Ligand-bound structures of the dengue virus protease reveal the active conformation

Journal of Virology

Volumn 86, Issue 1, 2012, Pages 438-446

  Noble, Christian G ^a   Seh, Cheah Chen ^a   Chao, Alexander T ^a   Shi, Pei Yong ^a  

^a Novartis Institute for Tropical Diseases   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 2B; NONSTRUCTURAL PROTEIN 3; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DENGUE VIRUS 3; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HYDROGEN BOND; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEROTYPE; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS; WEST NILE FLAVIVIRUS;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CRYSTALLIZATION; DENGUE VIRUS; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PROTEIN BINDING; PROTEIN CONFORMATION; SERINE ENDOPEPTIDASES; VIRAL NONSTRUCTURAL PROTEINS;

DENGUE VIRUS; FLAVIVIRUS; WEST NILE VIRUS;

EID: 84855921187     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.06225-11     Document Type: Article

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