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Volumn 1435, Issue , 2016, Pages

A brief review of West Nile virus biology

Author keywords

Flavivirus; Virus immune evasion; West Nile virus; WNV protein; WNV structure

Indexed keywords

IMMUNE RESPONSE; NONHUMAN; PROTEIN FUNCTION; VIROLOGY; VIRUS ENVELOPE; VIRUS GENOME; VIRUS MORPHOLOGY; VIRUS NUCLEOCAPSID; VIRUS REPLICATION; WEST NILE VIRUS; ANIMAL; CULEX; HUMAN; IMMUNOLOGY; INSECT VECTOR; PHYSIOLOGY; TRANSMISSION; WEST NILE FEVER;

EID: 84979248020     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-3670-0_1     Document Type: Chapter
Times cited : (21)

References (95)
  • 1
    • 77955980756 scopus 로고    scopus 로고
    • West Nile virus and its emergence in the United States of America
    • Pubmed Central PMCID: 2913730
    • Murray KO, Mertens E, Despres P (2010) West Nile virus and its emergence in the United States of America. Vet Res 41(6):67, Pubmed Central PMCID: 2913730
    • (2010) Vet Res , vol.41 , Issue.6 , pp. 67
    • Murray, K.O.1    Mertens, E.2    Despres, P.3
  • 2
    • 84944256695 scopus 로고    scopus 로고
    • Factors that influence the transmission of West Nile virus in Florida
    • Day JF, Tabachnick WJ, Smartt CT (2015) Factors that influence the transmission of West Nile virus in Florida. J Med Entomol 52(5):743–754
    • (2015) J Med Entomol , vol.52 , Issue.5 , pp. 743-754
    • Day, J.F.1    Tabachnick, W.J.2    Smartt, C.T.3
  • 4
    • 84908177059 scopus 로고    scopus 로고
    • Regulation of flavivirus RNA synthesis and replication
    • Pubmed Central PMCID: 4295515
    • Selisko B, Wang C, Harris E, Canard B (2014) Regulation of flavivirus RNA synthesis and replication. Curr Opin Virol 9:74–83, Pubmed Central PMCID: 4295515
    • (2014) Curr Opin Virol , vol.9 , pp. 74-83
    • Selisko, B.1    Wang, C.2    Harris, E.3    Canard, B.4
  • 5
    • 84905902848 scopus 로고    scopus 로고
    • Flaviviral RNAs: Weapons and targets in the war between virus and host
    • Bidet K, Garcia-Blanco MA (2014) Flaviviral RNAs: weapons and targets in the war between virus and host. Biochem J 462(2):215–230
    • (2014) Biochem J , vol.462 , Issue.2 , pp. 215-230
    • Bidet, K.1    Garcia-Blanco, M.A.2
  • 6
    • 79952140351 scopus 로고    scopus 로고
    • Flavivirus cell entry and membrane fusion
    • Pubmed Central PMCID: 3206597
    • Smit JM, Moesker B, Rodenhuis-Zybert I, Wilschut J (2011) Flavivirus cell entry and membrane fusion. Viruses 3(2):160–171, Pubmed Central PMCID: 3206597
    • (2011) Viruses , vol.3 , Issue.2 , pp. 160-171
    • Smit, J.M.1    Moesker, B.2    Rodenhuis-Zybert, I.3    Wilschut, J.4
  • 7
    • 84855225539 scopus 로고    scopus 로고
    • Molecular mechanisms of flavivirus membrane fusion
    • Stiasny K, Fritz R, Pangerl K, Heinz FX (2011) Molecular mechanisms of flavivirus membrane fusion. Amino Acids 41(5):1159–1163
    • (2011) Amino Acids , vol.41 , Issue.5 , pp. 1159-1163
    • Stiasny, K.1    Fritz, R.2    Pangerl, K.3    Heinz, F.X.4
  • 8
    • 84941094331 scopus 로고    scopus 로고
    • Flaviviral replication complex: Coordination between RNA synthesis and 51-RNA capping
    • Klema VJ, Padmanabhan R, Choi KH (2015) Flaviviral replication complex: coordination between RNA synthesis and 51-RNA capping. Viruses 7(8):4640–4656
    • (2015) Viruses , vol.7 , Issue.8 , pp. 4640-4656
    • Klema, V.J.1    Padmanabhan, R.2    Choi, K.H.3
  • 9
    • 1542723492 scopus 로고    scopus 로고
    • Solution structure of dengue virus capsid protein reveals another fold
    • Pubmed Central PMCID: 373476
    • Ma L, Jones CT, Groesch TD, Kuhn RJ, Post CB (2004) Solution structure of dengue virus capsid protein reveals another fold. Proc Natl Acad Sci U S A 101(10):3414–3419, Pubmed Central PMCID: 373476
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.10 , pp. 3414-3419
    • Ma, L.1    Jones, C.T.2    Groesch, T.D.3    Kuhn, R.J.4    Post, C.B.5
  • 10
    • 0242574743 scopus 로고    scopus 로고
    • Visualization of membrane protein domains by cryo-electron microscopy of dengue virus
    • Pubmed Central PMCID: 4148076
    • Zhang W, Chipman PR, Corver J, Johnson PR, Zhang Y, Mukhopadhyay S et al (2003) Visualization of membrane protein domains by cryo-electron microscopy of dengue virus. Nat Struct Biol 10(11):907–912, Pubmed Central PMCID: 4148076
    • (2003) Nat Struct Biol , vol.10 , Issue.11 , pp. 907-912
    • Zhang, W.1    Chipman, P.R.2    Corver, J.3    Johnson, P.R.4    Zhang, Y.5    Mukhopadhyay, S.6
  • 12
    • 33748669852 scopus 로고    scopus 로고
    • West Nile virus 5’-cap structure is formed by sequential guanine N-7 and ribose 2’-O methylations by nonstructural protein 5
    • Pubmed Central PMCID: 1563844
    • Ray D, Shah A, Tilgner M, Guo Y, Zhao Y, Dong H et al (2006) West Nile virus 5’-cap structure is formed by sequential guanine N-7 and ribose 2’-O methylations by nonstructural protein 5. J Virol 80(17):8362–8370, Pubmed Central PMCID: 1563844
    • (2006) J Virol , vol.80 , Issue.17 , pp. 8362-8370
    • Ray, D.1    Shah, A.2    Tilgner, M.3    Guo, Y.4    Zhao, Y.5    Dong, H.6
  • 13
    • 0019418822 scopus 로고
    • Terminal sequences of the genome and replicative-from RNA of the flavivirus West Nile virus: Absence of poly(A) and possible role in RNA replication
    • Wengler G, Wengler G (1981) Terminal sequences of the genome and replicative-from RNA of the flavivirus West Nile virus: absence of poly(A) and possible role in RNA replication. Virology 113(2):544–555
    • (1981) Virology , vol.113 , Issue.2 , pp. 544-555
    • Wengler, G.1    Wengler, G.2
  • 14
    • 0035880277 scopus 로고    scopus 로고
    • The 3’ stem loop of the West Nile virus genomic RNA can suppress translation of chimeric mRNAs
    • Li W, Brinton MA (2001) The 3’ stem loop of the West Nile virus genomic RNA can suppress translation of chimeric mRNAs. Virology 287(1):49–61
    • (2001) Virology , vol.287 , Issue.1 , pp. 49-61
    • Li, W.1    Brinton, M.A.2
  • 15
    • 1542781698 scopus 로고    scopus 로고
    • 5’- and 3’-noncoding regions in flavivirus RNA
    • Markoff L (2003) 5’- and 3’-noncoding regions in flavivirus RNA. Adv Virus Res 59:177–228
    • (2003) Adv Virus Res , vol.59 , pp. 177-228
    • Markoff, L.1
  • 16
    • 40649100035 scopus 로고    scopus 로고
    • West Nile virus genome cyclization and RNA replication require two pairs of longdistance RNA interactions
    • Zhang B, Dong H, Stein DA, Iversen PL, Shi PY (2008) West Nile virus genome cyclization and RNA replication require two pairs of longdistance RNA interactions. Virology 373(1):1–13
    • (2008) Virology , vol.373 , Issue.1 , pp. 1-13
    • Zhang, B.1    Dong, H.2    Stein, D.A.3    Iversen, P.L.4    Shi, P.Y.5
  • 17
    • 34247564968 scopus 로고    scopus 로고
    • Distinct RNA elements confer specificity to flavivirus RNA cap methylation events
    • Pubmed Central PMCID: 1900168
    • Dong H, Ray D, Ren S, Zhang B, Puig- Basagoiti F, Takagi Y et al (2007) Distinct RNA elements confer specificity to flavivirus RNA cap methylation events. J Virol 81(9):4412–4421, Pubmed Central PMCID: 1900168
    • (2007) J Virol , vol.81 , Issue.9 , pp. 4412-4421
    • Dong, H.1    Ray, D.2    Ren, S.3    Zhang, B.4    Puig-Basagoiti, F.5    Takagi, Y.6
  • 18
    • 84891441339 scopus 로고    scopus 로고
    • Replication cycle and molecular biology of the West Nile virus
    • Pubmed Central PMCID: 3917430
    • Brinton MA (2014) Replication cycle and molecular biology of the West Nile virus. Viruses 6(1):13–53, Pubmed Central PMCID: 3917430
    • (2014) Viruses , vol.6 , Issue.1 , pp. 13-53
    • Brinton, M.A.1
  • 19
    • 0022472318 scopus 로고
    • The 3’-nucleotides of flavivirus genomic RNA form a conserved secondary structure
    • Brinton MA, Fernandez AV, Dispoto JH (1986) The 3’-nucleotides of flavivirus genomic RNA form a conserved secondary structure. Virology 153(1):113–121
    • (1986) Virology , vol.153 , Issue.1 , pp. 113-121
    • Brinton, M.A.1    Fernandez, A.V.2    Dispoto, J.H.3
  • 20
    • 84870836254 scopus 로고    scopus 로고
    • West Nile virus: A re-emerging pathogen revisited
    • Pubmed Central PMCID: 3782267
    • Martin-Acebes MA, Saiz JC (2012) West Nile virus: a re-emerging pathogen revisited. World J Virol 1(2):51–70, Pubmed Central PMCID: 3782267
    • (2012) World J Virol , vol.1 , Issue.2 , pp. 51-70
    • Martin-Acebes, M.A.1    Saiz, J.C.2
  • 21
    • 35348822495 scopus 로고    scopus 로고
    • Interaction between the cellular protein eEF1A and the 3’-terminal stem-loop of West Nile virus genomic RNA facilitates viral minus-strand RNA synthesis
    • Pubmed Central PMCID: 2045417
    • Davis WG, Blackwell JL, Shi PY, Brinton MA (2007) Interaction between the cellular protein eEF1A and the 3’-terminal stem-loop of West Nile virus genomic RNA facilitates viral minus-strand RNA synthesis. J Virol 81(18):10172–10187, Pubmed Central PMCID: 2045417
    • (2007) J Virol , vol.81 , Issue.18 , pp. 10172-10187
    • Davis, W.G.1    Blackwell, J.L.2    Shi, P.Y.3    Brinton, M.A.4
  • 22
    • 9444225980 scopus 로고    scopus 로고
    • Cell proteins bind specifically to West Nile virus minusstrand 3’ stem-loop RNA
    • Pubmed Central PMCID: 190653
    • Shi PY, Li W, Brinton MA (1996) Cell proteins bind specifically to West Nile virus minusstrand 3’ stem-loop RNA. J Virol 70(9):6278–6287, Pubmed Central PMCID: 190653
    • (1996) J Virol , vol.70 , Issue.9 , pp. 6278-6287
    • Shi, P.Y.1    Li, W.2    Brinton, M.A.3
  • 23
    • 59749084360 scopus 로고    scopus 로고
    • Genome cyclization as strategy for flavivirus RNA replication
    • Villordo SM, Gamarnik AV (2009) Genome cyclization as strategy for flavivirus RNA replication. Virus Res 139(2):230–239
    • (2009) Virus Res , vol.139 , Issue.2 , pp. 230-239
    • Villordo, S.M.1    Gamarnik, A.V.2
  • 24
    • 78649681550 scopus 로고    scopus 로고
    • A balance between circular and linear forms of the dengue virus genome is crucial for viral replication
    • Pubmed Central PMCID: 2995394
    • Villordo SM, Alvarez DE, Gamarnik AV (2010) A balance between circular and linear forms of the dengue virus genome is crucial for viral replication. RNA 16(12):2325–2335, Pubmed Central PMCID: 2995394
    • (2010) RNA , vol.16 , Issue.12 , pp. 2325-2335
    • Villordo, S.M.1    Alvarez, D.E.2    Gamarnik, A.V.3
  • 25
    • 79954474930 scopus 로고    scopus 로고
    • Dynamic RNA structures in the dengue virus genome
    • Iglesias NG, Gamarnik AV (2011) Dynamic RNA structures in the dengue virus genome. RNA Biol 8(2):249–257
    • (2011) RNA Biol , vol.8 , Issue.2 , pp. 249-257
    • Iglesias, N.G.1    Gamarnik, A.V.2
  • 26
    • 0036407156 scopus 로고    scopus 로고
    • The molecular biology of West Nile virus: A new invader of the western hemisphere
    • Brinton MA (2002) The molecular biology of West Nile virus: a new invader of the western hemisphere. Annu Rev Microbiol 56:371–402
    • (2002) Annu Rev Microbiol , vol.56 , pp. 371-402
    • Brinton, M.A.1
  • 27
    • 0024592786 scopus 로고
    • Analyses of the terminal sequences of West Nile virus structural proteins and of the in vitro translation of these proteins allow the proposal of a complete scheme of the proteolytic cleavages involved in their synthesis
    • Nowak T, Farber PM, Wengler G, Wengler G (1989) Analyses of the terminal sequences of West Nile virus structural proteins and of the in vitro translation of these proteins allow the proposal of a complete scheme of the proteolytic cleavages involved in their synthesis. Virology 169(2):365–376
    • (1989) Virology , vol.169 , Issue.2 , pp. 365-376
    • Nowak, T.1    Farber, P.M.2    Wengler, G.3    Wengler, G.4
  • 28
    • 0027264853 scopus 로고
    • Flavivirus premembrane protein cleavage and spike heterodimer secretion require the function of the viral proteinase NS3
    • Lobigs M (1993) Flavivirus premembrane protein cleavage and spike heterodimer secretion require the function of the viral proteinase NS3. Proc Natl Acad Sci U S A 90(13):6218–6222
    • (1993) Proc Natl Acad Sci U S A , vol.90 , Issue.13 , pp. 6218-6222
    • Lobigs, M.1
  • 29
    • 34249792118 scopus 로고    scopus 로고
    • Structure of immature West Nile virus
    • Pubmed Central PMCID: 1900247
    • Zhang Y, Kaufmann B, Chipman PR, Kuhn RJ, Rossmann MG (2007) Structure of immature West Nile virus. J Virol 81(11):6141-6145, Pubmed Central PMCID: 1900247
    • (2007) J Virol , vol.81 , Issue.11 , pp. 6141-6145
    • Zhang, Y.1    Kaufmann, B.2    Chipman, P.R.3    Kuhn, R.J.4    Rossmann, M.G.5
  • 30
    • 0035265843 scopus 로고    scopus 로고
    • Molecular organization of a recombinant subviral particle from tick-borne encephalitis virus
    • Ferlenghi I, Clarke M, Ruttan T, Allison SL, Schalich J, Heinz FX et al (2001) Molecular organization of a recombinant subviral particle from tick-borne encephalitis virus. Mol Cell 7(3):593–602
    • (2001) Mol Cell , vol.7 , Issue.3 , pp. 593-602
    • Ferlenghi, I.1    Clarke, M.2    Ruttan, T.3    Allison, S.L.4    Schalich, J.5    Heinz, F.X.6
  • 31
    • 0029684652 scopus 로고    scopus 로고
    • RNA binding properties of core protein of the flavivirus Kunjin
    • Khromykh AA, Westaway EG (1996) RNA binding properties of core protein of the flavivirus Kunjin. Arch Virol 141(3-4):685–699
    • (1996) Arch Virol , vol.141 , Issue.3-4 , pp. 685-699
    • Khromykh, A.A.1    Westaway, E.G.2
  • 32
    • 0026094713 scopus 로고
    • The flavivirus envelope protein E: Isolation of a soluble form from tick- borne encephalitis virus and its crystallization
    • Pubmed Central PMCID: 249068
    • Heinz FX, Mandl CW, Holzmann H, Kunz C, Harris BA, Rey F et al (1991) The flavivirus envelope protein E: isolation of a soluble form from tick- borne encephalitis virus and its crystallization. J Virol 65(10):5579–5583, Pubmed Central PMCID: 249068
    • (1991) J Virol , vol.65 , Issue.10 , pp. 5579-5583
    • Heinz, F.X.1    Mandl, C.W.2    Holzmann, H.3    Kunz, C.4    Harris, B.A.5    Rey, F.6
  • 33
    • 0024548815 scopus 로고
    • Antigenic structure of the flavivirus envelope protein E at the molecular level, using tick-borne encephalitis virus as a model
    • Pubmed Central PMCID: 247724
    • Mandl CW, Guirakhoo F, Holzmann H, Heinz FX, Kunz C (1989) Antigenic structure of the flavivirus envelope protein E at the molecular level, using tick-borne encephalitis virus as a model. J Virol 63(2):564–571, Pubmed Central PMCID: 247724
    • (1989) J Virol , vol.63 , Issue.2 , pp. 564-571
    • Mandl, C.W.1    Guirakhoo, F.2    Holzmann, H.3    Heinz, F.X.4    Kunz, C.5
  • 35
    • 20744441654 scopus 로고    scopus 로고
    • Envelope protein glycosylation status influences mouse neuroinvasion phenotype of genetic lineage 1 West Nile virus strains
    • Pubmed Central PMCID: 1143769
    • Beasley DW, Whiteman MC, Zhang S, Huang CY, Schneider BS, Smith DR et al (2005) Envelope protein glycosylation status influences mouse neuroinvasion phenotype of genetic lineage 1 West Nile virus strains. J Virol 79(13):8339–8347, Pubmed Central PMCID: 1143769
    • (2005) J Virol , vol.79 , Issue.13 , pp. 8339-8347
    • Beasley, D.W.1    Whiteman, M.C.2    Zhang, S.3    Huang, C.Y.4    Schneider, B.S.5    Smith, D.R.6
  • 36
    • 37449008696 scopus 로고    scopus 로고
    • Immunization with West Nile virus envelope domain III protects mice against lethal infection with homologous and heterologous virus
    • Martina BE, Koraka P, van den Doel P, van Amerongen G, Rimmelzwaan GF, Osterhaus AD (2008) Immunization with West Nile virus envelope domain III protects mice against lethal infection with homologous and heterologous virus. Vaccine 26(2):153–157
    • (2008) Vaccine , vol.26 , Issue.2 , pp. 153-157
    • Martina, B.E.1    Koraka, P.2    van den Doel, P.3    van Amerongen, G.4    Rimmelzwaan, G.F.5    Osterhaus, A.D.6
  • 37
    • 0031714337 scopus 로고    scopus 로고
    • West Nile virus envelope proteins: Nucleotide sequence analysis of strains differing in mouse neuroinvasiveness
    • Chambers TJ, Halevy M, Nestorowicz A, Rice CM, Lustig S (1998) West Nile virus envelope proteins: nucleotide sequence analysis of strains differing in mouse neuroinvasiveness. J Gen Virol 79(Pt 10):2375–2380
    • (1998) J Gen Virol , vol.79 , pp. 2375-2380
    • Chambers, T.J.1    Halevy, M.2    Nestorowicz, A.3    Rice, C.M.4    Lustig, S.5
  • 38
    • 0242580241 scopus 로고    scopus 로고
    • Structural basis of a flavivirus recognized by its neutralizing antibody: Solution structure of the domain III of the Japanese encephalitis virus envelope protein
    • Wu KP, Wu CW, Tsao YP, Kuo TW, Lou YC, Lin CW et al (2003) Structural basis of a flavivirus recognized by its neutralizing antibody: solution structure of the domain III of the Japanese encephalitis virus envelope protein. J Biol Chem 278(46):46007–46013
    • (2003) J Biol Chem , vol.278 , Issue.46 , pp. 46007-46013
    • Wu, K.P.1    Wu, C.W.2    Tsao, Y.P.3    Kuo, T.W.4    Lou, Y.C.5    Lin, C.W.6
  • 39
    • 0029014434 scopus 로고
    • The envelope glycoprotein from tick- borne encephalitis virus at 2 A resolution
    • Rey FA, Heinz FX, Mandl C, Kunz C, Harrison SC (1995) The envelope glycoprotein from tick- borne encephalitis virus at 2 A resolution. Nature 375(6529):291–298
    • (1995) Nature , vol.375 , Issue.6529 , pp. 291-298
    • Rey, F.A.1    Heinz, F.X.2    Mandl, C.3    Kunz, C.4    Harrison, S.C.5
  • 40
    • 57149084450 scopus 로고    scopus 로고
    • A recombinant West Nile virus envelope protein vaccine candidate produced in Spodoptera frugiperda expresSF+ cells
    • Pubmed Central PMCID: 2651515
    • Bonafe N, Rininger JA, Chubet RG, Foellmer HG, Fader S, Anderson JF et al (2009) A recombinant West Nile virus envelope protein vaccine candidate produced in Spodoptera frugiperda expresSF+ cells. Vaccine 27(2):213-222, Pubmed Central PMCID: 2651515
    • (2009) Vaccine , vol.27 , Issue.2 , pp. 213-222
    • Bonafe, N.1    Rininger, J.A.2    Chubet, R.G.3    Foellmer, H.G.4    Fader, S.5    Erson, J.F.6
  • 41
    • 68949129068 scopus 로고    scopus 로고
    • Fusion loop peptide of the West Nile virus envelope protein is essential for pathogenesis and is recognized by a therapeutic cross-reactive human monoclonal antibody
    • Pubmed Central PMCID: 3690769
    • Sultana H, Foellmer HG, Neelakanta G, Oliphant T, Engle M, Ledizet M et al (2009) Fusion loop peptide of the West Nile virus envelope protein is essential for pathogenesis and is recognized by a therapeutic cross-reactive human monoclonal antibody. J Immunol 183(1):650–660, Pubmed Central PMCID: 3690769
    • (2009) J Immunol , vol.183 , Issue.1 , pp. 650-660
    • Sultana, H.1    Foellmer, H.G.2    Neelakanta, G.3    Oliphant, T.4    Engle, M.5    Ledizet, M.6
  • 42
    • 84932192902 scopus 로고    scopus 로고
    • Comprehensive mapping infection- enhancing epitopes of dengue pr protein using polyclonal antibody against prM
    • Pubmed Central PMCID: 4480844
    • Luo Y, Guo X, Yan H, Fang D, Zeng G, Zhou J et al (2015) Comprehensive mapping infection- enhancing epitopes of dengue pr protein using polyclonal antibody against prM. Appl Microbiol Biotechnol 99(14):5917-5927, Pubmed Central PMCID: 4480844
    • (2015) Appl Microbiol Biotechnol , vol.99 , Issue.14 , pp. 5917-5927
    • Luo, Y.1    Guo, X.2    Yan, H.3    Fang, D.4    Zeng, G.5    Zhou, J.6
  • 43
    • 77957201605 scopus 로고    scopus 로고
    • The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complex
    • Pubmed Central PMCID: 2950591
    • Gillespie LK, Hoenen A, Morgan G, Mackenzie JM (2010) The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complex. J Virol 84(20):10438–10447, Pubmed Central PMCID: 2950591
    • (2010) J Virol , vol.84 , Issue.20 , pp. 10438-10447
    • Gillespie, L.K.1    Hoenen, A.2    Morgan, G.3    Mackenzie, J.M.4
  • 44
    • 41349112304 scopus 로고    scopus 로고
    • Structure of the immature dengue virus at low pH primes proteolytic maturation
    • Yu IM, Zhang W, Holdaway HA, Li L, Kostyuchenko VA, Chipman PR et al (2008) Structure of the immature dengue virus at low pH primes proteolytic maturation. Science 319(5871):1834–1837
    • (2008) Science , vol.319 , Issue.5871 , pp. 1834-1837
    • Yu, I.M.1    Zhang, W.2    Holdaway, H.A.3    Li, L.4    Kostyuchenko, V.A.5    Chipman, P.R.6
  • 45
    • 27644481761 scopus 로고    scopus 로고
    • NS1 protein secretion during the acute phase of West Nile virus infection
    • Pubmed Central PMCID: 1280181
    • Macdonald J, Tonry J, Hall RA, Williams B, Palacios G, Ashok MS et al (2005) NS1 protein secretion during the acute phase of West Nile virus infection. J Virol 79(22):13924-13933, Pubmed Central PMCID: 1280181
    • (2005) J Virol , vol.79 , Issue.22 , pp. 13924-13933
    • Macdonald, J.1    Tonry, J.2    Hall, R.A.3    Williams, B.4    Palacios, G.5    Ashok, M.S.6
  • 46
    • 0026069447 scopus 로고
    • The sensitivity of cell-associated dengue virus proteins to trypsin and the detection of trypsinresistant fragments of the nonstructural glycoprotein NS1
    • Cauchi MR, Henchal EA, Wright PJ (1991) The sensitivity of cell-associated dengue virus proteins to trypsin and the detection of trypsinresistant fragments of the nonstructural glycoprotein NS1. Virology 180(2):659–667
    • (1991) Virology , vol.180 , Issue.2 , pp. 659-667
    • Cauchi, M.R.1    Henchal, E.A.2    Wright, P.J.3
  • 47
    • 0028650344 scopus 로고
    • The NS1 protein of tick- borne encephalitis virus forms multimeric species upon secretion from the host cell
    • Crooks AJ, Lee JM, Easterbrook LM, Timofeev AV, Stephenson JR (1994) The NS1 protein of tick- borne encephalitis virus forms multimeric species upon secretion from the host cell. J Gen Virol 75(Pt 12):3453–3460
    • (1994) J Gen Virol , vol.75 , pp. 3453-3460
    • Crooks, A.J.1    Lee, J.M.2    Easterbrook, L.M.3    Timofeev, A.V.4    Stephenson, J.R.5
  • 48
    • 0032994359 scopus 로고    scopus 로고
    • Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation- dependent fashion
    • Pubmed Central PMCID: 112675
    • Flamand M, Megret F, Mathieu M, Lepault J, Rey FA, Deubel V (1999) Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation- dependent fashion. J Virol 73(7):6104–6110, Pubmed Central PMCID: 112675
    • (1999) J Virol , vol.73 , Issue.7 , pp. 6104-6110
    • Flamand, M.1    Megret, F.2    Mathieu, M.3    Lepault, J.4    Rey, F.A.5    Deubel, V.6
  • 49
    • 0023239916 scopus 로고
    • Variation in distribution of the three flavivirus-specified glycoproteins detected by immunofluorescence in infected vero cells
    • Westaway EG, Goodman MR (1987) Variation in distribution of the three flavivirus-specified glycoproteins detected by immunofluorescence in infected vero cells. Arch Virol 94(3-4):215–228
    • (1987) Arch Virol , vol.94 , Issue.3-4 , pp. 215-228
    • Westaway, E.G.1    Goodman, M.R.2
  • 50
    • 77954557986 scopus 로고    scopus 로고
    • The battle between virus and host: Modulation of Toll-like receptor signaling pathways by virus infection
    • 184328Pubmed Central PMCID: 2903949
    • Yokota S, Okabayashi T, Fujii N (2010) The battle between virus and host: modulation of Toll-like receptor signaling pathways by virus infection. Mediators Inflamm 2010:184328, Pubmed Central PMCID: 2903949
    • (2010) Mediators Inflamm 2010
    • Yokota, S.1    Okabayashi, T.2    Fujii, N.3
  • 51
    • 0032768961 scopus 로고    scopus 로고
    • Membrane permeabilization by small hydrophobic nonstructural proteins of Japanese encephalitis virus
    • Pubmed Central PMCID: 112703
    • Chang YS, Liao CL, Tsao CH, Chen MC, Liu CI, Chen LK et al (1999) Membrane permeabilization by small hydrophobic nonstructural proteins of Japanese encephalitis virus. J Virol 73(8):6257–6264, Pubmed Central PMCID: 112703
    • (1999) J Virol , vol.73 , Issue.8 , pp. 6257-6264
    • Chang, Y.S.1    Liao, C.L.2    Tsao, C.H.3    Chen, M.C.4    Liu, C.I.5    Chen, L.K.6
  • 52
    • 34249722201 scopus 로고    scopus 로고
    • Mutations in West Nile virus nonstructural proteins that facilitate replicon persistence in vitro attenuate virus replication in vitro and in vivo
    • Rossi SL, Fayzulin R, Dewsbury N, Bourne N, Mason PW (2007) Mutations in West Nile virus nonstructural proteins that facilitate replicon persistence in vitro attenuate virus replication in vitro and in vivo. Virology 364(1):184–195
    • (2007) Virology , vol.364 , Issue.1 , pp. 184-195
    • Rossi, S.L.1    Fayzulin, R.2    Dewsbury, N.3    Bourne, N.4    Mason, P.W.5
  • 53
    • 43249124059 scopus 로고    scopus 로고
    • Role of nonstructural protein NS2A in flavivirus assembly
    • Pubmed Central PMCID: 2346727
    • Leung JY, Pijlman GP, Kondratieva N, Hyde J, Mackenzie JM, Khromykh AA (2008) Role of nonstructural protein NS2A in flavivirus assembly. J Virol 82(10):4731–4741, Pubmed Central PMCID: 2346727
    • (2008) J Virol , vol.82 , Issue.10 , pp. 4731-4741
    • Leung, J.Y.1    Pijlman, G.P.2    Kondratieva, N.3    Hyde, J.4    Mackenzie, J.M.5    Khromykh, A.A.6
  • 54
    • 13744254078 scopus 로고    scopus 로고
    • Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins
    • Pubmed Central PMCID: 544092
    • Liu WJ, Wang XJ, Mokhonov VV, Shi PY, Randall R, Khromykh AA (2005) Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins. J Virol 79(3):1934–1942, Pubmed Central PMCID: 544092
    • (2005) J Virol , vol.79 , Issue.3 , pp. 1934-1942
    • Liu, W.J.1    Wang, X.J.2    Mokhonov, V.V.3    Shi, P.Y.4    Randall, R.5    Khromykh, A.A.6
  • 56
    • 23844507858 scopus 로고    scopus 로고
    • Role of RNA structures present at the 3’UTR of dengue virus on translation, RNA synthesis, and viral replication
    • Alvarez DE, De Lella Ezcurra AL, Fucito S, Gamarnik AV (2005) Role of RNA structures present at the 3’UTR of dengue virus on translation, RNA synthesis, and viral replication. Virology 339(2):200–212
    • (2005) Virology , vol.339 , Issue.2 , pp. 200-212
    • Alvarez, D.E.1    De Lella Ezcurra, A.L.2    Fucito, S.3    Gamarnik, A.V.4
  • 57
    • 0027499688 scopus 로고
    • Deletion analysis of dengue virus type 4 nonstructural protein NS2B: Identification of a domain required for NS2B-NS3 protease activity
    • Pubmed Central PMCID: 240272
    • Falgout B, Miller RH, Lai CJ (1993) Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity. J Virol 67(4):2034–2042, Pubmed Central PMCID: 240272
    • (1993) J Virol , vol.67 , Issue.4 , pp. 2034-2042
    • Falgout, B.1    Miller, R.H.2    Lai, C.J.3
  • 58
    • 0034734773 scopus 로고    scopus 로고
    • Yellow fever virus NS2B-NS3 protease: Charged-to-alanine mutagenesis and deletion analysis define regions important for protease complex formation and function
    • Droll DA, Krishna Murthy HM, Chambers TJ (2000) Yellow fever virus NS2B-NS3 protease: charged-to-alanine mutagenesis and deletion analysis define regions important for protease complex formation and function. Virology 275(2):335–347
    • (2000) Virology , vol.275 , Issue.2 , pp. 335-347
    • Droll, D.A.1    Krishna Murthy, H.M.2    Chambers, T.J.3
  • 59
  • 60
    • 45549101510 scopus 로고    scopus 로고
    • Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity
    • Chappell KJ, Stoermer MJ, Fairlie DP, Young PR (2008) Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity. J Gen Virol 89(Pt 4):1010–1014
    • (2008) J Gen Virol , vol.89 , pp. 1010-1014
    • Chappell, K.J.1    Stoermer, M.J.2    Fairlie, D.P.3    Young, P.R.4
  • 61
    • 0034616194 scopus 로고    scopus 로고
    • Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro
    • Yusof R, Clum S, Wetzel M, Murthy HM, Padmanabhan R (2000) Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro. J Biol Chem 275(14):9963–9969
    • (2000) J Biol Chem , vol.275 , Issue.14 , pp. 9963-9969
    • Yusof, R.1    Clum, S.2    Wetzel, M.3    Murthy, H.M.4    Padmanabhan, R.5
  • 62
    • 58649113845 scopus 로고    scopus 로고
    • Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformation
    • Robin G, Chappell K, Stoermer MJ, Hu SH, Young PR, Fairlie DP et al (2009) Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation. J Mol Biol 385(5):1568–1577
    • (2009) J Mol Biol , vol.385 , Issue.5 , pp. 1568-1577
    • Robin, G.1    Chappell, K.2    Stoermer, M.J.3    Hu, S.H.4    Young, P.R.5    Fairlie, D.P.6
  • 63
    • 84855921187 scopus 로고    scopus 로고
    • Ligand- bound structures of the dengue virus protease reveal the active conformation
    • Pubmed Central PMCID: 3255909
    • Noble CG, Seh CC, Chao AT, Shi PY (2012) Ligand- bound structures of the dengue virus protease reveal the active conformation. J Virol 86(1):438–446, Pubmed Central PMCID: 3255909
    • (2012) J Virol , vol.86 , Issue.1 , pp. 438-446
    • Noble, C.G.1    Seh, C.C.2    Chao, A.T.3    Shi, P.Y.4
  • 64
    • 70349337005 scopus 로고    scopus 로고
    • NS4A regulates the ATPase activity of the NS3 helicase: A novel cofactor role of the non-structural protein NS4A from West Nile virus
    • Pubmed Central PMCID: 2887571
    • Shiryaev SA, Chernov AV, Aleshin AE, Shiryaeva TN, Strongin AY (2009) NS4A regulates the ATPase activity of the NS3 helicase: a novel cofactor role of the non-structural protein NS4A from West Nile virus. J Gen Virol 90(Pt 9):2081–2085, Pubmed Central PMCID: 2887571
    • (2009) J Gen Virol , vol.90 , pp. 2081-2085
    • Shiryaev, S.A.1    Chernov, A.V.2    Aleshin, A.E.3    Shiryaeva, T.N.4    Strongin, A.Y.5
  • 65
    • 1842850947 scopus 로고    scopus 로고
    • The nonstructural 3 (NS3) protein of dengue virus type 2 interacts with human nuclear receptor binding protein and is associated with alterations in membrane structure
    • Chua JJ, Ng MM, Chow VT (2004) The nonstructural 3 (NS3) protein of dengue virus type 2 interacts with human nuclear receptor binding protein and is associated with alterations in membrane structure. Virus Res 102(2):151–163
    • (2004) Virus Res , vol.102 , Issue.2 , pp. 151-163
    • Chua, J.J.1    Ng, M.M.2    Chow, V.T.3
  • 66
    • 84863288600 scopus 로고    scopus 로고
    • Mutational analysis of the West Nile virus NS4B protein
    • Pubmed Central PMCID: 4583194
    • Wicker JA, Whiteman MC, Beasley DW, Davis CT, McGee CE, Lee JC et al (2012) Mutational analysis of the West Nile virus NS4B protein. Virology 426(1):22–33, Pubmed Central PMCID: 4583194
    • (2012) Virology , vol.426 , Issue.1 , pp. 22-33
    • Wicker, J.A.1    Whiteman, M.C.2    Beasley, D.W.3    Davis, C.T.4    McGee, C.E.5    Lee, J.C.6
  • 67
    • 84905184081 scopus 로고    scopus 로고
    • Induction of endoplasmic reticulum- derived replication-competent membrane structures by West Nile virus nonstructural protein 4B
    • Pubmed Central PMCID: 3896337
    • Kaufusi PH, Kelley JF, Yanagihara R, Nerurkar VR (2014) Induction of endoplasmic reticulum- derived replication-competent membrane structures by West Nile virus nonstructural protein 4B. PLoS One 9(1), e84040, Pubmed Central PMCID: 3896337
    • (2014) Plos One , vol.9 , Issue.1
    • Kaufusi, P.H.1    Kelley, J.F.2    Yanagihara, R.3    Nerurkar, V.R.4
  • 68
    • 0027475018 scopus 로고
    • Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site
    • Pubmed Central PMCID: 240389
    • Lin C, Amberg SM, Chambers TJ, Rice CM (1993) Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site. J Virol 67(4):2327–2335, Pubmed Central PMCID: 240389
    • (1993) J Virol , vol.67 , Issue.4 , pp. 2327-2335
    • Lin, C.1    Amberg, S.M.2    Chambers, T.J.3    Rice, C.M.4
  • 69
    • 68649103985 scopus 로고    scopus 로고
    • Chapter 2. New insights into flavivirus nonstructural protein 5
    • Davidson AD (2009) Chapter 2. New insights into flavivirus nonstructural protein 5. Adv Virus Res 74:41–101
    • (2009) Adv Virus Res , vol.74 , pp. 41-101
    • Davidson, A.D.1
  • 70
    • 42449160175 scopus 로고    scopus 로고
    • West Nile virus methyltransferase catalyzes two methylations of the viral RNA cap through a substrate-repositioning mechanism
    • Pubmed Central PMCID: 2293060
    • Dong H, Ren S, Zhang B, Zhou Y, Puig- Basagoiti F, Li H et al (2008) West Nile virus methyltransferase catalyzes two methylations of the viral RNA cap through a substrate-repositioning mechanism. J Virol 82(9):4295-4307, Pubmed Central PMCID: 2293060
    • (2008) J Virol , vol.82 , Issue.9 , pp. 4295-4307
    • Dong, H.1    Ren, S.2    Zhang, B.3    Zhou, Y.4    Puig-Basagoiti, F.5    Li, H.6
  • 71
    • 84879212808 scopus 로고    scopus 로고
    • Pathology and tissue tropism of natural West Nile virus infection in birds: A review
    • Pubmed Central PMCID: 3686667
    • Gamino V, Hofle U (2013) Pathology and tissue tropism of natural West Nile virus infection in birds: a review. Vet Res 44:39, Pubmed Central PMCID: 3686667
    • (2013) Vet Res , vol.44 , pp. 39
    • Gamino, V.1    Hofle, U.2
  • 72
    • 33748654413 scopus 로고    scopus 로고
    • Host heterogeneity dominates West Nile virus transmission
    • Pubmed Central PMCID: 1636093
    • Kilpatrick AM, Daszak P, Jones MJ, Marra PP, Kramer LD (2006) Host heterogeneity dominates West Nile virus transmission. Proc Biol Sci 273(1599):2327–2333, Pubmed Central PMCID: 1636093
    • (2006) Proc Biol Sci , vol.273 , Issue.1599 , pp. 2327-2333
    • Kilpatrick, A.M.1    Daszak, P.2    Jones, M.J.3    Marra, P.P.4    Kramer, L.D.5
  • 73
    • 35548969712 scopus 로고    scopus 로고
    • Tissue tropism and neuroinvasion of West Nile virus do not differ for two mouse strains with different survival rates
    • Pubmed Central PMCID: 2814419
    • Brown AN, Kent KA, Bennett CJ, Bernard KA (2007) Tissue tropism and neuroinvasion of West Nile virus do not differ for two mouse strains with different survival rates. Virology 368(2):422–430, Pubmed Central PMCID: 2814419
    • (2007) Virology , vol.368 , Issue.2 , pp. 422-430
    • Brown, A.N.1    Kent, K.A.2    Bennett, C.J.3    Bernard, K.A.4
  • 75
    • 4544266363 scopus 로고    scopus 로고
    • Infectious entry of West Nile virus occurs through a clathrinmediated endocytic pathway
    • Pubmed Central PMCID: 516396
    • Chu JJ, Ng ML (2004) Infectious entry of West Nile virus occurs through a clathrinmediated endocytic pathway. J Virol 78(19):10543–10555, Pubmed Central PMCID: 516396
    • (2004) J Virol , vol.78 , Issue.19 , pp. 10543-10555
    • Chu, J.J.1    Ng, M.L.2
  • 76
    • 11144227268 scopus 로고    scopus 로고
    • Interaction of West Nile virus with alpha v beta 3 integrin mediates virus entry into cells
    • Chu JJ, Ng ML (2004) Interaction of West Nile virus with alpha v beta 3 integrin mediates virus entry into cells. J Biol Chem 279(52):54533–54541
    • (2004) J Biol Chem , vol.279 , Issue.52 , pp. 54533-54541
    • Chu, J.J.1    Ng, M.L.2
  • 77
    • 0024023266 scopus 로고
    • Association between the pH-dependent conformational change of West Nile flavivirus E protein and virus-mediated membrane fusion
    • Kimura T, Ohyama A (1988) Association between the pH-dependent conformational change of West Nile flavivirus E protein and virus-mediated membrane fusion. J Gen Virol 69(Pt 6):1247–1254
    • (1988) J Gen Virol , vol.69 , pp. 1247-1254
    • Kimura, T.1    Ohyama, A.2
  • 78
    • 36248956148 scopus 로고    scopus 로고
    • West Nile virus-induced cytoplasmic membrane structures provide partial protection against the interferon-induced antiviral MxA protein
    • Hoenen A, Liu W, Kochs G, Khromykh AA, Mackenzie JM (2007) West Nile virus-induced cytoplasmic membrane structures provide partial protection against the interferon-induced antiviral MxA protein. J Gen Virol 88(Pt 11):3013–3017
    • (2007) J Gen Virol , vol.88 , pp. 3013-3017
    • Hoenen, A.1    Liu, W.2    Kochs, G.3    Khromykh, A.A.4    Mackenzie, J.M.5
  • 79
    • 0032863958 scopus 로고    scopus 로고
    • Markers for trans-Golgi membranes and the intermediate compartment localize to induced membranes with distinct replication functions in flavivirus-infected cells
    • Pubmed Central PMCID: 112990
    • Mackenzie JM, Jones MK, Westaway EG (1999) Markers for trans-Golgi membranes and the intermediate compartment localize to induced membranes with distinct replication functions in flavivirus-infected cells. J Virol 73(11):9555–9567, Pubmed Central PMCID: 112990
    • (1999) J Virol , vol.73 , Issue.11 , pp. 9555-9567
    • Mackenzie, J.M.1    Jones, M.K.2    Westaway, E.G.3
  • 80
    • 34047171495 scopus 로고    scopus 로고
    • West Nile virus strain Kunjin NS5 polymerase is a phosphoprotein localized at the cytoplasmic site of viral RNA synthesis
    • Mackenzie JM, Kenney MT, Westaway EG (2007) West Nile virus strain Kunjin NS5 polymerase is a phosphoprotein localized at the cytoplasmic site of viral RNA synthesis. J Gen Virol 88(Pt 4):1163–1168
    • (2007) J Gen Virol , vol.88 , pp. 1163-1168
    • Mackenzie, J.M.1    Kenney, M.T.2    Westaway, E.G.3
  • 81
    • 0032486487 scopus 로고    scopus 로고
    • Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A
    • Mackenzie JM, Khromykh AA, Jones MK, Westaway EG (1998) Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A. Virology 245(2):203–215
    • (1998) Virology , vol.245 , Issue.2 , pp. 203-215
    • Mackenzie, J.M.1    Khromykh, A.A.2    Jones, M.K.3    Westaway, E.G.4
  • 82
    • 33646167045 scopus 로고    scopus 로고
    • Regulated cleavages at the West Nile virus NS4A-2K-NS4B junctions play a major role in rearranging cytoplasmic membranes and Golgi trafficking of the NS4A protein
    • Pubmed Central PMCID: 1472005
    • Roosendaal J, Westaway EG, Khromykh A, Mackenzie JM (2006) Regulated cleavages at the West Nile virus NS4A-2K-NS4B junctions play a major role in rearranging cytoplasmic membranes and Golgi trafficking of the NS4A protein. J Virol 80(9):4623–4632, Pubmed Central PMCID: 1472005
    • (2006) J Virol , vol.80 , Issue.9 , pp. 4623-4632
    • Roosendaal, J.1    Westaway, E.G.2    Khromykh, A.3    Mackenzie, J.M.4
  • 83
    • 84885392596 scopus 로고    scopus 로고
    • Non-specific dsRNA-mediated antiviral response in the honey bee
    • Pubmed Central PMCID: 3795074
    • Flenniken ML, Andino R (2013) Non-specific dsRNA-mediated antiviral response in the honey bee. PLoS One 8(10), e77263, Pubmed Central PMCID: 3795074
    • (2013) Plos One , vol.8 , Issue.10
    • Flenniken, M.L.1    Ino, R.2
  • 84
    • 33744539798 scopus 로고    scopus 로고
    • Toll-like receptors and RNA helicases: Two parallel ways to trigger antiviral responses
    • Meylan E, Tschopp J (2006) Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Mol Cell 22(5): 561–569
    • (2006) Mol Cell , vol.22 , Issue.5 , pp. 561-569
    • Meylan, E.1    Tschopp, J.2
  • 85
    • 84871941263 scopus 로고    scopus 로고
    • The West Nile virus capsid protein blocks apoptosis through a phosphatidylinositol 3-kinasedependent mechanism
    • Pubmed Central PMCID: 3554064
    • Urbanowski MD, Hobman TC (2013) The West Nile virus capsid protein blocks apoptosis through a phosphatidylinositol 3-kinasedependent mechanism. J Virol 87(2):872-881, Pubmed Central PMCID: 3554064
    • (2013) J Virol , vol.87 , Issue.2 , pp. 872-881
    • Urbanowski, M.D.1    Hobman, T.C.2
  • 86
    • 0028121374 scopus 로고
    • Regulation of vascular endothelial barrier function
    • Lum H, Malik AB (1994) Regulation of vascular endothelial barrier function. Am J Physiol 267(3 Pt 1):L223–L241
    • (1994) Am J Physiol , vol.267 , Issue.3 , pp. L223-L241
    • Lum, H.1    Malik, A.B.2
  • 87
    • 66149122202 scopus 로고    scopus 로고
    • West nile virus capsid degradation of claudin proteins disrupts epithelial barrier function
    • Pubmed Central PMCID: 2687390
    • Medigeshi GR, Hirsch AJ, Brien JD, Uhrlaub JL, Mason PW, Wiley C et al (2009) West nile virus capsid degradation of claudin proteins disrupts epithelial barrier function. J Virol 83(12):6125–6134, Pubmed Central PMCID: 2687390
    • (2009) J Virol , vol.83 , Issue.12 , pp. 6125-6134
    • Medigeshi, G.R.1    Hirsch, A.J.2    Brien, J.D.3    Uhrlaub, J.L.4    Mason, P.W.5    Wiley, C.6
  • 88
    • 33144482922 scopus 로고    scopus 로고
    • A single amino acid substitution in the West Nile virus nonstructural protein NS2A disables its ability to inhibit alpha/beta interferon induction and attenuates virus virulence in mice
    • Pubmed Central PMCID: 1395377
    • Liu WJ, Wang XJ, Clark DC, Lobigs M, Hall RA, Khromykh AA (2006) A single amino acid substitution in the West Nile virus nonstructural protein NS2A disables its ability to inhibit alpha/beta interferon induction and attenuates virus virulence in mice. J Virol 80(5):2396-2404, Pubmed Central PMCID: 1395377
    • (2006) J Virol , vol.80 , Issue.5 , pp. 2396-2404
    • Liu, W.J.1    Wang, X.J.2    Clark, D.C.3    Lobigs, M.4    Hall, R.A.5    Khromykh, A.A.6
  • 89
    • 0034101043 scopus 로고    scopus 로고
    • Modulation of dengue virus infection in human cells by alpha, beta, and gamma interferons
    • Pubmed Central PMCID: 110847
    • Diamond MS, Roberts TG, Edgil D, Lu B, Ernst J, Harris E (2000) Modulation of dengue virus infection in human cells by alpha, beta, and gamma interferons. J Virol 74(11):4957–4966, Pubmed Central PMCID: 110847
    • (2000) J Virol , vol.74 , Issue.11 , pp. 4957-4966
    • Diamond, M.S.1    Roberts, T.G.2    Edgil, D.3    Lu, B.4    Ernst, J.5    Harris, E.6
  • 90
    • 0031007621 scopus 로고    scopus 로고
    • Inhibition of Japanese encephalitis virus infection by nitric oxide: Antiviral effect of nitric oxide on RNA virus replication
    • Pubmed Central PMCID: 191758
    • Lin YL, Huang YL, Ma SH, Yeh CT, Chiou SY, Chen LK et al (1997) Inhibition of Japanese encephalitis virus infection by nitric oxide: antiviral effect of nitric oxide on RNA virus replication. J Virol 71(7):5227–5235, Pubmed Central PMCID: 191758
    • (1997) J Virol , vol.71 , Issue.7 , pp. 5227-5235
    • Lin, Y.L.1    Huang, Y.L.2    Ma, S.H.3    Yeh, C.T.4    Chiou, S.Y.5    Chen, L.K.6
  • 91
    • 77951063838 scopus 로고    scopus 로고
    • Antagonism of the complement component C4 by flavivirus nonstructural protein NS1
    • Pubmed Central PMCID: 2856034
    • Avirutnan P, Fuchs A, Hauhart RE, Somnuke P, Youn S, Diamond MS et al (2010) Antagonism of the complement component C4 by flavivirus nonstructural protein NS1. J Exp Med 207(4):793–806, Pubmed Central PMCID: 2856034
    • (2010) J Exp Med , vol.207 , Issue.4 , pp. 793-806
    • Avirutnan, P.1    Fuchs, A.2    Hauhart, R.E.3    Somnuke, P.4    Youn, S.5    Diamond, M.S.6
  • 92
    • 79960404180 scopus 로고    scopus 로고
    • Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activation
    • Pubmed Central PMCID: 3119735
    • Avirutnan P, Hauhart RE, Somnuke P, Blom AM, Diamond MS, Atkinson JP (2011) Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activation. J Immunol 187(1):424-433, Pubmed Central PMCID: 3119735
    • (2011) J Immunol , vol.187 , Issue.1 , pp. 424-433
    • Avirutnan, P.1    Hauhart, R.E.2    Somnuke, P.3    Blom, A.M.4    Diamond, M.S.5    Atkinson, J.P.6
  • 93
    • 0025102185 scopus 로고
    • Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis
    • Pubmed Central PMCID: 247903
    • Falgout B, Bray M, Schlesinger JJ, Lai CJ (1990) Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis. J Virol 64(9):4356-4363, Pubmed Central PMCID: 247903
    • (1990) J Virol , vol.64 , Issue.9 , pp. 4356-4363
    • Falgout, B.1    Bray, M.2    Schlesinger, J.J.3    Lai, C.J.4
  • 94
    • 0036891872 scopus 로고    scopus 로고
    • Identification of neutralizing epitopes within structural domain III of the West Nile virus envelope protein
    • Pubmed Central PMCID: 136710
    • Beasley DW, Barrett AD (2002) Identification of neutralizing epitopes within structural domain III of the West Nile virus envelope protein. J Virol 76(24):13097–13100, Pubmed Central PMCID: 136710
    • (2002) J Virol , vol.76 , Issue.24 , pp. 13097-13100
    • Beasley, D.W.1    Barrett, A.D.2
  • 95
    • 79956329810 scopus 로고    scopus 로고
    • Neutralization escape variant of West Nile virus associated with altered peripheral pathogenicity and differential cytokine profile
    • Sapkal GN, Harini S, Ayachit VM, Fulmali PV, Mahamuni SA, Bondre VP et al (2011) Neutralization escape variant of West Nile virus associated with altered peripheral pathogenicity and differential cytokine profile. Virus Res 158(1-2):130–139
    • (2011) Virus Res , vol.158 , Issue.1-2 , pp. 130-139
    • Sapkal, G.N.1    Harini, S.2    Ayachit, V.M.3    Fulmali, P.V.4    Mahamuni, S.A.5    Bondre, V.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.