Fusion Loop Peptide of the West Nile virus envelope protein is essential for pathogenesis and is recognized by a therapeutic cross-reactive human monoclonal antibody

Journal of Immunology

Volumn 183, Issue 1, 2009, Pages 650-660

  Sultana, Hameeda ^a   Foellmer, Harald G ^a   Neelakanta, Girish ^a   Oliphant, Theodore ^c   Engle, Michael ^c   Ledizet, Michel ^b   Krishnan, Manoj N ^a   Bonafé, Nathalie ^b   Anthony, Karen G ^b   Marasco, Wayne A ^d   Kaplan, Paul ^b   Montgomery, Ruth R ^a   Diamond, Michael S ^c   Koski, Raymond A ^b   Fikrig, Erol ^a,e  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b L2 Diagnostics LLC   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 11; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; HYBRID PROTEIN; PEPTIDE; VIRUS FUSION PROTEIN;

ANIMAL CELL; ARTICLE; ASSAY; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CROSS REACTION; DENGUE VIRUS; EPITOPE MAPPING; INFLAMMATION; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; VIRUS ENCEPHALITIS; VIRUS IMMUNITY; VIRUS MUTANT; VIRUS NEUTRALIZATION; VIRUS PATHOGENESIS; VIRUS VIRULENCE; WEST NILE FLAVIVIRUS; ANIMAL; ANTIBODY COMBINING SITE; BAGG ALBINO MOUSE; C57BL MOUSE; CELL LINE; FEMALE; HUMAN; IMMUNOLOGY; METABOLISM; PATHOGENICITY; PROTEIN TERTIARY STRUCTURE; VIROLOGY; VIRUS INFECTION;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES, ANTIBODY; CELL LINE; CROSS REACTIONS; DENGUE VIRUS; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; VIRAL ENVELOPE PROTEINS; VIRAL FUSION PROTEINS; WEST NILE FEVER; WEST NILE VIRUS;

EID: 68949129068     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900093     Document Type: Article

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