-
1
-
-
84907263545
-
Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
-
Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti JB, Fausther-Bovendo H, Wei H, Aviles J, Hiatt E, Johnson A, Morton J, Swope K, Bohorov O, Bohorova N, Goodman C, Kim D, Pauly MH, Velasco J, Pettitt J, Olinger GG, Whaley K, Xu B, Strong JE, Zeitlin L, Kobinger GP. 2014. Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature 514:47-53. http://dx.doi.org/10.1038/nature13777.
-
(2014)
Nature
, vol.514
, pp. 47-53
-
-
Qiu, X.1
Wong, G.2
Audet, J.3
Bello, A.4
Fernando, L.5
Alimonti, J.B.6
Fausther-Bovendo, H.7
Wei, H.8
Aviles, J.9
Hiatt, E.10
Johnson, A.11
Morton, J.12
Swope, K.13
Bohorov, O.14
Bohorova, N.15
Goodman, C.16
Kim, D.17
Pauly, M.H.18
Velasco, J.19
Pettitt, J.20
Olinger, G.G.21
Whaley, K.22
Xu, B.23
Strong, J.E.24
Zeitlin, L.25
Kobinger, G.P.26
more..
-
2
-
-
84930456828
-
A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity
-
Johansen LM, Dewald LE, Shoemaker CJ, Hoffstrom BG, Lear-Rooney CM, Stossel A, Nelson E, Delos SE, Simmons JA, Grenier JM, Pierce LT, Pajouhesh H, Lehár J, Hensley LE, Glass PJ, White JM, Olinger GG. 2015. A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity. Sci Transl Med 7:290ra89. http://dx.doi.org/10.1126/scitranslmed.aaa5597.
-
(2015)
Sci Transl Med
, vol.7
-
-
Johansen, L.M.1
Dewald, L.E.2
Shoemaker, C.J.3
Hoffstrom, B.G.4
Lear-Rooney, C.M.5
Stossel, A.6
Nelson, E.7
Delos, S.E.8
Simmons, J.A.9
Grenier, J.M.10
Pierce, L.T.11
Pajouhesh, H.12
Lehár, J.13
Hensley, L.E.14
Glass, P.J.15
White, J.M.16
Olinger, G.G.17
-
3
-
-
80052851832
-
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1
-
Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. 2011. Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature 477: 340-343. http://dx.doi.org/10.1038/nature10348.
-
(2011)
Nature
, vol.477
, pp. 340-343
-
-
Carette, J.E.1
Raaben, M.2
Wong, A.C.3
Herbert, A.S.4
Obernosterer, G.5
Mulherkar, N.6
Kuehne, A.I.7
Kranzusch, P.J.8
Griffin, A.M.9
Ruthel, G.10
Dal Cin, P.11
Dye, J.M.12
Whelan, S.P.13
Chandran, K.14
Brummelkamp, T.R.15
-
4
-
-
80052868218
-
Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection
-
Côté M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J. 2011. Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection. Nature 477: 344-348. http://dx.doi.org/10.1038/nature10380.
-
(2011)
Nature
, vol.477
, pp. 344-348
-
-
Côté, M.1
Misasi, J.2
Ren, T.3
Bruchez, A.4
Lee, K.5
Filone, C.M.6
Hensley, L.7
Li, Q.8
Ory, D.9
Chandran, K.10
Cunningham, J.11
-
5
-
-
84863999291
-
Chinese hamster ovary cell lines selected for resistance to ebolavirus glycoprotein mediated infection are defective for NPC1 expression
-
Haines KM, Vande Burgt NH, Francica JR, Kaletsky RL, Bates P. 2012. Chinese hamster ovary cell lines selected for resistance to ebolavirus glycoprotein mediated infection are defective for NPC1 expression. Virology 432:20-28. http://dx.doi.org/10.1016/j.virol.2012.05.018.
-
(2012)
Virology
, vol.432
, pp. 20-28
-
-
Haines, K.M.1
Vande Burgt, N.H.2
Francica, J.R.3
Kaletsky, R.L.4
Bates, P.5
-
6
-
-
84859907529
-
Ebola virus entry requires the host-programmed recognition of an intracellular receptor
-
Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, Chandran K. 2012. Ebola virus entry requires the host-programmed recognition of an intracellular receptor. EMBO J 31:1947-1960. http://dx.doi.org/10.1038/emboj.2012.53.
-
(2012)
EMBO J
, vol.31
, pp. 1947-1960
-
-
Miller, E.H.1
Obernosterer, G.2
Raaben, M.3
Herbert, A.S.4
Deffieu, M.S.5
Krishnan, A.6
Ndungo, E.7
Sandesara, R.G.8
Carette, J.E.9
Kuehne, A.I.10
Ruthel, G.11
Pfeffer, S.R.12
Dye, J.M.13
Whelan, S.P.14
Brummelkamp, T.R.15
Chandran, K.16
-
7
-
-
84929486001
-
Ebola virus entry: a curious and complex series of events
-
Moller-Tank S, Maury W. 2015. Ebola virus entry: a curious and complex series of events. PLoS Pathog 11:e1004731. http://dx.doi.org/10.1371/journal.ppat.1004731.
-
(2015)
PLoS Pathog
, vol.11
-
-
Moller-Tank, S.1
Maury, W.2
-
8
-
-
84859897771
-
Anew player in the puzzle of filovirus entry
-
White JM, Schornberg KL. 2012.Anew player in the puzzle of filovirus entry. Nat Rev Microbiol 10:317-322. http://dx.doi.org/10.1038/nrmicro2764.
-
(2012)
Nat Rev Microbiol
, vol.10
, pp. 317-322
-
-
White, J.M.1
Schornberg, K.L.2
-
9
-
-
84923050027
-
Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining step
-
Mingo RM, Simmons JA, Shoemaker CJ, Nelson EA, Schornberg KL, D'Souza RS, Casanova JE, White JM. 2015. Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining step. J Virol 89:2931-2943. http://dx.doi.org/10.1128/JVI.03398-14.
-
(2015)
J Virol
, vol.89
, pp. 2931-2943
-
-
Mingo, R.M.1
Simmons, J.A.2
Shoemaker, C.J.3
Nelson, E.A.4
Schornberg, K.L.5
D'Souza, R.S.6
Casanova, J.E.7
White, J.M.8
-
10
-
-
84923815384
-
Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment
-
Sakurai Y, Kolokoltsov AA, Chen C-C, Tidwell MW, Bauta WE, Klugbauer N, Grimm C, Wahl-Schott C, Biel M, Davey RA. 2015. Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment. Science 347:995-998. http://dx.doi.org/10.1126/science.1258758.
-
(2015)
Science
, vol.347
, pp. 995-998
-
-
Sakurai, Y.1
Kolokoltsov, A.A.2
Chen, C.-C.3
Tidwell, M.W.4
Bauta, W.E.5
Klugbauer, N.6
Grimm, C.7
Wahl-Schott, C.8
Biel, M.9
Davey, R.A.10
-
11
-
-
84923886278
-
Virology delineating Ebola entry
-
Falzarano D, Feldmann H. 2015. Virology delineating Ebola entry. Science 347:947-948. http://dx.doi.org/10.1126/science.aaa8121.
-
(2015)
Science
, vol.347
, pp. 947-948
-
-
Falzarano, D.1
Feldmann, H.2
-
12
-
-
84877119843
-
Anionic lipids are required for vesicular stomatitis virus G proteinmediated single particle fusion with supported lipid bilayers
-
Matos PM, Marin M, Ahn B, Lam W, Santos NC, Melikyan GB. 2013. Anionic lipids are required for vesicular stomatitis virus G proteinmediated single particle fusion with supported lipid bilayers. J Biol Chem 288:12416-12425. http://dx.doi.org/10.1074/jbc. M113.462028.
-
(2013)
J Biol Chem
, vol.288
, pp. 12416-12425
-
-
Matos, P.M.1
Marin, M.2
Ahn, B.3
Lam, W.4
Santos, N.C.5
Melikyan, G.B.6
-
13
-
-
82655186589
-
Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion
-
de la Vega, M, Marin M, Kondo N, Miyauchi K, Kim Y, Epand RF, Epand RM, Melikyan GB. 2011. Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion. Retrovirology 8:99. http://dx.doi.org/10.1186/1742-4690-8-99.
-
(2011)
Retrovirology
, vol.8
, pp. 99
-
-
de la Vega, M.1
Marin, M.2
Kondo, N.3
Miyauchi, K.4
Kim, Y.5
Epand, R.F.6
Epand, R.M.7
Melikyan, G.B.8
-
14
-
-
33645788357
-
Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein
-
Schornberg K, Matsuyama S, Kabsch K, Delos S, Bouton A, White J. 2006. Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein. J Virol 80:4174-4178. http://dx.doi.org/10.1128/JVI.80.8.4174-4178.2006.
-
(2006)
J Virol
, vol.80
, pp. 4174-4178
-
-
Schornberg, K.1
Matsuyama, S.2
Kabsch, K.3
Delos, S.4
Bouton, A.5
White, J.6
-
15
-
-
19144365133
-
Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection
-
Chandran K, Sullivan NJ, Felbor U, Whelan SP, Cunningham JM. 2005. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science 308:1643-1645. http://dx.doi.org/10.1126/science.1110656.
-
(2005)
Science
, vol.308
, pp. 1643-1645
-
-
Chandran, K.1
Sullivan, N.J.2
Felbor, U.3
Whelan, S.P.4
Cunningham, J.M.5
-
16
-
-
84901350351
-
Ebolavirus entry requires a compact hydrophobic fist at the tip of the fusion loop
-
Gregory SM, Larsson P, Nelson EA, Kasson PM, White JM, Tamm LK. 2014. Ebolavirus entry requires a compact hydrophobic fist at the tip of the fusion loop. J Virol 88:6636-6649. http://dx.doi.org/10.1128/JVI.00396-14.
-
(2014)
J Virol
, vol.88
, pp. 6636-6649
-
-
Gregory, S.M.1
Larsson, P.2
Nelson, E.A.3
Kasson, P.M.4
White, J.M.5
Tamm, L.K.6
-
17
-
-
78149301316
-
Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes
-
Saeed MF, Kolokoltsov AA, Albrecht T, Davey RA. 2010. Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes. PLoS Pathog 6:e1001110. http://dx.doi.org/10.1371/journal.ppat.1001110.
-
(2010)
PLoS Pathog
, vol.6
-
-
Saeed, M.F.1
Kolokoltsov, A.A.2
Albrecht, T.3
Davey, R.A.4
-
18
-
-
77957661740
-
A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating
-
Mire CE, White JM, Whitt MA. 2010. A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating. PLoS Pathog 6:e1000994. http://dx.doi.org/10.1371/journal.ppat.1000994.
-
(2010)
PLoS Pathog
, vol.6
-
-
Mire, C.E.1
White, J.M.2
Whitt, M.A.3
-
19
-
-
58149390171
-
Host cell factors and functions involved in vesicular stomatitis virus entry
-
Johannsdottir HK, Mancini R, Kartenbeck J, Amato L, Helenius A. 2009. Host cell factors and functions involved in vesicular stomatitis virus entry. J Virol 83:440-453. http://dx.doi.org/10.1128/JVI.01864-08.
-
(2009)
J Virol
, vol.83
, pp. 440-453
-
-
Johannsdottir, H.K.1
Mancini, R.2
Kartenbeck, J.3
Amato, L.4
Helenius, A.5
-
20
-
-
84859514186
-
Filovirus entry into cells-new insights
-
Miller EH, Chandran K. 2012. Filovirus entry into cells-new insights. Curr Opin Virol 2:206-214. http://dx.doi.org/10.1016/j.coviro.2012.02.015.
-
(2012)
Curr Opin Virol
, vol.2
, pp. 206-214
-
-
Miller, E.H.1
Chandran, K.2
-
21
-
-
67349287016
-
NAADP mobilizes calcium from acidic organelles through two-pore channels
-
Calcraft PJ, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, Tang J, Rietdorf K, Teboul L, Chuang K-T, Lin P, Xiao R, Wang C, Zhu Y, Lin Y, Wyatt CN, Parrington J, Ma J, Evans AM, Galione A, Zhu MX. 2009. NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature 459:596-600. http://dx.doi.org/10.1038/nature08030.
-
(2009)
Nature
, vol.459
, pp. 596-600
-
-
Calcraft, P.J.1
Ruas, M.2
Pan, Z.3
Cheng, X.4
Arredouani, A.5
Hao, X.6
Tang, J.7
Rietdorf, K.8
Teboul, L.9
Chuang, K.-T.10
Lin, P.11
Xiao, R.12
Wang, C.13
Zhu, Y.14
Lin, Y.15
Wyatt, C.N.16
Parrington, J.17
Ma, J.18
Evans, A.M.19
Galione, A.20
Zhu, M.X.21
more..
-
22
-
-
80054828843
-
Two-pore channels form homo-and heterodimers
-
Rietdorf K, Funnell TM, Ruas M, Heinemann J, Parrington J, Galione A. 2011. Two-pore channels form homo-and heterodimers. J Biol Chem 286:37058-37062. http://dx.doi.org/10.1074/jbc. C111.289835.
-
(2011)
J Biol Chem
, vol.286
, pp. 37058-37062
-
-
Rietdorf, K.1
Funnell, T.M.2
Ruas, M.3
Heinemann, J.4
Parrington, J.5
Galione, A.6
-
23
-
-
84874105202
-
mTOR regulates lysosomal ATPsensitive two-pore Na(+) channels to adapt to metabolic state
-
Cang C, Zhou Y, Navarro B, Seo Y-J, Aranda K, Shi L, Battaglia-Hsu S, Nissim I, Clapham DE, Ren D. 2013. mTOR regulates lysosomal ATPsensitive two-pore Na(+) channels to adapt to metabolic state. Cell 152: 778-790. http://dx.doi.org/10.1016/j.cell.2013.01.023.
-
(2013)
Cell
, vol.152
, pp. 778-790
-
-
Cang, C.1
Zhou, Y.2
Navarro, B.3
Seo, Y.-J.4
Aranda, K.5
Shi, L.6
Battaglia-Hsu, S.7
Nissim, I.8
Clapham, D.E.9
Ren, D.10
-
24
-
-
84883382591
-
Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L
-
van der Kant R, Fish A, Janssen L, Janssen H, Krom S, Ho N, Brummelkamp T, Carette J, Rocha N, Neefjes J. 2013. Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L. J Cell Sci 126:3462-3474. http://dx.doi.org/10.1242/jcs.129270.
-
(2013)
J Cell Sci
, vol.126
, pp. 3462-3474
-
-
van der Kant, R.1
Fish, A.2
Janssen, L.3
Janssen, H.4
Krom, S.5
Ho, N.6
Brummelkamp, T.7
Carette, J.8
Rocha, N.9
Neefjes, J.10
-
25
-
-
0034028669
-
Lysosome-endosome fusion and lysosome biogenesis
-
Luzio JP, Rous BA, Bright NA, Pryor PR, Mullock BM, Piper RC. 2000. Lysosome-endosome fusion and lysosome biogenesis. J Cell Sci 113:1515-1524.
-
(2000)
J Cell Sci
, vol.113
, pp. 1515-1524
-
-
Luzio, J.P.1
Rous, B.A.2
Bright, N.A.3
Pryor, P.R.4
Mullock, B.M.5
Piper, R.C.6
-
26
-
-
84947753845
-
Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion
-
Cao Q, Zhong XZ, Zou Y, Murrell-Lagnado R, Zhu MX, Dong X-P. 2015. Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion. The J Cell Biol 209:879-894. http://dx.doi.org/10.1083/jcb.201409071.
-
(2015)
The J Cell Biol
, vol.209
, pp. 879-894
-
-
Cao, Q.1
Zhong, X.Z.2
Zou, Y.3
Murrell-Lagnado, R.4
Zhu, M.X.5
Dong, X.-P.6
-
27
-
-
84939778375
-
The phosphoinositide-gated lysosomal Ca(2+) channel, TRPML1, is required for phagosome maturation
-
Dayam RM, Saric A, Shilliday RE, Botelho RJ. 2015. The phosphoinositide-gated lysosomal Ca(2+) channel, TRPML1, is required for phagosome maturation. Traffic 16:1010-1026. http://dx.doi.org/10.1111/tra.12303.
-
(2015)
Traffic
, vol.16
, pp. 1010-1026
-
-
Dayam, R.M.1
Saric, A.2
Shilliday, R.E.3
Botelho, R.J.4
-
28
-
-
84962937031
-
Advanced methods of microscope control using μManager software
-
Edelstein AD, Tsuchida MA, Amodaj N, Pinkard H, Vale RD, Stuurman N. 2014. Advanced methods of microscope control using μManager software. J Biol Methods 1:e10.
-
(2014)
J Biol Methods
, vol.1
-
-
Edelstein, A.D.1
Tsuchida, M.A.2
Amodaj, N.3
Pinkard, H.4
Vale, R.D.5
Stuurman, N.6
-
29
-
-
80053347745
-
Interactive, computer-assisted tracking of speckle trajectories in fluorescence microscopy: application to actin polymerization and membrane fusion
-
Smith MB, Karatekin E, Gohlke A, Mizuno H, Watanabe N, Vavylonis D. 2011. Interactive, computer-assisted tracking of speckle trajectories in fluorescence microscopy: application to actin polymerization and membrane fusion. Biophys J 101:1794-1804. http://dx.doi.org/10.1016/j.bpj.2011.09.007.
-
(2011)
Biophys J
, vol.101
, pp. 1794-1804
-
-
Smith, M.B.1
Karatekin, E.2
Gohlke, A.3
Mizuno, H.4
Watanabe, N.5
Vavylonis, D.6
|