S.⁸ Lai, J.R.⁹ Chandran, K.¹⁰

49
- 84943388053
- The endosomal-lysosomal system: From acidification and cargo sorting to neurodegeneration
- Hu YB, Dammer EB, Ren RJ, Wang G. 2015. The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration. Transl Neurodegener 4:18. http://dx.doi.org/10.1186/s40035-015-0041-1.
- (2015) Transl Neurodegener , vol.4 , pp. 18
- Hu, Y.B.¹ Dammer, E.B.² Ren, R.J.³ Wang, G.⁴

50
- 78651415502
- Ion flux and the function of endosomes and lysosomes: PH is just the start: The flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH
- Scott CC, Gruenberg J. 2011. Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH. Bioessays 33:103-110. http://dx.doi.org/10.1002/bies.201000108.
- (2011) Bioessays , vol.33 , pp. 103-110
- Scott, C.C.¹ Gruenberg, J.²

51
- 84880437007
- Serine protease EspP from enterohemorrhagic Escherichia coli is sufficient to induce Shiga toxin macropinocytosis in intestinal epithelium
- In J, Lukyanenko V, Foulke-Abel J, Hubbard AL, Delannoy M, Hansen AM, Kaper JB, Boisen N, Nataro JP, Zhu C, Boedeker EC, Giron JA, Kovbasnjuk O. 2013. Serine protease EspP from enterohemorrhagic Escherichia coli is sufficient to induce Shiga toxin macropinocytosis in intestinal epithelium. PLoS One 8:e69196. http://dx.doi.org/10.1371/journal.pone.0069196.
- (2013) PLoS One , vol.8
- In, J.¹ Lukyanenko, V.² Foulke-Abel, J.³ Hubbard, A.L.⁴ Delannoy, M.⁵ Hansen, A.M.⁶ Kaper, J.B.⁷ Boisen, N.⁸ Nataro, J.P.⁹ Zhu, C.¹⁰ Boedeker, E.C.¹¹ Giron, J.A.¹² Kovbasnjuk, O.¹³

52
- 58249112313
- Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis
- Malyukova I, Murray KF, Zhu C, Boedeker E, Kane A, Patterson K, Peterson JR, Donowitz M, Kovbasnjuk O. 2009. Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis. Am J Physiol Gastrointest Liver Physiol 296:G78-G92. http://dx.doi.org/10.1152/ajpgi.90347.2008.
- (2009) Am J Physiol Gastrointest Liver Physiol , vol.296 , pp. G78-G92
- Malyukova, I.¹ Murray, K.F.² Zhu, C.³ Boedeker, E.⁴ Kane, A.⁵ Patterson, K.⁶ Peterson, J.R.⁷ Donowitz, M.⁸ Kovbasnjuk, O.⁹

53
- 81155134753
- Understanding the mechanism of IL-1beta secretion
- Lopez-Castejon G, Brough D. 2011. Understanding the mechanism of IL-1beta secretion. Cytokine Growth Factor Rev 22:189-195. http://dx.doi.org/10.1016/j.cytogfr.2011.10.001.
- (2011) Cytokine Growth Factor Rev , vol.22 , pp. 189-195
- Lopez-Castejon, G.¹ Brough, D.²

54
- 84863767856
- Ebolavirus requires acid sphingomyelinase activity and plasma membrane sphingomyelin for infection
- Miller ME, Adhikary S, Kolokoltsov AA, Davey RA. 2012. Ebolavirus requires acid sphingomyelinase activity and plasma membrane sphingomyelin for infection. J Virol 86:7473-7483. http://dx.doi.org/10.1128/JVI.00136-12.
- (2012) J Virol , vol.86 , pp. 7473-7483
- Miller, M.E.¹ Adhikary, S.² Kolokoltsov, A.A.³ Davey, R.A.⁴

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