VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain

Science

Volumn 349, Issue 6249, 2015, Pages 739-742

  Marzi, Andrea ^a   Robertson, Shelly J ^a   Haddock, Elaine ^a   Feldmann, Friederike ^a   Hanley, Patrick W ^a   Scott, Dana P ^a   Strong, James E ^b   Kobinger, Gary ^b   Best, Sonja M ^a   Feldmann, Heinz ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b PUBLIC HEALTH AGENCY OF CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EBOLA VIRUS GLYCOPROTEIN; GAMMA INTERFERON; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 15; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIVER ENZYME; MARBURG VIRUS VACCINE; MONOCYTE CHEMOTACTIC PROTEIN; NEUTRALIZING ANTIBODY; PEGINTERFERON ALPHA; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS VACCINE; EBOLA VACCINE; GLYCOPROTEIN; VIRUS PROTEIN;

DISEASE VECTOR; EPIDEMIC; IMMUNITY; PRIMATE; PUBLIC HEALTH; VACCINATION; VIRAL DISEASE;

ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL EXAMINATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; EBOLA HEMORRHAGIC FEVER; ENZYME BLOOD LEVEL; EPIDEMIC; GENETIC VARIABILITY; GOLD STANDARD; HEALTH CARE PERSONNEL; IMMUNOGENICITY; INNATE IMMUNITY; LIMIT OF DETECTION; MACACA FASCICULARIS; MACAQUE MODEL; MACROPHAGE ACTIVATION; MARBURGVIRUS; NATURAL KILLER CELL; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); POST EXPOSURE PROPHYLAXIS; PRIORITY JOURNAL; SIERRA LEONE; SINGLE DRUG DOSE; VACCINATION; VESICULOVIRUS; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS STRAIN; WEST AFRICAN; ANIMAL; DRUG SCREENING; EBOLAVIRUS; GENE VECTOR; GENETICS; HEMORRHAGIC FEVER, EBOLA; IMMUNOLOGY; MACACA;

GUINEA; LIBERIA [WEST AFRICA]; SIERRA LEONE;

EBOLA VIRUS; MACACA; VESICULAR STOMATITIS VIRUS;

ANIMALS; DRUG EVALUATION, PRECLINICAL; EBOLA VACCINES; EBOLAVIRUS; GENETIC VECTORS; GLYCOPROTEINS; HEMORRHAGIC FEVER, EBOLA; MACACA; VESICULOVIRUS; VIRAL PROTEINS;

EID: 84940172223     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aab3920     Document Type: Article

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